ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna0540 | UUCAAUAUAAAGGCUGGCG AAGUUAUAUUUCCGACCGC |
37 | 8 | 29 | LRRK2 | Parkinsons disease (PD) | c.4321C>G,p.Arg1441Gly | rs33939927 | ![]() |
|
aspsirna0541 | GCUGGCGCUUCUUCUUCCC CGACCGCGAAGAAGAAGGG |
71 | 10 | 61 | LRRK2 | Parkinsons disease (PD) | c.4321C>G,p.Arg1441Gly | rs33939927 | ![]() |
|
aspsirna0542 | UAAAGGCUGGCGCUUCUUC AUUUCCGACCGCGAAGAAG |
20 | 6 | 14 | LRRK2 | Parkinsons disease (PD) | c.4321C>G,p.Arg1441Gly | rs33939927 | ![]() |