ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna0041 | GAGAUGGGGACAGUACUUC CUCUACCCCUGUCAUGAAG |
70 | 28 | 42 | HTT | Huntington disease (HD) | c.5165C>A,c.52CAG(36_39) | rs363125 | ![]() |
|
aspsirna0042 | GAGAUGGGGACAGUAAUUC CUCUACCCCUGUCAUUAAG |
70 | 22 | 48 | HTT | Huntington disease (HD) | c.5165C>A,c.52CAG(36_39) | rs363125 | ![]() |
|
aspsirna0043 | GGACAGUACUUCAACGCUA CCUGUCAUGAAGUUGCGAU |
94 | 50 | 44 | HTT | Huntington disease (HD) | c.5165C>A,c.52CAG(36_39) | rs363125 | ![]() |
|
aspsirna0044 | GGACAGUAAUUCAACGCUA CCUGUCAUUAAGUUGCGAU |
50 | 92 | -42 | HTT | Huntington disease (HD) | c.5165C>A,c.52CAG(36_39) | rs363125 | ![]() |
|
aspsirna0045 | GGACAGUACAUCAACGCUA CCUGUCAUGUAGUUGCGAU |
90 | 60 | 30 | HTT | Huntington disease (HD) | c.5165C>A,c.52CAG(36_39) | rs363125 | ![]() |
|
aspsirna0046 | GGACAGUAAGUCAACGCUA CCUGUCAUUCAGUUGCGAU |
55 | 82 | -27 | HTT | Huntington disease (HD) | c.5165C>A,c.52CAG(36_39) | rs363125 | ![]() |