VIRsiRNAdb

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Total number of Results for Replicase are 3
Results from 0 - 25

siRNA sequence "gcacuugucuaccuugaug" alignment with "SARS Coronavirus" virus reference Genome sequences
siRNA sequence matching with "gcacuugucuaccuugaug" SARS Coronavirus" Virus reference Genome sequences
Browse all the records for "SARS Coronavirus" virus
Browse "virsi1331 " record
Length: 19
GC Content:47 %
Strain of Virus: GZ50
GenBank Acc: AY304495
Transfection Reagent: Oligofectamine
Incubation Time (Hours):24

Offtargets for "gcacuugucuaccuugaug" siRNA in Human Genome sequences
See AY304495 at Genbank
Pubmed:16638566
Article:Kinetics and synergistic effects of siRNAs targeting structural and replicase genes of SARS-associated coronavirus.
Authors:He ML, Zheng BJ, Chen Y, Wong KL, Huang JD, Lin MC, Peng Y, Yuen KY, Sung JJ, Kung HF.
Journal:FEBS Lett. 2006 May 1;580(10):2414-20. Epub 2006 Mar 30.
Entrez:16638566

siRNA sequence "ccugauuggcaugcuacag" alignment with "Hepatitis E Virus [HEV]" virus reference Genome sequences
siRNA sequence matching with "ccugauuggcaugcuacag" Hepatitis E Virus [HEV]" Virus reference Genome sequences
Browse all the records for "Hepatitis E Virus [HEV]" virus
Browse "virsi2194 " record
Length: 19
GC Content:53 %
GenBank Acc: AF076239
Transfection Reagent: Lipofectamine 2000 / FuGENE 6
Incubation Time (Hours):72

Offtargets for "ccugauuggcaugcuacag" siRNA in Human Genome sequences
See AF076239 at Genbank
Pubmed:20105445
Article:Inhibition of Hepatitis E virus replication using short hairpin RNA (shRNA).
Authors:Kumar A, Panda SK, Durgapal H, Acharya SK, Rehman S, Kar UK.
Journal:Antiviral Res. 2010 Mar;85(3):541-50. Epub 2010 Jan 25.
Entrez:20105445

siRNA sequence "caaguucaccacaggugag" alignment with "Hepatitis E Virus [HEV]" virus reference Genome sequences
siRNA sequence matching with "caaguucaccacaggugag" Hepatitis E Virus [HEV]" Virus reference Genome sequences
Browse all the records for "Hepatitis E Virus [HEV]" virus
Browse "virsi2193 " record
Length: 19
GC Content:53 %
GenBank Acc: AF076239
Transfection Reagent: Lipofectamine 2000 / FuGENE 6
Incubation Time (Hours):72

Offtargets for "caaguucaccacaggugag" siRNA in Human Genome sequences
See AF076239 at Genbank
Pubmed:20105445
Article:Inhibition of Hepatitis E virus replication using short hairpin RNA (shRNA).
Authors:Kumar A, Panda SK, Durgapal H, Acharya SK, Rehman S, Kar UK.
Journal:Antiviral Res. 2010 Mar;85(3):541-50. Epub 2010 Jan 25.
Entrez:20105445


VIRsiRNAid	siRNA Sequence	Virus_Name	Target Region	Cell Line	Test Object	Efficacy	PMID	Offtarget	Align With	ALIGN0 Result
virsi1331	gcacuugucuaccuugaug	SARS Coronavirus	Replicase	FRhK-4	RNA	90	16638566	Blast SL	refseqs
virsi2194	ccugauuggcaugcuacag	Hepatitis E Virus [HEV]	Replicase	HepG2	Protein	75	20105445	Blast SL	refseqs
virsi2193	caaguucaccacaggugag	Hepatitis E Virus [HEV]	Replicase	HepG2	Protein	58	20105445	Blast SL	refseqs



: siRNA specific for both strands
: siRNA specific for only one strands
: siRNA Not specific
SL: siRNA seedlocator algorithm