Name Description Institute

PROPRED1

The aim of this server is to predict MHC Class-I binding regions in an antigen sequence (Singh, H. and Raghava, G.P.S. (2003) Bioinformatics, 19 1009)

CSIR-IMTECH

nHLApred

The aim of this server is to predict MHC Class-II binding regions in an antigen sequence (Singh, H. and Raghava, G. P. S. (2001) Bioinformatics 17 1236)

CSIR-IMTECH

MMBpred

The BcePred server predict B cell epitope based on physio-chemical properties of amino acids. (Saha,S and Raghava GP (2004) ICARIS, LNCS 3239,197-204)

CSIR-IMTECH

Pcleavage

This server allow to predict binding peptide for 67 MHC Class I alleles. This also allow to predict the proteasome cleavage site and binding peptide that have cleavage site at C terminus (potential T cell epitopes). This uses the hybrid approach for prediction (Neural Network + Quantitative Matrix)

CSIR-IMTECH

TAPpred

SVM and ANN based methods for predicting HLA-DRB1*0401 binding peptides in an Antigen Sequence (Bhasin, M. and Raghava, G.P.S. (2003) Bioinformatics 20421).

CSIR-IMTECH

CTLpred

ABCpred server is to predict linear B cell epitope regions in an antigen sequence, using artificial neural network. This server will assist in locating epitope regions that are useful in selecting synthetic vaccine candidates, disease diagonosis and also in allergy research. ( Saha, S. and Raghava, G. P. S. (2006) PROTEINSStructure, Function, and Bioinformatics (In Press) )

CSIR-IMTECH

PROPRED

Prediction of of MHC class I binders which can bind to wide range of MHC alleles with high affinity. This server has potential to develop sub-unit vaccine for large population (Bhasin, M., and Raghava, G.P.S. (2003) Hybridoma and Hybridomics 22 229)

CSIR-IMTECH

HLADR4pred

Prediction of binders for MHC class II alleles. This allows to predict promiscuous class binders, which can bind to large number of MHC Class II alleles.

CSIR-IMTECH

MHC2pred

Bcipep is a collection of the peptides having the role in Humoral immunity. The peptides in the database has varying measure of immunogenicity.This database can assist in the development of method for predicting B cell epitopes, desigining synthetic vaccines and in disease diagnosis. This databse is also launched by European Bioinformatics Institute (EBI) Hinxton, Cambridge, UK. (Saha S, Bhasin M, Raghava GP. (2005) BMC Genomics. 6(1)79)

CSIR-IMTECH

MHC

This server allows server to predict proten (Immuno and standard) (Bhasin M, Raghava GP. (2005) Nucleic Acids Res.33(Web Server issue)W202-7)

CSIR-IMTECH

MHCbench

Matrix Optimization Technique for Predicting MHC binding Core (Singh, H. and Raghava, G. P. S. (2002) Biotech Software and Internet Report, 3146)

CSIR-IMTECH

AbAg

CSIR-IMTECH

BCEpred

A server for predicting binders for MHC class I and II alleles. It also search these predicted binders in various genomes.

CSIR-IMTECH

ABCpred

TAPPred is an on-line service for predicting binding affinity of peptides toward the TAP transporter. The Prediction is based on cascade SVM, using sequence and properties of the the amino acids (Bhasin, M. and Raghava, G. P. S. (2004) Protein Science 13596-607).

CSIR-IMTECH

BCIPep

It is an interface developed for evaluating the Major Histocompatibility Complex (MHC) binding peptide prediction algorithms.

CSIR-IMTECH

HLApred

The MHCBN is a curated database consisting of detailed information about Major Histocompatibility Complex (MHC) Binding,Non-binding peptides and T-cell epitopes.The version 3.1 of database provides information about peptides interacting with TAP and MHC linked autoimmune diseases This databse is also launched by European Bioinformatics Institute (EBI) Hinxton, Cambridge, UK. (Bhasin, M., Singh, H. and Raghava, G. P. S. (2003) Bioinformatics 19 665).

CSIR-IMTECH

MHCBN

Direct method of prediction of CTL Epitopes in an antigen sequence. This server utlize the machine learning techniques Support Vector Machine(SVM) and Aritificial Neural Network (ANN) for prediction (Bhasin, M. and Raghava, G. P. S. (2004) Vaccine 223195-204 )

CSIR-IMTECH

HaptenDB

This web-server allow to compute the endpoint titer and concentration of Antibody(Ab) or Antigen(Ag) from ELISA data(Raghava, G. P. S. and Agrewala, J. N. (2001) Biotech Software and Internet Report, 2196). This server is based on graphical method developed for calculating Ab/Ag concentration (Raghava, G.P.S., Joshi, A.K. and Agrewala, J.N. (1992) J. Immunol. Methods 153, 263-264).

CSIR-IMTECH

HLA_affi

This is a SVM based server developed for predicting the binding affinity of peptides binding to HLA-A2 allele

CSIR-IMTECH

FDR4

This server predicts the binding core and binding affinity of peptides binding to HLA-DRB1*0401 allele

CSIR-IMTECH

FungalRV

Adhesin Prediction and Immunoinformatics portal for human fungal pathogens

CSIR-IGIB

MalVac

 Database of Malarial Vaccine Candidates

CSIR-IGIB

MAAP

MAAP is a web server that is used for prediction of Malarial adhesins and adhesins-like proteins.

CSIR-IGIB


Please contact salmanusmani@imtech.res.in for any changes or suggestions.