| Primary information |
|---|
| AHTPDB ID | 1954 |
| PMID | 19524628 |
| YEAR | 2010 |
| SEQUENCE | AVF |
| LENGTH | 3 |
| MOL WT | 335.4 |
| IC50 | ND |
| pIC50 | ND |
| SOURCE | Insect protein |
| TESTED ON | SHR |
| PURIFICATION | SEC, RP-HPLC |
| ASSAY | Cushman and Cheung (1971) |
| BITTERNESS | ND |
| ISOELECTRIC POINT | 5.57 |
| SYSTOLIC BP DECREASE | 10 |
| Secondary information |
|---|
| Properties | Physico-Chemical details |
| STRUCTURE | |
| DSSP states | CCC |
| SMILES | N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O |
| External Links to PDB, Swiss-Prot and IEDB |
|---|
| PDB exact | PDB partial | SP exact | SP partial | IEDB exact | IEDB partial |
| NA |
NA |
NA |
B9E1X0
from
342
TO
344 |
NA |
1527
from
6
TO
8 |
|
| Reference Informaiton |
|---|
| ARTICLE/REFERENCE | Ala-Val-Phe and Val-Phe: ACE inhibitory peptides derived from insect protein with antihypertensive activity in spontaneously hypertensive rats. |
| AUTHORS/PRIMARY REFERENCE | Vercruysse L1, Van Camp J, Morel N, Rougé P, Herregods G, Smagghe G. |
| JOURNAL/EXTRA LINKS | Peptides. 2010 Mar;31(3):482-8. |