| Primary information |
|---|
| AHTPDB ID | 4190 |
| PMID | 20397194 |
| YEAR | 2010 |
| SEQUENCE | HPHPHLSF |
| LENGTH | 8 |
| MOL WT | 970.5 |
| IC50 | 28.9 mM |
| pIC50 | ND |
| SOURCE | Milk Casein derived |
| TESTED ON | SHR |
| PURIFICATION | Spectrophotometric, HPLC, UPLC |
| ASSAY | Cushman and Cheung (1971) |
| BITTERNESS | ND |
| ISOELECTRIC POINT | 7.02 |
| SYSTOLIC BP DECREASE | 15.7 |
| Secondary information |
|---|
| Properties | Physico-Chemical details |
| STRUCTURE | |
| DSSP states | CCCCSCCC |
| SMILES | N[C@@H](Cc1[nH]cnc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)O |
| External Links to PDB, Swiss-Prot and IEDB |
|---|
| PDB exact | PDB partial | SP exact | SP partial | IEDB exact | IEDB partial |
| NA |
NA |
NA |
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| Reference Informaiton |
|---|
| ARTICLE/REFERENCE | Changes in arterial blood pressure after single oral administration of milk-casein-derived peptides in spontaneously hypertensive rats |
| AUTHORS/PRIMARY REFERENCE | Marta Miguel et al., |
| JOURNAL/EXTRA LINKS | Mol. Nutr. Food Res., 2010, 54, 1422–1427. |