AHTpin: Designing of Antihypetensive peptides

AHTpin

Antihypertensive Peptide Inhibitors


Updated version at IIIT Delhi

*** Reference: Kumar et. al. (2015) An in silico platform for predicting, screening and designing of antihypertensive peptides. Sci. Rep. 5, 12512.

Updated version at IIIT Delhi

Propensity Matrices page of AHTpin

Propensity Matrices of AHTPs
(Lengthwise Distribution)

Select the Propensity Matrix to be displayed
Di PM Tri PM Tetra PM Penta PM
Hexa PM 7-12 PM >12 PM All PM
        
Color Notation for PM Score
Below -16  
-16 to -14  
-14 to -12  
-12 to -10  
-10 to -8  
-8 to -6  
-6 to -4  
-4 to -2  
-2 to 0  
2 to 0  
4 to 2  
6 to 4  
8 to 6  
10 to 8  
12 to 10  
14 to 12  
16 to 14  
Above 16  
PM for Hexa AHTs
Graphical Representation
Res 1 2 3 4 5 6
A -1.00 0.00 -1.01 -5.03 -1.01 2.01
C 1.01 -0.50 -2.01 -1.01 0.50 0.50
D -5.02 -6.54 -2.52 -2.01 -0.50 -4.02
E -3.52 -4.02 -3.02 -3.52 -4.02 -3.52
F -0.50 -1.00 -2.52 -1.01 -0.51 5.03
G -0.50 -3.01 0.51 -1.01 -3.02 -4.52
H 0.50 6.03 5.52 -0.50 0.00 -0.51
I -3.52 1.01 -6.03 8.54 -1.01 -5.53
K 3.51 -1.01 -2.01 -2.01 -3.51 -5.52
L 2.51 0.00 6.03 -3.51 4.02 -1.00
M -1.50 0.00 -2.01 -3.52 -1.00 0.51
N -2.01 -1.51 -2.01 -0.50 -2.01 0.00
P 6.53 9.04 14.07 22.11 15.07 16.58
Q -2.01 0.50 0.50 3.52 2.01 0.00
R -0.50 -6.03 -1.51 -2.01 -2.01 0.50
S -4.02 -0.50 -4.02 -6.54 -2.01 -6.03
T -4.52 3.02 0.00 -3.52 -3.02 -5.53
V 8.04 0.50 0.50 2.51 0.50 -3.51
W 0.00 1.51 0.51 1.00 -3.01 8.04
Y 6.54 2.51 1.00 -2.01 4.52 6.53