Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              18    1135
XP_005262424                                                           18    1135
NP_001269852                                                           16    5631
NP_060260                                                              16    5631
NP_001263190                                                           16    5631
NP_652759                                                              16    5631
NP_570613                                                              16    5631
NP_060143                                                              16    5631
XP_006717286                                                           16    5631
XP_006717285                                                           16    5631
XP_006717284                                                           16    5631
XP_006717283                                                           16    5631
XP_006717282                                                           16    5631
XP_006711455                                                           16    5631
XP_006711454                                                           16    5631
XP_005245330                                                           16    5631
XP_005245328                                                           16    5631
NP_001098988                                                           16    5631
NP_001157472                                                           16    7355
NP_001098547                                                           16    7355
NP_001157471                                                           16    7355
NP_005232                                                              16    7355
NP_001192123                                                           16    7355
NP_004982                                                              16    7355
NP_001098548                                                           16    7355
XP_006726589                                                           16    7355
XP_006718462                                                           16    7355
XP_005247283                                                           16    7355
XP_005247282                                                           16    7355
XP_005247281                                                           16    7355
XP_005247280                                                           16    7355
XP_005247278                                                           16    7355
XP_005247276                                                           16    7355
XP_005247277                                                           16    7355
XP_006713599                                                           16    7355
XP_005247273                                                           16    7355
XP_005247272                                                           16    7355
XP_005247271                                                           16    7355
XP_005247270                                                           16    7355
XP_006710010                                                           16    7355
NP_001185744                                                           15    9605
NP_775808                                                              15    9605
XP_005275558                                                           15    9605
XP_005275391                                                           15    9605
XP_005275259                                                           15    9605
XP_005274965                                                           15    9605
XP_005272815                                                           15    9605
XP_005274885                                                           15    9605
XP_005277669                                                           15    9605
XP_005277638                                                           15    9605
XP_005277637                                                           15    9605
XP_005277636                                                           15    9605
XP_005248836                                                           15    9605
NP_001003795                                                           15    9605
>NP_722576
          Length = 3080

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AEITLFSTS 9
            AE TLFSTS
Sbjct: 1124 AETTLFSTS 1132
>XP_005262424
          Length = 2875

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AEITLFSTS 9
           AE TLFSTS
Sbjct: 919 AETTLFSTS 927
>NP_001269852
          Length = 1088

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEITLFSTS 9
           AE+TLF+ S
Sbjct: 475 AEVTLFAYS 483
>NP_060260
          Length = 602

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEITLFSTS 9
           AE+TLF+ S
Sbjct: 473 AEVTLFAYS 481
>NP_001263190
          Length = 591

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEITLFSTS 9
           AE+TLF+ S
Sbjct: 304 AEVTLFAYS 312
>NP_652759
          Length = 1198

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEITLFSTS 9
           AE+TLF+ S
Sbjct: 585 AEVTLFAYS 593
>NP_570613
          Length = 917

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEITLFSTS 9
           AE+TLF+ S
Sbjct: 304 AEVTLFAYS 312
>NP_060143
          Length = 900

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EITLFSTS 9
           EIT+FS+S
Sbjct: 737 EITVFSSS 744
>XP_006717286
          Length = 610

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEITLFSTS 9
           AE+TLF+ S
Sbjct: 481 AEVTLFAYS 489
>XP_006717285
          Length = 824

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEITLFSTS 9
           AE+TLF+ S
Sbjct: 211 AEVTLFAYS 219
>XP_006717284
          Length = 961

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEITLFSTS 9
           AE+TLF+ S
Sbjct: 348 AEVTLFAYS 356
>XP_006717283
          Length = 1086

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEITLFSTS 9
           AE+TLF+ S
Sbjct: 473 AEVTLFAYS 481
>XP_006717282
          Length = 1094

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEITLFSTS 9
           AE+TLF+ S
Sbjct: 481 AEVTLFAYS 489
>XP_006711455
          Length = 907

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EITLFSTS 9
           EIT+FS+S
Sbjct: 744 EITVFSSS 751
>XP_006711454
          Length = 907

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EITLFSTS 9
           EIT+FS+S
Sbjct: 744 EITVFSSS 751
>XP_005245330
          Length = 907

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EITLFSTS 9
           EIT+FS+S
Sbjct: 744 EITVFSSS 751
>XP_005245328
          Length = 907

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EITLFSTS 9
           EIT+FS+S
Sbjct: 744 EITVFSSS 751
>NP_001098988
          Length = 900

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EITLFSTS 9
           EIT+FS+S
Sbjct: 737 EITVFSSS 744
>NP_001157472
          Length = 1042

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEITLFSTS 9
           AE++ FSTS
Sbjct: 973 AELSSFSTS 981
>NP_001098547
          Length = 1116

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AEITLFSTS 9
            AE++ FSTS
Sbjct: 1047 AELSSFSTS 1055
>NP_001157471
          Length = 1043

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEITLFSTS 9
           AE++ FSTS
Sbjct: 974 AELSSFSTS 982
>NP_005232
          Length = 1051

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEITLFSTS 9
           AE++ FSTS
Sbjct: 982 AELSSFSTS 990
>NP_001192123
          Length = 1051

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEITLFSTS 9
           AE++ FSTS
Sbjct: 982 AELSSFSTS 990
>NP_004982
          Length = 1239

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AEITLFSTS 9
            AE++ FSTS
Sbjct: 1170 AELSSFSTS 1178
>NP_001098548
          Length = 1051

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEITLFSTS 9
           AE++ FSTS
Sbjct: 982 AELSSFSTS 990
>XP_006726589
          Length = 931

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ITLFSTS 9
           +TLFSTS
Sbjct: 537 MTLFSTS 543
>XP_006718462
          Length = 4966

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    ITLFSTS 9
            +TLFSTS
Sbjct: 4572 MTLFSTS 4578
>XP_005247283
          Length = 906

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEITLFSTS 9
           AE++ FSTS
Sbjct: 837 AELSSFSTS 845
>XP_005247282
          Length = 915

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEITLFSTS 9
           AE++ FSTS
Sbjct: 846 AELSSFSTS 854
>XP_005247281
          Length = 916

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEITLFSTS 9
           AE++ FSTS
Sbjct: 847 AELSSFSTS 855
>XP_005247280
          Length = 1051

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEITLFSTS 9
           AE++ FSTS
Sbjct: 982 AELSSFSTS 990
>XP_005247278
          Length = 1052

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEITLFSTS 9
           AE++ FSTS
Sbjct: 983 AELSSFSTS 991
>XP_005247276
          Length = 1052

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEITLFSTS 9
           AE++ FSTS
Sbjct: 983 AELSSFSTS 991
>XP_005247277
          Length = 1052

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEITLFSTS 9
           AE++ FSTS
Sbjct: 983 AELSSFSTS 991
>XP_006713599
          Length = 1116

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AEITLFSTS 9
            AE++ FSTS
Sbjct: 1047 AELSSFSTS 1055
>XP_005247273
          Length = 1212

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AEITLFSTS 9
            AE++ FSTS
Sbjct: 1143 AELSSFSTS 1151
>XP_005247272
          Length = 1230

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AEITLFSTS 9
            AE++ FSTS
Sbjct: 1161 AELSSFSTS 1169
>XP_005247271
          Length = 1231

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AEITLFSTS 9
            AE++ FSTS
Sbjct: 1162 AELSSFSTS 1170
>XP_005247270
          Length = 1240

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AEITLFSTS 9
            AE++ FSTS
Sbjct: 1171 AELSSFSTS 1179
>XP_006710010
          Length = 1103

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ITLFSTS 9
           +TLFSTS
Sbjct: 709 MTLFSTS 715
>NP_001185744
          Length = 1773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEITLFSTS 9
           +EIT+ STS
Sbjct: 693 SEITIASTS 701
>NP_775808
          Length = 949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AEITLFST 8
           +E+TLFS+
Sbjct: 845 SELTLFSS 852
>XP_005275558
          Length = 1776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEITLFSTS 9
           +EIT+ STS
Sbjct: 696 SEITIASTS 704
>XP_005275391
          Length = 1776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEITLFSTS 9
           +EIT+ STS
Sbjct: 696 SEITIASTS 704
>XP_005275259
          Length = 1776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEITLFSTS 9
           +EIT+ STS
Sbjct: 696 SEITIASTS 704
>XP_005274965
          Length = 1776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEITLFSTS 9
           +EIT+ STS
Sbjct: 696 SEITIASTS 704
>XP_005272815
          Length = 1776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEITLFSTS 9
           +EIT+ STS
Sbjct: 696 SEITIASTS 704
>XP_005274885
          Length = 1776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEITLFSTS 9
           +EIT+ STS
Sbjct: 696 SEITIASTS 704
>XP_005277669
          Length = 949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AEITLFST 8
           +E+TLFS+
Sbjct: 845 SELTLFSS 852
>XP_005277638
          Length = 755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AEITLFST 8
           +E+TLFS+
Sbjct: 651 SELTLFSS 658
>XP_005277637
          Length = 878

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AEITLFST 8
           +E+TLFS+
Sbjct: 774 SELTLFSS 781
>XP_005277636
          Length = 949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AEITLFST 8
           +E+TLFS+
Sbjct: 845 SELTLFSS 852
>XP_005248836
          Length = 1776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEITLFSTS 9
           +EIT+ STS
Sbjct: 696 SEITIASTS 704
>NP_001003795
          Length = 949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AEITLFST 8
           +E+TLFS+
Sbjct: 845 SELTLFSS 852
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.311    0.118    0.277 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 345,596
Number of extensions: 347
Number of successful extensions: 54
Number of sequences better than 10000.0: 54
Number of HSP's gapped: 54
Number of HSP's successfully gapped: 54
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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