Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results 
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done




                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004295                                                              18    1482
NP_001769                                                              16    5631
NP_001242959                                                           16    5631
XP_005245682                                                           16    5631
NP_071741                                                              16    7355
NP_056453                                                              16    7355
NP_955400                                                              16    7355
NP_612354                                                              16    7355
XP_006714035                                                           16    7355
XP_006714034                                                           16    7355
XP_006713882                                                           16    7355
XP_006713881                                                           16    7355
NP_054706                                                              15    9605
XP_005270199                                                           15    9605
XP_005263223                                                           15    9605



>NP_004295
          Length = 1620

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AIEILLMPT 9
           A EILLMPT
Sbjct: 372 AREILLMPT 380





>NP_001769
          Length = 243

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  AIEILLMP 8
          A+E+LL+P
Sbjct: 11 ALELLLLP 18





>NP_001242959
          Length = 252

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  AIEILLMP 8
          A+E+LL+P
Sbjct: 11 ALELLLLP 18





>XP_005245682
          Length = 154

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  AIEILLMP 8
          A+E+LL+P
Sbjct: 11 ALELLLLP 18





>NP_071741
          Length = 1015

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EILLMPT 9
           EIL++PT
Sbjct: 429 EILILPT 435





>NP_056453
          Length = 797

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IEILLMPT 9
           +EIL+ PT
Sbjct: 141 VEILMRPT 148





>NP_955400
          Length = 789

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IEILLMPT 9
           +EIL+ PT
Sbjct: 141 VEILMRPT 148





>NP_612354
          Length = 1242

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AIEILLMPT 9
           A+EILL P+
Sbjct: 265 ALEILLHPS 273





>XP_006714035
          Length = 941

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EILLMPT 9
           EIL++PT
Sbjct: 429 EILILPT 435





>XP_006714034
          Length = 941

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EILLMPT 9
           EIL++PT
Sbjct: 429 EILILPT 435





>XP_006713882
          Length = 1242

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AIEILLMPT 9
           A+EILL P+
Sbjct: 265 ALEILLHPS 273





>XP_006713881
          Length = 1024

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  AIEILLMPT 9
          A+EILL P+
Sbjct: 46 ALEILLHPS 54





>NP_054706
          Length = 1134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EILLMPT 9
           E+LLMP+
Sbjct: 952 ELLLMPS 958





>XP_005270199
          Length = 1135

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EILLMPT 9
           E+LLMP+
Sbjct: 953 ELLLMPS 959





>XP_005263223
          Length = 314

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IEILLMPT 9
           I +LL+PT
Sbjct: 307 ISVLLIPT 314





  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.330    0.145    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 495,421
Number of extensions: 774
Number of successful extensions: 15
Number of sequences better than 10000.0: 15
Number of HSP's gapped: 15
Number of HSP's successfully gapped: 15
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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