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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              19     665
NP_001075109                                                           19     665
XP_006720120                                                           17    4312
XP_006720119                                                           17    4312
NP_689659                                                              17    4312
NP_008949                                                              16    7355
XP_006717006                                                           16    7355
XP_006717005                                                           16    7355
XP_006717004                                                           16    7355
XP_006717003                                                           16    7355
XP_005251736                                                           16    7355
NP_079390                                                              15    9605
NP_055497                                                              15    9605
NP_005024                                                              15    9605
NP_079490                                                              15    9605
NP_001137301                                                           15    9605
NP_005081                                                              15    9605
NP_001029366                                                           15    9605
NP_061748                                                              15    9605
NP_115270                                                              15    9605
NP_001185517                                                           15    9605
XP_005266829                                                           15    9605
XP_006722615                                                           15    9605
XP_006719673                                                           15    9605
XP_005269218                                                           15    9605
XP_005269217                                                           15    9605
XP_006719672                                                           15    9605
XP_005269215                                                           15    9605
XP_006716553                                                           15    9605
XP_006716552                                                           15    9605
XP_006716551                                                           15    9605
XP_006716550                                                           15    9605
NP_001108105                                                           15    9605

>NP_008835
          Length = 4128

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ELKTQVTSA 9
           ELKTQ+TSA
Sbjct: 203 ELKTQMTSA 211



>NP_001075109
          Length = 4097

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ELKTQVTSA 9
           ELKTQ+TSA
Sbjct: 203 ELKTQMTSA 211



>XP_006720120
          Length = 1055

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ELKTQVTSA 9
           EL+TQ+T A
Sbjct: 272 ELRTQLTKA 280




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ELKTQVTSA 9
           ELKTQ+ +A
Sbjct: 488 ELKTQLYAA 496



>XP_006720119
          Length = 1094

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ELKTQVTSA 9
           EL+TQ+T A
Sbjct: 311 ELRTQLTKA 319




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ELKTQVTSA 9
           ELKTQ+ +A
Sbjct: 527 ELKTQLYAA 535



>NP_689659
          Length = 1094

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ELKTQVTSA 9
           EL+TQ+T A
Sbjct: 311 ELRTQLTKA 319




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ELKTQVTSA 9
           ELKTQ+ +A
Sbjct: 527 ELKTQLYAA 535



>NP_008949
          Length = 2325

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ELKTQVTS 8
            +LK+QVTS
Sbjct: 1584 KLKSQVTS 1591



>XP_006717006
          Length = 1760

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ELKTQVTS 8
            +LK+QVTS
Sbjct: 1004 KLKSQVTS 1011



>XP_006717005
          Length = 1788

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ELKTQVTS 8
            +LK+QVTS
Sbjct: 1032 KLKSQVTS 1039



>XP_006717004
          Length = 2240

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ELKTQVTS 8
            +LK+QVTS
Sbjct: 1584 KLKSQVTS 1591



>XP_006717003
          Length = 2278

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ELKTQVTS 8
            +LK+QVTS
Sbjct: 1584 KLKSQVTS 1591



>XP_005251736
          Length = 2325

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ELKTQVTS 8
            +LK+QVTS
Sbjct: 1584 KLKSQVTS 1591



>NP_079390
          Length = 2479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    ELKTQV 6
            ELKTQV
Sbjct: 1786 ELKTQV 1791



>NP_055497
          Length = 1047

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ELKTQVTS 8
           +L+TQ+TS
Sbjct: 949 KLQTQITS 956



>NP_005024
          Length = 439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELKTQVTSA 9
           +++TQ TSA
Sbjct: 410 KIRTQTTSA 418



>NP_079490
          Length = 335

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ELKTQV 6
           ELKTQV
Sbjct: 294 ELKTQV 299



>NP_001137301
          Length = 335

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ELKTQV 6
           ELKTQV
Sbjct: 294 ELKTQV 299



>NP_005081
          Length = 1012

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LKTQVT 7
           LKTQVT
Sbjct: 593 LKTQVT 598



>NP_001029366
          Length = 456

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELKTQVTSA 9
           +++TQ TSA
Sbjct: 427 KIRTQTTSA 435



>NP_061748
          Length = 923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ELKTQVTSA 9
           EL+ QVT A
Sbjct: 227 ELRIQVTDA 235



>NP_115270
          Length = 818

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ELKTQVTSA 9
           EL+ QVT A
Sbjct: 227 ELRIQVTDA 235



>NP_001185517
          Length = 893

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LKTQVT 7
           LKTQVT
Sbjct: 593 LKTQVT 598



>XP_005266829
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ELKTQV 6
           ELKTQV
Sbjct: 247 ELKTQV 252



>XP_006722615
          Length = 335

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ELKTQV 6
           ELKTQV
Sbjct: 294 ELKTQV 299



>XP_006719673
          Length = 1997

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    ELKTQV 6
            ELKTQV
Sbjct: 1304 ELKTQV 1309



>XP_005269218
          Length = 2009

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    ELKTQV 6
            ELKTQV
Sbjct: 1316 ELKTQV 1321



>XP_005269217
          Length = 2353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    ELKTQV 6
            ELKTQV
Sbjct: 1817 ELKTQV 1822



>XP_006719672
          Length = 2510

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    ELKTQV 6
            ELKTQV
Sbjct: 1817 ELKTQV 1822



>XP_005269215
          Length = 2510

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    ELKTQV 6
            ELKTQV
Sbjct: 1817 ELKTQV 1822



>XP_006716553
          Length = 965

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ELKTQVTS 8
           +L+TQ+TS
Sbjct: 867 KLQTQITS 874



>XP_006716552
          Length = 1038

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ELKTQVTS 8
           +L+TQ+TS
Sbjct: 949 KLQTQITS 956



>XP_006716551
          Length = 1047

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ELKTQVTS 8
           +L+TQ+TS
Sbjct: 949 KLQTQITS 956



>XP_006716550
          Length = 1047

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ELKTQVTS 8
           +L+TQ+TS
Sbjct: 949 KLQTQITS 956



>NP_001108105
          Length = 781

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LKTQVT 7
           LKTQVT
Sbjct: 362 LKTQVT 367



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.292    0.103    0.224 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 319,461
Number of extensions: 450
Number of successful extensions: 36
Number of sequences better than 10000.0: 33
Number of HSP's gapped: 36
Number of HSP's successfully gapped: 36
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)