Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              21     229
XP_005262424                                                           21     229
NP_001714                                                              17    2528
NP_001041445                                                           17    2528
XP_005249383                                                           17    2528
NP_001127848                                                           17    3301
NP_001127847                                                           17    3301
NP_061957                                                              17    3301
XP_005269978                                                           17    3301
NP_001018048                                                           17    4312
NP_056001                                                              17    4312
NP_001018047                                                           17    4312
NP_150648                                                              17    4312
XP_005263742                                                           17    4312
XP_005263740                                                           17    4312
XP_005263739                                                           17    4312
XP_005263738                                                           17    4312
NP_055178                                                              16    5631
NP_001264984                                                           16    5631
XP_005266395                                                           16    5631
NP_008877                                                              16    7355
NP_001269961                                                           16    7355
NP_001269960                                                           16    7355
NP_003119                                                              16    7355
NP_001269962                                                           16    7355
NP_057190                                                              16    7355
NP_878255                                                              16    7355
NP_001244305                                                           16    7355
XP_005267526                                                           16    7355
XP_005274250                                                           16    7355
XP_006718734                                                           16    7355
XP_006718733                                                           16    7355
XP_005274249                                                           16    7355
XP_006718732                                                           16    7355
XP_006713658                                                           16    7355
XP_005264575                                                           16    7355
XP_006712150                                                           16    7355
XP_005264574                                                           16    7355
NP_842565                                                              16    7355
NP_149017                                                              15    9605
NP_001106962                                                           15    9605
NP_063968                                                              15    9605
NP_001112                                                              15    9605
NP_058432                                                              15    9605
XP_005262146                                                           15    9605
XP_005262145                                                           15    9605
XP_005262144                                                           15    9605
XP_006720688                                                           15    9605
XP_006720687                                                           15    9605
XP_006720686                                                           15    9605
XP_005269592                                                           15    9605
XP_006717692                                                           15    9605
XP_006717691                                                           15    9605
XP_005269591                                                           15    9605
XP_006717690                                                           15    9605
XP_005269590                                                           15    9605
XP_006717689                                                           15    9605
XP_005269588                                                           15    9605
XP_005269587                                                           15    9605
XP_005269586                                                           15    9605
>NP_722576
          Length = 3080

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    INIVLEKQN 9
            IN+VLEKQN
Sbjct: 2518 INVVLEKQN 2526
>XP_005262424
          Length = 2875

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    INIVLEKQN 9
            IN+VLEKQN
Sbjct: 2313 INVVLEKQN 2321
>NP_001714
          Length = 2649

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2    NIVLEKQ 8
            NIVLEKQ
Sbjct: 1599 NIVLEKQ 1605
>NP_001041445
          Length = 421

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   INIVLEKQN 9
           +NI+LE QN
Sbjct: 275 LNILLENQN 283
>XP_005249383
          Length = 3186

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2    NIVLEKQ 8
            NIVLEKQ
Sbjct: 2136 NIVLEKQ 2142
>NP_001127848
          Length = 371

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   INIVLEKQN 9
           +N+VL KQN
Sbjct: 118 MNLVLTKQN 126
>NP_001127847
          Length = 383

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   INIVLEKQN 9
           +N+VL KQN
Sbjct: 118 MNLVLTKQN 126
>NP_061957
          Length = 372

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   INIVLEKQN 9
           +N+VL KQN
Sbjct: 118 MNLVLTKQN 126
>XP_005269978
          Length = 269

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  INIVLEKQN 9
          +N+VL KQN
Sbjct: 4  MNLVLTKQN 12
>NP_001018048
          Length = 3069

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    INIVLEKQN 9
            INIV EK N
Sbjct: 2079 INIVPEKDN 2087
>NP_056001
          Length = 3095

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    INIVLEKQN 9
            INIV EK N
Sbjct: 2079 INIVPEKDN 2087
>NP_001018047
          Length = 3135

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    INIVLEKQN 9
            INIV EK N
Sbjct: 2040 INIVPEKDN 2048
>NP_150648
          Length = 3174

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    INIVLEKQN 9
            INIV EK N
Sbjct: 2079 INIVPEKDN 2087
>XP_005263742
          Length = 1043

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   NIVLEKQN 9
           +IVLEK+N
Sbjct: 922 SIVLEKEN 929
>XP_005263740
          Length = 1441

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   NIVLEKQN 9
           +IVLEK+N
Sbjct: 922 SIVLEKEN 929
>XP_005263739
          Length = 1839

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   NIVLEKQN 9
           +IVLEK+N
Sbjct: 922 SIVLEKEN 929
>XP_005263738
          Length = 1876

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   NIVLEKQN 9
           +IVLEK+N
Sbjct: 922 SIVLEKEN 929
>NP_055178
          Length = 4579

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   INIVLEKQN 9
           +NIVLE+++
Sbjct: 375 VNIVLEEES 383
>NP_001264984
          Length = 4432

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   INIVLEKQN 9
           +NIVLE+++
Sbjct: 228 VNIVLEEES 236
>XP_005266395
          Length = 4588

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   INIVLEKQN 9
           +NIVLE+++
Sbjct: 375 VNIVLEEES 383
>NP_008877
          Length = 2390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    INIVLEKQ 8
            +NI+L+KQ
Sbjct: 1418 VNILLKKQ 1425
>NP_001269961
          Length = 583

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NIVLEKQN 9
           N+VL++QN
Sbjct: 478 NLVLKQQN 485
>NP_001269960
          Length = 457

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NIVLEKQN 9
           N+VL++QN
Sbjct: 352 NLVLKQQN 359
>NP_003119
          Length = 2364

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    INIVLEKQ 8
            +NI+L+KQ
Sbjct: 1415 VNILLKKQ 1422
>NP_001269962
          Length = 457

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NIVLEKQN 9
           N+VL++QN
Sbjct: 352 NLVLKQQN 359
>NP_057190
          Length = 642

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NIVLEKQN 9
           N+VL++QN
Sbjct: 537 NLVLKQQN 544
>NP_878255
          Length = 575

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NIVLEKQN 9
           N+VL++QN
Sbjct: 470 NLVLKQQN 477
>NP_001244305
          Length = 550

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NIVLEKQN 9
           N+VL++QN
Sbjct: 445 NLVLKQQN 452
>XP_005267526
          Length = 617

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NIVLEKQN 9
           N+VL++QN
Sbjct: 512 NLVLKQQN 519
>XP_005274250
          Length = 2390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    INIVLEKQ 8
            +NI+L+KQ
Sbjct: 1418 VNILLKKQ 1425
>XP_006718734
          Length = 2390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    INIVLEKQ 8
            +NI+L+KQ
Sbjct: 1418 VNILLKKQ 1425
>XP_006718733
          Length = 2390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    INIVLEKQ 8
            +NI+L+KQ
Sbjct: 1418 VNILLKKQ 1425
>XP_005274249
          Length = 2390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    INIVLEKQ 8
            +NI+L+KQ
Sbjct: 1418 VNILLKKQ 1425
>XP_006718732
          Length = 2397

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    INIVLEKQ 8
            +NI+L+KQ
Sbjct: 1425 VNILLKKQ 1432
>XP_006713658
          Length = 212

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   INIVLEKQ 8
           IN+V+EK+
Sbjct: 176 INLVIEKR 183
>XP_005264575
          Length = 2351

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    INIVLEKQ 8
            +NI+L+KQ
Sbjct: 1402 VNILLKKQ 1409
>XP_006712150
          Length = 2364

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    INIVLEKQ 8
            +NI+L+KQ
Sbjct: 1415 VNILLKKQ 1422
>XP_005264574
          Length = 2364

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    INIVLEKQ 8
            +NI+L+KQ
Sbjct: 1415 VNILLKKQ 1422
>NP_842565
          Length = 2155

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    INIVLEKQ 8
            +NI+L+KQ
Sbjct: 1402 VNILLKKQ 1409
>NP_149017
          Length = 519

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  VLEKQN 9
          +LEKQN
Sbjct: 31 ILEKQN 36
>NP_001106962
          Length = 1084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2  NIVLEKQ 8
          N+++EKQ
Sbjct: 89 NLIMEKQ 95
>NP_063968
          Length = 674

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NIVLEKQN 9
           N VLEK+N
Sbjct: 499 NEVLEKRN 506
>NP_001112
          Length = 674

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NIVLEKQN 9
           N VLEK+N
Sbjct: 499 NEVLEKRN 506
>NP_058432
          Length = 706

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NIVLEKQN 9
           N VLEK+N
Sbjct: 499 NEVLEKRN 506
>XP_005262146
          Length = 1084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2  NIVLEKQ 8
          N+++EKQ
Sbjct: 89 NLIMEKQ 95
>XP_005262145
          Length = 1084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2  NIVLEKQ 8
          N+++EKQ
Sbjct: 89 NLIMEKQ 95
>XP_005262144
          Length = 1084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2  NIVLEKQ 8
          N+++EKQ
Sbjct: 89 NLIMEKQ 95
>XP_006720688
          Length = 496

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  VLEKQN 9
          +LEKQN
Sbjct: 31 ILEKQN 36
>XP_006720687
          Length = 504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  VLEKQN 9
          +LEKQN
Sbjct: 39 ILEKQN 44
>XP_006720686
          Length = 507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  VLEKQN 9
          +LEKQN
Sbjct: 19 ILEKQN 24
>XP_005269592
          Length = 628

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NIVLEKQN 9
           N VLEK+N
Sbjct: 421 NEVLEKRN 428
>XP_006717692
          Length = 628

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NIVLEKQN 9
           N VLEK+N
Sbjct: 421 NEVLEKRN 428
>XP_006717691
          Length = 706

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NIVLEKQN 9
           N VLEK+N
Sbjct: 499 NEVLEKRN 506
>XP_005269591
          Length = 706

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NIVLEKQN 9
           N VLEK+N
Sbjct: 499 NEVLEKRN 506
>XP_006717690
          Length = 706

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NIVLEKQN 9
           N VLEK+N
Sbjct: 499 NEVLEKRN 506
>XP_005269590
          Length = 706

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NIVLEKQN 9
           N VLEK+N
Sbjct: 499 NEVLEKRN 506
>XP_006717689
          Length = 706

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NIVLEKQN 9
           N VLEK+N
Sbjct: 499 NEVLEKRN 506
>XP_005269588
          Length = 706

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NIVLEKQN 9
           N VLEK+N
Sbjct: 499 NEVLEKRN 506
>XP_005269587
          Length = 706

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NIVLEKQN 9
           N VLEK+N
Sbjct: 499 NEVLEKRN 506
>XP_005269586
          Length = 706

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NIVLEKQN 9
           N VLEK+N
Sbjct: 499 NEVLEKRN 506
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.136    0.329 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 535,025
Number of extensions: 940
Number of successful extensions: 60
Number of sequences better than 10000.0: 60
Number of HSP's gapped: 60
Number of HSP's successfully gapped: 60
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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