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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_079216                                                              18    1935
XP_005273708                                                           18    1935
XP_006716465                                                           18    1935
XP_005273707                                                           18    1935
NP_005091                                                              17    3301
NP_653080                                                              17    3301
NP_055625                                                              17    3301
XP_005267292                                                           17    3301
XP_005267291                                                           17    3301
XP_005267290                                                           17    3301
XP_006711734                                                           17    3301
XP_006711733                                                           17    3301
XP_006711732                                                           17    3301
XP_006711731                                                           17    3301
XP_006711730                                                           17    3301
XP_006711729                                                           17    3301
XP_005245695                                                           17    3301
NP_055935                                                              16    5631
NP_004710                                                              16    7355
NP_068838                                                              16    7355
NP_061756                                                              16    7355
XP_005262246                                                           16    7355
XP_005262245                                                           16    7355
XP_005262244                                                           16    7355
XP_006724750                                                           16    7355
XP_005262243                                                           16    7355
XP_006719755                                                           16    7355
XP_005269287                                                           16    7355
NP_061993                                                              16    7355
NP_004251                                                              15    9605

>NP_079216
          Length = 1870

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   KVSVAIEE 8
           KVS+AIEE
Sbjct: 514 KVSIAIEE 521



>XP_005273708
          Length = 1032

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   KVSVAIEE 8
           KVS+AIEE
Sbjct: 228 KVSIAIEE 235



>XP_006716465
          Length = 1826

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   KVSVAIEE 8
           KVS+AIEE
Sbjct: 514 KVSIAIEE 521



>XP_005273707
          Length = 1847

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   KVSVAIEE 8
           KVS+AIEE
Sbjct: 514 KVSIAIEE 521



>NP_005091
          Length = 1782

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    KVSVAIEE 8
            KVSVAIE+
Sbjct: 1525 KVSVAIED 1532



>NP_653080
          Length = 1684

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    KVSVAIEE 8
            KVSVAIE+
Sbjct: 1427 KVSVAIED 1434



>NP_055625
          Length = 3117

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KVSVAIEED 9
            KVS+A E+D
Sbjct: 2676 KVSIAAEDD 2684



>XP_005267292
          Length = 1677

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    KVSVAIEE 8
            KVSVAIE+
Sbjct: 1420 KVSVAIED 1427



>XP_005267291
          Length = 1684

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    KVSVAIEE 8
            KVSVAIE+
Sbjct: 1427 KVSVAIED 1434



>XP_005267290
          Length = 1782

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    KVSVAIEE 8
            KVSVAIE+
Sbjct: 1525 KVSVAIED 1532



>XP_006711734
          Length = 3136

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KVSVAIEED 9
            KVS+A E+D
Sbjct: 2695 KVSIAAEDD 2703



>XP_006711733
          Length = 3137

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KVSVAIEED 9
            KVS+A E+D
Sbjct: 2696 KVSIAAEDD 2704



>XP_006711732
          Length = 3154

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KVSVAIEED 9
            KVS+A E+D
Sbjct: 2713 KVSIAAEDD 2721



>XP_006711731
          Length = 3157

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KVSVAIEED 9
            KVS+A E+D
Sbjct: 2716 KVSIAAEDD 2724



>XP_006711730
          Length = 3157

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KVSVAIEED 9
            KVS+A E+D
Sbjct: 2716 KVSIAAEDD 2724



>XP_006711729
          Length = 3158

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KVSVAIEED 9
            KVS+A E+D
Sbjct: 2717 KVSIAAEDD 2725



>XP_005245695
          Length = 3158

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KVSVAIEED 9
            KVS+A E+D
Sbjct: 2717 KVSIAAEDD 2725



>NP_055935
          Length = 4169

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    KVSVAIEE 8
            KVS+A+EE
Sbjct: 2370 KVSMALEE 2377



>NP_004710
          Length = 1463

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    KVSVAIE 7
            KVSVA+E
Sbjct: 1359 KVSVAVE 1365



>NP_068838
          Length = 761

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KVSVAIEED 9
           +  VAIEED
Sbjct: 95  EADVAIEED 103



>NP_061756
          Length = 798

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KVSVAIEED 9
           K+S +I+ED
Sbjct: 381 KISCSIQED 389



>XP_005262246
          Length = 761

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KVSVAIEED 9
           +  VAIEED
Sbjct: 95  EADVAIEED 103



>XP_005262245
          Length = 807

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KVSVAIEED 9
           +  VAIEED
Sbjct: 95  EADVAIEED 103



>XP_005262244
          Length = 807

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KVSVAIEED 9
           +  VAIEED
Sbjct: 95  EADVAIEED 103



>XP_006724750
          Length = 807

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KVSVAIEED 9
           +  VAIEED
Sbjct: 95  EADVAIEED 103



>XP_005262243
          Length = 807

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KVSVAIEED 9
           +  VAIEED
Sbjct: 95  EADVAIEED 103



>XP_006719755
          Length = 1418

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    KVSVAIE 7
            KVSVA+E
Sbjct: 1314 KVSVAVE 1320



>XP_005269287
          Length = 1527

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    KVSVAIE 7
            KVSVA+E
Sbjct: 1423 KVSVAVE 1429



>NP_061993
          Length = 801

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KVSVAIEED 9
           K+S +I+ED
Sbjct: 381 KISCSIQED 389



>NP_004251
          Length = 1208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SVAIEED 9
           +VA+EED
Sbjct: 291 AVAVEED 297



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.297    0.120    0.270 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 507,334
Number of extensions: 441
Number of successful extensions: 30
Number of sequences better than 10000.0: 30
Number of HSP's gapped: 30
Number of HSP's successfully gapped: 30
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)