Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              19     869
NP_671714                                                              19     869
XP_006715890                                                           19     869
XP_005250160                                                           19     869
XP_005250159                                                           19     869
NP_001242                                                              17    3301
NP_001035148                                                           17    3301
NP_037506                                                              17    4312
NP_001155901                                                           17    4312
NP_663735                                                              17    4312
NP_113611                                                              17    4312
NP_001034965                                                           16    5631
NP_001166217                                                           16    5631
NP_001166216                                                           16    5631
NP_443160                                                              16    5631
NP_006355                                                              16    5631
NP_001003802                                                           16    5631
NP_001003801                                                           16    5631
NP_003069                                                              16    5631
NP_116780                                                              16    5631
XP_005258661                                                           16    5631
XP_005258658                                                           16    5631
XP_005258657                                                           16    5631
XP_005258656                                                           16    5631
XP_005258655                                                           16    5631
XP_005258654                                                           16    5631
XP_006721500                                                           16    5631
XP_005267319                                                           16    5631
XP_006715356                                                           16    5631
XP_006715355                                                           16    5631
NP_006354                                                              16    5631
NP_116781                                                              16    5631
NP_057726                                                              16    7355
NP_694945                                                              16    7355
NP_115515                                                              16    7355
NP_003557                                                              16    7355
XP_005259367                                                           16    7355
XP_006723476                                                           16    7355
XP_006723475                                                           16    7355
XP_005254495                                                           16    7355
XP_006719694                                                           16    7355
NP_001360                                                              15    9605
NP_115560                                                              15    9605
NP_001254711                                                           15    9605
NP_001254712                                                           15    9605
NP_060219                                                              15    9605
NP_079225                                                              15    9605
NP_001002034                                                           15    9605
XP_005261430                                                           15    9605
XP_005259087                                                           15    9605
XP_006723320                                                           15    9605
XP_005259086                                                           15    9605
XP_006723319                                                           15    9605
XP_005259085                                                           15    9605
XP_006718323                                                           15    9605
XP_005253071                                                           15    9605
XP_005253069                                                           15    9605
XP_005253068                                                           15    9605
XP_006718322                                                           15    9605
XP_005253066                                                           15    9605
XP_005248319                                                           15    9605
XP_005248296                                                           15    9605
XP_005248295                                                           15    9605
XP_006714376                                                           15    9605
XP_006714375                                                           15    9605
XP_005271313                                                           15    9605
NP_009208                                                              15    9605
NP_060498                                                              15    9605
>NP_005742
          Length = 3907

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LQDLQQSLV 9
           L+DLQQSLV
Sbjct: 702 LKDLQQSLV 710
>NP_671714
          Length = 3899

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LQDLQQSLV 9
           L+DLQQSLV
Sbjct: 702 LKDLQQSLV 710
>XP_006715890
          Length = 3860

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LQDLQQSLV 9
           L+DLQQSLV
Sbjct: 702 LKDLQQSLV 710
>XP_005250160
          Length = 3939

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LQDLQQSLV 9
           L+DLQQSLV
Sbjct: 702 LKDLQQSLV 710
>XP_005250159
          Length = 3952

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LQDLQQSLV 9
           L+DLQQSLV
Sbjct: 702 LKDLQQSLV 710
>NP_001242
          Length = 354

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LQDLQQSLV 9
           +QDLQQ +V
Sbjct: 228 MQDLQQKVV 236
>NP_001035148
          Length = 327

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LQDLQQSLV 9
           +QDLQQ +V
Sbjct: 201 MQDLQQKVV 209
>NP_037506
          Length = 868

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LQDLQQSL 8
           L+DLQQS+
Sbjct: 706 LKDLQQSI 713
>NP_001155901
          Length = 873

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LQDLQQSL 8
           L+DLQQS+
Sbjct: 711 LKDLQQSI 718
>NP_663735
          Length = 464

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LQDLQQSL 8
           +Q+LQQSL
Sbjct: 187 IQELQQSL 194
>NP_113611
          Length = 464

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LQDLQQSL 8
           +Q+LQQSL
Sbjct: 187 IQELQQSL 194
>NP_001034965
          Length = 404

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQDLQQSL 8
           LQDL+Q L
Sbjct: 120 LQDLEQGL 127
>NP_001166217
          Length = 749

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QDLQQSLV 9
           QDL QSL+
Sbjct: 594 QDLTQSLI 601
>NP_001166216
          Length = 767

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QDLQQSLV 9
           QDL QSL+
Sbjct: 612 QDLTQSLI 619
>NP_443160
          Length = 804

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQDLQQSL 8
           LQDLQQ +
Sbjct: 654 LQDLQQQV 661
>NP_006355
          Length = 765

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QDLQQSLV 9
           QDL QSL+
Sbjct: 610 QDLTQSLI 617
>NP_001003802
          Length = 470

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QDLQQSLV 9
           Q+L+QSLV
Sbjct: 459 QELEQSLV 466
>NP_001003801
          Length = 483

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QDLQQSLV 9
           Q+L+QSLV
Sbjct: 472 QELEQSLV 479
>NP_003069
          Length = 470

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QDLQQSLV 9
           Q+L+QSLV
Sbjct: 459 QELEQSLV 466
>NP_116780
          Length = 767

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QDLQQSLV 9
           QDL QSL+
Sbjct: 612 QDLTQSLI 619
>XP_005258661
          Length = 274

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQDLQQSL 8
           LQDL+Q L
Sbjct: 120 LQDLEQGL 127
>XP_005258658
          Length = 338

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQDLQQSL 8
           LQDL+Q L
Sbjct: 120 LQDLEQGL 127
>XP_005258657
          Length = 341

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LQDLQQSL 8
          LQDL+Q L
Sbjct: 40 LQDLEQGL 47
>XP_005258656
          Length = 356

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQDLQQSL 8
           LQDL+Q L
Sbjct: 120 LQDLEQGL 127
>XP_005258655
          Length = 381

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQDLQQSL 8
           LQDL+Q L
Sbjct: 120 LQDLEQGL 127
>XP_005258654
          Length = 421

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQDLQQSL 8
           LQDL+Q L
Sbjct: 120 LQDLEQGL 127
>XP_006721500
          Length = 700

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQDLQQSL 8
           LQDLQQ +
Sbjct: 550 LQDLQQQV 557
>XP_005267319
          Length = 789

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QDLQQSLV 9
           QDL QSL+
Sbjct: 634 QDLTQSLI 641
>XP_006715356
          Length = 112

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  QDLQQSL 8
          QDL+QSL
Sbjct: 36 QDLEQSL 42
>XP_006715355
          Length = 127

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  QDLQQSL 8
          QDL+QSL
Sbjct: 51 QDLEQSL 57
>NP_006354
          Length = 767

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QDLQQSLV 9
           QDL QSL+
Sbjct: 612 QDLTQSLI 619
>NP_116781
          Length = 767

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QDLQQSLV 9
           QDL QSL+
Sbjct: 612 QDLTQSLI 619
>NP_057726
          Length = 3674

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LQDLQQSLV 9
           L  LQQSLV
Sbjct: 617 LAQLQQSLV 625
>NP_694945
          Length = 802

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQDLQQSL 8
           LQDL+Q L
Sbjct: 435 LQDLEQRL 442
>NP_115515
          Length = 1050

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LQDLQQ 6
           LQDLQQ
Sbjct: 246 LQDLQQ 251
>NP_003557
          Length = 1411

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LQDLQQ 6
           LQDLQQ
Sbjct: 750 LQDLQQ 755
>XP_005259367
          Length = 854

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  LQDLQQ 6
          LQDLQQ
Sbjct: 50 LQDLQQ 55
>XP_006723476
          Length = 979

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LQDLQQ 6
           LQDLQQ
Sbjct: 246 LQDLQQ 251
>XP_006723475
          Length = 1050

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LQDLQQ 6
           LQDLQQ
Sbjct: 246 LQDLQQ 251
>XP_005254495
          Length = 3694

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LQDLQQSLV 9
           L  LQQSLV
Sbjct: 637 LAQLQQSLV 645
>XP_006719694
          Length = 1465

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LQDLQQ 6
           LQDLQQ
Sbjct: 804 LQDLQQ 809
>NP_001360
          Length = 4624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    LQDLQQSL 8
            L+D+QQ+L
Sbjct: 1027 LEDVQQTL 1034
>NP_115560
          Length = 1194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    LQDLQQSL 8
            L+DLQ+S+
Sbjct: 1167 LKDLQESI 1174
>NP_001254711
          Length = 1301

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQDLQQSL 8
           LQ+L QSL
Sbjct: 423 LQELDQSL 430
>NP_001254712
          Length = 1179

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQDLQQSL 8
           LQ+L QSL
Sbjct: 423 LQELDQSL 430
>NP_060219
          Length = 1208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQDLQQSL 8
           LQ+L QSL
Sbjct: 423 LQELDQSL 430
>NP_079225
          Length = 1192

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   QDLQQSL 8
           QDL QSL
Sbjct: 240 QDLMQSL 246
>NP_001002034
          Length = 259

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQDLQQSL 8
           LQD +QSL
Sbjct: 135 LQDARQSL 142
>XP_005261430
          Length = 259

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQDLQQSL 8
           LQD +QSL
Sbjct: 135 LQDARQSL 142
>XP_005259087
          Length = 692

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQDLQQSLV 9
           LQ+LQQ ++
Sbjct: 380 LQELQQIII 388
>XP_006723320
          Length = 692

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQDLQQSLV 9
           LQ+LQQ ++
Sbjct: 380 LQELQQIII 388
>XP_005259086
          Length = 694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQDLQQSLV 9
           LQ+LQQ ++
Sbjct: 380 LQELQQIII 388
>XP_006723319
          Length = 694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQDLQQSLV 9
           LQ+LQQ ++
Sbjct: 380 LQELQQIII 388
>XP_005259085
          Length = 694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQDLQQSLV 9
           LQ+LQQ ++
Sbjct: 380 LQELQQIII 388
>XP_006718323
          Length = 1119

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQDLQQSL 8
           LQ+L QSL
Sbjct: 423 LQELDQSL 430
>XP_005253071
          Length = 1208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQDLQQSL 8
           LQ+L QSL
Sbjct: 423 LQELDQSL 430
>XP_005253069
          Length = 1238

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQDLQQSL 8
           LQ+L QSL
Sbjct: 513 LQELDQSL 520
>XP_005253068
          Length = 1269

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQDLQQSL 8
           LQ+L QSL
Sbjct: 513 LQELDQSL 520
>XP_006718322
          Length = 1298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQDLQQSL 8
           LQ+L QSL
Sbjct: 513 LQELDQSL 520
>XP_005253066
          Length = 1298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQDLQQSL 8
           LQ+L QSL
Sbjct: 513 LQELDQSL 520
>XP_005248319
          Length = 4609

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    LQDLQQSL 8
            L+D+QQ+L
Sbjct: 1012 LEDVQQTL 1019
>XP_005248296
          Length = 630

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LQDLQQSL 8
          ++D+QQSL
Sbjct: 72 VKDIQQSL 79
>XP_005248295
          Length = 745

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LQDLQQSL 8
          ++D+QQSL
Sbjct: 72 VKDIQQSL 79
>XP_006714376
          Length = 815

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   QDLQQSL 8
           QDL QSL
Sbjct: 240 QDLMQSL 246
>XP_006714375
          Length = 1208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   QDLQQSL 8
           QDL QSL
Sbjct: 240 QDLMQSL 246
>XP_005271313
          Length = 936

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LQDLQQSL 8
           L+DLQ+S+
Sbjct: 909 LKDLQESI 916
>NP_009208
          Length = 745

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LQDLQQSL 8
          ++D+QQSL
Sbjct: 72 VKDIQQSL 79
>NP_060498
          Length = 694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQDLQQSLV 9
           LQ+LQQ ++
Sbjct: 380 LQELQQIII 388
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.317    0.132    0.310 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 521,749
Number of extensions: 961
Number of successful extensions: 68
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 68
Number of HSP's successfully gapped: 68
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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