Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              20     299
NP_671714                                                              20     299
XP_006715890                                                           20     299
XP_005250160                                                           20     299
XP_005250159                                                           20     299
NP_071400                                                              17    2528
XP_006724655                                                           17    2528
NP_060034                                                              16    5631
NP_002963                                                              16    5631
NP_001123481                                                           16    5631
NP_872431                                                              16    5631
XP_005261992                                                           16    5631
XP_005261991                                                           16    5631
XP_005261989                                                           16    5631
XP_005261988                                                           16    5631
XP_006719539                                                           16    5631
XP_006712069                                                           16    5631
XP_006712068                                                           16    5631
XP_005262670                                                           16    5631
NP_000500                                                              16    7355
NP_068656                                                              16    7355
NP_000821                                                              16    7355
NP_783300                                                              16    7355
NP_066959                                                              16    7355
XP_005261001                                                           16    7355
XP_005261000                                                           16    7355
XP_005260999                                                           16    7355
XP_006724054                                                           16    7355
NP_001116241                                                           15    9605
NP_149347                                                              15    9605
NP_859065                                                              15    9605
NP_004333                                                              15    9605
NP_004358                                                              15    9605
NP_694574                                                              15    9605
NP_113597                                                              15    9605
NP_149130                                                              15    9605
NP_149129                                                              15    9605
NP_149131                                                              15    9605
NP_001276953                                                           15    9605
NP_714912                                                              15    9605
NP_001276952                                                           15    9605
NP_005526                                                              15    9605
NP_001265455                                                           15    9605
NP_002920                                                              15    9605
NP_003804                                                              15    9605
NP_001265454                                                           15    9605
NP_001265453                                                           15    9605
NP_055641                                                              15    9605
NP_055618                                                              15    9605
NP_001095841                                                           15    9605
NP_079231                                                              15    9605
NP_003598                                                              15    9605
NP_997226                                                              15    9605
NP_005093                                                              15    9605
NP_001036013                                                           15    9605
NP_060862                                                              15    9605
NP_001265178                                                           15    9605
XP_006724383                                                           15    9605
XP_006722804                                                           15    9605
XP_005256319                                                           15    9605
XP_006721414                                                           15    9605
XP_006718875                                                           15    9605
XP_006718874                                                           15    9605
XP_006716202                                                           15    9605
XP_006716201                                                           15    9605
XP_006716200                                                           15    9605
XP_006716199                                                           15    9605
XP_005248722                                                           15    9605
XP_005263172                                                           15    9605
XP_006712216                                                           15    9605
XP_005273378                                                           15    9605
NP_001070707                                                           15    9605
>NP_005742
          Length = 3907

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LQFETADNE 9
            LQFETAD+E
Sbjct: 3537 LQFETADDE 3545
>NP_671714
          Length = 3899

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LQFETADNE 9
            LQFETAD+E
Sbjct: 3529 LQFETADDE 3537
>XP_006715890
          Length = 3860

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LQFETADNE 9
            LQFETAD+E
Sbjct: 3490 LQFETADDE 3498
>XP_005250160
          Length = 3939

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LQFETADNE 9
            LQFETAD+E
Sbjct: 3569 LQFETADDE 3577
>XP_005250159
          Length = 3952

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LQFETADNE 9
            LQFETAD+E
Sbjct: 3582 LQFETADDE 3590
>NP_071400
          Length = 693

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   FETADNE 9
           FET DNE
Sbjct: 462 FETTDNE 468
>XP_006724655
          Length = 694

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   FETADNE 9
           FET DNE
Sbjct: 462 FETTDNE 468
>NP_060034
          Length = 2551

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   LQFETADN 8
           +QF T DN
Sbjct: 616 IQFNTTDN 623
>NP_002963
          Length = 1893

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    QFETADNE 9
            QF+TA++E
Sbjct: 1779 QFQTAESE 1786
>NP_001123481
          Length = 908

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FETADNE 9
           +ETA+NE
Sbjct: 857 YETAENE 863
>NP_872431
          Length = 908

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FETADNE 9
           +ETA+NE
Sbjct: 857 YETAENE 863
>XP_005261992
          Length = 1867

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    QFETADNE 9
            QF+TA++E
Sbjct: 1753 QFQTAESE 1760
>XP_005261991
          Length = 1868

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    QFETADNE 9
            QF+TA++E
Sbjct: 1754 QFQTAESE 1761
>XP_005261989
          Length = 1891

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    QFETADNE 9
            QF+TA++E
Sbjct: 1777 QFQTAESE 1784
>XP_005261988
          Length = 1894

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    QFETADNE 9
            QF+TA++E
Sbjct: 1780 QFQTAESE 1787
>XP_006719539
          Length = 2246

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   LQFETADN 8
           +QF T DN
Sbjct: 616 IQFNTTDN 623
>XP_006712069
          Length = 908

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FETADNE 9
           +ETA+NE
Sbjct: 857 YETAENE 863
>XP_006712068
          Length = 908

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FETADNE 9
           +ETA+NE
Sbjct: 857 YETAENE 863
>XP_005262670
          Length = 908

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FETADNE 9
           +ETA+NE
Sbjct: 857 YETAENE 863
>NP_000500
          Length = 437

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LQFETADNE 9
           +QF T DN+
Sbjct: 336 MQFSTWDND 344
>NP_068656
          Length = 453

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LQFETADNE 9
           +QF T DN+
Sbjct: 336 MQFSTWDND 344
>NP_000821
          Length = 918

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  FETADNE 9
          FET +NE
Sbjct: 43 FETVENE 49
>NP_783300
          Length = 905

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  FETADNE 9
          FET +NE
Sbjct: 43 FETVENE 49
>NP_066959
          Length = 776

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LQFETADN 8
           L +ETA+N
Sbjct: 366 LSYETAEN 373
>XP_005261001
          Length = 903

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  FETADNE 9
          FET +NE
Sbjct: 43 FETVENE 49
>XP_005261000
          Length = 920

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  FETADNE 9
          FET +NE
Sbjct: 43 FETVENE 49
>XP_005260999
          Length = 934

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  FETADNE 9
          FET +NE
Sbjct: 43 FETVENE 49
>XP_006724054
          Length = 949

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  FETADNE 9
          FET +NE
Sbjct: 43 FETVENE 49
>NP_001116241
          Length = 697

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QFETADNE 9
           +FE A+NE
Sbjct: 149 KFEDAENE 156
>NP_149347
          Length = 563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQFETADNE 9
           +Q +TA+NE
Sbjct: 137 MQNDTAENE 145
>NP_859065
          Length = 697

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QFETADNE 9
           +FE A+NE
Sbjct: 149 KFEDAENE 156
>NP_004333
          Length = 538

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQFETADNE 9
           +Q +TA+NE
Sbjct: 137 MQNDTAENE 145
>NP_004358
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ETADNE 9
           ETADN+
Sbjct: 362 ETADND 367
>NP_694574
          Length = 896

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   FETADNE 9
           FET D+E
Sbjct: 197 FETGDDE 203
>NP_113597
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ETADNE 9
           ETADN+
Sbjct: 362 ETADND 367
>NP_149130
          Length = 558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQFETADNE 9
           +Q +TA+NE
Sbjct: 131 MQNDTAENE 139
>NP_149129
          Length = 793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQFETADNE 9
           +Q +TA+NE
Sbjct: 137 MQNDTAENE 145
>NP_149131
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQFETADNE 9
           +Q +TA+NE
Sbjct: 131 MQNDTAENE 139
>NP_001276953
          Length = 702

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LQFETADNE 9
           +++ET DN+
Sbjct: 197 MEWETPDNQ 205
>NP_714912
          Length = 381

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LQFETADNE 9
           +++ET DN+
Sbjct: 157 MEWETPDNQ 165
>NP_001276952
          Length = 660

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LQFETADNE 9
           +++ET DN+
Sbjct: 157 MEWETPDNQ 165
>NP_005526
          Length = 662

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LQFETADNE 9
           +++ET DN+
Sbjct: 157 MEWETPDNQ 165
>NP_001265455
          Length = 953

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  QFETADN 8
          +FET DN
Sbjct: 39 KFETRDN 45
>NP_002920
          Length = 563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   FETADNE 9
           ++TADN+
Sbjct: 95  YDTADND 101
>NP_003804
          Length = 722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LQFETADN 8
           L+FE A+N
Sbjct: 185 LEFEEAEN 192
>NP_001265454
          Length = 1483

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   QFETADN 8
           +FET DN
Sbjct: 569 KFETRDN 575
>NP_001265453
          Length = 1483

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   QFETADN 8
           +FET DN
Sbjct: 569 KFETRDN 575
>NP_055641
          Length = 1638

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   QFETADN 8
           QFET D+
Sbjct: 885 QFETVDS 891
>NP_055618
          Length = 1483

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   QFETADN 8
           +FET DN
Sbjct: 569 KFETRDN 575
>NP_001095841
          Length = 684

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   FETADN 8
           FETA+N
Sbjct: 226 FETAEN 231
>NP_079231
          Length = 684

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   FETADN 8
           FETA+N
Sbjct: 226 FETAEN 231
>NP_003598
          Length = 1719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   QFETADN 8
           QFET D+
Sbjct: 966 QFETVDS 972
>NP_997226
          Length = 703

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FETADNE 9
           F+TAD+E
Sbjct: 209 FKTADSE 215
>NP_005093
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQFETADNE 9
           L F+T+D+E
Sbjct: 130 LLFDTSDDE 138
>NP_001036013
          Length = 380

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQFETADNE 9
           L F+T+D+E
Sbjct: 130 LLFDTSDDE 138
>NP_060862
          Length = 2104

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   FETADNE 9
           FET+D E
Sbjct: 537 FETSDTE 543
>NP_001265178
          Length = 548

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  FETADNE 9
          F+TAD+E
Sbjct: 54 FKTADSE 60
>XP_006724383
          Length = 594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   FETADN 8
           FETA+N
Sbjct: 226 FETAEN 231
>XP_006722804
          Length = 674

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LQFETADNE 9
           +++ET DN+
Sbjct: 157 MEWETPDNQ 165
>XP_005256319
          Length = 678

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   FETADNE 9
           FET D+E
Sbjct: 197 FETGDDE 203
>XP_006721414
          Length = 810

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   FETADNE 9
           FET D+E
Sbjct: 111 FETGDDE 117
>XP_006718875
          Length = 603

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FETADNE 9
           F+TAD+E
Sbjct: 109 FKTADSE 115
>XP_006718874
          Length = 758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FETADNE 9
           F+TAD+E
Sbjct: 264 FKTADSE 270
>XP_006716202
          Length = 537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQFETADNE 9
           +Q +TA+NE
Sbjct: 137 MQNDTAENE 145
>XP_006716201
          Length = 767

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQFETADNE 9
           +Q +TA+NE
Sbjct: 137 MQNDTAENE 145
>XP_006716200
          Length = 787

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQFETADNE 9
           +Q +TA+NE
Sbjct: 131 MQNDTAENE 139
>XP_006716199
          Length = 792

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQFETADNE 9
           +Q +TA+NE
Sbjct: 137 MQNDTAENE 145
>XP_005248722
          Length = 697

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QFETADNE 9
           +FE A+NE
Sbjct: 149 KFEDAENE 156
>XP_005263172
          Length = 2104

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   FETADNE 9
           FET+D E
Sbjct: 537 FETSDTE 543
>XP_006712216
          Length = 279

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LQFETADNE 9
          L F+T+D+E
Sbjct: 29 LLFDTSDDE 37
>XP_005273378
          Length = 1781

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   QFETADN 8
           QFET D+
Sbjct: 966 QFETVDS 972
>NP_001070707
          Length = 703

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FETADNE 9
           F+TAD+E
Sbjct: 209 FKTADSE 215
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.304    0.123    0.316 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 534,152
Number of extensions: 1006
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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