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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005350                                                              18    1482
NP_006319                                                              16    5631
NP_001185765                                                           16    5631
NP_001185766                                                           16    5631
NP_001185775                                                           16    5631
NP_001185774                                                           16    5631
NP_001127911                                                           16    7355
NP_001127910                                                           16    7355
NP_665696                                                              16    7355
NP_001127909                                                           16    7355
NP_057311                                                              15    9605
NP_055098                                                              15    9605
NP_001269679                                                           15    9605
XP_005245308                                                           15    9605
XP_006711439                                                           15    9605
XP_006711438                                                           15    9605
XP_006711437                                                           15    9605

>NP_005350
          Length = 552

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NISVASTSQ 9
           NI VASTSQ
Sbjct: 216 NIPVASTSQ 224



>NP_006319
          Length = 669

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  NISVASTSQ 9
          N+S A TSQ
Sbjct: 85 NVSAACTSQ 93



>NP_001185765
          Length = 156

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  NISVASTSQ 9
          N+S A TSQ
Sbjct: 85 NVSAACTSQ 93



>NP_001185766
          Length = 119

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  NISVASTSQ 9
          N+S A TSQ
Sbjct: 85 NVSAACTSQ 93



>NP_001185775
          Length = 118

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  NISVASTSQ 9
          N+S A TSQ
Sbjct: 85 NVSAACTSQ 93



>NP_001185774
          Length = 339

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  NISVASTSQ 9
          N+S A TSQ
Sbjct: 85 NVSAACTSQ 93



>NP_001127911
          Length = 1253

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    NISVASTS 8
            NIS ASTS
Sbjct: 1023 NISSASTS 1030



>NP_001127910
          Length = 1253

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    NISVASTS 8
            NIS ASTS
Sbjct: 1023 NISSASTS 1030



>NP_665696
          Length = 1210

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   NISVASTS 8
           NIS ASTS
Sbjct: 980 NISSASTS 987



>NP_001127909
          Length = 1237

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    NISVASTS 8
            NIS ASTS
Sbjct: 1007 NISSASTS 1014



>NP_057311
          Length = 1405

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NISVASTSQ 9
           NIS +STS+
Sbjct: 290 NISSSSTSE 298



>NP_055098
          Length = 1254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NISVASTSQ 9
           NIS +STS+
Sbjct: 132 NISSSSTSE 140



>NP_001269679
          Length = 883

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NISVASTSQ 9
           NIS +STS+
Sbjct: 95  NISSSSTSE 103



>XP_005245308
          Length = 1092

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NISVASTSQ 9
           NIS +STS+
Sbjct: 132 NISSSSTSE 140



>XP_006711439
          Length = 1210

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NISVASTSQ 9
           NIS +STS+
Sbjct: 95  NISSSSTSE 103



>XP_006711438
          Length = 1217

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NISVASTSQ 9
           NIS +STS+
Sbjct: 95  NISSSSTSE 103



>XP_006711437
          Length = 1247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NISVASTSQ 9
           NIS +STS+
Sbjct: 132 NISSSSTSE 140



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.286   0.0950    0.201 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 211,734
Number of extensions: 271
Number of successful extensions: 17
Number of sequences better than 10000.0: 17
Number of HSP's gapped: 17
Number of HSP's successfully gapped: 17
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)