Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245236                                                           17    3301
NP_997193                                                              17    3301
NP_620125                                                              17    3301
NP_001245233                                                           17    3301
NP_001245235                                                           17    3301
XP_006712900                                                           17    3301
XP_005263899                                                           17    3301
XP_006712898                                                           17    3301
XP_006712897                                                           17    3301
XP_005263897                                                           17    3301
XP_006712896                                                           17    3301
XP_005263896                                                           17    3301
XP_005263895                                                           17    3301
XP_005263894                                                           17    3301
XP_006712894                                                           17    3301
XP_005263892                                                           17    3301
XP_006712891                                                           17    3301
XP_005263893                                                           17    3301
NP_001135389                                                           17    4312
NP_000101                                                              16    5631
XP_006721627                                                           16    5631
XP_006721626                                                           16    5631
XP_006710460                                                           16    5631
XP_005270619                                                           16    5631
NP_065950                                                              16    5631
NP_001122305                                                           16    5631
NP_001162                                                              16    7355
NP_055863                                                              16    7355
NP_001161957                                                           16    7355
NP_001161954                                                           16    7355
NP_001161951                                                           16    7355
NP_001161952                                                           16    7355
NP_073749                                                              16    7355
NP_001161950                                                           16    7355
NP_001138820                                                           16    7355
NP_079049                                                              16    7355
XP_006721155                                                           16    7355
XP_006719359                                                           16    7355
XP_006719358                                                           16    7355
XP_005253915                                                           16    7355
NP_006152                                                              16    7355
NP_065861                                                              15    9605
NP_005682                                                              15    9605
NP_064693                                                              15    9605
NP_000187                                                              15    9605
NP_001243838                                                           15    9605
NP_073740                                                              15    9605
NP_001180268                                                           15    9605
NP_066279                                                              15    9605
NP_001265516                                                           15    9605
NP_079119                                                              15    9605
NP_001180269                                                           15    9605
NP_001011554                                                           15    9605
NP_001131136                                                           15    9605
NP_057322                                                              15    9605
NP_071889                                                              15    9605
NP_001008747                                                           15    9605
NP_786951                                                              15    9605
XP_005267973                                                           15    9605
XP_006719513                                                           15    9605
XP_005253348                                                           15    9605
XP_005253347                                                           15    9605
XP_006719088                                                           15    9605
XP_005253346                                                           15    9605
XP_005253344                                                           15    9605
XP_005253345                                                           15    9605
XP_005253343                                                           15    9605
XP_005253341                                                           15    9605
XP_006712788                                                           15    9605
XP_006712786                                                           15    9605
XP_005264216                                                           15    9605
NP_848656                                                              15    9605
NP_001254479                                                           15    9605
>NP_001245236
          Length = 314

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLALRAVLP 9
           P+A RA+LP
Sbjct: 276 PVAERAILP 284
>NP_997193
          Length = 380

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLALRAVLP 9
           P+A RA+LP
Sbjct: 342 PVAERAILP 350
>NP_620125
          Length = 378

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLALRAVLP 9
           P+A RA+LP
Sbjct: 340 PVAERAILP 348
>NP_001245233
          Length = 375

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLALRAVLP 9
           P+A RA+LP
Sbjct: 337 PVAERAILP 345
>NP_001245235
          Length = 312

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLALRAVLP 9
           P+A RA+LP
Sbjct: 274 PVAERAILP 282
>XP_006712900
          Length = 318

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLALRAVLP 9
           P+A RA+LP
Sbjct: 280 PVAERAILP 288
>XP_005263899
          Length = 356

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLALRAVLP 9
           P+A RA+LP
Sbjct: 318 PVAERAILP 326
>XP_006712898
          Length = 360

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLALRAVLP 9
           P+A RA+LP
Sbjct: 322 PVAERAILP 330
>XP_006712897
          Length = 384

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLALRAVLP 9
           P+A RA+LP
Sbjct: 346 PVAERAILP 354
>XP_005263897
          Length = 422

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLALRAVLP 9
           P+A RA+LP
Sbjct: 384 PVAERAILP 392
>XP_006712896
          Length = 426

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLALRAVLP 9
           P+A RA+LP
Sbjct: 388 PVAERAILP 396
>XP_005263896
          Length = 482

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLALRAVLP 9
           P+A RA+LP
Sbjct: 444 PVAERAILP 452
>XP_005263895
          Length = 482

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLALRAVLP 9
           P+A RA+LP
Sbjct: 444 PVAERAILP 452
>XP_005263894
          Length = 210

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLALRAVLP 9
           P+A RA+LP
Sbjct: 172 PVAERAILP 180
>XP_006712894
          Length = 298

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLALRAVLP 9
           P+A RA+LP
Sbjct: 260 PVAERAILP 268
>XP_005263892
          Length = 354

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLALRAVLP 9
           P+A RA+LP
Sbjct: 316 PVAERAILP 324
>XP_006712891
          Length = 420

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLALRAVLP 9
           P+A RA+LP
Sbjct: 382 PVAERAILP 390
>XP_005263893
          Length = 480

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLALRAVLP 9
           P+A RA+LP
Sbjct: 442 PVAERAILP 450
>NP_001135389
          Length = 1335

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PLALRAVLP 9
           P+AL  VLP
Sbjct: 273 PMALHMVLP 281
>NP_000101
          Length = 1025

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   PLALRAV 7
           P+ALRAV
Sbjct: 772 PIALRAV 778
>XP_006721627
          Length = 1013

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PLALRAVLP 9
           P+AL  VLP
Sbjct: 945 PVALNMVLP 953
>XP_006721626
          Length = 1013

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PLALRAVLP 9
           P+AL  VLP
Sbjct: 945 PVALNMVLP 953
>XP_006710460
          Length = 889

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   PLALRAV 7
           P+ALRAV
Sbjct: 772 PIALRAV 778
>XP_005270619
          Length = 953

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   PLALRAV 7
           P+ALRAV
Sbjct: 700 PIALRAV 706
>NP_065950
          Length = 1013

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PLALRAVLP 9
           P+AL  VLP
Sbjct: 945 PVALNMVLP 953
>NP_001122305
          Length = 1013

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PLALRAVLP 9
           P+AL  VLP
Sbjct: 945 PVALNMVLP 953
>NP_001162
          Length = 1503

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    PLALRAVLP 9
            PLA  A+LP
Sbjct: 1085 PLATVAILP 1093
>NP_055863
          Length = 1923

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    PLALRAVL 8
            PLAL AVL
Sbjct: 1440 PLALPAVL 1447
>NP_001161957
          Length = 558

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PLALRAVLP 9
           PLA R+++P
Sbjct: 96  PLAERSIVP 104
>NP_001161954
          Length = 558

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PLALRAVLP 9
           PLA R+++P
Sbjct: 96  PLAERSIVP 104
>NP_001161951
          Length = 558

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PLALRAVLP 9
           PLA R+++P
Sbjct: 96  PLAERSIVP 104
>NP_001161952
          Length = 558

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PLALRAVLP 9
           PLA R+++P
Sbjct: 96  PLAERSIVP 104
>NP_073749
          Length = 558

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PLALRAVLP 9
           PLA R+++P
Sbjct: 96  PLAERSIVP 104
>NP_001161950
          Length = 558

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PLALRAVLP 9
           PLA R+++P
Sbjct: 96  PLAERSIVP 104
>NP_001138820
          Length = 454

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  ALRAVLP 9
          ALRA+LP
Sbjct: 59 ALRALLP 65
>NP_079049
          Length = 416

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  ALRAVLP 9
          ALRA+LP
Sbjct: 21 ALRALLP 27
>XP_006721155
          Length = 427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  ALRAVLP 9
          ALRA+LP
Sbjct: 32 ALRALLP 38
>XP_006719359
          Length = 1966

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    PLALRAVL 8
            PLAL AVL
Sbjct: 1483 PLALPAVL 1490
>XP_006719358
          Length = 1966

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    PLALRAVL 8
            PLAL AVL
Sbjct: 1483 PLALPAVL 1490
>XP_005253915
          Length = 1966

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    PLALRAVL 8
            PLAL AVL
Sbjct: 1483 PLALPAVL 1490
>NP_006152
          Length = 237

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ALRAVLP 9
           ALR+VLP
Sbjct: 114 ALRSVLP 120
>NP_065861
          Length = 509

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LRAVLP 9
           LRAVLP
Sbjct: 186 LRAVLP 191
>NP_005682
          Length = 1549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLALRAV 7
           P+A+RAV
Sbjct: 252 PIAMRAV 258
>NP_064693
          Length = 1549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLALRAV 7
           P+A+RAV
Sbjct: 252 PIAMRAV 258
>NP_000187
          Length = 405

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  PLALRAVL 8
          P+A RAVL
Sbjct: 79 PVATRAVL 86
>NP_001243838
          Length = 228

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  PLALRAVL 8
          PL+LRA L
Sbjct: 90 PLSLRAFL 97
>NP_073740
          Length = 602

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  PLALRAVLP 9
          PL++ A+LP
Sbjct: 58 PLSVTALLP 66
>NP_001180268
          Length = 552

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  PLALRAVLP 9
          PL++ A+LP
Sbjct: 58 PLSVTALLP 66
>NP_066279
          Length = 214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ALRAVLP 9
           ALR VLP
Sbjct: 105 ALRGVLP 111
>NP_001265516
          Length = 296

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PLALRAVLP 9
          PLAL  +LP
Sbjct: 50 PLALWGMLP 58
>NP_079119
          Length = 286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PLALRAVL 8
           PL+LRA L
Sbjct: 148 PLSLRAFL 155
>NP_001180269
          Length = 520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  PLALRAVLP 9
          PL++ A+LP
Sbjct: 11 PLSVTALLP 19
>NP_001011554
          Length = 555

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  PLALRAVLP 9
          PL++ A+LP
Sbjct: 11 PLSVTALLP 19
>NP_001131136
          Length = 537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PLALRAVL 8
           PLAL A+L
Sbjct: 200 PLALDAIL 207
>NP_057322
          Length = 599

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PLALRAVL 8
           PLAL A+L
Sbjct: 200 PLALDAIL 207
>NP_071889
          Length = 595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  PLALRAVLP 9
          PL++ A+LP
Sbjct: 54 PLSVTALLP 62
>NP_001008747
          Length = 777

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PLALRAVLP 9
           PL L  VLP
Sbjct: 546 PLGLSPVLP 554
>NP_786951
          Length = 214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LALRAVLP 9
           LAL+A LP
Sbjct: 97  LALQAALP 104
>XP_005267973
          Length = 537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LRAVLP 9
           LRAVLP
Sbjct: 214 LRAVLP 219
>XP_006719513
          Length = 552

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PLALRAVL 8
           PLAL A+L
Sbjct: 153 PLALDAIL 160
>XP_005253348
          Length = 1229

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLALRAV 7
           P+A+RAV
Sbjct: 252 PIAMRAV 258
>XP_005253347
          Length = 1502

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLALRAV 7
           P+A+RAV
Sbjct: 252 PIAMRAV 258
>XP_006719088
          Length = 1536

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLALRAV 7
           P+A+RAV
Sbjct: 252 PIAMRAV 258
>XP_005253346
          Length = 1536

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLALRAV 7
           P+A+RAV
Sbjct: 252 PIAMRAV 258
>XP_005253344
          Length = 1549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLALRAV 7
           P+A+RAV
Sbjct: 252 PIAMRAV 258
>XP_005253345
          Length = 1549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLALRAV 7
           P+A+RAV
Sbjct: 252 PIAMRAV 258
>XP_005253343
          Length = 1549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLALRAV 7
           P+A+RAV
Sbjct: 252 PIAMRAV 258
>XP_005253341
          Length = 1549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLALRAV 7
           P+A+RAV
Sbjct: 252 PIAMRAV 258
>XP_006712788
          Length = 24022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PLALRAVLP 9
           P ALR V+P
Sbjct: 100 PEALREVVP 108
>XP_006712786
          Length = 35484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1     PLALRAVLP 9
             P ALR V+P
Sbjct: 11562 PEALREVVP 11570
>XP_005264216
          Length = 210

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LALRAVLP 9
           LAL+A LP
Sbjct: 97  LALQAALP 104
>NP_848656
          Length = 777

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PLALRAVLP 9
           PL L  VLP
Sbjct: 546 PLGLSPVLP 554
>NP_001254479
          Length = 35991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1     PLALRAVLP 9
             P ALR V+P
Sbjct: 12069 PEALREVVP 12077
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.330    0.147    0.438 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 378,293
Number of extensions: 785
Number of successful extensions: 73
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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