Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           19     665
NP_001185763                                                           19     665
NP_055459                                                              19     665
NP_001002811                                                           19     665
NP_001002812                                                           19     665
XP_006726410                                                           19     665
XP_006711719                                                           19     665
XP_006711717                                                           19     665
XP_006711716                                                           19     665
XP_006711715                                                           19     665
XP_006711714                                                           19     665
XP_006711713                                                           19     665
XP_006711712                                                           19     665
XP_006711711                                                           19     665
XP_006711710                                                           19     665
XP_006711709                                                           19     665
XP_005277503                                                           19     665
XP_005273038                                                           19     665
XP_006711708                                                           19     665
XP_005277500                                                           19     665
XP_006711707                                                           19     665
XP_005277499                                                           19     665
XP_006711706                                                           19     665
XP_006711705                                                           19     665
XP_006711164                                                           19     665
NP_060030                                                              17    3301
NP_001193907                                                           17    4312
NP_001193908                                                           17    4312
NP_001193906                                                           17    4312
NP_001193921                                                           17    4312
NP_001193922                                                           17    4312
NP_005114                                                              17    4312
XP_006719782                                                           17    4312
NP_001130008                                                           16    7355
NP_002902                                                              16    7355
NP_001361                                                              16    7355
NP_001164171                                                           16    7355
XP_005260072                                                           16    7355
XP_006714077                                                           16    7355
XP_006712019                                                           16    7355
NP_115963                                                              15    9605
NP_065733                                                              15    9605
NP_277025                                                              15    9605
NP_001278274                                                           15    9605
NP_277024                                                              15    9605
NP_277022                                                              15    9605
NP_001778                                                              15    9605
NP_277021                                                              15    9605
NP_694960                                                              15    9605
NP_115627                                                              15    9605
NP_001129663                                                           15    9605
NP_001186887                                                           15    9605
NP_056308                                                              15    9605
NP_073617                                                              15    9605
NP_076916                                                              15    9605
NP_277071                                                              15    9605
NP_065868                                                              15    9605
NP_002483                                                              15    9605
XP_006721791                                                           15    9605
XP_006718583                                                           15    9605
XP_006718582                                                           15    9605
XP_005247738                                                           15    9605
XP_006713778                                                           15    9605
XP_006712182                                                           15    9605
XP_005264669                                                           15    9605
XP_006712181                                                           15    9605
XP_006712180                                                           15    9605
XP_006711133                                                           15    9605
XP_006711131                                                           15    9605
XP_006711129                                                           15    9605
XP_006711128                                                           15    9605
XP_006711127                                                           15    9605
XP_006711126                                                           15    9605
XP_006711125                                                           15    9605
NP_001186886                                                           15    9605
>NP_001185761
          Length = 2240

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   GQSEIAEE 9
           GQSEIAEE
Sbjct: 674 GQSEIAEE 681
>NP_001185763
          Length = 2362

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   GQSEIAEE 9
           GQSEIAEE
Sbjct: 608 GQSEIAEE 615
>NP_055459
          Length = 2346

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   GQSEIAEE 9
           GQSEIAEE
Sbjct: 608 GQSEIAEE 615
>NP_001002811
          Length = 1132

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   GQSEIAEE 9
           GQSEIAEE
Sbjct: 771 GQSEIAEE 778
>NP_001002812
          Length = 969

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   GQSEIAEE 9
           GQSEIAEE
Sbjct: 608 GQSEIAEE 615
>XP_006726410
          Length = 2087

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   GQSEIAEE 9
           GQSEIAEE
Sbjct: 683 GQSEIAEE 690
>XP_006711719
          Length = 2302

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   GQSEIAEE 9
           GQSEIAEE
Sbjct: 674 GQSEIAEE 681
>XP_006711717
          Length = 2385

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   GQSEIAEE 9
           GQSEIAEE
Sbjct: 674 GQSEIAEE 681
>XP_006711716
          Length = 2411

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   GQSEIAEE 9
           GQSEIAEE
Sbjct: 674 GQSEIAEE 681
>XP_006711715
          Length = 2428

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   GQSEIAEE 9
           GQSEIAEE
Sbjct: 608 GQSEIAEE 615
>XP_006711714
          Length = 2429

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   GQSEIAEE 9
           GQSEIAEE
Sbjct: 608 GQSEIAEE 615
>XP_006711713
          Length = 2432

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   GQSEIAEE 9
           GQSEIAEE
Sbjct: 611 GQSEIAEE 618
>XP_006711712
          Length = 2473

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   GQSEIAEE 9
           GQSEIAEE
Sbjct: 771 GQSEIAEE 778
>XP_006711711
          Length = 2482

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   GQSEIAEE 9
           GQSEIAEE
Sbjct: 771 GQSEIAEE 778
>XP_006711710
          Length = 2494

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   GQSEIAEE 9
           GQSEIAEE
Sbjct: 674 GQSEIAEE 681
>XP_006711709
          Length = 2495

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   GQSEIAEE 9
           GQSEIAEE
Sbjct: 674 GQSEIAEE 681
>XP_005277503
          Length = 2498

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   GQSEIAEE 9
           GQSEIAEE
Sbjct: 771 GQSEIAEE 778
>XP_005273038
          Length = 2509

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   GQSEIAEE 9
           GQSEIAEE
Sbjct: 771 GQSEIAEE 778
>XP_006711708
          Length = 2512

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   GQSEIAEE 9
           GQSEIAEE
Sbjct: 771 GQSEIAEE 778
>XP_005277500
          Length = 2525

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   GQSEIAEE 9
           GQSEIAEE
Sbjct: 771 GQSEIAEE 778
>XP_006711707
          Length = 2553

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   GQSEIAEE 9
           GQSEIAEE
Sbjct: 771 GQSEIAEE 778
>XP_005277499
          Length = 2561

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   GQSEIAEE 9
           GQSEIAEE
Sbjct: 771 GQSEIAEE 778
>XP_006711706
          Length = 2591

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   GQSEIAEE 9
           GQSEIAEE
Sbjct: 771 GQSEIAEE 778
>XP_006711705
          Length = 2592

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   GQSEIAEE 9
           GQSEIAEE
Sbjct: 771 GQSEIAEE 778
>XP_006711164
          Length = 2087

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   GQSEIAEE 9
           GQSEIAEE
Sbjct: 683 GQSEIAEE 690
>NP_060030
          Length = 659

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  GQSEIAEE 9
          G SEIAEE
Sbjct: 74 GASEIAEE 81
>NP_001193907
          Length = 425

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QGQSEIAE 8
           QG++E+AE
Sbjct: 98  QGETEVAE 105
>NP_001193908
          Length = 476

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QGQSEIAE 8
           QG++E+AE
Sbjct: 98  QGETEVAE 105
>NP_001193906
          Length = 476

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QGQSEIAE 8
           QG++E+AE
Sbjct: 98  QGETEVAE 105
>NP_001193921
          Length = 482

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QGQSEIAE 8
           QG++E+AE
Sbjct: 108 QGETEVAE 115
>NP_001193922
          Length = 486

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QGQSEIAE 8
           QG++E+AE
Sbjct: 108 QGETEVAE 115
>NP_005114
          Length = 472

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QGQSEIAE 8
           QG++E+AE
Sbjct: 98  QGETEVAE 105
>XP_006719782
          Length = 284

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QGQSEIAE 8
           QG++E+AE
Sbjct: 108 QGETEVAE 115
>NP_001130008
          Length = 616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   GQSEIAEE 9
           G+S++AEE
Sbjct: 587 GRSDLAEE 594
>NP_002902
          Length = 1118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   QGQSEIA 7
           QGQ EIA
Sbjct: 752 QGQEEIA 758
>NP_001361
          Length = 4158

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QGQSEIAEE 9
            QGQ  IAE+
Sbjct: 3576 QGQGPIAEK 3584
>NP_001164171
          Length = 781

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   GQSEIAEE 9
           G+S++AEE
Sbjct: 752 GRSDLAEE 759
>XP_005260072
          Length = 1129

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   QGQSEIA 7
           QGQ EIA
Sbjct: 763 QGQEEIA 769
>XP_006714077
          Length = 906

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   GQSEIAEE 9
           G+S++AEE
Sbjct: 877 GRSDLAEE 884
>XP_006712019
          Length = 4158

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QGQSEIAEE 9
            QGQ  IAE+
Sbjct: 3576 QGQGPIAEK 3584
>NP_115963
          Length = 99

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1  QGQSEIAE 8
          +GQ+++AE
Sbjct: 8  EGQTQVAE 15
>NP_065733
          Length = 375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QGQSEIAEE 9
           +GQ E+AE+
Sbjct: 105 KGQVEVAEK 113
>NP_277025
          Length = 565

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GQSEIAEE 9
           G+SE AEE
Sbjct: 152 GESEEAEE 159
>NP_001278274
          Length = 772

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GQSEIAEE 9
           G+SE AEE
Sbjct: 359 GESEEAEE 366
>NP_277024
          Length = 748

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GQSEIAEE 9
           G+SE AEE
Sbjct: 335 GESEEAEE 342
>NP_277022
          Length = 526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GQSEIAEE 9
           G+SE AEE
Sbjct: 113 GESEEAEE 120
>NP_001778
          Length = 795

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GQSEIAEE 9
           G+SE AEE
Sbjct: 382 GESEEAEE 389
>NP_277021
          Length = 782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GQSEIAEE 9
           G+SE AEE
Sbjct: 369 GESEEAEE 376
>NP_694960
          Length = 763

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QGQSEIAE 8
           +GQSE+ E
Sbjct: 382 KGQSEVLE 389
>NP_115627
          Length = 1476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QGQSEIAEE 9
           + QSE AEE
Sbjct: 836 RAQSEAAEE 844
>NP_001129663
          Length = 851

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   GQSEIA 7
           GQSEIA
Sbjct: 817 GQSEIA 822
>NP_001186887
          Length = 135

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GQSEIAE 8
           GQ+E+AE
Sbjct: 94  GQAELAE 100
>NP_056308
          Length = 859

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   GQSEIA 7
           GQSEIA
Sbjct: 825 GQSEIA 830
>NP_073617
          Length = 391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QGQSEIAEE 9
           QG  ++AEE
Sbjct: 129 QGMLDVAEE 137
>NP_076916
          Length = 780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GQSEIAEE 9
           G+SE AEE
Sbjct: 367 GESEEAEE 374
>NP_277071
          Length = 770

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GQSEIAEE 9
           G+SE AEE
Sbjct: 357 GESEEAEE 364
>NP_065868
          Length = 936

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QGQSEIAEE 9
           QG+ EIA E
Sbjct: 857 QGKHEIAAE 865
>NP_002483
          Length = 189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GQSEIAE 8
           GQ+E+AE
Sbjct: 94  GQAELAE 100
>XP_006721791
          Length = 1078

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QGQSEIAE 8
           +GQSE+ E
Sbjct: 311 KGQSEVLE 318
>XP_006718583
          Length = 1482

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QGQSEIAEE 9
           + QSE AEE
Sbjct: 758 RAQSEAAEE 766
>XP_006718582
          Length = 1560

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QGQSEIAEE 9
           + QSE AEE
Sbjct: 836 RAQSEAAEE 844
>XP_005247738
          Length = 615

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QGQSEIAEE 9
           QG+ EIA E
Sbjct: 536 QGKHEIAAE 544
>XP_006713778
          Length = 923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QGQSEIAEE 9
           QG+ EIA E
Sbjct: 844 QGKHEIAAE 852
>XP_006712182
          Length = 99

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1  QGQSEIAE 8
          +GQ+++AE
Sbjct: 8  EGQTQVAE 15
>XP_005264669
          Length = 120

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1  QGQSEIAE 8
          +GQ+++AE
Sbjct: 8  EGQTQVAE 15
>XP_006712181
          Length = 120

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1  QGQSEIAE 8
          +GQ+++AE
Sbjct: 8  EGQTQVAE 15
>XP_006712180
          Length = 120

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1  QGQSEIAE 8
          +GQ+++AE
Sbjct: 8  EGQTQVAE 15
>XP_006711133
          Length = 409

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GQSEIAEE 9
           G+SE AEE
Sbjct: 369 GESEEAEE 376
>XP_006711131
          Length = 738

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GQSEIAEE 9
           G+SE AEE
Sbjct: 325 GESEEAEE 332
>XP_006711129
          Length = 781

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GQSEIAEE 9
           G+SE AEE
Sbjct: 368 GESEEAEE 375
>XP_006711128
          Length = 785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GQSEIAEE 9
           G+SE AEE
Sbjct: 372 GESEEAEE 379
>XP_006711127
          Length = 791

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GQSEIAEE 9
           G+SE AEE
Sbjct: 378 GESEEAEE 385
>XP_006711126
          Length = 795

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GQSEIAEE 9
           G+SE AEE
Sbjct: 382 GESEEAEE 389
>XP_006711125
          Length = 795

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GQSEIAEE 9
           G+SE AEE
Sbjct: 382 GESEEAEE 389
>NP_001186886
          Length = 137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  GQSEIAE 8
          GQ+E+AE
Sbjct: 42 GQAELAE 48
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.283    0.109    0.247 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 510,248
Number of extensions: 968
Number of successful extensions: 75
Number of sequences better than 10000.0: 75
Number of HSP's gapped: 75
Number of HSP's successfully gapped: 75
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.6 bits)
S2: 28 (15.4 bits)

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