Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           18    1135
NP_001185763                                                           18    1135
NP_055459                                                              18    1135
XP_006726436                                                           18    1135
XP_006726410                                                           18    1135
XP_006711784                                                           18    1135
XP_006711719                                                           18    1135
XP_006711718                                                           18    1135
XP_006711717                                                           18    1135
XP_006711716                                                           18    1135
XP_006711715                                                           18    1135
XP_006711714                                                           18    1135
XP_006711713                                                           18    1135
XP_006711712                                                           18    1135
XP_006711711                                                           18    1135
XP_006711710                                                           18    1135
XP_006711709                                                           18    1135
XP_005277503                                                           18    1135
XP_005273038                                                           18    1135
XP_006711708                                                           18    1135
XP_005277500                                                           18    1135
XP_006711707                                                           18    1135
XP_005277499                                                           18    1135
XP_006711706                                                           18    1135
XP_006711705                                                           18    1135
XP_006711164                                                           18    1135
XP_005276114                                                           18    1135
XP_006710122                                                           18    1135
XP_006717822                                                           17    3301
XP_006717821                                                           17    3301
XP_005269749                                                           17    3301
XP_006717820                                                           17    3301
NP_065081                                                              17    3301
NP_619520                                                              16    5631
NP_055781                                                              16    5631
XP_006713096                                                           16    5631
XP_006713095                                                           16    5631
NP_005362                                                              16    7355
NP_079436                                                              16    7355
NP_001108585                                                           16    7355
XP_005268930                                                           16    7355
XP_005273330                                                           16    7355
XP_006711880                                                           16    7355
NP_951059                                                              15    9605
NP_060119                                                              15    9605
NP_951058                                                              15    9605
NP_005436                                                              15    9605
NP_001121685                                                           15    9605
NP_001121684                                                           15    9605
NP_064569                                                              15    9605
NP_055991                                                              15    9605
NP_001012734                                                           15    9605
XP_005256258                                                           15    9605
XP_005256256                                                           15    9605
XP_006717971                                                           15    9605
XP_005269990                                                           15    9605
XP_005263972                                                           15    9605
XP_005263971                                                           15    9605
XP_006712405                                                           15    9605
XP_006712404                                                           15    9605
XP_005246413                                                           15    9605
NP_689741                                                              15    9605
>NP_001185761
          Length = 2240

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LELRTKVS 9
            LELRTKVS
Sbjct: 2174 LELRTKVS 2181
>NP_001185763
          Length = 2362

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LELRTKVS 9
            LELRTKVS
Sbjct: 2280 LELRTKVS 2287
>NP_055459
          Length = 2346

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LELRTKVS 9
            LELRTKVS
Sbjct: 2280 LELRTKVS 2287
>XP_006726436
          Length = 178

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LELRTKVS 9
          LELRTKVS
Sbjct: 58 LELRTKVS 65
>XP_006726410
          Length = 2087

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LELRTKVS 9
            LELRTKVS
Sbjct: 2021 LELRTKVS 2028
>XP_006711784
          Length = 178

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LELRTKVS 9
          LELRTKVS
Sbjct: 58 LELRTKVS 65
>XP_006711719
          Length = 2302

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LELRTKVS 9
            LELRTKVS
Sbjct: 2236 LELRTKVS 2243
>XP_006711718
          Length = 1436

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LELRTKVS 9
            LELRTKVS
Sbjct: 1287 LELRTKVS 1294
>XP_006711717
          Length = 2385

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LELRTKVS 9
            LELRTKVS
Sbjct: 2236 LELRTKVS 2243
>XP_006711716
          Length = 2411

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LELRTKVS 9
            LELRTKVS
Sbjct: 2345 LELRTKVS 2352
>XP_006711715
          Length = 2428

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LELRTKVS 9
            LELRTKVS
Sbjct: 2279 LELRTKVS 2286
>XP_006711714
          Length = 2429

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LELRTKVS 9
            LELRTKVS
Sbjct: 2280 LELRTKVS 2287
>XP_006711713
          Length = 2432

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LELRTKVS 9
            LELRTKVS
Sbjct: 2283 LELRTKVS 2290
>XP_006711712
          Length = 2473

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LELRTKVS 9
            LELRTKVS
Sbjct: 2324 LELRTKVS 2331
>XP_006711711
          Length = 2482

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LELRTKVS 9
            LELRTKVS
Sbjct: 2333 LELRTKVS 2340
>XP_006711710
          Length = 2494

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LELRTKVS 9
            LELRTKVS
Sbjct: 2345 LELRTKVS 2352
>XP_006711709
          Length = 2495

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LELRTKVS 9
            LELRTKVS
Sbjct: 2346 LELRTKVS 2353
>XP_005277503
          Length = 2498

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LELRTKVS 9
            LELRTKVS
Sbjct: 2443 LELRTKVS 2450
>XP_005273038
          Length = 2509

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LELRTKVS 9
            LELRTKVS
Sbjct: 2443 LELRTKVS 2450
>XP_006711708
          Length = 2512

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LELRTKVS 9
            LELRTKVS
Sbjct: 2363 LELRTKVS 2370
>XP_005277500
          Length = 2525

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LELRTKVS 9
            LELRTKVS
Sbjct: 2443 LELRTKVS 2450
>XP_006711707
          Length = 2553

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LELRTKVS 9
            LELRTKVS
Sbjct: 2404 LELRTKVS 2411
>XP_005277499
          Length = 2561

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LELRTKVS 9
            LELRTKVS
Sbjct: 2443 LELRTKVS 2450
>XP_006711706
          Length = 2591

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LELRTKVS 9
            LELRTKVS
Sbjct: 2442 LELRTKVS 2449
>XP_006711705
          Length = 2592

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LELRTKVS 9
            LELRTKVS
Sbjct: 2443 LELRTKVS 2450
>XP_006711164
          Length = 2087

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LELRTKVS 9
            LELRTKVS
Sbjct: 2021 LELRTKVS 2028
>XP_005276114
          Length = 134

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LELRTKVS 9
          LELRTKVS
Sbjct: 28 LELRTKVS 35
>XP_006710122
          Length = 126

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LELRTKVS 9
          LELRTKVS
Sbjct: 58 LELRTKVS 65
>XP_006717822
          Length = 810

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LELRTKV 8
           LELRTKV
Sbjct: 422 LELRTKV 428
>XP_006717821
          Length = 846

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LELRTKV 8
           LELRTKV
Sbjct: 422 LELRTKV 428
>XP_005269749
          Length = 901

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LELRTKV 8
           LELRTKV
Sbjct: 422 LELRTKV 428
>XP_006717820
          Length = 949

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LELRTKV 8
           LELRTKV
Sbjct: 422 LELRTKV 428
>NP_065081
          Length = 951

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LELRTKV 8
           LELRTKV
Sbjct: 422 LELRTKV 428
>NP_619520
          Length = 1194

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RLELRTKVS 9
           R +L+TKVS
Sbjct: 756 RYDLKTKVS 764
>NP_055781
          Length = 1155

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RLELRTKVS 9
           R +L+TKVS
Sbjct: 717 RYDLKTKVS 725
>XP_006713096
          Length = 1162

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RLELRTKVS 9
           R +L+TKVS
Sbjct: 724 RYDLKTKVS 732
>XP_006713095
          Length = 1222

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RLELRTKVS 9
           R +L+TKVS
Sbjct: 784 RYDLKTKVS 792
>NP_005362
          Length = 276

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LELRTKVS 9
           LE+R KVS
Sbjct: 106 LEIRVKVS 113
>NP_079436
          Length = 661

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ELRTKVS 9
           ELRTK+S
Sbjct: 436 ELRTKMS 442
>NP_001108585
          Length = 645

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ELRTKVS 9
           ELRTK+S
Sbjct: 420 ELRTKMS 426
>XP_005268930
          Length = 233

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LELRTKVS 9
          LE+R KVS
Sbjct: 63 LEIRVKVS 70
>XP_005273330
          Length = 599

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ELRTKVS 9
           ELRTK+S
Sbjct: 436 ELRTKMS 442
>XP_006711880
          Length = 660

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ELRTKVS 9
           ELRTK+S
Sbjct: 435 ELRTKMS 441
>NP_951059
          Length = 552

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LELRTK 7
           LELRTK
Sbjct: 439 LELRTK 444
>NP_060119
          Length = 875

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LELRTK 7
           LELRTK
Sbjct: 439 LELRTK 444
>NP_951058
          Length = 853

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LELRTK 7
           LELRTK
Sbjct: 439 LELRTK 444
>NP_005436
          Length = 1217

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ELRTKVS 9
           EL+TK+S
Sbjct: 276 ELKTKIS 282
>NP_001121685
          Length = 476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ELRTKV 8
           ELRTKV
Sbjct: 392 ELRTKV 397
>NP_001121684
          Length = 476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ELRTKV 8
           ELRTKV
Sbjct: 392 ELRTKV 397
>NP_064569
          Length = 775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LELRTK 7
           LELRTK
Sbjct: 366 LELRTK 371
>NP_055991
          Length = 368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ELRTKV 8
           ELRTKV
Sbjct: 284 ELRTKV 289
>NP_001012734
          Length = 123

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  RLELRTK 7
          R+E+RTK
Sbjct: 63 RIEVRTK 69
>XP_005256258
          Length = 1397

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    ELRTKVS 9
            ELRTK++
Sbjct: 1391 ELRTKIN 1397
>XP_005256256
          Length = 1427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    ELRTKVS 9
            ELRTK++
Sbjct: 1421 ELRTKIN 1427
>XP_006717971
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LELRTK 7
           LELRTK
Sbjct: 439 LELRTK 444
>XP_005269990
          Length = 564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LELRTK 7
           LELRTK
Sbjct: 439 LELRTK 444
>XP_005263972
          Length = 776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LELRTK 7
           LELRTK
Sbjct: 366 LELRTK 371
>XP_005263971
          Length = 796

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LELRTK 7
           LELRTK
Sbjct: 366 LELRTK 371
>XP_006712405
          Length = 238

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ELRTKV 8
           ELRTKV
Sbjct: 154 ELRTKV 159
>XP_006712404
          Length = 307

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ELRTKV 8
           ELRTKV
Sbjct: 223 ELRTKV 228
>XP_005246413
          Length = 384

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ELRTKV 8
           ELRTKV
Sbjct: 300 ELRTKV 305
>NP_689741
          Length = 476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ELRTKV 8
           ELRTKV
Sbjct: 392 ELRTKV 397
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.319    0.131    0.309 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 384,396
Number of extensions: 528
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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