Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              17    2528
XP_006716142                                                           17    2528
XP_005250088                                                           17    2528
XP_006716141                                                           17    2528
XP_005250085                                                           17    2528
XP_006716140                                                           17    2528
XP_005250084                                                           17    2528
XP_005250083                                                           17    2528
XP_005250082                                                           17    2528
NP_055335                                                              17    4312
NP_001099008                                                           17    4312
XP_006721482                                                           17    4312
XP_005256470                                                           17    4312
NP_055244                                                              16    5631
XP_005247419                                                           16    5631
NP_004594                                                              16    7355
NP_001258857                                                           16    7355
NP_001258856                                                           16    7355
NP_001159375                                                           16    7355
NP_060046                                                              16    7355
XP_005252149                                                           16    7355
XP_005252148                                                           16    7355
XP_005252147                                                           16    7355
XP_005252146                                                           16    7355
XP_006717239                                                           16    7355
XP_005250609                                                           16    7355
NP_001153844                                                           15    9605
NP_113654                                                              15    9605
NP_066000                                                              15    9605
NP_892006                                                              15    9605
NP_149062                                                              15    9605
NP_006763                                                              15    9605
NP_004223                                                              15    9605
XP_006722640                                                           15    9605
XP_005266840                                                           15    9605
XP_006716727                                                           15    9605
XP_005251134                                                           15    9605
XP_006715488                                                           15    9605
XP_006715487                                                           15    9605
XP_006715486                                                           15    9605
XP_006715485                                                           15    9605
XP_006715484                                                           15    9605
XP_006715483                                                           15    9605
XP_006715482                                                           15    9605
XP_006715481                                                           15    9605
XP_006715480                                                           15    9605
XP_006715479                                                           15    9605
XP_006715478                                                           15    9605
XP_006715477                                                           15    9605
XP_006715476                                                           15    9605
XP_006715475                                                           15    9605
XP_006715474                                                           15    9605
XP_006715473                                                           15    9605
XP_006715472                                                           15    9605
XP_006715471                                                           15    9605
XP_006715470                                                           15    9605
XP_006713781                                                           15    9605
NP_000979                                                              15    9605
NP_116193                                                              15    9605
>NP_733751
          Length = 4911

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RSKLKSLIG 9
           RSKLKS IG
Sbjct: 909 RSKLKSGIG 917
>XP_006716142
          Length = 4927

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RSKLKSLIG 9
           RSKLKS IG
Sbjct: 910 RSKLKSGIG 918
>XP_005250088
          Length = 4928

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RSKLKSLIG 9
           RSKLKS IG
Sbjct: 910 RSKLKSGIG 918
>XP_006716141
          Length = 4959

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RSKLKSLIG 9
           RSKLKS IG
Sbjct: 910 RSKLKSGIG 918
>XP_005250085
          Length = 4979

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RSKLKSLIG 9
           RSKLKS IG
Sbjct: 910 RSKLKSGIG 918
>XP_006716140
          Length = 4982

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RSKLKSLIG 9
           RSKLKS IG
Sbjct: 910 RSKLKSGIG 918
>XP_005250084
          Length = 4982

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RSKLKSLIG 9
           RSKLKS IG
Sbjct: 910 RSKLKSGIG 918
>XP_005250083
          Length = 4982

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RSKLKSLIG 9
           RSKLKS IG
Sbjct: 909 RSKLKSGIG 917
>XP_005250082
          Length = 4983

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RSKLKSLIG 9
           RSKLKS IG
Sbjct: 910 RSKLKSGIG 918
>NP_055335
          Length = 1328

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SKLKSLIG 9
           SKLK L+G
Sbjct: 227 SKLKKLVG 234
>NP_001099008
          Length = 1332

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SKLKSLIG 9
           SKLK L+G
Sbjct: 227 SKLKKLVG 234
>XP_006721482
          Length = 723

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SKLKSLIG 9
           SKLK L+G
Sbjct: 227 SKLKKLVG 234
>XP_005256470
          Length = 1120

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SKLKSLIG 9
           SKLK L+G
Sbjct: 227 SKLKKLVG 234
>NP_055244
          Length = 984

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KLKSLIG 9
           KLKSL+G
Sbjct: 388 KLKSLLG 394
>XP_005247419
          Length = 1014

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KLKSLIG 9
           KLKSL+G
Sbjct: 388 KLKSLLG 394
>NP_004594
          Length = 288

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  RSKLKSL 7
          RSKLKS+
Sbjct: 90 RSKLKSI 96
>NP_001258857
          Length = 1304

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    RSKLKSLIG 9
            + KLK L+G
Sbjct: 1124 KKKLKELVG 1132
>NP_001258856
          Length = 1335

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    RSKLKSLIG 9
            + KLK L+G
Sbjct: 1155 KKKLKELVG 1163
>NP_001159375
          Length = 251

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  RSKLKSL 7
          RSKLKS+
Sbjct: 90 RSKLKSI 96
>NP_060046
          Length = 1401

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    RSKLKSLIG 9
            + KLK L+G
Sbjct: 1221 KKKLKELVG 1229
>XP_005252149
          Length = 921

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RSKLKSLIG 9
           + KLK L+G
Sbjct: 741 KKKLKELVG 749
>XP_005252148
          Length = 1043

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RSKLKSLIG 9
           + KLK L+G
Sbjct: 863 KKKLKELVG 871
>XP_005252147
          Length = 1329

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    RSKLKSLIG 9
            + KLK L+G
Sbjct: 1149 KKKLKELVG 1157
>XP_005252146
          Length = 1342

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    RSKLKSLIG 9
            + KLK L+G
Sbjct: 1162 KKKLKELVG 1170
>XP_006717239
          Length = 1401

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    RSKLKSLIG 9
            + KLK L+G
Sbjct: 1221 KKKLKELVG 1229
>XP_005250609
          Length = 280

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  RSKLKSL 7
          RSKLKS+
Sbjct: 90 RSKLKSI 96
>NP_001153844
          Length = 1148

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KLKSLIG 9
           K+KSL+G
Sbjct: 556 KMKSLLG 562
>NP_113654
          Length = 1246

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KLKSLIG 9
           K+KSL+G
Sbjct: 654 KMKSLLG 660
>NP_066000
          Length = 771

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   KLKSLIG 9
           KLK LIG
Sbjct: 532 KLKKLIG 538
>NP_892006
          Length = 8797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SKLKSLIG 9
            SKL S++G
Sbjct: 1495 SKLSSIVG 1502
>NP_149062
          Length = 8749

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SKLKSLIG 9
            SKL S++G
Sbjct: 1502 SKLSSIVG 1509
>NP_006763
          Length = 1343

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    SKLKSLIG 9
            S++KS+IG
Sbjct: 1257 SQIKSIIG 1264
>NP_004223
          Length = 535

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  RSKLKSLIG 9
          RSK +SL+G
Sbjct: 67 RSKSESLMG 75
>XP_006722640
          Length = 535

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  RSKLKSLIG 9
          RSK +SL+G
Sbjct: 67 RSKSESLMG 75
>XP_005266840
          Length = 535

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  RSKLKSLIG 9
          RSK +SL+G
Sbjct: 67 RSKSESLMG 75
>XP_006716727
          Length = 1139

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KLKSLIG 9
           K+KSL+G
Sbjct: 547 KMKSLLG 553
>XP_005251134
          Length = 1148

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KLKSLIG 9
           K+KSL+G
Sbjct: 556 KMKSLLG 562
>XP_006715488
          Length = 8721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SKLKSLIG 9
            SKL S++G
Sbjct: 1502 SKLSSIVG 1509
>XP_006715487
          Length = 8744

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SKLKSLIG 9
            SKL S++G
Sbjct: 1502 SKLSSIVG 1509
>XP_006715486
          Length = 8758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SKLKSLIG 9
            SKL S++G
Sbjct: 1502 SKLSSIVG 1509
>XP_006715485
          Length = 8793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SKLKSLIG 9
            SKL S++G
Sbjct: 1449 SKLSSIVG 1456
>XP_006715484
          Length = 8794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SKLKSLIG 9
            SKL S++G
Sbjct: 1502 SKLSSIVG 1509
>XP_006715483
          Length = 8795

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SKLKSLIG 9
            SKL S++G
Sbjct: 1502 SKLSSIVG 1509
>XP_006715482
          Length = 8797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SKLKSLIG 9
            SKL S++G
Sbjct: 1495 SKLSSIVG 1502
>XP_006715481
          Length = 8799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SKLKSLIG 9
            SKL S++G
Sbjct: 1455 SKLSSIVG 1462
>XP_006715480
          Length = 8799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SKLKSLIG 9
            SKL S++G
Sbjct: 1502 SKLSSIVG 1509
>XP_006715479
          Length = 8804

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SKLKSLIG 9
            SKL S++G
Sbjct: 1502 SKLSSIVG 1509
>XP_006715478
          Length = 8809

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SKLKSLIG 9
            SKL S++G
Sbjct: 1502 SKLSSIVG 1509
>XP_006715477
          Length = 8822

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SKLKSLIG 9
            SKL S++G
Sbjct: 1478 SKLSSIVG 1485
>XP_006715476
          Length = 8823

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SKLKSLIG 9
            SKL S++G
Sbjct: 1502 SKLSSIVG 1509
>XP_006715475
          Length = 8827

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SKLKSLIG 9
            SKL S++G
Sbjct: 1502 SKLSSIVG 1509
>XP_006715474
          Length = 8829

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SKLKSLIG 9
            SKL S++G
Sbjct: 1485 SKLSSIVG 1492
>XP_006715473
          Length = 8832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SKLKSLIG 9
            SKL S++G
Sbjct: 1502 SKLSSIVG 1509
>XP_006715472
          Length = 8839

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SKLKSLIG 9
            SKL S++G
Sbjct: 1495 SKLSSIVG 1502
>XP_006715471
          Length = 8842

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SKLKSLIG 9
            SKL S++G
Sbjct: 1502 SKLSSIVG 1509
>XP_006715470
          Length = 8846

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SKLKSLIG 9
            SKL S++G
Sbjct: 1502 SKLSSIVG 1509
>XP_006713781
          Length = 771

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   KLKSLIG 9
           KLK LIG
Sbjct: 532 KLKKLIG 538
>NP_000979
          Length = 136

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  RSKLKSLI 8
          RSK+KS +
Sbjct: 65 RSKIKSFV 72
>NP_116193
          Length = 270

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  SKLKSLI 8
          SKLKSL+
Sbjct: 52 SKLKSLL 58
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.315    0.135    0.329 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 348,180
Number of extensions: 613
Number of successful extensions: 59
Number of sequences better than 10000.0: 59
Number of HSP's gapped: 59
Number of HSP's successfully gapped: 59
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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