Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_064450                                                              19     665
XP_005273257                                                           19     665
NP_056442                                                              19     869
NP_005531                                                              17    2528
XP_006710684                                                           17    2528
XP_006710683                                                           17    2528
XP_006710682                                                           17    2528
XP_005270893                                                           17    2528
XP_005270892                                                           17    2528
XP_005270890                                                           17    2528
NP_659570                                                              17    3301
XP_005250299                                                           17    3301
XP_006715978                                                           17    3301
XP_006715977                                                           17    3301
XP_006715976                                                           17    3301
XP_006715975                                                           17    3301
NP_055384                                                              17    3301
NP_006428                                                              17    4312
NP_612463                                                              17    4312
NP_036442                                                              16    5631
NP_004578                                                              16    5631
NP_001036041                                                           16    5631
NP_001331                                                              16    7355
NP_710142                                                              16    7355
NP_001188267                                                           15    9605
NP_001188269                                                           15    9605
NP_002958                                                              15    9605
NP_001188268                                                           15    9605
NP_001276065                                                           15    9605
NP_004778                                                              15    9605
NP_001276064                                                           15    9605
NP_149082                                                              15    9605
NP_148977                                                              15    9605
NP_001265398                                                           15    9605
NP_001265400                                                           15    9605
NP_001265399                                                           15    9605
NP_001265401                                                           15    9605
NP_055841                                                              15    9605
NP_055464                                                              15    9605
NP_997297                                                              15    9605
XP_006722902                                                           15    9605
XP_005268792                                                           15    9605
XP_005268791                                                           15    9605
XP_005268789                                                           15    9605
XP_005268788                                                           15    9605
XP_005248271                                                           15    9605
XP_006714049                                                           15    9605
XP_005248268                                                           15    9605
XP_006711160                                                           15    9605
>NP_064450
          Length = 1722

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SATEQEDL 8
           SATEQEDL
Sbjct: 188 SATEQEDL 195
>XP_005273257
          Length = 1726

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SATEQEDL 8
           SATEQEDL
Sbjct: 188 SATEQEDL 195
>NP_056442
          Length = 308

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SATEQEDLF 9
           S TEQ+DLF
Sbjct: 298 SGTEQDDLF 306
>NP_005531
          Length = 913

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SATEQEDLF 9
           +A +QEDLF
Sbjct: 763 NAVQQEDLF 771
>XP_006710684
          Length = 794

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SATEQEDLF 9
           +A +QEDLF
Sbjct: 644 NAVQQEDLF 652
>XP_006710683
          Length = 693

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SATEQEDLF 9
           +A +QEDLF
Sbjct: 543 NAVQQEDLF 551
>XP_006710682
          Length = 720

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SATEQEDLF 9
           +A +QEDLF
Sbjct: 570 NAVQQEDLF 578
>XP_005270893
          Length = 749

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SATEQEDLF 9
           +A +QEDLF
Sbjct: 599 NAVQQEDLF 607
>XP_005270892
          Length = 801

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SATEQEDLF 9
           +A +QEDLF
Sbjct: 763 NAVQQEDLF 771
>XP_005270890
          Length = 911

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SATEQEDLF 9
           +A +QEDLF
Sbjct: 761 NAVQQEDLF 769
>NP_659570
          Length = 839

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SATEQEDLF 9
          ++ EQEDLF
Sbjct: 18 TSQEQEDLF 26
>XP_005250299
          Length = 766

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SATEQEDLF 9
          ++ EQEDLF
Sbjct: 18 TSQEQEDLF 26
>XP_006715978
          Length = 766

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SATEQEDLF 9
          ++ EQEDLF
Sbjct: 18 TSQEQEDLF 26
>XP_006715977
          Length = 838

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SATEQEDLF 9
          ++ EQEDLF
Sbjct: 18 TSQEQEDLF 26
>XP_006715976
          Length = 839

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SATEQEDLF 9
          ++ EQEDLF
Sbjct: 18 TSQEQEDLF 26
>XP_006715975
          Length = 839

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SATEQEDLF 9
          ++ EQEDLF
Sbjct: 18 TSQEQEDLF 26
>NP_055384
          Length = 839

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SATEQEDLF 9
          ++ EQEDLF
Sbjct: 18 TSQEQEDLF 26
>NP_006428
          Length = 1724

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SATEQED 7
           SATE+ED
Sbjct: 122 SATEEED 128
>NP_612463
          Length = 212

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SATEQEDLF 9
          S  EQ+DLF
Sbjct: 82 STEEQQDLF 90
>NP_036442
          Length = 1232

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  ATEQEDLF 9
          +TEQE++F
Sbjct: 58 STEQEEVF 65
>NP_004578
          Length = 977

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   ATEQED 7
           ATEQED
Sbjct: 277 ATEQED 282
>NP_001036041
          Length = 977

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   ATEQED 7
           ATEQED
Sbjct: 277 ATEQED 282
>NP_001331
          Length = 348

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SATEQED 7
           SATE ED
Sbjct: 174 SATESED 180
>NP_710142
          Length = 899

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SATEQEDL 8
           S TE+EDL
Sbjct: 473 SETEREDL 480
>NP_001188267
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   EQEDLF 9
           E+EDLF
Sbjct: 256 EEEDLF 261
>NP_001188269
          Length = 848

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   EQEDLF 9
           E+EDLF
Sbjct: 187 EEEDLF 192
>NP_002958
          Length = 915

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   EQEDLF 9
           E+EDLF
Sbjct: 256 EEEDLF 261
>NP_001188268
          Length = 916

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   EQEDLF 9
           E+EDLF
Sbjct: 256 EEEDLF 261
>NP_001276065
          Length = 1521

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    EQEDLF 9
            E+EDLF
Sbjct: 1400 EEEDLF 1405
>NP_004778
          Length = 1529

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    EQEDLF 9
            E+EDLF
Sbjct: 1408 EEEDLF 1413
>NP_001276064
          Length = 1525

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    EQEDLF 9
            E+EDLF
Sbjct: 1404 EEEDLF 1409
>NP_149082
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   EQEDLF 9
           E+EDLF
Sbjct: 186 EEEDLF 191
>NP_148977
          Length = 500

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   EQEDLF 9
           E+EDLF
Sbjct: 212 EEEDLF 217
>NP_001265398
          Length = 1675

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ATEQEDL 8
           +TEQ+DL
Sbjct: 527 STEQQDL 533
>NP_001265400
          Length = 1688

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ATEQEDL 8
           +TEQ+DL
Sbjct: 527 STEQQDL 533
>NP_001265399
          Length = 1711

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ATEQEDL 8
           +TEQ+DL
Sbjct: 527 STEQQDL 533
>NP_001265401
          Length = 1645

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ATEQEDL 8
           +TEQ+DL
Sbjct: 455 STEQQDL 461
>NP_055841
          Length = 1717

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ATEQEDL 8
           +TEQ+DL
Sbjct: 527 STEQQDL 533
>NP_055464
          Length = 953

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   EQEDLF 9
           E+EDLF
Sbjct: 255 EEEDLF 260
>NP_997297
          Length = 1318

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ATEQEDLF 9
           ATE ED++
Sbjct: 178 ATELEDIY 185
>XP_006722902
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   EQEDLF 9
           E+EDLF
Sbjct: 256 EEEDLF 261
>XP_005268792
          Length = 1646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ATEQEDL 8
           +TEQ+DL
Sbjct: 455 STEQQDL 461
>XP_005268791
          Length = 1646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ATEQEDL 8
           +TEQ+DL
Sbjct: 455 STEQQDL 461
>XP_005268789
          Length = 1712

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ATEQEDL 8
           +TEQ+DL
Sbjct: 527 STEQQDL 533
>XP_005268788
          Length = 1718

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ATEQEDL 8
           +TEQ+DL
Sbjct: 527 STEQQDL 533
>XP_005248271
          Length = 1404

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    EQEDLF 9
            E+EDLF
Sbjct: 1283 EEEDLF 1288
>XP_006714049
          Length = 1509

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    EQEDLF 9
            E+EDLF
Sbjct: 1388 EEEDLF 1393
>XP_005248268
          Length = 1533

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    EQEDLF 9
            E+EDLF
Sbjct: 1412 EEEDLF 1417
>XP_006711160
          Length = 304

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TEQEDLF 9
           T+QED F
Sbjct: 277 TQQEDAF 283
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.302    0.118    0.289 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 685,472
Number of extensions: 695
Number of successful extensions: 49
Number of sequences better than 10000.0: 49
Number of HSP's gapped: 49
Number of HSP's successfully gapped: 49
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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