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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_002515                                                              20     299
NP_060107                                                              17    4312
XP_006716851                                                           17    4312
XP_006716850                                                           17    4312
XP_006716849                                                           17    4312
XP_006716848                                                           17    4312
XP_006716847                                                           17    4312
NP_056089                                                              17    4312
NP_001004467                                                           16    5631
NP_001243689                                                           16    7355
NP_000859                                                              16    7355
NP_787055                                                              16    7355
NP_116162                                                              16    7355
NP_062831                                                              16    7355
NP_061916                                                              16    7355
NP_001137474                                                           16    7355
XP_006724566                                                           16    7355
XP_005274619                                                           16    7355
XP_006717514                                                           16    7355
XP_006713856                                                           16    7355
XP_005269424                                                           16    7355
XP_006713855                                                           16    7355
XP_005269422                                                           16    7355
XP_006713854                                                           16    7355
XP_005269420                                                           16    7355
XP_005269419                                                           16    7355
XP_005247569                                                           16    7355
XP_005247568                                                           16    7355
NP_057022                                                              16    7355
NP_056248                                                              16    7355
NP_001182502                                                           15    9605
NP_001258211                                                           15    9605
NP_085124                                                              15    9605
NP_803187                                                              15    9605
NP_689530                                                              15    9605
NP_037517                                                              15    9605
XP_005268685                                                           15    9605

>NP_002515
          Length = 189

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  SFANINLYR 9
          SFA+INLYR
Sbjct: 89 SFADINLYR 97



>NP_060107
          Length = 1099

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ANINLYR 9
           ANINL+R
Sbjct: 883 ANINLHR 889



>XP_006716851
          Length = 1008

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ANINLYR 9
           ANINL+R
Sbjct: 792 ANINLHR 798



>XP_006716850
          Length = 1121

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ANINLYR 9
           ANINL+R
Sbjct: 905 ANINLHR 911



>XP_006716849
          Length = 1125

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ANINLYR 9
           ANINL+R
Sbjct: 909 ANINLHR 915



>XP_006716848
          Length = 1127

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ANINLYR 9
           ANINL+R
Sbjct: 911 ANINLHR 917



>XP_006716847
          Length = 1149

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ANINLYR 9
           ANINL+R
Sbjct: 933 ANINLHR 939



>NP_056089
          Length = 1009

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ANINLY 8
           ANINLY
Sbjct: 257 ANINLY 262



>NP_001004467
          Length = 329

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SFANINLY 8
           SFA IN+Y
Sbjct: 322 SFAFINMY 329



>NP_001243689
          Length = 458

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   NINLYR 9
           N+N+YR
Sbjct: 412 NVNIYR 417



>NP_000859
          Length = 458

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   NINLYR 9
           N+N+YR
Sbjct: 412 NVNIYR 417



>NP_787055
          Length = 586

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  FANINLYR 9
          F +INLY+
Sbjct: 77 FLDINLYK 84



>NP_116162
          Length = 712

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SFANINLYR 9
           S  N+NLY+
Sbjct: 106 SLENLNLYQ 114



>NP_062831
          Length = 586

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  FANINLYR 9
          F +INLY+
Sbjct: 77 FLDINLYK 84



>NP_061916
          Length = 666

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 2   FANINLY 8
           F N+N+Y
Sbjct: 359 FENVNIY 365



>NP_001137474
          Length = 586

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  FANINLYR 9
          F +INLY+
Sbjct: 77 FLDINLYK 84



>XP_006724566
          Length = 586

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  FANINLYR 9
          F +INLY+
Sbjct: 77 FLDINLYK 84



>XP_005274619
          Length = 586

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  FANINLYR 9
          F +INLY+
Sbjct: 77 FLDINLYK 84



>XP_006717514
          Length = 666

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 2   FANINLY 8
           F N+N+Y
Sbjct: 359 FENVNIY 365



>XP_006713856
          Length = 741

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SFANINLYR 9
           S  N+NLY+
Sbjct: 106 SLENLNLYQ 114



>XP_005269424
          Length = 743

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SFANINLYR 9
           S  N+NLY+
Sbjct: 106 SLENLNLYQ 114



>XP_006713855
          Length = 753

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SFANINLYR 9
           S  N+NLY+
Sbjct: 106 SLENLNLYQ 114



>XP_005269422
          Length = 767

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SFANINLYR 9
           S  N+NLY+
Sbjct: 106 SLENLNLYQ 114



>XP_006713854
          Length = 777

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SFANINLYR 9
           S  N+NLY+
Sbjct: 106 SLENLNLYQ 114



>XP_005269420
          Length = 779

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SFANINLYR 9
           S  N+NLY+
Sbjct: 106 SLENLNLYQ 114



>XP_005269419
          Length = 803

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SFANINLYR 9
           S  N+NLY+
Sbjct: 106 SLENLNLYQ 114



>XP_005247569
          Length = 503

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   NINLYR 9
           N+N+YR
Sbjct: 455 NVNIYR 460



>XP_005247568
          Length = 503

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   NINLYR 9
           N+N+YR
Sbjct: 455 NVNIYR 460



>NP_057022
          Length = 503

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   NINLYR 9
           N+N+YR
Sbjct: 455 NVNIYR 460



>NP_056248
          Length = 226

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   NINLYR 9
           N+N+YR
Sbjct: 212 NVNIYR 217



>NP_001182502
          Length = 1829

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    ANINLYR 9
            +N NLYR
Sbjct: 1352 SNCNLYR 1358



>NP_001258211
          Length = 1922

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    ANINLYR 9
            +N NLYR
Sbjct: 1352 SNCNLYR 1358



>NP_085124
          Length = 1922

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    ANINLYR 9
            +N NLYR
Sbjct: 1352 SNCNLYR 1358



>NP_803187
          Length = 1922

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    ANINLYR 9
            +N NLYR
Sbjct: 1352 SNCNLYR 1358



>NP_689530
          Length = 294

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ANINLYR 9
           +NI+LYR
Sbjct: 153 SNISLYR 159



>NP_037517
          Length = 394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   FANINL 7
           FAN+NL
Sbjct: 135 FANLNL 140



>XP_005268685
          Length = 463

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  ANINLYR 9
          +NI+LYR
Sbjct: 86 SNISLYR 92



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.331    0.140    0.402 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 445,628
Number of extensions: 656
Number of successful extensions: 37
Number of sequences better than 10000.0: 37
Number of HSP's gapped: 37
Number of HSP's successfully gapped: 37
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)