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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              18    1135
XP_005262424                                                           18    1135
NP_001273385                                                           17    2528
XP_005249342                                                           17    2528
NP_056297                                                              17    2528
NP_055256                                                              17    4312
NP_055200                                                              17    4312
NP_001185487                                                           17    4312
NP_443729                                                              17    4312
XP_006723209                                                           17    4312
XP_006723203                                                           17    4312
NP_003753                                                              16    5631
NP_001172056                                                           16    5631
NP_976031                                                              16    7355
NP_001035232                                                           15    9605
NP_066287                                                              15    9605
NP_001035233                                                           15    9605
NP_001008563                                                           15    9605
NP_006667                                                              15    9605
NP_001103773                                                           15    9605
XP_006717001                                                           15    9605
XP_005251722                                                           15    9605
XP_005246812                                                           15    9605
XP_005246811                                                           15    9605
XP_005246810                                                           15    9605
XP_005246808                                                           15    9605
XP_005246807                                                           15    9605

>NP_722576
          Length = 3080

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLSVNVTAF 9
            SL VNVTAF
Sbjct: 1515 SLPVNVTAF 1523



>XP_005262424
          Length = 2875

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLSVNVTAF 9
            SL VNVTAF
Sbjct: 1310 SLPVNVTAF 1318



>NP_001273385
          Length = 361

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SLSVNVTAF 9
           +LSVNVT F
Sbjct: 275 ALSVNVTMF 283



>XP_005249342
          Length = 694

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SLSVNVTAF 9
           +LSVNVT F
Sbjct: 275 ALSVNVTMF 283



>NP_056297
          Length = 686

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SLSVNVTAF 9
           +LSVNVT F
Sbjct: 275 ALSVNVTMF 283



>NP_055256
          Length = 463

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LSVNVTA 8
           LSVNVTA
Sbjct: 135 LSVNVTA 141



>NP_055200
          Length = 467

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LSVNVTA 8
           LSVNVTA
Sbjct: 139 LSVNVTA 145



>NP_001185487
          Length = 479

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LSVNVTA 8
           LSVNVTA
Sbjct: 135 LSVNVTA 141



>NP_443729
          Length = 595

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LSVNVTA 8
           LSVNVTA
Sbjct: 137 LSVNVTA 143



>XP_006723209
          Length = 481

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LSVNVTA 8
           LSVNVTA
Sbjct: 135 LSVNVTA 141



>XP_006723203
          Length = 343

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LSVNVTA 8
           LSVNVTA
Sbjct: 139 LSVNVTA 145



>NP_003753
          Length = 141

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  SLSVNVTAF 9
          SLS N TAF
Sbjct: 90 SLSDNATAF 98



>NP_001172056
          Length = 140

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  SLSVNVTAF 9
          SLS N TAF
Sbjct: 89 SLSDNATAF 97



>NP_976031
          Length = 352

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LSVNVTAF 9
           + VN+TAF
Sbjct: 329 VEVNITAF 336



>NP_001035232
          Length = 2005

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   SLSVNVTAF 9
           S  +N+T+F
Sbjct: 287 SFEINITSF 295



>NP_066287
          Length = 2005

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   SLSVNVTAF 9
           S  +N+T+F
Sbjct: 287 SFEINITSF 295



>NP_001035233
          Length = 2005

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   SLSVNVTAF 9
           S  +N+T+F
Sbjct: 287 SFEINITSF 295



>NP_001008563
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  SLSVNVTAF 9
          +L+VN+T F
Sbjct: 71 NLTVNLTTF 79



>NP_006667
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  SLSVNVTAF 9
          +L+VN+T F
Sbjct: 71 NLTVNLTTF 79



>NP_001103773
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  SLSVNVTAF 9
          +L+VN+T F
Sbjct: 71 NLTVNLTTF 79



>XP_006717001
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  SLSVNVTAF 9
          +L+VN+T F
Sbjct: 71 NLTVNLTTF 79



>XP_005251722
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  SLSVNVTAF 9
          +L+VN+T F
Sbjct: 71 NLTVNLTTF 79



>XP_005246812
          Length = 1754

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  SLSVNVTAF 9
          S  +N+T+F
Sbjct: 36 SFEINITSF 44



>XP_005246811
          Length = 1995

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   SLSVNVTAF 9
           S  +N+T+F
Sbjct: 277 SFEINITSF 285



>XP_005246810
          Length = 2005

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   SLSVNVTAF 9
           S  +N+T+F
Sbjct: 287 SFEINITSF 295



>XP_005246808
          Length = 2005

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   SLSVNVTAF 9
           S  +N+T+F
Sbjct: 287 SFEINITSF 295



>XP_005246807
          Length = 2005

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   SLSVNVTAF 9
           S  +N+T+F
Sbjct: 287 SFEINITSF 295



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.318    0.121    0.295 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 269,156
Number of extensions: 298
Number of successful extensions: 27
Number of sequences better than 10000.0: 27
Number of HSP's gapped: 27
Number of HSP's successfully gapped: 27
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)