Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_444256                                                              19     665
NP_444254                                                              19     665
NP_444253                                                              19     665
NP_444255                                                              19     665
XP_005247551                                                           19     665
XP_005247550                                                           19     665
XP_006713712                                                           19     665
XP_005247549                                                           19     665
NP_002197                                                              17    4312
NP_001138468                                                           17    4312
NP_001138469                                                           17    4312
NP_001018098                                                           17    4312
NP_060154                                                              17    4312
NP_060550                                                              17    4312
NP_065872                                                              17    4312
NP_653234                                                              17    4312
XP_005268907                                                           17    4312
XP_005268906                                                           17    4312
XP_005268905                                                           17    4312
XP_005268904                                                           17    4312
XP_005268903                                                           17    4312
XP_005268902                                                           17    4312
XP_005268901                                                           17    4312
XP_005268899                                                           17    4312
XP_005268898                                                           17    4312
XP_005268897                                                           17    4312
XP_005268896                                                           17    4312
XP_006713027                                                           17    4312
XP_006713026                                                           17    4312
XP_006713025                                                           17    4312
XP_006713024                                                           17    4312
NP_828848                                                              17    4312
NP_065978                                                              16    5631
NP_057412                                                              16    7355
NP_001257545                                                           16    7355
NP_002754                                                              16    7355
XP_006716247                                                           16    7355
XP_005250778                                                           16    7355
XP_006711518                                                           16    7355
XP_005273252                                                           16    7355
XP_005273253                                                           16    7355
XP_005273251                                                           16    7355
NP_954635                                                              15    9605
NP_000679                                                              15    9605
NP_001231800                                                           15    9605
NP_001334                                                              15    9605
NP_003310                                                              15    9605
NP_597676                                                              15    9605
NP_001243779                                                           15    9605
NP_596869                                                              15    9605
NP_001091995                                                           15    9605
NP_059509                                                              15    9605
NP_001171019                                                           15    9605
NP_001171020                                                           15    9605
NP_001236                                                              15    9605
NP_942143                                                              15    9605
NP_060674                                                              15    9605
XP_005259653                                                           15    9605
XP_005266401                                                           15    9605
XP_005266400                                                           15    9605
XP_005265002                                                           15    9605
XP_005265001                                                           15    9605
XP_005246888                                                           15    9605
XP_006712788                                                           15    9605
XP_006712787                                                           15    9605
XP_006712786                                                           15    9605
NP_064555                                                              15    9605
NP_001254479                                                           15    9605
NP_001273615                                                           15    9605
NP_597681                                                              15    9605
>NP_444256
          Length = 1794

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SQGTASAFK 9
            SQGTA AFK
Sbjct: 1024 SQGTAPAFK 1032
>NP_444254
          Length = 1845

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SQGTASAFK 9
            SQGTA AFK
Sbjct: 1024 SQGTAPAFK 1032
>NP_444253
          Length = 1914

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SQGTASAFK 9
            SQGTA AFK
Sbjct: 1093 SQGTAPAFK 1101
>NP_444255
          Length = 1863

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SQGTASAFK 9
            SQGTA AFK
Sbjct: 1093 SQGTAPAFK 1101
>XP_005247551
          Length = 1855

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SQGTASAFK 9
            SQGTA AFK
Sbjct: 1034 SQGTAPAFK 1042
>XP_005247550
          Length = 1856

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SQGTASAFK 9
            SQGTA AFK
Sbjct: 1103 SQGTAPAFK 1111
>XP_006713712
          Length = 1923

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SQGTASAFK 9
            SQGTA AFK
Sbjct: 1103 SQGTAPAFK 1111
>XP_005247549
          Length = 1924

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SQGTASAFK 9
            SQGTA AFK
Sbjct: 1103 SQGTAPAFK 1111
>NP_002197
          Length = 1137

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QGTASAF 8
           QGTA+AF
Sbjct: 199 QGTAAAF 205
>NP_001138468
          Length = 1141

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QGTASAF 8
           QGTA+AF
Sbjct: 199 QGTAAAF 205
>NP_001138469
          Length = 1044

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QGTASAF 8
           QGTA+AF
Sbjct: 102 QGTAAAF 108
>NP_001018098
          Length = 3628

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SQGTASAF 8
            S+GTAS F
Sbjct: 2407 SEGTASTF 2414
>NP_060154
          Length = 3710

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SQGTASAF 8
            S+GTAS F
Sbjct: 2364 SEGTASTF 2371
>NP_060550
          Length = 3585

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SQGTASAF 8
            S+GTAS F
Sbjct: 2364 SEGTASTF 2371
>NP_065872
          Length = 3753

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SQGTASAF 8
            S+GTAS F
Sbjct: 2407 SEGTASTF 2414
>NP_653234
          Length = 1107

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SQGTASAF 8
            SQGT S+F
Sbjct: 1056 SQGTVSSF 1063
>XP_005268907
          Length = 979

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  QGTASAF 8
          QGTA+AF
Sbjct: 41 QGTAAAF 47
>XP_005268906
          Length = 1023

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  QGTASAF 8
          QGTA+AF
Sbjct: 41 QGTAAAF 47
>XP_005268905
          Length = 1023

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  QGTASAF 8
          QGTA+AF
Sbjct: 41 QGTAAAF 47
>XP_005268904
          Length = 1023

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  QGTASAF 8
          QGTA+AF
Sbjct: 41 QGTAAAF 47
>XP_005268903
          Length = 1024

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  QGTASAF 8
          QGTA+AF
Sbjct: 86 QGTAAAF 92
>XP_005268902
          Length = 1024

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  QGTASAF 8
          QGTA+AF
Sbjct: 86 QGTAAAF 92
>XP_005268901
          Length = 1068

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  QGTASAF 8
          QGTA+AF
Sbjct: 86 QGTAAAF 92
>XP_005268899
          Length = 1131

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QGTASAF 8
           QGTA+AF
Sbjct: 199 QGTAAAF 205
>XP_005268898
          Length = 1162

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QGTASAF 8
           QGTA+AF
Sbjct: 199 QGTAAAF 205
>XP_005268897
          Length = 1175

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QGTASAF 8
           QGTA+AF
Sbjct: 199 QGTAAAF 205
>XP_005268896
          Length = 1181

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QGTASAF 8
           QGTA+AF
Sbjct: 199 QGTAAAF 205
>XP_006713027
          Length = 930

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SQGTASAF 8
           SQGT S+F
Sbjct: 879 SQGTVSSF 886
>XP_006713026
          Length = 986

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SQGTASAF 8
           SQGT S+F
Sbjct: 935 SQGTVSSF 942
>XP_006713025
          Length = 1089

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SQGTASAF 8
            SQGT S+F
Sbjct: 1038 SQGTVSSF 1045
>XP_006713024
          Length = 1108

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SQGTASAF 8
            SQGT S+F
Sbjct: 1057 SQGTVSSF 1064
>NP_828848
          Length = 818

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   GTASAFK 9
           GTASAF+
Sbjct: 202 GTASAFR 208
>NP_065978
          Length = 419

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GTASAFK 9
           GTAS FK
Sbjct: 211 GTASTFK 217
>NP_057412
          Length = 959

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SQGTASA 7
           SQGTAS+
Sbjct: 654 SQGTASS 660
>NP_001257545
          Length = 737

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  GTASAF 8
          GTASAF
Sbjct: 28 GTASAF 33
>NP_002754
          Length = 737

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  GTASAF 8
          GTASAF
Sbjct: 28 GTASAF 33
>XP_006716247
          Length = 638

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SQGTASA 7
           SQGTAS+
Sbjct: 333 SQGTASS 339
>XP_005250778
          Length = 805

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SQGTASA 7
           SQGTAS+
Sbjct: 654 SQGTASS 660
>XP_006711518
          Length = 680

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  GTASAF 8
          GTASAF
Sbjct: 28 GTASAF 33
>XP_005273252
          Length = 738

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  GTASAF 8
          GTASAF
Sbjct: 28 GTASAF 33
>XP_005273253
          Length = 738

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  GTASAF 8
          GTASAF
Sbjct: 28 GTASAF 33
>XP_005273251
          Length = 738

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  GTASAF 8
          GTASAF
Sbjct: 28 GTASAF 33
>NP_954635
          Length = 640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SQGTAS 6
           SQGTAS
Sbjct: 101 SQGTAS 106
>NP_000679
          Length = 640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SQGTAS 6
           SQGTAS
Sbjct: 101 SQGTAS 106
>NP_001231800
          Length = 749

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   SQGTASAF 8
           S GT SAF
Sbjct: 654 SSGTLSAF 661
>NP_001334
          Length = 770

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   SQGTASAF 8
           S GT SAF
Sbjct: 675 SSGTLSAF 682
>NP_003310
          Length = 26926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1     SQGTASAF 8
             S GT SAF
Sbjct: 16521 SSGTKSAF 16528
>NP_597676
          Length = 27051

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1     SQGTASAF 8
             S GT SAF
Sbjct: 16646 SSGTKSAF 16653
>NP_001243779
          Length = 34350

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1     SQGTASAF 8
             S GT SAF
Sbjct: 23945 SSGTKSAF 23952
>NP_596869
          Length = 33423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1     SQGTASAF 8
             S GT SAF
Sbjct: 23018 SSGTKSAF 23025
>NP_001091995
          Length = 683

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GTASAFK 9
           GT SAFK
Sbjct: 611 GTNSAFK 617
>NP_059509
          Length = 655

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   QGTASA 7
           QGTASA
Sbjct: 361 QGTASA 366
>NP_001171019
          Length = 389

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QGTASAFK 9
           QG ++AFK
Sbjct: 258 QGNSAAFK 265
>NP_001171020
          Length = 342

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QGTASAFK 9
           QG ++AFK
Sbjct: 236 QGNSAAFK 243
>NP_001236
          Length = 453

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QGTASAFK 9
           QG ++AFK
Sbjct: 247 QGNSAAFK 254
>NP_942143
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QGTASAFK 9
           QG ++AFK
Sbjct: 247 QGNSAAFK 254
>NP_060674
          Length = 682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GTASAFK 9
           GT SAFK
Sbjct: 610 GTNSAFK 616
>XP_005259653
          Length = 562

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SQGTASA 7
           SQG+ASA
Sbjct: 165 SQGSASA 171
>XP_005266401
          Length = 635

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GTASAFK 9
           GT SAFK
Sbjct: 563 GTNSAFK 569
>XP_005266400
          Length = 677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GTASAFK 9
           GT SAFK
Sbjct: 605 GTNSAFK 611
>XP_005265002
          Length = 640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SQGTAS 6
           SQGTAS
Sbjct: 101 SQGTAS 106
>XP_005265001
          Length = 657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SQGTAS 6
           SQGTAS
Sbjct: 118 SQGTAS 123
>XP_005246888
          Length = 22663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1     SQGTASAF 8
             S GT SAF
Sbjct: 12258 SSGTKSAF 12265
>XP_006712788
          Length = 24022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1     SQGTASAF 8
             S GT SAF
Sbjct: 13617 SSGTKSAF 13624
>XP_006712787
          Length = 33978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1     SQGTASAF 8
             S GT SAF
Sbjct: 23573 SSGTKSAF 23580
>XP_006712786
          Length = 35484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1     SQGTASAF 8
             S GT SAF
Sbjct: 25079 SSGTKSAF 25086
>NP_064555
          Length = 563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SQGTASA 7
           SQG+ASA
Sbjct: 165 SQGSASA 171
>NP_001254479
          Length = 35991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1     SQGTASAF 8
             S GT SAF
Sbjct: 25586 SSGTKSAF 25593
>NP_001273615
          Length = 634

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GTASAFK 9
           GT SAFK
Sbjct: 562 GTNSAFK 568
>NP_597681
          Length = 27118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1     SQGTASAF 8
             S GT SAF
Sbjct: 16713 SSGTKSAF 16720
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.301    0.107    0.267 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 434,680
Number of extensions: 556
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package