Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001035957                                                           20     509
XP_006721991                                                           20     509
XP_006721990                                                           20     509
XP_006721989                                                           20     509
XP_006721987                                                           20     509
XP_006721986                                                           20     509
XP_005258040                                                           20     509
XP_006721985                                                           20     509
NP_078966                                                              19     665
NP_000258                                                              18    1482
XP_005258041                                                           18    1482
XP_006721988                                                           18    1482
NP_075463                                                              17    2528
XP_006719812                                                           17    2528
XP_006723004                                                           17    3301
NP_002733                                                              17    4312
NP_001073350                                                           17    4312
NP_001073349                                                           17    4312
NP_057541                                                              17    4312
XP_005267916                                                           17    4312
NP_057359                                                              17    4312
NP_005106                                                              16    5631
NP_059447                                                              16    5631
NP_002325                                                              16    5631
NP_001030128                                                           16    5631
XP_006718294                                                           16    5631
XP_005252980                                                           16    5631
NP_112486                                                              16    5631
NP_005804                                                              16    7355
NP_056261                                                              16    7355
NP_671766                                                              16    7355
NP_671756                                                              16    7355
NP_003734                                                              16    7355
XP_006722091                                                           16    7355
XP_006722090                                                           16    7355
XP_006722089                                                           16    7355
XP_006722088                                                           16    7355
XP_006722087                                                           16    7355
XP_006722086                                                           16    7355
XP_006714185                                                           16    7355
XP_006712189                                                           16    7355
XP_005264685                                                           16    7355
XP_005264684                                                           16    7355
XP_005264683                                                           16    7355
XP_005264682                                                           16    7355
XP_005264294                                                           16    7355
XP_006711822                                                           16    7355
XP_006711821                                                           16    7355
NP_001124                                                              16    7355
NP_000468                                                              15    9605
NP_001124170                                                           15    9605
NP_056150                                                              15    9605
NP_065798                                                              15    9605
NP_689533                                                              15    9605
NP_001258214                                                           15    9605
NP_059129                                                              15    9605
NP_076422                                                              15    9605
XP_006719370                                                           15    9605
XP_006719369                                                           15    9605
XP_006719368                                                           15    9605
XP_005268697                                                           15    9605
XP_005268695                                                           15    9605
XP_005272097                                                           15    9605
XP_005272096                                                           15    9605
XP_006714725                                                           15    9605
XP_005272095                                                           15    9605
XP_005272094                                                           15    9605
NP_001166152                                                           15    9605
>NP_001035957
          Length = 2839

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SVVSQRFP 8
            SVVSQRFP
Sbjct: 1391 SVVSQRFP 1398
>XP_006721991
          Length = 1632

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SVVSQRFP 8
            SVVSQRFP
Sbjct: 1401 SVVSQRFP 1408
>XP_006721990
          Length = 2823

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SVVSQRFP 8
            SVVSQRFP
Sbjct: 1401 SVVSQRFP 1408
>XP_006721989
          Length = 2823

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SVVSQRFP 8
            SVVSQRFP
Sbjct: 1401 SVVSQRFP 1408
>XP_006721987
          Length = 2849

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SVVSQRFP 8
            SVVSQRFP
Sbjct: 1401 SVVSQRFP 1408
>XP_006721986
          Length = 2854

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SVVSQRFP 8
            SVVSQRFP
Sbjct: 1388 SVVSQRFP 1395
>XP_005258040
          Length = 2857

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SVVSQRFP 8
            SVVSQRFP
Sbjct: 1391 SVVSQRFP 1398
>XP_006721985
          Length = 2867

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SVVSQRFP 8
            SVVSQRFP
Sbjct: 1401 SVVSQRFP 1408
>NP_078966
          Length = 14507

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SVVSQRFPH 9
            S V+QRFPH
Sbjct: 5891 SPVTQRFPH 5899

 Score = 18.9 bits (37), Expect =   869
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SVVSQRFPH 9
            S ++QRFPH
Sbjct: 7060 STLTQRFPH 7068

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    SVVSQRFPH 9
            S VSQ FPH
Sbjct: 5595 STVSQGFPH 5603

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SVVSQRFPH 9
            S+V Q FPH
Sbjct: 7651 SIVIQGFPH 7659

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SVVSQRFPH 9
            S V+QRF H
Sbjct: 8230 STVTQRFSH 8238

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    SVVSQRFPH 9
            S ++QR PH
Sbjct: 7356 STMTQRLPH 7364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    SVVSQRFP 8
            S  +QRFP
Sbjct: 9397 SATTQRFP 9404
>NP_000258
          Length = 2818

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2    VVSQRFP 8
            VVSQRFP
Sbjct: 1371 VVSQRFP 1377
>XP_005258041
          Length = 2836

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2    VVSQRFP 8
            VVSQRFP
Sbjct: 1371 VVSQRFP 1377
>XP_006721988
          Length = 2846

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2    VVSQRFP 8
            VVSQRFP
Sbjct: 1381 VVSQRFP 1387
>NP_075463
          Length = 3013

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SVVSQRFP 8
            S VSQRFP
Sbjct: 1339 SEVSQRFP 1346
>XP_006719812
          Length = 3019

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    SVVSQRFP 8
            S VSQRFP
Sbjct: 1336 SEVSQRFP 1343
>XP_006723004
          Length = 6443

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SVVSQRFPH 9
           S V+QRF H
Sbjct: 144 STVTQRFSH 152

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    SVVSQRFP 8
            S  +QRFP
Sbjct: 1311 SATTQRFP 1318
>NP_002733
          Length = 912

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  SVVSQRFP 8
          S+V Q+FP
Sbjct: 83 SIVDQKFP 90
>NP_001073350
          Length = 878

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  SVVSQRFP 8
          S+V Q+FP
Sbjct: 75 SIVDQKFP 82
>NP_001073349
          Length = 878

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  SVVSQRFP 8
          S+V Q+FP
Sbjct: 75 SIVDQKFP 82
>NP_057541
          Length = 878

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  SVVSQRFP 8
          S+V Q+FP
Sbjct: 75 SIVDQKFP 82
>XP_005267916
          Length = 920

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  SVVSQRFP 8
          S+V Q+FP
Sbjct: 83 SIVDQKFP 90
>NP_057359
          Length = 195

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  VVSQRFP 8
          V+SQR+P
Sbjct: 61 VISQRYP 67
>NP_005106
          Length = 893

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   VVSQRFPH 9
           VVS R PH
Sbjct: 457 VVSYRVPH 464
>NP_059447
          Length = 893

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   VVSQRFPH 9
           VVS R PH
Sbjct: 457 VVSYRVPH 464
>NP_002325
          Length = 1905

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SVVSQRFPH 9
           +V+SQ  PH
Sbjct: 634 AVISQGLPH 642
>NP_001030128
          Length = 905

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   SQRFPH 9
           SQR+PH
Sbjct: 146 SQRWPH 151
>XP_006718294
          Length = 1808

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SVVSQRFPH 9
           +V+SQ  PH
Sbjct: 634 AVISQGLPH 642
>XP_005252980
          Length = 1809

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SVVSQRFPH 9
           +V+SQ  PH
Sbjct: 634 AVISQGLPH 642
>NP_112486
          Length = 403

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SVVSQRFP 8
           S+V +RFP
Sbjct: 363 SIVEKRFP 370
>NP_005804
          Length = 890

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  SVVSQRFP 8
          S+V Q+FP
Sbjct: 91 SIVYQKFP 98
>NP_056261
          Length = 2275

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SVVSQRFPH 9
           SVVS+  PH
Sbjct: 444 SVVSRTSPH 452
>NP_671766
          Length = 1440

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VVSQRFP 8
           V+S+RFP
Sbjct: 968 VLSERFP 974
>NP_671756
          Length = 1399

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VVSQRFP 8
           V+S+RFP
Sbjct: 968 VLSERFP 974
>NP_003734
          Length = 1441

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VVSQRFP 8
           V+S+RFP
Sbjct: 968 VLSERFP 974
>XP_006722091
          Length = 656

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SVVSQRFPH 9
           +VVSQ  PH
Sbjct: 643 AVVSQSDPH 651
>XP_006722090
          Length = 660

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SVVSQRFPH 9
           +VVSQ  PH
Sbjct: 636 AVVSQSDPH 644
>XP_006722089
          Length = 660

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SVVSQRFPH 9
           +VVSQ  PH
Sbjct: 636 AVVSQSDPH 644
>XP_006722088
          Length = 660

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SVVSQRFPH 9
           +VVSQ  PH
Sbjct: 636 AVVSQSDPH 644
>XP_006722087
          Length = 664

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SVVSQRFPH 9
           +VVSQ  PH
Sbjct: 643 AVVSQSDPH 651
>XP_006722086
          Length = 667

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SVVSQRFPH 9
           +VVSQ  PH
Sbjct: 643 AVVSQSDPH 651
>XP_006714185
          Length = 494

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   SVVSQRFP 8
           +++SQ+FP
Sbjct: 241 AILSQKFP 248
>XP_006712189
          Length = 1394

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VVSQRFP 8
           V+S+RFP
Sbjct: 921 VLSERFP 927
>XP_005264685
          Length = 1399

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VVSQRFP 8
           V+S+RFP
Sbjct: 968 VLSERFP 974
>XP_005264684
          Length = 1399

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VVSQRFP 8
           V+S+RFP
Sbjct: 968 VLSERFP 974
>XP_005264683
          Length = 1440

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VVSQRFP 8
           V+S+RFP
Sbjct: 968 VLSERFP 974
>XP_005264682
          Length = 1441

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VVSQRFP 8
           V+S+RFP
Sbjct: 968 VLSERFP 974
>XP_005264294
          Length = 890

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  SVVSQRFP 8
          S+V Q+FP
Sbjct: 91 SIVYQKFP 98
>XP_006711822
          Length = 2266

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SVVSQRFPH 9
           SVVS+  PH
Sbjct: 435 SVVSRTSPH 443
>XP_006711821
          Length = 2301

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SVVSQRFPH 9
           SVVS+  PH
Sbjct: 470 SVVSRTSPH 478
>NP_001124
          Length = 599

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   SVVSQRFP 8
           +++SQ+FP
Sbjct: 241 AILSQKFP 248
>NP_000468
          Length = 609

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   VSQRFP 8
           +SQRFP
Sbjct: 243 LSQRFP 248
>NP_001124170
          Length = 921

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  SVVSQRFPH 9
          S  SQR PH
Sbjct: 51 SAPSQREPH 59
>NP_056150
          Length = 2210

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4    SQRFPH 9
            SQR PH
Sbjct: 2150 SQRVPH 2155
>NP_065798
          Length = 1512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SVVSQRFP 8
            SV++QR P
Sbjct: 1065 SVITQRHP 1072
>NP_689533
          Length = 438

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   VVSQRFP 8
           VVS RFP
Sbjct: 146 VVSLRFP 152
>NP_001258214
          Length = 218

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   VVSQRFP 8
           VVS RFP
Sbjct: 154 VVSGRFP 160
>NP_059129
          Length = 1616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SVVSQRFP 8
            SVV+QR P
Sbjct: 1308 SVVTQRAP 1315
>NP_076422
          Length = 235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   VVSQRFP 8
           VVS RFP
Sbjct: 171 VVSGRFP 177
>XP_006719370
          Length = 2076

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4    SQRFPH 9
            SQR PH
Sbjct: 2016 SQRVPH 2021
>XP_006719369
          Length = 2200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4    SQRFPH 9
            SQR PH
Sbjct: 2140 SQRVPH 2145
>XP_006719368
          Length = 2209

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4    SQRFPH 9
            SQR PH
Sbjct: 2149 SQRVPH 2154
>XP_005268697
          Length = 217

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   VVSQRFP 8
           VVS RFP
Sbjct: 146 VVSLRFP 152
>XP_005268695
          Length = 424

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   VVSQRFP 8
           VVS RFP
Sbjct: 132 VVSLRFP 138
>XP_005272097
          Length = 1224

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SVVSQRFP 8
           SV++QR P
Sbjct: 777 SVITQRHP 784
>XP_005272096
          Length = 1511

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SVVSQRFP 8
            SV++QR P
Sbjct: 1065 SVITQRHP 1072
>XP_006714725
          Length = 1512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SVVSQRFP 8
            SV++QR P
Sbjct: 1065 SVITQRHP 1072
>XP_005272095
          Length = 1512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SVVSQRFP 8
            SV++QR P
Sbjct: 1065 SVITQRHP 1072
>XP_005272094
          Length = 1512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SVVSQRFP 8
            SV++QR P
Sbjct: 1065 SVITQRHP 1072
>NP_001166152
          Length = 424

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   VVSQRFP 8
           VVS RFP
Sbjct: 132 VVSLRFP 138
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.327    0.131    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 503,553
Number of extensions: 789
Number of successful extensions: 75
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 75
Number of HSP's successfully gapped: 75
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package