Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_443075                                                              17    4312
NP_001258152                                                           17    4312
NP_001092093                                                           17    4312
NP_001129631                                                           17    4312
NP_001129630                                                           17    4312
NP_001129629                                                           17    4312
NP_689929                                                              17    4312
NP_060072                                                              17    4312
XP_005278099                                                           17    4312
XP_005272679                                                           17    4312
XP_006724600                                                           17    4312
XP_005278096                                                           17    4312
XP_005273892                                                           17    4312
XP_005273891                                                           17    4312
XP_005273890                                                           17    4312
XP_006711892                                                           17    4312
XP_006711891                                                           17    4312
XP_006711890                                                           17    4312
XP_006711889                                                           17    4312
XP_005273367                                                           17    4312
XP_005273366                                                           17    4312
XP_006711888                                                           17    4312
XP_006711887                                                           17    4312
XP_005273364                                                           17    4312
XP_005273362                                                           17    4312
XP_005273361                                                           17    4312
XP_006711886                                                           17    4312
XP_006711885                                                           17    4312
XP_005273359                                                           17    4312
XP_006711884                                                           17    4312
XP_005273357                                                           17    4312
XP_005273356                                                           17    4312
XP_005273358                                                           17    4312
XP_005273355                                                           17    4312
XP_005273353                                                           17    4312
XP_005273352                                                           17    4312
XP_005273354                                                           17    4312
XP_005273349                                                           17    4312
XP_006711883                                                           17    4312
XP_005273350                                                           17    4312
XP_005273351                                                           17    4312
XP_006711882                                                           17    4312
XP_005273348                                                           17    4312
XP_005273346                                                           17    4312
XP_005273347                                                           17    4312
XP_005273345                                                           17    4312
XP_005273344                                                           17    4312
NP_848563                                                              16    5631
NP_001265455                                                           16    7355
NP_001265454                                                           16    7355
NP_001265453                                                           16    7355
NP_055618                                                              16    7355
XP_006714322                                                           16    7355
XP_005263177                                                           16    7355
NP_060713                                                              16    7355
NP_005276                                                              16    7355
NP_775831                                                              15    9605
NP_001171899                                                           15    9605
NP_004200                                                              15    9605
NP_689775                                                              15    9605
NP_009160                                                              15    9605
NP_001171900                                                           15    9605
XP_005261376                                                           15    9605
XP_006724183                                                           15    9605
XP_006724182                                                           15    9605
XP_006724181                                                           15    9605
XP_006724180                                                           15    9605
XP_005273475                                                           15    9605
XP_006716359                                                           15    9605
XP_006716358                                                           15    9605
XP_006716357                                                           15    9605
NP_997260                                                              15    9605
>NP_443075
          Length = 6620

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>NP_001258152
          Length = 8923

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>NP_001092093
          Length = 7968

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>NP_001129631
          Length = 349

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VRDKKRAT 8
           + DKKRAT
Sbjct: 160 LEDKKRAT 167
>NP_001129630
          Length = 566

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VRDKKRAT 8
           + DKKRAT
Sbjct: 377 LEDKKRAT 384
>NP_001129629
          Length = 566

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VRDKKRAT 8
           + DKKRAT
Sbjct: 377 LEDKKRAT 384
>NP_689929
          Length = 770

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VRDKKRAT 8
           VRDK+R T
Sbjct: 515 VRDKRRKT 522
>NP_060072
          Length = 571

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VRDKKRAT 8
           + DKKRAT
Sbjct: 382 LEDKKRAT 389
>XP_005278099
          Length = 355

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VRDKKRAT 8
           + DKKRAT
Sbjct: 165 LEDKKRAT 172
>XP_005272679
          Length = 567

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VRDKKRAT 8
           + DKKRAT
Sbjct: 377 LEDKKRAT 384
>XP_006724600
          Length = 571

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VRDKKRAT 8
           + DKKRAT
Sbjct: 382 LEDKKRAT 389
>XP_005278096
          Length = 572

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VRDKKRAT 8
           + DKKRAT
Sbjct: 382 LEDKKRAT 389
>XP_005273892
          Length = 551

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VRDKKRAT 8
           VRDK+R T
Sbjct: 296 VRDKRRKT 303
>XP_005273891
          Length = 740

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VRDKKRAT 8
           VRDK+R T
Sbjct: 485 VRDKRRKT 492
>XP_005273890
          Length = 770

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VRDKKRAT 8
           VRDK+R T
Sbjct: 515 VRDKRRKT 522
>XP_006711892
          Length = 6865

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>XP_006711891
          Length = 8925

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>XP_006711890
          Length = 6957

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>XP_006711889
          Length = 7297

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>XP_005273367
          Length = 7677

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>XP_005273366
          Length = 7678

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>XP_006711888
          Length = 8059

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>XP_006711887
          Length = 8499

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>XP_005273364
          Length = 8653

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>XP_005273362
          Length = 8675

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>XP_005273361
          Length = 8763

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>XP_006711886
          Length = 8833

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>XP_006711885
          Length = 8835

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>XP_005273359
          Length = 8843

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>XP_006711884
          Length = 8847

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>XP_005273357
          Length = 8851

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>XP_005273356
          Length = 8851

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>XP_005273358
          Length = 8851

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>XP_005273355
          Length = 8924

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>XP_005273353
          Length = 8935

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>XP_005273352
          Length = 8935

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>XP_005273354
          Length = 8935

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>XP_005273349
          Length = 8939

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>XP_006711883
          Length = 8939

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>XP_005273350
          Length = 8939

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>XP_005273351
          Length = 8939

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>XP_006711882
          Length = 8977

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>XP_005273348
          Length = 9015

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>XP_005273346
          Length = 9026

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>XP_005273347
          Length = 9026

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>XP_005273345
          Length = 9026

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>XP_005273344
          Length = 9027

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VRDKKRATF 9
           VR+K+ ATF
Sbjct: 344 VREKESATF 352
>NP_848563
          Length = 747

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VRDKKRAT 8
           VRD+KR T
Sbjct: 714 VRDEKRLT 721
>NP_001265455
          Length = 953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VRDKKRAT 8
           V+DK RAT
Sbjct: 371 VKDKLRAT 378
>NP_001265454
          Length = 1483

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VRDKKRAT 8
           V+DK RAT
Sbjct: 901 VKDKLRAT 908
>NP_001265453
          Length = 1483

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VRDKKRAT 8
           V+DK RAT
Sbjct: 901 VKDKLRAT 908
>NP_055618
          Length = 1483

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VRDKKRAT 8
           V+DK RAT
Sbjct: 901 VKDKLRAT 908
>XP_006714322
          Length = 372

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RDKKRATF 9
           +DKK A+F
Sbjct: 364 KDKKNASF 371
>XP_005263177
          Length = 439

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RDKKRATF 9
           +DKK A+F
Sbjct: 431 KDKKNASF 438
>NP_060713
          Length = 429

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RDKKRATF 9
           +DKK A+F
Sbjct: 421 KDKKNASF 428
>NP_005276
          Length = 328

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   RDKKRATF 9
           R KKR TF
Sbjct: 244 RAKKRVTF 251
>NP_775831
          Length = 928

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VRDKKRAT 8
           V+DKK+ T
Sbjct: 114 VKDKKKQT 121
>NP_001171899
          Length = 486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RDKKRAT 8
           R+KK+AT
Sbjct: 315 REKKKAT 321
>NP_004200
          Length = 229

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VRDKKRA 7
           VRD++RA
Sbjct: 98  VRDRRRA 104
>NP_689775
          Length = 1023

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VRDKKRATF 9
           +R +KR TF
Sbjct: 387 MRKRKRVTF 395
>NP_009160
          Length = 486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RDKKRAT 8
           R+KK+AT
Sbjct: 315 REKKKAT 321
>NP_001171900
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RDKKRAT 8
           R+KK+AT
Sbjct: 315 REKKKAT 321
>XP_005261376
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RDKKRAT 8
           R+KK+AT
Sbjct: 315 REKKKAT 321
>XP_006724183
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RDKKRAT 8
           R+KK+AT
Sbjct: 274 REKKKAT 280
>XP_006724182
          Length = 486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RDKKRAT 8
           R+KK+AT
Sbjct: 315 REKKKAT 321
>XP_006724181
          Length = 486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RDKKRAT 8
           R+KK+AT
Sbjct: 315 REKKKAT 321
>XP_006724180
          Length = 486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RDKKRAT 8
           R+KK+AT
Sbjct: 315 REKKKAT 321
>XP_005273475
          Length = 635

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VRDKKRATF 9
           +R +KR TF
Sbjct: 387 MRKRKRVTF 395
>XP_006716359
          Length = 1028

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VRDKKRATF 9
           +R +KR TF
Sbjct: 392 MRKRKRVTF 400
>XP_006716358
          Length = 1028

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VRDKKRATF 9
           +R +KR TF
Sbjct: 392 MRKRKRVTF 400
>XP_006716357
          Length = 1028

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VRDKKRATF 9
           +R +KR TF
Sbjct: 392 MRKRKRVTF 400
>NP_997260
          Length = 152

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  VRDKKRA 7
          +RDK+RA
Sbjct: 43 LRDKRRA 49
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.330    0.136    0.372 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 516,998
Number of extensions: 885
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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