Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001136098                                                           19     869
NP_000360                                                              19     869
NP_001018046                                                           19     869
XP_005268096                                                           19     869
XP_006720308                                                           19     869
XP_005268094                                                           19     869
NP_064599                                                              17    3301
XP_005254616                                                           17    3301
XP_005254615                                                           17    3301
XP_005254614                                                           17    3301
NP_570124                                                              17    4312
NP_945119                                                              17    4312
NP_005329                                                              17    4312
NP_064595                                                              17    4312
XP_005254887                                                           17    4312
XP_005250362                                                           17    4312
XP_005250361                                                           17    4312
XP_006715913                                                           17    4312
NP_065433                                                              16    7355
NP_001009921                                                           16    7355
NP_001157888                                                           16    7355
XP_006724703                                                           16    7355
XP_006713619                                                           16    7355
XP_005247310                                                           16    7355
XP_005247308                                                           16    7355
NP_056118                                                              16    7355
NP_006266                                                              15    9605
NP_001578                                                              15    9605
NP_000267                                                              15    9605
NP_001161842                                                           15    9605
NP_001074260                                                           15    9605
NP_055595                                                              15    9605
NP_001276061                                                           15    9605
NP_443081                                                              15    9605
NP_060720                                                              15    9605
NP_066552                                                              15    9605
NP_006769                                                              15    9605
NP_001166033                                                           15    9605
NP_005984                                                              15    9605
NP_001074261                                                           15    9605
XP_005262479                                                           15    9605
XP_005262478                                                           15    9605
XP_006724824                                                           15    9605
XP_006724823                                                           15    9605
XP_005256462                                                           15    9605
XP_006722355                                                           15    9605
XP_005256461                                                           15    9605
XP_005256460                                                           15    9605
XP_005256459                                                           15    9605
XP_005256457                                                           15    9605
XP_005256458                                                           15    9605
XP_006722354                                                           15    9605
XP_005256456                                                           15    9605
XP_006722353                                                           15    9605
XP_005256453                                                           15    9605
XP_005273625                                                           15    9605
XP_006716420                                                           15    9605
XP_006716419                                                           15    9605
XP_006715348                                                           15    9605
XP_005249560                                                           15    9605
NP_001138631                                                           15    9605
>NP_001136098
          Length = 274

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VTSKDIQRI 9
          VT KDIQRI
Sbjct: 39 VTCKDIQRI 47
>NP_000360
          Length = 764

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VTSKDIQRI 9
          VT KDIQRI
Sbjct: 39 VTCKDIQRI 47
>NP_001018046
          Length = 253

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VTSKDIQRI 9
          VT KDIQRI
Sbjct: 39 VTCKDIQRI 47
>XP_005268096
          Length = 253

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VTSKDIQRI 9
          VT KDIQRI
Sbjct: 39 VTCKDIQRI 47
>XP_006720308
          Length = 274

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VTSKDIQRI 9
          VT KDIQRI
Sbjct: 39 VTCKDIQRI 47
>XP_005268094
          Length = 764

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VTSKDIQRI 9
          VT KDIQRI
Sbjct: 39 VTCKDIQRI 47
>NP_064599
          Length = 630

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VTSKDIQR 8
           +TSKD+Q+
Sbjct: 570 ITSKDLQK 577
>XP_005254616
          Length = 610

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VTSKDIQR 8
           +TSKD+Q+
Sbjct: 550 ITSKDLQK 557
>XP_005254615
          Length = 611

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VTSKDIQR 8
           +TSKD+Q+
Sbjct: 551 ITSKDLQK 558
>XP_005254614
          Length = 631

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VTSKDIQR 8
           +TSKD+Q+
Sbjct: 571 ITSKDLQK 578
>NP_570124
          Length = 475

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VTSKDIQRI 9
           +TSKD Q+I
Sbjct: 318 ITSKDQQKI 326
>NP_945119
          Length = 837

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TSKDIQRI 9
           T KD+QR+
Sbjct: 362 TMKDVQRV 369
>NP_005329
          Length = 1037

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VTSKDIQR 8
           V SKD+QR
Sbjct: 839 VASKDLQR 846
>NP_064595
          Length = 837

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TSKDIQRI 9
           T KD+QR+
Sbjct: 362 TMKDVQRV 369
>XP_005254887
          Length = 977

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TSKDIQRI 9
           T KD+QR+
Sbjct: 502 TMKDVQRV 509
>XP_005250362
          Length = 1003

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VTSKDIQR 8
           V SKD+QR
Sbjct: 805 VASKDLQR 812
>XP_005250361
          Length = 1008

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VTSKDIQR 8
           V SKD+QR
Sbjct: 810 VASKDLQR 817
>XP_006715913
          Length = 267

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VTSKDIQRI 9
           +TSKD Q+I
Sbjct: 110 ITSKDQQKI 118
>NP_065433
          Length = 1091

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SKDIQRI 9
           S+DIQRI
Sbjct: 573 SEDIQRI 579
>NP_001009921
          Length = 1428

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VTSKDIQRI 9
           +TS DIQ++
Sbjct: 661 ITSLDIQQV 669
>NP_001157888
          Length = 154

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VTSKDIQ 7
           +TS+DIQ
Sbjct: 112 ITSRDIQ 118
>XP_006724703
          Length = 154

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VTSKDIQ 7
           +TS+DIQ
Sbjct: 112 ITSRDIQ 118
>XP_006713619
          Length = 856

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VTSKDIQRI 9
          +TS DIQ++
Sbjct: 89 ITSLDIQQV 97
>XP_005247310
          Length = 1035

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VTSKDIQRI 9
           +TS DIQ++
Sbjct: 661 ITSLDIQQV 669
>XP_005247308
          Length = 1428

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VTSKDIQRI 9
           +TS DIQ++
Sbjct: 661 ITSLDIQQV 669
>NP_056118
          Length = 1426

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VTSKDIQRI 9
           +TS DIQ++
Sbjct: 659 ITSLDIQQV 667
>NP_006266
          Length = 344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  VTSKDIQR 8
          V  KDIQR
Sbjct: 13 VREKDIQR 20
>NP_001578
          Length = 893

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   VTSKDIQRI 9
           +  KD+QR+
Sbjct: 439 INKKDLQRL 447
>NP_000267
          Length = 901

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   VTSKDIQRI 9
           +  KD+QR+
Sbjct: 439 INKKDLQRL 447
>NP_001161842
          Length = 1782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    TSKDIQR 8
            TSK++QR
Sbjct: 1394 TSKELQR 1400
>NP_001074260
          Length = 194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VTSKDIQR 8
           VTSKD+ R
Sbjct: 104 VTSKDMLR 111
>NP_055595
          Length = 1698

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    TSKDIQR 8
            TSK++QR
Sbjct: 1310 TSKELQR 1316
>NP_001276061
          Length = 134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VTSKDIQR 8
           VTSKD+ R
Sbjct: 95  VTSKDMLR 102
>NP_443081
          Length = 185

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VTSKDIQR 8
           VTSKD+ R
Sbjct: 95  VTSKDMLR 102
>NP_060720
          Length = 658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SKDIQRI 9
           +KDIQR+
Sbjct: 158 NKDIQRL 164
>NP_066552
          Length = 249

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VTSKDIQRI 9
           +T+KDI+ I
Sbjct: 196 LTAKDIEEI 204
>NP_006769
          Length = 481

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VTSKDIQR 8
           V S+D+QR
Sbjct: 383 VVSEDVQR 390
>NP_001166033
          Length = 634

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SKDIQRI 9
           +KDIQR+
Sbjct: 134 NKDIQRL 140
>NP_005984
          Length = 1192

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SKDIQRI 9
            SKDIQ++
Sbjct: 1082 SKDIQKL 1088
>NP_001074261
          Length = 185

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VTSKDIQR 8
           VTSKD+ R
Sbjct: 95  VTSKDMLR 102
>XP_005262479
          Length = 744

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   VTSKDIQRI 9
           +  KD+QR+
Sbjct: 282 INKKDLQRL 290
>XP_005262478
          Length = 835

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   VTSKDIQRI 9
           +  KD+QR+
Sbjct: 373 INKKDLQRL 381
>XP_006724824
          Length = 890

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   VTSKDIQRI 9
           +  KD+QR+
Sbjct: 436 INKKDLQRL 444
>XP_006724823
          Length = 898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   VTSKDIQRI 9
           +  KD+QR+
Sbjct: 436 INKKDLQRL 444
>XP_005256462
          Length = 630

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SKDIQRI 9
           SKDIQ++
Sbjct: 520 SKDIQKL 526
>XP_006722355
          Length = 630

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SKDIQRI 9
           SKDIQ++
Sbjct: 520 SKDIQKL 526
>XP_005256461
          Length = 630

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SKDIQRI 9
           SKDIQ++
Sbjct: 520 SKDIQKL 526
>XP_005256460
          Length = 630

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SKDIQRI 9
           SKDIQ++
Sbjct: 520 SKDIQKL 526
>XP_005256459
          Length = 630

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SKDIQRI 9
           SKDIQ++
Sbjct: 520 SKDIQKL 526
>XP_005256457
          Length = 630

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SKDIQRI 9
           SKDIQ++
Sbjct: 520 SKDIQKL 526
>XP_005256458
          Length = 630

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SKDIQRI 9
           SKDIQ++
Sbjct: 520 SKDIQKL 526
>XP_006722354
          Length = 760

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SKDIQRI 9
           SKDIQ++
Sbjct: 650 SKDIQKL 656
>XP_005256456
          Length = 764

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SKDIQRI 9
           SKDIQ++
Sbjct: 654 SKDIQKL 660
>XP_006722353
          Length = 1165

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SKDIQRI 9
            SKDIQ++
Sbjct: 1055 SKDIQKL 1061
>XP_005256453
          Length = 1175

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SKDIQRI 9
            SKDIQ++
Sbjct: 1065 SKDIQKL 1071
>XP_005273625
          Length = 427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SKDIQRI 9
           +KDIQR+
Sbjct: 158 NKDIQRL 164
>XP_006716420
          Length = 646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SKDIQRI 9
           +KDIQR+
Sbjct: 158 NKDIQRL 164
>XP_006716419
          Length = 676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SKDIQRI 9
           +KDIQR+
Sbjct: 158 NKDIQRL 164
>XP_006715348
          Length = 1734

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    TSKDIQR 8
            TSK++QR
Sbjct: 1342 TSKELQR 1348
>XP_005249560
          Length = 1750

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    TSKDIQR 8
            TSK++QR
Sbjct: 1362 TSKELQR 1368
>NP_001138631
          Length = 637

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SKDIQRI 9
           +KDIQR+
Sbjct: 137 NKDIQRL 143
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.319    0.132    0.320 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 458,264
Number of extensions: 496
Number of successful extensions: 61
Number of sequences better than 10000.0: 61
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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