Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005148                                                              19     869
NP_009297                                                              19     869
NP_001161710                                                           19     869
NP_001161709                                                           19     869
NP_001161708                                                           19     869
NP_009298                                                              19     869
NP_001129473                                                           19     869
NP_005149                                                              19     869
NP_001161711                                                           19     869
XP_005245145                                                           19     869
NP_001129472                                                           19     869
NP_072089                                                              17    4312
NP_001273572                                                           17    4312
NP_057026                                                              17    4312
NP_001020016                                                           17    4312
NP_964012                                                              17    4312
NP_008865                                                              17    4312
NP_001248309                                                           17    4312
XP_005272689                                                           17    4312
XP_006716632                                                           17    4312
XP_005250984                                                           17    4312
XP_006716631                                                           17    4312
XP_005250983                                                           17    4312
XP_006710903                                                           17    4312
NP_055132                                                              16    5631
NP_001009                                                              16    5631
NP_075048                                                              16    5631
NP_001124397                                                           16    7355
NP_055405                                                              16    7355
NP_055906                                                              16    7355
NP_001171671                                                           16    7355
NP_006768                                                              16    7355
NP_001013652                                                           16    7355
XP_006720146                                                           16    7355
XP_005267508                                                           16    7355
XP_006712074                                                           16    7355
XP_005264351                                                           16    7355
XP_006712072                                                           16    7355
XP_006712071                                                           16    7355
XP_006710671                                                           16    7355
NP_006479                                                              16    7355
NP_000072                                                              15    9605
NP_001257903                                                           15    9605
NP_001159450                                                           15    9605
NP_653308                                                              15    9605
NP_001159449                                                           15    9605
NP_001166104                                                           15    9605
NP_001166103                                                           15    9605
NP_002534                                                              15    9605
XP_006721269                                                           15    9605
XP_006719144                                                           15    9605
XP_005263937                                                           15    9605
XP_005263936                                                           15    9605
XP_006711794                                                           15    9605
XP_005273085                                                           15    9605
XP_005273084                                                           15    9605
>NP_005148
          Length = 1130

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YLGIDLSQV 9
           Y GIDLSQV
Sbjct: 440 YPGIDLSQV 448
>NP_009297
          Length = 1149

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YLGIDLSQV 9
           Y GIDLSQV
Sbjct: 459 YPGIDLSQV 467
>NP_001161710
          Length = 1058

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YLGIDLSQV 9
           Y GIDLSQV
Sbjct: 465 YPGIDLSQV 473
>NP_001161709
          Length = 1079

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YLGIDLSQV 9
           Y GIDLSQV
Sbjct: 486 YPGIDLSQV 494
>NP_001161708
          Length = 1161

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YLGIDLSQV 9
           Y GIDLSQV
Sbjct: 465 YPGIDLSQV 473
>NP_009298
          Length = 1182

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YLGIDLSQV 9
           Y GIDLSQV
Sbjct: 486 YPGIDLSQV 494
>NP_001129473
          Length = 542

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YLGIDLSQV 9
           Y GIDLSQV
Sbjct: 465 YPGIDLSQV 473
>NP_005149
          Length = 1167

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YLGIDLSQV 9
           Y GIDLSQV
Sbjct: 471 YPGIDLSQV 479
>NP_001161711
          Length = 1043

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YLGIDLSQV 9
           Y GIDLSQV
Sbjct: 450 YPGIDLSQV 458
>XP_005245145
          Length = 1146

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YLGIDLSQV 9
           Y GIDLSQV
Sbjct: 450 YPGIDLSQV 458
>NP_001129472
          Length = 1064

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YLGIDLSQV 9
           Y GIDLSQV
Sbjct: 471 YPGIDLSQV 479
>NP_072089
          Length = 481

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   GIDLSQV 9
           G+DLSQV
Sbjct: 370 GLDLSQV 376
>NP_001273572
          Length = 361

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LGIDLSQV 9
           LG+DLS++
Sbjct: 162 LGVDLSKI 169
>NP_057026
          Length = 417

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LGIDLSQV 9
           LG+DLS++
Sbjct: 162 LGVDLSKI 169
>NP_001020016
          Length = 633

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   YLGIDLSQV 9
           +LG+D+S+V
Sbjct: 351 HLGVDVSRV 359
>NP_964012
          Length = 706

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   YLGIDLSQV 9
           +LG+D+S+V
Sbjct: 424 HLGVDVSRV 432
>NP_008865
          Length = 652

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   YLGIDLSQV 9
           +LG+D+S+V
Sbjct: 370 HLGVDVSRV 378
>NP_001248309
          Length = 637

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   YLGIDLSQV 9
           +LG+D+S+V
Sbjct: 355 HLGVDVSRV 363
>XP_005272689
          Length = 481

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   GIDLSQV 9
           G+DLSQV
Sbjct: 370 GLDLSQV 376
>XP_006716632
          Length = 296

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LGIDLSQV 9
          LG+DLS++
Sbjct: 41 LGVDLSKI 48
>XP_005250984
          Length = 296

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LGIDLSQV 9
          LG+DLS++
Sbjct: 41 LGVDLSKI 48
>XP_006716631
          Length = 304

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LGIDLSQV 9
          LG+DLS++
Sbjct: 49 LGVDLSKI 56
>XP_005250983
          Length = 417

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LGIDLSQV 9
           LG+DLS++
Sbjct: 162 LGVDLSKI 169
>XP_006710903
          Length = 649

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   YLGIDLSQV 9
           +LG+D+S+V
Sbjct: 424 HLGVDVSRV 432
>NP_055132
          Length = 415

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  GIDLSQV 9
          G+DLSQ+
Sbjct: 49 GLDLSQI 55
>NP_001009
          Length = 145

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  YLGIDLSQV 9
          Y G+DL Q+
Sbjct: 17 YRGVDLDQL 25
>NP_075048
          Length = 1088

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  YLGIDLSQ 8
          Y+G DL+Q
Sbjct: 19 YIGTDLTQ 26
>NP_001124397
          Length = 538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YLGIDLSQV 9
           Y G+DLS++
Sbjct: 146 YKGLDLSKL 154
>NP_055405
          Length = 538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YLGIDLSQV 9
           Y G+DLS++
Sbjct: 146 YKGLDLSKL 154
>NP_055906
          Length = 1720

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LGIDLSQV 9
           LG+DL++V
Sbjct: 249 LGLDLTEV 256
>NP_001171671
          Length = 672

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LGIDLSQV 9
           LG+ LSQV
Sbjct: 116 LGVPLSQV 123
>NP_006768
          Length = 672

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LGIDLSQV 9
           LG+ LSQV
Sbjct: 116 LGVPLSQV 123
>NP_001013652
          Length = 407

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   YLGIDLS 7
           YL IDLS
Sbjct: 256 YLAIDLS 262
>XP_006720146
          Length = 1226

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LGIDLSQV 9
           LG+DL++V
Sbjct: 249 LGLDLTEV 256
>XP_005267508
          Length = 1773

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LGIDLSQV 9
           LG+DL++V
Sbjct: 249 LGLDLTEV 256
>XP_006712074
          Length = 325

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  GIDLSQV 9
          G+D+SQV
Sbjct: 80 GVDVSQV 86
>XP_005264351
          Length = 344

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GIDLSQV 9
           G+D+SQV
Sbjct: 126 GVDVSQV 132
>XP_006712072
          Length = 370

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GIDLSQV 9
           G+D+SQV
Sbjct: 125 GVDVSQV 131
>XP_006712071
          Length = 371

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GIDLSQV 9
           G+D+SQV
Sbjct: 126 GVDVSQV 132
>XP_006710671
          Length = 340

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   YLGIDLS 7
           YL IDLS
Sbjct: 189 YLAIDLS 195
>NP_006479
          Length = 298

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  GIDLSQV 9
          G+D+SQV
Sbjct: 80 GVDVSQV 86
>NP_000072
          Length = 3801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    YLGIDLSQV 9
            Y G+D+S V
Sbjct: 3383 YFGMDVSAV 3391
>NP_001257903
          Length = 5121

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    YLGIDLS 7
            +LGID+S
Sbjct: 2019 HLGIDIS 2025
>NP_001159450
          Length = 834

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LGIDLSQV 9
           LG D SQV
Sbjct: 319 LGADFSQV 326
>NP_653308
          Length = 834

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LGIDLSQV 9
           LG D SQV
Sbjct: 319 LGADFSQV 326
>NP_001159449
          Length = 834

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LGIDLSQV 9
           LG D SQV
Sbjct: 319 LGADFSQV 326
>NP_001166104
          Length = 189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LGIDLSQV 9
          LG+ LSQV
Sbjct: 56 LGMQLSQV 63
>NP_001166103
          Length = 181

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LGIDLSQV 9
          LG+ LSQV
Sbjct: 56 LGMQLSQV 63
>NP_002534
          Length = 273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LGIDLSQV 9
          LG+ LSQV
Sbjct: 56 LGMQLSQV 63
>XP_006721269
          Length = 5138

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    YLGIDLS 7
            +LGID+S
Sbjct: 2036 HLGIDIS 2042
>XP_006719144
          Length = 217

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LGIDLSQV 9
          LG+ LSQV
Sbjct: 56 LGMQLSQV 63
>XP_005263937
          Length = 758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LGIDLSQV 9
           LG D SQV
Sbjct: 243 LGADFSQV 250
>XP_005263936
          Length = 834

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LGIDLSQV 9
           LG D SQV
Sbjct: 319 LGADFSQV 326
>XP_006711794
          Length = 3022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    YLGIDLSQV 9
            Y G+D+S V
Sbjct: 2604 YFGMDVSAV 2612
>XP_005273085
          Length = 3755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    YLGIDLSQV 9
            Y G+D+S V
Sbjct: 3337 YFGMDVSAV 3345
>XP_005273084
          Length = 3801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    YLGIDLSQV 9
            Y G+D+S V
Sbjct: 3383 YFGMDVSAV 3391
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.324    0.149    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 449,233
Number of extensions: 507
Number of successful extensions: 56
Number of sequences better than 10000.0: 56
Number of HSP's gapped: 56
Number of HSP's successfully gapped: 56
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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