Cancertope: In silico Platform for designing genome-based Personalized immunotherapy or Vaccine against Cancer

Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE

Protein	Neoepitopes	Tissue	Position	Prot Mutation	cDNA Mutation	Mutation Type	Num Mismatch	Promiscuity (%)	Cell Line	CTL	MHC I	NHLApred	MHC II	Bcell
Result		Search:
CBL	AGGGSGSGA	STOMACH	11	p.G18fs	c.52_52delG	Frame_Shift_Del	1	0.11	2313287	N	0	0	0	Y
CBL	CLGSEARSV	LUNG	634	p.M628fs	c.1883_1883delT	Frame_Shift_Del	5	0.11	VMRCLCP	Y	3	9	0	N
CBL	DQMCLGSEA	LUNG	631	p.M628fs	c.1883_1883delT	Frame_Shift_Del	5	0.11	VMRCLCP	N	1	0	0	N
CBL	EARSVWIPP	LUNG	638	p.M628fs	c.1883_1883delT	Frame_Shift_Del	6	0.11	VMRCLCP	N	0	0	0	N
CBL	FSLPSQRSP	LUNG	622	p.M628fs	c.1883_1883delT	Frame_Shift_Del	2	0.11	VMRCLCP	N	2	0	0	N
CBL	GGGSGSGAR	STOMACH	12	p.G18fs	c.52_52delG	Frame_Shift_Del	2	0.11	2313287	N	1	0	0	Y
CBL	GGSGSGARV	STOMACH	13	p.G18fs	c.52_52delG	Frame_Shift_Del	3	0.11	2313287	N	6	0	0	Y
CBL	GSEARSVWI	LUNG	636	p.M628fs	c.1883_1883delT	Frame_Shift_Del	6	0.11	VMRCLCP	N	4	0	0	N
CBL	GSGARVRVA	STOMACH	16	p.G18fs	c.52_52delG	Frame_Shift_Del	5	0.11	2313287	Y	1	11	0	N
CBL	GSGSGARVR	STOMACH	14	p.G18fs	c.52_52delG	Frame_Shift_Del	4	0.11	2313287	Y	3	9	0	N
CBL	LGSEARSVW	LUNG	635	p.M628fs	c.1883_1883delT	Frame_Shift_Del	6	0.11	VMRCLCP	N	3	0	0	N
CBL	LPFSLPSQR	LUNG	620	p.M628fs	c.1883_1883delT	Frame_Shift_Del	1	0.11	VMRCLCP	N	8	0	0	N
CBL	LPSQRSPDQ	LUNG	624	p.M628fs	c.1883_1883delT	Frame_Shift_Del	4	0.11	VMRCLCP	N	1	0	0	N
CBL	MCLGSEARS	LUNG	633	p.M628fs	c.1883_1883delT	Frame_Shift_Del	5	0.11	VMRCLCP	N	0	0	0	N
CBL	PDQMCLGSE	LUNG	630	p.M628fs	c.1883_1883delT	Frame_Shift_Del	4	0.11	VMRCLCP	N	0	0	0	N
CBL	PFSLPSQRS	LUNG	621	p.M628fs	c.1883_1883delT	Frame_Shift_Del	2	0.11	VMRCLCP	N	0	0	0	N
CBL	PSQRSPDQM	LUNG	625	p.M628fs	c.1883_1883delT	Frame_Shift_Del	5	0.11	VMRCLCP	N	0	0	0	N
CBL	QMCLGSEAR	LUNG	632	p.M628fs	c.1883_1883delT	Frame_Shift_Del	6	0.11	VMRCLCP	N	6	0	0	N
CBL	QRSPDQMCL	LUNG	627	p.M628fs	c.1883_1883delT	Frame_Shift_Del	5	0.11	VMRCLCP	N	6	0	0	N
CBL	RSPDQMCLG	LUNG	628	p.M628fs	c.1883_1883delT	Frame_Shift_Del	5	0.11	VMRCLCP	N	0	0	0	N
CBL	SEARSVWIP	LUNG	637	p.M628fs	c.1883_1883delT	Frame_Shift_Del	6	0.11	VMRCLCP	N	1	0	0	N
CBL	SGSGARVRV	STOMACH	15	p.G18fs	c.52_52delG	Frame_Shift_Del	5	0.11	2313287	Y	4	10	0	N
CBL	SLPSQRSPD	LUNG	623	p.M628fs	c.1883_1883delT	Frame_Shift_Del	3	0.11	VMRCLCP	N	0	0	0	N
CBL	SPDQMCLGS	LUNG	629	p.M628fs	c.1883_1883delT	Frame_Shift_Del	4	0.11	VMRCLCP	N	2	0	0	N
CBL	SQRSPDQMC	LUNG	626	p.M628fs	c.1883_1883delT	Frame_Shift_Del	5	0.11	VMRCLCP	N	2	0	0	N
CBL	AASAATALP	BREAST	847	p.S854L	c.2561C>T	Missense_Mutation	1	0.11	MDAMB415	N	0	0	0	N
CBL	AASDSLHKD	ENDOMETRIUM	522	p.G525D	c.1574G>A	Missense_Mutation	1	0.11	HEC1A	N	0	0	0	N
CBL	AATALPQLS	BREAST	850	p.S854L	c.2561C>T	Missense_Mutation	1	0.11	MDAMB415	N	1	0	0	N
CBL	AEPIVVDPF	OVARY	426	p.T426A	c.1276A>G	Missense_Mutation	1	0.11	IGROV1	N	8	0	0	N
CBL	ALHEVHLIS	OESOPHAGUS	208	p.P214L	c.641C>T	Missense_Mutation	1	0.11	KYSE180	N	0	0	0	N
CBL	ALKSTIVLT	LARGE_INTESTINE	223	p.D229V	c.686A>T	Missense_Mutation	1	0.11	SNU175	N	1	0	0	N
CBL	ALLARRTLS	LUNG	783	p.V784L	c.2350G>T	Missense_Mutation	1	0.11	NCIH2342	N	1	0	0	N
CBL	ALPQLSSEI	BREAST	853	p.S854L	c.2561C>T	Missense_Mutation	1	0.11	MDAMB415	Y	8	11	0	N
CBL	AMALKSTIV	LARGE_INTESTINE	221	p.D229V	c.686A>T	Missense_Mutation	1	0.11	SNU175	N	6	0	0	N
CBL	AMLARRTLS	ENDOMETRIUM	783	p.V784M	c.2350G>A	Missense_Mutation	1	0.11	RL952	N	1	0	0	Y
CBL	AQNNIEMVK	ENDOMETRIUM	881	p.A888V	c.2663C>T	Missense_Mutation	1	0.11	HEC108	Y	4	17	0	N
CBL	ARRTLSDIF	UPPER_AERODIGESTIVE_TRACT	786	p.S794F	c.2381C>T	Missense_Mutation	1	0.11	SNU1041	N	3	0	0	N
CBL	ARRTLSHIS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	786	p.D792H	c.2374G>C	Missense_Mutation	1	0.11	K562	N	2	0	0	N
CBL	ASAATALPQ	BREAST	848	p.S854L	c.2561C>T	Missense_Mutation	1	0.11	MDAMB415	N	0	0	0	N
CBL	ASDSLHKDK	ENDOMETRIUM	523	p.G525D	c.1574G>A	Missense_Mutation	1	0.11	HEC1A	N	2	0	0	N
CBL	ASKAASDSL	ENDOMETRIUM	519	p.G525D	c.1574G>A	Missense_Mutation	1	0.11	HEC1A	N	6	0	0	N
CBL	ASLPPVPPQ	LARGE_INTESTINE	491	p.R499Q	c.1496G>A	Missense_Mutation	1	0.11	SNU81	N	0	0	0	Y
CBL	ATALPQLSS	BREAST	851	p.S854L	c.2561C>T	Missense_Mutation	1	0.11	MDAMB415	N	0	0	0	N
CBL	AVHEVHPIS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	208	p.L209V	c.625C>G	Missense_Mutation	1	0.11	BDCM	N	0	0	0	N
CBL	CEIKGAEPI	OVARY	421	p.T426A	c.1276A>G	Missense_Mutation	1	0.11	IGROV1	N	7	0	0	N
CBL	CEITGTEPI	LUNG	421	p.K424T	c.1271A>C	Missense_Mutation	1	0.11	NCIH2029	N	6	0	0	N
CBL	CGHLMCTFC	LARGE_INTESTINE	396	p.S403F	c.1208C>T	Missense_Mutation	1	0.11	HCT15	N	1	0	0	N
CBL	CGLEAMALK	CENTRAL_NERVOUS_SYSTEM	217	p.S217C	c.650C>G	Missense_Mutation	1	0.11	KS1	N	0	0	0	N
CBL	CLGDSWLPR	LUNG	585	p.R585C	c.1753C>T	Missense_Mutation	1	0.11	A549	N	6	0	0	N
CBL	CPFCQCEIK	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	416	p.R420Q	c.1259G>A	Missense_Mutation	1	0.11	GDM1	N	4	0	0	N
CBL	CPFCRCEIT	LUNG	416	p.K424T	c.1271A>C	Missense_Mutation	1	0.11	NCIH2029	N	8	0	0	N
CBL	CQCEIKGTE	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	419	p.R420Q	c.1259G>A	Missense_Mutation	1	0.11	GDM1	N	0	0	0	N
CBL	CRCEIKGAE	OVARY	419	p.T426A	c.1276A>G	Missense_Mutation	1	0.11	IGROV1	N	1	0	0	N
CBL	CRCEITGTE	LUNG	419	p.K424T	c.1271A>C	Missense_Mutation	1	0.11	NCIH2029	N	1	0	0	N
CBL	CTFCLTSWQ	LARGE_INTESTINE	401	p.S403F	c.1208C>T	Missense_Mutation	1	0.11	HCT15	N	0	0	0	N
CBL	DEGYDVPKP	LUNG	771	p.D772E	c.2316T>G	Missense_Mutation	1	0.11	ABC1	N	1	0	0	N
CBL	DGDHTTNVT	LARGE_INTESTINE	806	p.P809H	c.2426C>A	Missense_Mutation	1	0.11	CW2	N	3	0	0	N
CBL	DHTTNVTEG	LARGE_INTESTINE	808	p.P809H	c.2426C>A	Missense_Mutation	1	0.11	CW2	N	0	0	0	N
CBL	DIFNASSSF	UPPER_AERODIGESTIVE_TRACT	792	p.S794F	c.2381C>T	Missense_Mutation	1	0.11	SNU1041	N	4	0	0	Y
CBL	DISTASSSF	STOMACH	792	p.N795T	c.2384A>C	Missense_Mutation	1	0.11	SNU719	N	2	0	0	Y
CBL	DKKMVENCW	ENDOMETRIUM	52	p.K58N	c.174G>T	Missense_Mutation	1	0.11	HEC6	N	1	0	0	N
CBL	DSLHKDKPL	ENDOMETRIUM	525	p.G525D	c.1574G>A	Missense_Mutation	1	0.11	HEC1A	N	12	0	0	N
CBL	EDEGYDVPK	LUNG	770	p.D772E	c.2316T>G	Missense_Mutation	1	0.11	ABC1	N	1	0	0	Y
CBL	EENSQPRQN	LARGE_INTESTINE	142	p.R149Q	c.446G>A	Missense_Mutation	1	0.11	HT115	N	3	0	0	N
CBL	EESENEDEG	LUNG	765	p.D772E	c.2316T>G	Missense_Mutation	1	0.11	ABC1	N	0	0	0	N
CBL	EGQGCPFCQ	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	412	p.R420Q	c.1259G>A	Missense_Mutation	1	0.11	GDM1	N	0	0	0	N
CBL	EGYDVPKPP	LUNG	772	p.D772E	c.2316T>G	Missense_Mutation	1	0.11	ABC1	N	0	0	0	N
CBL	EIKGAEPIV	OVARY	422	p.T426A	c.1276A>G	Missense_Mutation	1	0.11	IGROV1	N	3	0	0	N
CBL	EITGTEPIV	LUNG	422	p.K424T	c.1271A>C	Missense_Mutation	1	0.11	NCIH2029	N	3	0	0	N
CBL	EMVKNILRE	ENDOMETRIUM	886	p.A888V	c.2663C>T	Missense_Mutation	1	0.11	HEC108	N	0	0	0	N
CBL	ENCWKLMDK	ENDOMETRIUM	57	p.K58N	c.174G>T	Missense_Mutation	1	0.11	HEC6	N	0	0	0	N
CBL	ENEDEGYDV	LUNG	768	p.D772E	c.2316T>G	Missense_Mutation	1	0.11	ABC1	N	1	0	0	N
CBL	ENSQPRQNL	LARGE_INTESTINE	143	p.R149Q	c.446G>A	Missense_Mutation	1	0.11	HT115	Y	4	17	0	N
CBL	ESENEDEGY	LUNG	766	p.D772E	c.2316T>G	Missense_Mutation	1	0.11	ABC1	N	4	0	0	N
CBL	EVHLISSGL	OESOPHAGUS	211	p.P214L	c.641C>T	Missense_Mutation	1	0.11	KYSE180	N	8	0	0	N
CBL	EVHPISCGL	CENTRAL_NERVOUS_SYSTEM	211	p.S217C	c.650C>G	Missense_Mutation	1	0.11	KS1	N	10	0	0	N
CBL	FCLTSWQES	LARGE_INTESTINE	403	p.S403F	c.1208C>T	Missense_Mutation	1	0.11	HCT15	N	2	0	0	N
CBL	FCQCEIKGT	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	418	p.R420Q	c.1259G>A	Missense_Mutation	1	0.11	GDM1	N	2	0	0	N
CBL	FCRCEIKGA	OVARY	418	p.T426A	c.1276A>G	Missense_Mutation	1	0.11	IGROV1	N	4	0	4	N
CBL	FCRCEITGT	LUNG	418	p.K424T	c.1271A>C	Missense_Mutation	1	0.11	NCIH2029	N	2	0	0	N
CBL	FNASSSFGW	UPPER_AERODIGESTIVE_TRACT	794	p.S794F	c.2381C>T	Missense_Mutation	1	0.11	SNU1041	N	3	0	2	N
CBL	FRQAVHEVH	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	205	p.L209V	c.625C>G	Missense_Mutation	1	0.11	BDCM	N	4	0	1	N
CBL	GAEPIVVDP	OVARY	425	p.T426A	c.1276A>G	Missense_Mutation	1	0.11	IGROV1	N	1	0	0	N
CBL	GCPFCQCEI	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	415	p.R420Q	c.1259G>A	Missense_Mutation	1	0.11	GDM1	Y	2	9	0	N
CBL	GDHTTNVTE	LARGE_INTESTINE	807	p.P809H	c.2426C>A	Missense_Mutation	1	0.11	CW2	N	0	0	0	N
CBL	GHLMCTFCL	LARGE_INTESTINE	397	p.S403F	c.1208C>T	Missense_Mutation	1	0.11	HCT15	N	7	0	0	N
CBL	GQGCPFCQC	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	413	p.R420Q	c.1259G>A	Missense_Mutation	1	0.11	GDM1	N	2	0	0	N
CBL	GTASKAASD	ENDOMETRIUM	517	p.G525D	c.1574G>A	Missense_Mutation	1	0.11	HEC1A	N	0	0	0	N
CBL	GWLSLDGDH	LARGE_INTESTINE	801	p.P809H	c.2426C>A	Missense_Mutation	1	0.11	CW2	N	0	0	0	N
CBL	HEVHLISSG	OESOPHAGUS	210	p.P214L	c.641C>T	Missense_Mutation	1	0.11	KYSE180	N	2	0	0	N
CBL	HEVHPISCG	CENTRAL_NERVOUS_SYSTEM	210	p.S217C	c.650C>G	Missense_Mutation	1	0.11	KS1	N	2	0	0	N
CBL	HISNASSSF	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	792	p.D792H	c.2374G>C	Missense_Mutation	1	0.11	K562	N	3	0	0	N
CBL	HLISSGLEA	OESOPHAGUS	213	p.P214L	c.641C>T	Missense_Mutation	1	0.11	KYSE180	N	3	0	0	N
CBL	HLMCTFCLT	LARGE_INTESTINE	398	p.S403F	c.1208C>T	Missense_Mutation	1	0.11	HCT15	N	4	0	0	N
CBL	HPISCGLEA	CENTRAL_NERVOUS_SYSTEM	213	p.S217C	c.650C>G	Missense_Mutation	1	0.11	KS1	N	9	0	0	N
CBL	HTTNVTEGS	LARGE_INTESTINE	809	p.P809H	c.2426C>A	Missense_Mutation	1	0.11	CW2	N	0	0	0	N
CBL	IAQNNIEMV	ENDOMETRIUM	880	p.A888V	c.2663C>T	Missense_Mutation	1	0.11	HEC108	N	9	0	0	N
CBL	IEMVKNILR	ENDOMETRIUM	885	p.A888V	c.2663C>T	Missense_Mutation	1	0.11	HEC108	N	0	0	5	N
CBL	IFNASSSFG	UPPER_AERODIGESTIVE_TRACT	793	p.S794F	c.2381C>T	Missense_Mutation	1	0.11	SNU1041	N	0	0	4	N
CBL	IKGAEPIVV	OVARY	423	p.T426A	c.1276A>G	Missense_Mutation	1	0.11	IGROV1	N	3	0	4	N
CBL	ISCGLEAMA	CENTRAL_NERVOUS_SYSTEM	215	p.S217C	c.650C>G	Missense_Mutation	1	0.11	KS1	N	3	0	0	N
CBL	ISTASSSFG	STOMACH	793	p.N795T	c.2384A>C	Missense_Mutation	1	0.11	SNU719	N	0	0	0	Y
CBL	ITGTEPIVV	LUNG	423	p.K424T	c.1271A>C	Missense_Mutation	1	0.11	NCIH2029	Y	4	11	2	N
CBL	IVLTCNDYI	LARGE_INTESTINE	228	p.D229V	c.686A>T	Missense_Mutation	1	0.11	SNU175	Y	13	11	9	N
CBL	KAASDSLHK	ENDOMETRIUM	521	p.G525D	c.1574G>A	Missense_Mutation	1	0.11	HEC1A	N	4	0	0	N
CBL	KGAEPIVVD	OVARY	424	p.T426A	c.1276A>G	Missense_Mutation	1	0.11	IGROV1	N	0	0	0	N
CBL	KKMVENCWK	ENDOMETRIUM	53	p.K58N	c.174G>T	Missense_Mutation	1	0.11	HEC6	N	1	0	0	N
CBL	KLPPVPSSC	LUNG	577	p.R585C	c.1753C>T	Missense_Mutation	1	0.11	A549	N	4	0	0	N
CBL	KMVENCWKL	ENDOMETRIUM	54	p.K58N	c.174G>T	Missense_Mutation	1	0.11	HEC6	Y	19	9	0	N
CBL	KPPVPALLA	LUNG	778	p.V784L	c.2350G>T	Missense_Mutation	1	0.11	NCIH2342	N	9	0	0	N
CBL	KPPVPAMLA	ENDOMETRIUM	778	p.V784M	c.2350G>A	Missense_Mutation	1	0.11	RL952	N	9	0	0	N
CBL	KSFRQAVHE	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	203	p.L209V	c.625C>G	Missense_Mutation	1	0.11	BDCM	N	0	0	0	N
CBL	KSTIVLTCN	LARGE_INTESTINE	225	p.D229V	c.686A>T	Missense_Mutation	1	0.11	SNU175	N	1	0	0	N
CBL	LARRTLSHI	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	785	p.D792H	c.2374G>C	Missense_Mutation	1	0.11	K562	Y	9	11	2	Y
CBL	LDGDHTTNV	LARGE_INTESTINE	805	p.P809H	c.2426C>A	Missense_Mutation	1	0.11	CW2	N	4	0	0	N
CBL	LHEVHLISS	OESOPHAGUS	209	p.P214L	c.641C>T	Missense_Mutation	1	0.11	KYSE180	N	2	0	0	N
CBL	LHEVHPISC	CENTRAL_NERVOUS_SYSTEM	209	p.S217C	c.650C>G	Missense_Mutation	1	0.11	KS1	N	2	0	0	N
CBL	LISSGLEAM	OESOPHAGUS	214	p.P214L	c.641C>T	Missense_Mutation	1	0.11	KYSE180	N	3	0	1	N
CBL	LKSTIVLTC	LARGE_INTESTINE	224	p.D229V	c.686A>T	Missense_Mutation	1	0.11	SNU175	N	1	0	20	N
CBL	LLARRTLSD	LUNG	784	p.V784L	c.2350G>T	Missense_Mutation	1	0.11	NCIH2342	N	0	0	8	N
CBL	LMCTFCLTS	LARGE_INTESTINE	399	p.S403F	c.1208C>T	Missense_Mutation	1	0.11	HCT15	N	1	0	8	N
CBL	LPPVPPQLD	LARGE_INTESTINE	493	p.R499Q	c.1496G>A	Missense_Mutation	1	0.11	SNU81	N	1	0	0	Y
CBL	LPPVPSSCL	LUNG	578	p.R585C	c.1753C>T	Missense_Mutation	1	0.11	A549	N	19	0	2	N
CBL	LPQLSSEIE	BREAST	854	p.S854L	c.2561C>T	Missense_Mutation	1	0.11	MDAMB415	N	1	0	0	N
CBL	LSDIFNASS	UPPER_AERODIGESTIVE_TRACT	790	p.S794F	c.2381C>T	Missense_Mutation	1	0.11	SNU1041	N	1	0	0	N
CBL	LSDISTASS	STOMACH	790	p.N795T	c.2384A>C	Missense_Mutation	1	0.11	SNU719	N	1	0	2	N
CBL	LSHISNASS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	790	p.D792H	c.2374G>C	Missense_Mutation	1	0.11	K562	N	0	0	8	N
CBL	LSLDGDHTT	LARGE_INTESTINE	803	p.P809H	c.2426C>A	Missense_Mutation	1	0.11	CW2	N	1	0	0	N
CBL	MALKSTIVL	LARGE_INTESTINE	222	p.D229V	c.686A>T	Missense_Mutation	1	0.11	SNU175	N	19	0	9	N
CBL	MCTFCLTSW	LARGE_INTESTINE	400	p.S403F	c.1208C>T	Missense_Mutation	1	0.11	HCT15	N	3	0	0	N
CBL	MLARRTLSD	ENDOMETRIUM	784	p.V784M	c.2350G>A	Missense_Mutation	1	0.11	RL952	N	0	0	8	N
CBL	MVENCWKLM	ENDOMETRIUM	55	p.K58N	c.174G>T	Missense_Mutation	1	0.11	HEC6	N	2	0	0	N
CBL	MVKNILREF	ENDOMETRIUM	887	p.A888V	c.2663C>T	Missense_Mutation	1	0.11	HEC108	N	4	0	11	N
CBL	NCWKLMDKV	ENDOMETRIUM	58	p.K58N	c.174G>T	Missense_Mutation	1	0.11	HEC6	N	6	0	0	N
CBL	NEDEGYDVP	LUNG	769	p.D772E	c.2316T>G	Missense_Mutation	1	0.11	ABC1	N	0	0	0	N
CBL	NIEMVKNIL	ENDOMETRIUM	884	p.A888V	c.2663C>T	Missense_Mutation	1	0.11	HEC108	Y	6	10	0	N
CBL	NNIEMVKNI	ENDOMETRIUM	883	p.A888V	c.2663C>T	Missense_Mutation	1	0.11	HEC108	Y	7	14	0	N
CBL	NSQPRQNLT	LARGE_INTESTINE	144	p.R149Q	c.446G>A	Missense_Mutation	1	0.11	HT115	N	1	0	0	N
CBL	PAASAATAL	BREAST	846	p.S854L	c.2561C>T	Missense_Mutation	1	0.11	MDAMB415	N	1	0	0	N
CBL	PALLARRTL	LUNG	782	p.V784L	c.2350G>T	Missense_Mutation	1	0.11	NCIH2342	N	3	0	0	N
CBL	PAMLARRTL	ENDOMETRIUM	782	p.V784M	c.2350G>A	Missense_Mutation	1	0.11	RL952	N	3	0	0	N
CBL	PCGHLMCTF	LARGE_INTESTINE	395	p.S403F	c.1208C>T	Missense_Mutation	1	0.11	HCT15	N	0	0	0	N
CBL	PEESENEDE	LUNG	764	p.D772E	c.2316T>G	Missense_Mutation	1	0.11	ABC1	N	0	0	0	N
CBL	PFCQCEIKG	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	417	p.R420Q	c.1259G>A	Missense_Mutation	1	0.11	GDM1	N	0	0	0	N
CBL	PFCRCEITG	LUNG	417	p.K424T	c.1271A>C	Missense_Mutation	1	0.11	NCIH2029	N	0	0	0	N
CBL	PISCGLEAM	CENTRAL_NERVOUS_SYSTEM	214	p.S217C	c.650C>G	Missense_Mutation	1	0.11	KS1	N	0	0	0	N
CBL	PKPPVPALL	LUNG	777	p.V784L	c.2350G>T	Missense_Mutation	1	0.11	NCIH2342	N	3	0	0	N
CBL	PKPPVPAML	ENDOMETRIUM	777	p.V784M	c.2350G>A	Missense_Mutation	1	0.11	RL952	N	3	0	0	N
CBL	PPQLDLLPQ	LARGE_INTESTINE	497	p.R499Q	c.1496G>A	Missense_Mutation	1	0.11	SNU81	N	0	0	0	Y
CBL	PPVPALLAR	LUNG	779	p.V784L	c.2350G>T	Missense_Mutation	1	0.11	NCIH2342	N	0	0	0	N
CBL	PPVPAMLAR	ENDOMETRIUM	779	p.V784M	c.2350G>A	Missense_Mutation	1	0.11	RL952	N	0	0	0	N
CBL	PPVPPQLDL	LARGE_INTESTINE	494	p.R499Q	c.1496G>A	Missense_Mutation	1	0.11	SNU81	N	11	0	0	Y
CBL	PPVPSSCLG	LUNG	579	p.R585C	c.1753C>T	Missense_Mutation	1	0.11	A549	N	0	0	0	Y
CBL	PQLDLLPQR	LARGE_INTESTINE	498	p.R499Q	c.1496G>A	Missense_Mutation	1	0.11	SNU81	N	1	0	0	N
CBL	PRQNLTKLS	LARGE_INTESTINE	147	p.R149Q	c.446G>A	Missense_Mutation	1	0.11	HT115	N	0	0	0	N
CBL	PSSCLGDSW	LUNG	582	p.R585C	c.1753C>T	Missense_Mutation	1	0.11	A549	N	1	0	0	N
CBL	PVPALLARR	LUNG	780	p.V784L	c.2350G>T	Missense_Mutation	1	0.11	NCIH2342	N	3	0	0	Y
CBL	PVPAMLARR	ENDOMETRIUM	780	p.V784M	c.2350G>A	Missense_Mutation	1	0.11	RL952	N	3	0	0	N
CBL	PVPPQLDLL	LARGE_INTESTINE	495	p.R499Q	c.1496G>A	Missense_Mutation	1	0.11	SNU81	N	1	0	0	N
CBL	PVPSSCLGD	LUNG	580	p.R585C	c.1753C>T	Missense_Mutation	1	0.11	A549	N	0	0	0	N
CBL	PWKSFRQAV	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	201	p.L209V	c.625C>G	Missense_Mutation	1	0.11	BDCM	N	2	0	0	N
CBL	QALHEVHLI	OESOPHAGUS	207	p.P214L	c.641C>T	Missense_Mutation	1	0.11	KYSE180	Y	10	11	0	N
CBL	QAVHEVHPI	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	207	p.L209V	c.625C>G	Missense_Mutation	1	0.11	BDCM	N	9	0	0	N
CBL	QCEIKGTEP	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	420	p.R420Q	c.1259G>A	Missense_Mutation	1	0.11	GDM1	N	0	0	0	N
CBL	QGCPFCQCE	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	414	p.R420Q	c.1259G>A	Missense_Mutation	1	0.11	GDM1	N	0	0	0	N
CBL	QLDLLPQRV	LARGE_INTESTINE	499	p.R499Q	c.1496G>A	Missense_Mutation	1	0.11	SNU81	Y	4	12	0	N
CBL	QNLTKLSLI	LARGE_INTESTINE	149	p.R149Q	c.446G>A	Missense_Mutation	1	0.11	HT115	N	6	0	0	N
CBL	QNNIEMVKN	ENDOMETRIUM	882	p.A888V	c.2663C>T	Missense_Mutation	1	0.11	HEC108	N	0	0	0	N
CBL	QPRQNLTKL	LARGE_INTESTINE	146	p.R149Q	c.446G>A	Missense_Mutation	1	0.11	HT115	Y	15	13	0	N
CBL	RCEIKGAEP	OVARY	420	p.T426A	c.1276A>G	Missense_Mutation	1	0.11	IGROV1	N	0	0	0	N
CBL	RCEITGTEP	LUNG	420	p.K424T	c.1271A>C	Missense_Mutation	1	0.11	NCIH2029	N	0	0	0	N
CBL	RQALHEVHL	OESOPHAGUS	206	p.P214L	c.641C>T	Missense_Mutation	1	0.11	KYSE180	Y	11	10	0	N
CBL	RQAVHEVHP	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	206	p.L209V	c.625C>G	Missense_Mutation	1	0.11	BDCM	N	0	0	0	N
CBL	RQNLTKLSL	LARGE_INTESTINE	148	p.R149Q	c.446G>A	Missense_Mutation	1	0.11	HT115	Y	12	15	0	N
CBL	RRTLSDIFN	UPPER_AERODIGESTIVE_TRACT	787	p.S794F	c.2381C>T	Missense_Mutation	1	0.11	SNU1041	N	2	0	0	N
CBL	RRTLSDIST	STOMACH	787	p.N795T	c.2384A>C	Missense_Mutation	1	0.11	SNU719	N	2	0	0	N
CBL	RRTLSHISN	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	787	p.D792H	c.2374G>C	Missense_Mutation	1	0.11	K562	N	2	0	0	N
CBL	RTLSDIFNA	UPPER_AERODIGESTIVE_TRACT	788	p.S794F	c.2381C>T	Missense_Mutation	1	0.11	SNU1041	Y	7	9	0	N
CBL	RTLSDISTA	STOMACH	788	p.N795T	c.2384A>C	Missense_Mutation	1	0.11	SNU719	Y	3	10	0	N
CBL	RTLSHISNA	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	788	p.D792H	c.2374G>C	Missense_Mutation	1	0.11	K562	Y	3	11	0	N
CBL	SAATALPQL	BREAST	849	p.S854L	c.2561C>T	Missense_Mutation	1	0.11	MDAMB415	Y	11	9	0	N
CBL	SCGLEAMAL	CENTRAL_NERVOUS_SYSTEM	216	p.S217C	c.650C>G	Missense_Mutation	1	0.11	KS1	N	4	0	0	N
CBL	SCLGDSWLP	LUNG	584	p.R585C	c.1753C>T	Missense_Mutation	1	0.11	A549	N	0	0	0	N
CBL	SDIFNASSS	UPPER_AERODIGESTIVE_TRACT	791	p.S794F	c.2381C>T	Missense_Mutation	1	0.11	SNU1041	N	4	0	0	Y
CBL	SDISTASSS	STOMACH	791	p.N795T	c.2384A>C	Missense_Mutation	1	0.11	SNU719	N	3	0	0	Y
CBL	SDSLHKDKP	ENDOMETRIUM	524	p.G525D	c.1574G>A	Missense_Mutation	1	0.11	HEC1A	N	0	0	0	N
CBL	SENEDEGYD	LUNG	767	p.D772E	c.2316T>G	Missense_Mutation	1	0.11	ABC1	N	0	0	0	N
CBL	SFRQAVHEV	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	204	p.L209V	c.625C>G	Missense_Mutation	1	0.11	BDCM	Y	2	9	0	N
CBL	SHISNASSS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	791	p.D792H	c.2374G>C	Missense_Mutation	1	0.11	K562	N	3	0	0	N
CBL	SKAASDSLH	ENDOMETRIUM	520	p.G525D	c.1574G>A	Missense_Mutation	1	0.11	HEC1A	N	1	0	0	N
CBL	SLDGDHTTN	LARGE_INTESTINE	804	p.P809H	c.2426C>A	Missense_Mutation	1	0.11	CW2	N	0	0	0	N
CBL	SLPPVPPQL	LARGE_INTESTINE	492	p.R499Q	c.1496G>A	Missense_Mutation	1	0.11	SNU81	Y	17	11	0	Y
CBL	SQPRQNLTK	LARGE_INTESTINE	145	p.R149Q	c.446G>A	Missense_Mutation	1	0.11	HT115	N	4	0	0	N
CBL	SSCLGDSWL	LUNG	583	p.R585C	c.1753C>T	Missense_Mutation	1	0.11	A549	N	7	0	0	N
CBL	STASSSFGW	STOMACH	794	p.N795T	c.2384A>C	Missense_Mutation	1	0.11	SNU719	N	2	0	0	N
CBL	STIVLTCND	LARGE_INTESTINE	226	p.D229V	c.686A>T	Missense_Mutation	1	0.11	SNU175	N	0	0	0	N
CBL	TALPQLSSE	BREAST	852	p.S854L	c.2561C>T	Missense_Mutation	1	0.11	MDAMB415	N	0	0	0	N
CBL	TASKAASDS	ENDOMETRIUM	518	p.G525D	c.1574G>A	Missense_Mutation	1	0.11	HEC1A	N	1	0	0	N
CBL	TASSSFGWL	STOMACH	795	p.N795T	c.2384A>C	Missense_Mutation	1	0.11	SNU719	N	12	0	0	N
CBL	TFCLTSWQE	LARGE_INTESTINE	402	p.S403F	c.1208C>T	Missense_Mutation	1	0.11	HCT15	N	0	0	0	N
CBL	TGTEPIVVD	LUNG	424	p.K424T	c.1271A>C	Missense_Mutation	1	0.11	NCIH2029	N	0	0	0	N
CBL	TIVLTCNDY	LARGE_INTESTINE	227	p.D229V	c.686A>T	Missense_Mutation	1	0.11	SNU175	N	4	0	0	N
CBL	TLSDIFNAS	UPPER_AERODIGESTIVE_TRACT	789	p.S794F	c.2381C>T	Missense_Mutation	1	0.11	SNU1041	Y	0	11	0	N
CBL	TLSDISTAS	STOMACH	789	p.N795T	c.2384A>C	Missense_Mutation	1	0.11	SNU719	N	0	0	0	N
CBL	TLSHISNAS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	789	p.D792H	c.2374G>C	Missense_Mutation	1	0.11	K562	N	0	0	0	N
CBL	TVDKKMVEN	ENDOMETRIUM	50	p.K58N	c.174G>T	Missense_Mutation	1	0.11	HEC6	N	0	0	0	N
CBL	VDKKMVENC	ENDOMETRIUM	51	p.K58N	c.174G>T	Missense_Mutation	1	0.11	HEC6	N	3	0	0	N
CBL	VENCWKLMD	ENDOMETRIUM	56	p.K58N	c.174G>T	Missense_Mutation	1	0.11	HEC6	N	0	0	4	N
CBL	VHEVHPISS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	209	p.L209V	c.625C>G	Missense_Mutation	1	0.11	BDCM	N	2	0	3	N
CBL	VHLISSGLE	OESOPHAGUS	212	p.P214L	c.641C>T	Missense_Mutation	1	0.11	KYSE180	N	0	0	5	N
CBL	VHPISCGLE	CENTRAL_NERVOUS_SYSTEM	212	p.S217C	c.650C>G	Missense_Mutation	1	0.11	KS1	N	0	0	0	N
CBL	VKNILREFV	ENDOMETRIUM	888	p.A888V	c.2663C>T	Missense_Mutation	1	0.11	HEC108	N	3	0	6	N
CBL	VLARRTLSH	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	784	p.D792H	c.2374G>C	Missense_Mutation	1	0.11	K562	N	0	0	18	N
CBL	VLTCNDYIS	LARGE_INTESTINE	229	p.D229V	c.686A>T	Missense_Mutation	1	0.11	SNU175	N	1	0	0	N
CBL	VPALLARRT	LUNG	781	p.V784L	c.2350G>T	Missense_Mutation	1	0.11	NCIH2342	N	5	0	0	N
CBL	VPAMLARRT	ENDOMETRIUM	781	p.V784M	c.2350G>A	Missense_Mutation	1	0.11	RL952	N	5	0	0	N
CBL	VPKPPVPAL	LUNG	776	p.V784L	c.2350G>T	Missense_Mutation	1	0.11	NCIH2342	Y	14	11	0	N
CBL	VPKPPVPAM	ENDOMETRIUM	776	p.V784M	c.2350G>A	Missense_Mutation	1	0.11	RL952	Y	12	11	0	N
CBL	VPPQLDLLP	LARGE_INTESTINE	496	p.R499Q	c.1496G>A	Missense_Mutation	1	0.11	SNU81	N	2	0	0	N
CBL	VPSSCLGDS	LUNG	581	p.R585C	c.1753C>T	Missense_Mutation	1	0.11	A549	N	5	0	0	N
CBL	WKSFRQAVH	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	202	p.L209V	c.625C>G	Missense_Mutation	1	0.11	BDCM	N	3	0	9	N
CBL	WLSLDGDHT	LARGE_INTESTINE	802	p.P809H	c.2426C>A	Missense_Mutation	1	0.11	CW2	N	3	0	0	N
CBL	YEENSQPRQ	LARGE_INTESTINE	141	p.R149Q	c.446G>A	Missense_Mutation	1	0.11	HT115	N	2	0	0	N