Cancertope: In silico Platform for designing genome-based Personalized immunotherapy or Vaccine against Cancer

Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE

Protein	Neoepitopes	Tissue	Position	Prot Mutation	cDNA Mutation	Mutation Type	Num Mismatch	Promiscuity (%)	Cell Line	CTL	MHC I	NHLApred	MHC II	Bcell
Result		Search:
MSH2	AFIPNDVTL	ENDOMETRIUM	649	p.Y656fs	c.1966_1966delT	Frame_Shift_Del	2	0.11	HEC108	Y	8	10	0	N
MSH2	APIWEVNQH	ENDOMETRIUM	669	p.Y656fs	c.1966_1966delT	Frame_Shift_Del	6	0.11	HEC108	N	0	0	0	N
MSH2	ATHFHELSL	SOFT_TISSUE	781	p.T788fs	c.2363_2364delCT	Frame_Shift_Del	2	0.11	SKUT1	Y	6	12	0	N
MSH2	CSTSLLAPI	ENDOMETRIUM	663	p.Y656fs	c.1966_1966delT	Frame_Shift_Del	5	0.11	HEC108	N	5	0	0	N
MSH2	DTTGSQSGC	ENDOMETRIUM	319	p.S325fs	c.973_974delTC	Frame_Shift_Del	2	0.11	JHUEM1	N	0	0	0	N
MSH2	DVTLKKINR	ENDOMETRIUM	654	p.Y656fs	c.1966_1966delT	Frame_Shift_Del	5	0.11	HEC108	Y	5	9	0	N
MSH2	EDTTGSQSG	ENDOMETRIUM	318	p.S325fs	c.973_974delTC	Frame_Shift_Del	1	0.11	JHUEM1	N	0	0	0	N
MSH2	ELSLGQSDT	SOFT_TISSUE	786	p.T788fs	c.2363_2364delCT	Frame_Shift_Del	5	0.11	SKUT1	N	1	0	0	N
MSH2	EVNQHIFDK	ENDOMETRIUM	673	p.Y656fs	c.1966_1966delT	Frame_Shift_Del	5	0.11	HEC108	Y	5	11	0	N
MSH2	FATHFHELS	SOFT_TISSUE	780	p.T788fs	c.2363_2364delCT	Frame_Shift_Del	1	0.11	SKUT1	N	3	0	0	N
MSH2	FHELSLGQS	SOFT_TISSUE	784	p.T788fs	c.2363_2364delCT	Frame_Shift_Del	5	0.11	SKUT1	N	4	0	2	N
MSH2	FIPNDVTLK	ENDOMETRIUM	650	p.Y656fs	c.1966_1966delT	Frame_Shift_Del	3	0.11	HEC108	N	5	0	9	N
MSH2	GSQSGCLAE	ENDOMETRIUM	322	p.S325fs	c.973_974delTC	Frame_Shift_Del	5	0.11	JHUEM1	N	0	0	0	N
MSH2	HELSLGQSD	SOFT_TISSUE	785	p.T788fs	c.2363_2364delCT	Frame_Shift_Del	5	0.11	SKUT1	N	0	0	0	N
MSH2	HFHELSLGQ	SOFT_TISSUE	783	p.T788fs	c.2363_2364delCT	Frame_Shift_Del	4	0.11	SKUT1	N	0	0	0	N
MSH2	IAFIPNDVT	ENDOMETRIUM	648	p.Y656fs	c.1966_1966delT	Frame_Shift_Del	1	0.11	HEC108	N	5	0	0	N
MSH2	INRCSTSLL	ENDOMETRIUM	660	p.Y656fs	c.1966_1966delT	Frame_Shift_Del	5	0.11	HEC108	N	7	0	8	N
MSH2	IPNDVTLKK	ENDOMETRIUM	651	p.Y656fs	c.1966_1966delT	Frame_Shift_Del	3	0.11	HEC108	Y	4	12	10	N
MSH2	IWEVNQHIF	ENDOMETRIUM	671	p.Y656fs	c.1966_1966delT	Frame_Shift_Del	5	0.11	HEC108	N	4	0	0	N
MSH2	KASPGNLSV	OVARY	122	p.N127fs	c.381_382delTC	Frame_Shift_Del	1	0.11	EFO27	N	6	0	0	N
MSH2	KINRCSTSL	ENDOMETRIUM	659	p.Y656fs	c.1966_1966delT	Frame_Shift_Del	5	0.11	HEC108	Y	10	10	0	N
MSH2	KKINRCSTS	ENDOMETRIUM	658	p.Y656fs	c.1966_1966delT	Frame_Shift_Del	5	0.11	HEC108	N	2	0	0	N
MSH2	LAPIWEVNQ	ENDOMETRIUM	668	p.Y656fs	c.1966_1966delT	Frame_Shift_Del	6	0.11	HEC108	N	0	0	0	N
MSH2	LKKINRCST	ENDOMETRIUM	657	p.Y656fs	c.1966_1966delT	Frame_Shift_Del	5	0.11	HEC108	N	1	0	1	N
MSH2	LLAPIWEVN	ENDOMETRIUM	667	p.Y656fs	c.1966_1966delT	Frame_Shift_Del	5	0.11	HEC108	N	0	0	0	N
MSH2	LSLGQSDTN	SOFT_TISSUE	787	p.T788fs	c.2363_2364delCT	Frame_Shift_Del	5	0.11	SKUT1	N	0	0	0	N
MSH2	NDVTLKKIN	ENDOMETRIUM	653	p.Y656fs	c.1966_1966delT	Frame_Shift_Del	5	0.11	HEC108	N	2	0	0	N
MSH2	NQHIFDKLG	ENDOMETRIUM	675	p.Y656fs	c.1966_1966delT	Frame_Shift_Del	5	0.11	HEC108	N	0	0	0	N
MSH2	NRCSTSLLA	ENDOMETRIUM	661	p.Y656fs	c.1966_1966delT	Frame_Shift_Del	5	0.11	HEC108	N	2	0	0	N
MSH2	PIWEVNQHI	ENDOMETRIUM	670	p.Y656fs	c.1966_1966delT	Frame_Shift_Del	5	0.11	HEC108	N	2	0	0	N
MSH2	PNDVTLKKI	ENDOMETRIUM	652	p.Y656fs	c.1966_1966delT	Frame_Shift_Del	4	0.11	HEC108	N	0	0	0	N
MSH2	RCSTSLLAP	ENDOMETRIUM	662	p.Y656fs	c.1966_1966delT	Frame_Shift_Del	5	0.11	HEC108	N	0	0	0	N
MSH2	SLGQSDTNC	SOFT_TISSUE	788	p.T788fs	c.2363_2364delCT	Frame_Shift_Del	6	0.11	SKUT1	N	2	0	0	N
MSH2	SLLAPIWEV	ENDOMETRIUM	666	p.Y656fs	c.1966_1966delT	Frame_Shift_Del	5	0.11	HEC108	Y	8	9	0	N
MSH2	STSLLAPIW	ENDOMETRIUM	664	p.Y656fs	c.1966_1966delT	Frame_Shift_Del	5	0.11	HEC108	N	1	0	0	N
MSH2	TGSQSGCLA	ENDOMETRIUM	321	p.S325fs	c.973_974delTC	Frame_Shift_Del	4	0.11	JHUEM1	N	1	0	0	N
MSH2	THFHELSLG	SOFT_TISSUE	782	p.T788fs	c.2363_2364delCT	Frame_Shift_Del	3	0.11	SKUT1	N	0	0	0	N
MSH2	TLKKINRCS	ENDOMETRIUM	656	p.Y656fs	c.1966_1966delT	Frame_Shift_Del	5	0.11	HEC108	N	1	0	0	N
MSH2	TSLLAPIWE	ENDOMETRIUM	665	p.Y656fs	c.1966_1966delT	Frame_Shift_Del	5	0.11	HEC108	N	0	0	0	N
MSH2	TTGSQSGCL	ENDOMETRIUM	320	p.S325fs	c.973_974delTC	Frame_Shift_Del	3	0.11	JHUEM1	N	4	0	0	N
MSH2	VNQHIFDKL	ENDOMETRIUM	674	p.Y656fs	c.1966_1966delT	Frame_Shift_Del	4	0.11	HEC108	N	11	0	0	N
MSH2	VTLKKINRC	ENDOMETRIUM	655	p.Y656fs	c.1966_1966delT	Frame_Shift_Del	5	0.11	HEC108	N	1	0	13	N
MSH2	WEVNQHIFD	ENDOMETRIUM	672	p.Y656fs	c.1966_1966delT	Frame_Shift_Del	5	0.11	HEC108	N	3	0	1	N
MSH2	DPNLSELSK	ENDOMETRIUM	475	p.L481fs	c.1441_1442insTAAG	Frame_Shift_Ins	2	0.11	HEC59	N	1	0	0	Y
MSH2	FDPNLSELS	ENDOMETRIUM	474	p.L481fs	c.1441_1442insTAAG	Frame_Shift_Ins	1	0.11	HEC59	N	5	0	2	N
MSH2	LSELSKRNN	ENDOMETRIUM	478	p.L481fs	c.1441_1442insTAAG	Frame_Shift_Ins	4	0.11	HEC59	N	1	0	0	N
MSH2	NLSELSKRN	ENDOMETRIUM	477	p.L481fs	c.1441_1442insTAAG	Frame_Shift_Ins	4	0.11	HEC59	N	0	0	0	N
MSH2	PNLSELSKR	ENDOMETRIUM	476	p.L481fs	c.1441_1442insTAAG	Frame_Shift_Ins	3	0.11	HEC59	N	0	0	0	Y
MSH2	SELSKRNNE	ENDOMETRIUM	479	p.L481fs	c.1441_1442insTAAG	Frame_Shift_Ins	4	0.11	HEC59	N	1	0	0	N
MSH2	ALIQIGPKE	OVARY	189	p.L191del	c.568_570delCTC	In_Frame_Del	1	0.11	OC316	N	0	0	0	N
MSH2	AQLDAVSFA	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	600	p.V606del	c.1816_1818delGTC	In_Frame_Del	3	0.11	HT	N	6	0	0	N
MSH2	AVSFAHVSN	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	604	p.V606del	c.1816_1818delGTC	In_Frame_Del	1	0.11	HT	N	0	0	0	N
MSH2	DAVSFAHVS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	603	p.V606del	c.1816_1818delGTC	In_Frame_Del	2	0.11	HT	N	1	0	0	N
MSH2	DLLVRQYRV	LUNG	91	p.L94del	c.273_275delTCT	In_Frame_Del	1	0.11	NCIH1734	Y	8	9	0	N
MSH2	EALIQIGPK	OVARY	188	p.L191del	c.568_570delCTC	In_Frame_Del	2	0.11	OC316	N	1	0	0	N
MSH2	ESFVKDLLV	LUNG	86	p.L94del	c.273_275delTCT	In_Frame_Del	1	0.11	NCIH1734	N	9	0	0	N
MSH2	FSNLEALIQ	OVARY	184	p.L191del	c.568_570delCTC	In_Frame_Del	2	0.11	OC316	N	2	0	17	N
MSH2	FVKDLLVRQ	LUNG	88	p.L94del	c.273_275delTCT	In_Frame_Del	3	0.11	NCIH1734	N	2	0	12	N
MSH2	KDLLVRQYR	LUNG	90	p.L94del	c.273_275delTCT	In_Frame_Del	2	0.11	NCIH1734	N	0	0	0	N
MSH2	LAQLDAVSF	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	599	p.V606del	c.1816_1818delGTC	In_Frame_Del	2	0.11	HT	N	7	0	2	N
MSH2	LDAVSFAHV	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	602	p.V606del	c.1816_1818delGTC	In_Frame_Del	3	0.11	HT	N	4	0	0	N
MSH2	LEALIQIGP	OVARY	187	p.L191del	c.568_570delCTC	In_Frame_Del	3	0.11	OC316	N	0	0	0	N
MSH2	NLEALIQIG	OVARY	186	p.L191del	c.568_570delCTC	In_Frame_Del	4	0.11	OC316	N	1	0	0	N
MSH2	QFSNLEALI	OVARY	183	p.L191del	c.568_570delCTC	In_Frame_Del	1	0.11	OC316	N	4	0	0	N
MSH2	QLDAVSFAH	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	601	p.V606del	c.1816_1818delGTC	In_Frame_Del	4	0.11	HT	N	2	0	0	N
MSH2	SFVKDLLVR	LUNG	87	p.L94del	c.273_275delTCT	In_Frame_Del	2	0.11	NCIH1734	N	2	0	0	N
MSH2	SNLEALIQI	OVARY	185	p.L191del	c.568_570delCTC	In_Frame_Del	3	0.11	OC316	Y	7	10	0	N
MSH2	VKDLLVRQY	LUNG	89	p.L94del	c.273_275delTCT	In_Frame_Del	3	0.11	NCIH1734	N	5	0	4	N
MSH2	VLAQLDAVS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	598	p.V606del	c.1816_1818delGTC	In_Frame_Del	1	0.11	HT	N	0	0	0	N
MSH2	AAEVGLVRF	LUNG	14	p.F19L	c.57C>A	Missense_Mutation	1	0.11	NCIH596	N	4	0	0	N
MSH2	AAVKALNLF	LARGE_INTESTINE	305	p.R308K	c.923G>A	Missense_Mutation	1	0.11	KM12	N	6	0	0	N
MSH2	AELANFTKH	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	831	p.P837T	c.2509C>A	Missense_Mutation	1	0.11	MOLM13	N	3	0	0	N
MSH2	AEVGLVRFF	LUNG	15	p.F19L	c.57C>A	Missense_Mutation	1	0.11	NCIH596	Y	7	10	0	N
MSH2	AGANNLQSV	ENDOMETRIUM	70	p.K73N	c.219G>T	Missense_Mutation	1	0.11	HEC251	N	7	0	0	N
MSH2	AKKFQRQTA	ENDOMETRIUM	391	p.A398T	c.1192G>A	Missense_Mutation	1	0.11	HEC108	N	2	0	0	Y
MSH2	ALNLFQVSV	LIVER	309	p.G315V	c.944G>T	Missense_Mutation	1	0.11	SKHEP1	Y	6	10	0	N
MSH2	ANFTKHVIE	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	834	p.P837T	c.2509C>A	Missense_Mutation	1	0.11	MOLM13	N	0	0	0	N
MSH2	ANNLQSVVL	ENDOMETRIUM	72	p.K73N	c.219G>T	Missense_Mutation	1	0.11	HEC251	Y	4	15	0	N
MSH2	AQIGCSVPC	PANCREAS	689	p.F694S	c.2081T>C	Missense_Mutation	1	0.11	SNU324	N	2	0	0	N
MSH2	AQLDAVASF	LARGE_INTESTINE	600	p.V606A	c.1817T>C	Missense_Mutation	1	0.11	SNU175	Y	10	9	0	N
MSH2	ASFAHVSNG	LARGE_INTESTINE	606	p.V606A	c.1817T>C	Missense_Mutation	1	0.11	SNU175	Y	0	12	0	N
MSH2	ASIIRSATK	PROSTATE	733	p.L736I	c.2206C>A	Missense_Mutation	1	0.11	DU145	Y	2	11	0	N
MSH2	AVASFAHVS	LARGE_INTESTINE	604	p.V606A	c.1817T>C	Missense_Mutation	1	0.11	SNU175	N	0	0	0	N
MSH2	AVKALNLFQ	LARGE_INTESTINE	306	p.R308K	c.923G>A	Missense_Mutation	1	0.11	KM12	N	0	0	0	N
MSH2	AVQQKETLQ	STOMACH	2	p.P5Q	c.14C>A	Missense_Mutation	1	0.11	SNU601	N	0	0	0	N
MSH2	CMGPAGAKN	ENDOMETRIUM	66	p.Y66C	c.197A>G	Missense_Mutation	1	0.11	HEC251	N	0	0	0	N
MSH2	CSVPCESAE	PANCREAS	693	p.F694S	c.2081T>C	Missense_Mutation	1	0.11	SNU324	N	0	0	0	N
MSH2	DAVASFAHV	LARGE_INTESTINE	603	p.V606A	c.1817T>C	Missense_Mutation	1	0.11	SNU175	Y	5	10	0	N
MSH2	DIAAVKALN	LARGE_INTESTINE	303	p.R308K	c.923G>A	Missense_Mutation	1	0.11	KM12	N	0	0	0	N
MSH2	DLEKKIQST	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	487	p.M492I	c.1476G>A	Missense_Mutation	1	0.11	SR786	N	0	0	0	N
MSH2	DMDQVENHK	BREAST	459	p.E467K	c.1399G>A	Missense_Mutation	1	0.11	HCC2218	N	5	0	0	N
MSH2	DQVENHKFL	BREAST	461	p.E467K	c.1399G>A	Missense_Mutation	1	0.11	HCC2218	N	15	0	0	N
MSH2	DSIQRKLGP	LARGE_INTESTINE	167	p.L175P	c.524T>C	Missense_Mutation	1	0.11	CCK81	N	0	0	0	N
MSH2	DSQLKGVFT	SKIN	716	p.S723F	c.2168C>T	Missense_Mutation	1	0.11	SKMEL2	N	1	0	0	N
MSH2	DVLVQLDAV	LARGE_INTESTINE	597	p.A600V	c.1799C>T	Missense_Mutation	1	0.11	HRT18	Y	4	10	0	N
MSH2	EEFQYIGEL	LIVER	852	p.S860L	c.2579C>T	Missense_Mutation	1	0.11	ALEXANDERCELLS	Y	11	11	0	N
MSH2	EFQYIGELQ	LIVER	853	p.S860L	c.2579C>T	Missense_Mutation	1	0.11	ALEXANDERCELLS	N	0	0	0	N
MSH2	EKKIQSTLI	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	489	p.M492I	c.1476G>A	Missense_Mutation	1	0.11	SR786	N	2	0	0	N
MSH2	ELANFTKHV	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	832	p.P837T	c.2509C>A	Missense_Mutation	1	0.11	MOLM13	N	4	0	0	N
MSH2	ELQGYDIME	LIVER	859	p.S860L	c.2579C>T	Missense_Mutation	1	0.11	ALEXANDERCELLS	N	0	0	0	N
MSH2	EMLETASII	PROSTATE	728	p.L736I	c.2206C>A	Missense_Mutation	1	0.11	DU145	N	12	0	0	N
MSH2	ENHKFLVKP	BREAST	464	p.E467K	c.1399G>A	Missense_Mutation	1	0.11	HCC2218	N	0	0	0	N
MSH2	ESAAEVGLV	LUNG	12	p.F19L	c.57C>A	Missense_Mutation	1	0.11	NCIH596	N	3	0	0	N
MSH2	ETASIIRSA	PROSTATE	731	p.L736I	c.2206C>A	Missense_Mutation	1	0.11	DU145	N	3	0	0	N
MSH2	EVGLVRFFQ	LUNG	16	p.F19L	c.57C>A	Missense_Mutation	1	0.11	NCIH596	N	1	0	0	N
MSH2	FKTQGVIKC	ENDOMETRIUM	58	p.Y66C	c.197A>G	Missense_Mutation	1	0.11	HEC251	N	3	0	18	N
MSH2	FQRQTANLQ	ENDOMETRIUM	394	p.A398T	c.1192G>A	Missense_Mutation	1	0.11	HEC108	N	2	0	22	Y
MSH2	FQVSVEDTT	LIVER	313	p.G315V	c.944G>T	Missense_Mutation	1	0.11	SKHEP1	N	4	0	0	N
MSH2	FQYIGELQG	LIVER	854	p.S860L	c.2579C>T	Missense_Mutation	1	0.11	ALEXANDERCELLS	N	2	0	6	N
MSH2	FTFMAEMLE	SKIN	723	p.S723F	c.2168C>T	Missense_Mutation	1	0.11	SKMEL2	N	2	0	4	N
MSH2	FTKHVIECA	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	836	p.P837T	c.2509C>A	Missense_Mutation	1	0.11	MOLM13	N	5	0	0	N
MSH2	GANNLQSVV	ENDOMETRIUM	71	p.K73N	c.219G>T	Missense_Mutation	1	0.11	HEC251	N	6	0	0	N
MSH2	GCSVPCESA	PANCREAS	692	p.F694S	c.2081T>C	Missense_Mutation	1	0.11	SNU324	N	1	0	0	N
MSH2	GDSQLKGVF	SKIN	715	p.S723F	c.2168C>T	Missense_Mutation	1	0.11	SKMEL2	N	6	0	0	N
MSH2	GELQGYDIM	LIVER	858	p.S860L	c.2579C>T	Missense_Mutation	1	0.11	ALEXANDERCELLS	N	10	0	0	N
MSH2	GKHQKLLLV	CENTRAL_NERVOUS_SYSTEM	426	p.A434V	c.1301C>T	Missense_Mutation	1	0.11	SW1783	N	4	0	0	N
MSH2	GLVRFFQGM	LUNG	18	p.F19L	c.57C>A	Missense_Mutation	1	0.11	NCIH596	N	11	0	0	N
MSH2	GPAGANNLQ	ENDOMETRIUM	68	p.K73N	c.219G>T	Missense_Mutation	1	0.11	HEC251	N	0	0	0	N
MSH2	GPCEFPDND	LARGE_INTESTINE	174	p.L175P	c.524T>C	Missense_Mutation	1	0.11	CCK81	N	0	0	0	N
MSH2	GVFTFMAEM	SKIN	721	p.S723F	c.2168C>T	Missense_Mutation	1	0.11	SKMEL2	Y	10	10	0	N
MSH2	GVIKCMGPA	ENDOMETRIUM	62	p.Y66C	c.197A>G	Missense_Mutation	1	0.11	HEC251	N	2	0	0	N
MSH2	HKFLVKPSF	BREAST	466	p.E467K	c.1399G>A	Missense_Mutation	1	0.11	HCC2218	N	4	0	0	N
MSH2	HKNRIEERL	LUNG	352	p.D352H	c.1054G>C	Missense_Mutation	1	0.11	NCIH522	N	4	0	0	N
MSH2	HQKLLLVVF	CENTRAL_NERVOUS_SYSTEM	428	p.A434V	c.1301C>T	Missense_Mutation	1	0.11	SW1783	N	7	0	0	N
MSH2	HVAELANFT	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	829	p.P837T	c.2509C>A	Missense_Mutation	1	0.11	MOLM13	N	2	0	0	N
MSH2	IAAVKALNL	LARGE_INTESTINE	304	p.R308K	c.923G>A	Missense_Mutation	1	0.11	KM12	Y	13	9	3	N
MSH2	IGCSVPCES	PANCREAS	691	p.F694S	c.2081T>C	Missense_Mutation	1	0.11	SNU324	N	0	0	5	N
MSH2	IGELQGYDI	LIVER	857	p.S860L	c.2579C>T	Missense_Mutation	1	0.11	ALEXANDERCELLS	N	7	0	1	N
MSH2	IIRSATKDS	PROSTATE	735	p.L736I	c.2206C>A	Missense_Mutation	1	0.11	DU145	N	0	0	31	N
MSH2	IKCMGPAGA	ENDOMETRIUM	64	p.Y66C	c.197A>G	Missense_Mutation	1	0.11	HEC251	N	2	0	21	N
MSH2	IKQPLMHKN	LUNG	346	p.D352H	c.1054G>C	Missense_Mutation	1	0.11	NCIH522	N	1	0	0	N
MSH2	IMNDLEKKI	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	484	p.M492I	c.1476G>A	Missense_Mutation	1	0.11	SR786	N	8	0	0	N
MSH2	IQRKLGPCE	LARGE_INTESTINE	169	p.L175P	c.524T>C	Missense_Mutation	1	0.11	CCK81	N	1	0	4	N
MSH2	IQSTLISAA	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	492	p.M492I	c.1476G>A	Missense_Mutation	1	0.11	SR786	N	4	0	0	N
MSH2	IRSATKDSL	PROSTATE	736	p.L736I	c.2206C>A	Missense_Mutation	1	0.11	DU145	N	6	0	6	N
MSH2	KALNLFQGS	LARGE_INTESTINE	308	p.R308K	c.923G>A	Missense_Mutation	1	0.11	KM12	N	3	0	0	N
MSH2	KCMGPAGAK	ENDOMETRIUM	65	p.Y66C	c.197A>G	Missense_Mutation	1	0.11	HEC251	N	4	0	0	N
MSH2	KFLVKPSFD	BREAST	467	p.E467K	c.1399G>A	Missense_Mutation	1	0.11	HCC2218	N	0	0	0	N
MSH2	KFQRQTANL	ENDOMETRIUM	393	p.A398T	c.1192G>A	Missense_Mutation	1	0.11	HEC108	Y	9	11	0	N
MSH2	KGVFTFMAE	SKIN	720	p.S723F	c.2168C>T	Missense_Mutation	1	0.11	SKMEL2	N	0	0	0	N
MSH2	KHQKLLLVV	CENTRAL_NERVOUS_SYSTEM	427	p.A434V	c.1301C>T	Missense_Mutation	1	0.11	SW1783	N	4	0	0	N
MSH2	KIQSTLISA	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	491	p.M492I	c.1476G>A	Missense_Mutation	1	0.11	SR786	Y	5	9	0	N
MSH2	KKFQRQTAN	ENDOMETRIUM	392	p.A398T	c.1192G>A	Missense_Mutation	1	0.11	HEC108	N	1	0	0	Y
MSH2	KKIQSTLIS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	490	p.M492I	c.1476G>A	Missense_Mutation	1	0.11	SR786	N	1	0	0	N
MSH2	KLDIAAVKA	LARGE_INTESTINE	301	p.R308K	c.923G>A	Missense_Mutation	1	0.11	KM12	N	3	0	0	N
MSH2	KLGPCEFPD	LARGE_INTESTINE	172	p.L175P	c.524T>C	Missense_Mutation	1	0.11	CCK81	N	0	0	0	Y
MSH2	KLLLVVFVT	CENTRAL_NERVOUS_SYSTEM	430	p.A434V	c.1301C>T	Missense_Mutation	1	0.11	SW1783	N	5	0	0	N
MSH2	KQPLMHKNR	LUNG	347	p.D352H	c.1054G>C	Missense_Mutation	1	0.11	NCIH522	N	5	0	0	N
MSH2	KTQGVIKCM	ENDOMETRIUM	59	p.Y66C	c.197A>G	Missense_Mutation	1	0.11	HEC251	Y	4	9	0	N
MSH2	KYMGPAGAN	ENDOMETRIUM	65	p.K73N	c.219G>T	Missense_Mutation	1	0.11	HEC251	N	2	0	0	N
MSH2	LAKKFQRQT	ENDOMETRIUM	390	p.A398T	c.1192G>A	Missense_Mutation	1	0.11	HEC108	N	4	0	0	N
MSH2	LANFTKHVI	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	833	p.P837T	c.2509C>A	Missense_Mutation	1	0.11	MOLM13	N	7	0	13	N
MSH2	LAQLDAVAS	LARGE_INTESTINE	599	p.V606A	c.1817T>C	Missense_Mutation	1	0.11	SNU175	N	1	0	2	N
MSH2	LDAVASFAH	LARGE_INTESTINE	602	p.V606A	c.1817T>C	Missense_Mutation	1	0.11	SNU175	N	0	0	0	N
MSH2	LDIAAVKAL	LARGE_INTESTINE	302	p.R308K	c.923G>A	Missense_Mutation	1	0.11	KM12	N	7	0	0	N
MSH2	LEKKIQSTL	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	488	p.M492I	c.1476G>A	Missense_Mutation	1	0.11	SR786	N	10	0	0	N
MSH2	LESAAEVGL	LUNG	11	p.F19L	c.57C>A	Missense_Mutation	1	0.11	NCIH596	N	8	0	0	N
MSH2	LETASIIRS	PROSTATE	730	p.L736I	c.2206C>A	Missense_Mutation	1	0.11	DU145	N	4	0	4	N
MSH2	LFQVSVEDT	LIVER	312	p.G315V	c.944G>T	Missense_Mutation	1	0.11	SKHEP1	N	1	0	0	N
MSH2	LGPCEFPDN	LARGE_INTESTINE	173	p.L175P	c.524T>C	Missense_Mutation	1	0.11	CCK81	N	1	0	0	N
MSH2	LKGVFTFMA	SKIN	719	p.S723F	c.2168C>T	Missense_Mutation	1	0.11	SKMEL2	N	4	0	15	N
MSH2	LLLVVFVTP	CENTRAL_NERVOUS_SYSTEM	431	p.A434V	c.1301C>T	Missense_Mutation	1	0.11	SW1783	N	0	0	0	N
MSH2	LLVVFVTPL	CENTRAL_NERVOUS_SYSTEM	432	p.A434V	c.1301C>T	Missense_Mutation	1	0.11	SW1783	N	20	0	8	N
MSH2	LMAQIGCSV	PANCREAS	687	p.F694S	c.2081T>C	Missense_Mutation	1	0.11	SNU324	N	6	0	2	N
MSH2	LMHKNRIEE	LUNG	350	p.D352H	c.1054G>C	Missense_Mutation	1	0.11	NCIH522	N	1	0	8	N
MSH2	LNDVLVQLD	LARGE_INTESTINE	595	p.A600V	c.1799C>T	Missense_Mutation	1	0.11	HRT18	N	0	0	0	N
MSH2	LNLFQVSVE	LIVER	310	p.G315V	c.944G>T	Missense_Mutation	1	0.11	SKHEP1	N	0	0	12	N
MSH2	LQGYDIMEP	LIVER	860	p.S860L	c.2579C>T	Missense_Mutation	1	0.11	ALEXANDERCELLS	N	0	0	9	N
MSH2	LVQLDAVVS	LARGE_INTESTINE	599	p.A600V	c.1799C>T	Missense_Mutation	1	0.11	HRT18	N	0	0	42	N
MSH2	LVRFFQGMP	LUNG	19	p.F19L	c.57C>A	Missense_Mutation	1	0.11	NCIH596	N	0	0	2	N
MSH2	LVVFVTPLT	CENTRAL_NERVOUS_SYSTEM	433	p.A434V	c.1301C>T	Missense_Mutation	1	0.11	SW1783	N	2	0	30	N
MSH2	MAQIGCSVP	PANCREAS	688	p.F694S	c.2081T>C	Missense_Mutation	1	0.11	SNU324	N	0	0	0	N
MSH2	MAVQQKETL	STOMACH	1	p.P5Q	c.14C>A	Missense_Mutation	1	0.11	SNU601	Y	16	10	0	N
MSH2	MDQVENHKF	BREAST	460	p.E467K	c.1399G>A	Missense_Mutation	1	0.11	HCC2218	N	4	0	0	N
MSH2	MGPAGANNL	ENDOMETRIUM	67	p.K73N	c.219G>T	Missense_Mutation	1	0.11	HEC251	N	12	0	4	Y
MSH2	MHKNRIEER	LUNG	351	p.D352H	c.1054G>C	Missense_Mutation	1	0.11	NCIH522	N	1	0	0	N
MSH2	MKLDIAAVK	LARGE_INTESTINE	300	p.R308K	c.923G>A	Missense_Mutation	1	0.11	KM12	N	1	0	11	N
MSH2	MLETASIIR	PROSTATE	729	p.L736I	c.2206C>A	Missense_Mutation	1	0.11	DU145	N	7	0	2	N
MSH2	MNDLEKKIQ	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	485	p.M492I	c.1476G>A	Missense_Mutation	1	0.11	SR786	N	0	0	5	N
MSH2	MQTLNDVLV	LARGE_INTESTINE	592	p.A600V	c.1799C>T	Missense_Mutation	1	0.11	HRT18	N	12	0	0	N
MSH2	NDLEKKIQS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	486	p.M492I	c.1476G>A	Missense_Mutation	1	0.11	SR786	N	2	0	0	N
MSH2	NDVLVQLDA	LARGE_INTESTINE	596	p.A600V	c.1799C>T	Missense_Mutation	1	0.11	HRT18	N	4	0	0	N
MSH2	NFTKHVIEC	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	835	p.P837T	c.2509C>A	Missense_Mutation	1	0.11	MOLM13	N	1	0	0	N
MSH2	NHKFLVKPS	BREAST	465	p.E467K	c.1399G>A	Missense_Mutation	1	0.11	HCC2218	N	0	0	0	N
MSH2	NLFQVSVED	LIVER	311	p.G315V	c.944G>T	Missense_Mutation	1	0.11	SKHEP1	N	0	0	0	N
MSH2	NNLQSVVLS	ENDOMETRIUM	73	p.K73N	c.219G>T	Missense_Mutation	1	0.11	HEC251	N	0	0	0	N
MSH2	PAGANNLQS	ENDOMETRIUM	69	p.K73N	c.219G>T	Missense_Mutation	1	0.11	HEC251	N	0	0	0	N
MSH2	PCEFPDNDQ	LARGE_INTESTINE	175	p.L175P	c.524T>C	Missense_Mutation	1	0.11	CCK81	N	0	0	0	N
MSH2	PLMHKNRIE	LUNG	349	p.D352H	c.1054G>C	Missense_Mutation	1	0.11	NCIH522	N	0	0	0	N
MSH2	QGVIKCMGP	ENDOMETRIUM	61	p.Y66C	c.197A>G	Missense_Mutation	1	0.11	HEC251	N	0	0	0	N
MSH2	QIGCSVPCE	PANCREAS	690	p.F694S	c.2081T>C	Missense_Mutation	1	0.11	SNU324	N	0	0	0	N
MSH2	QKETLQLES	STOMACH	5	p.P5Q	c.14C>A	Missense_Mutation	1	0.11	SNU601	N	1	0	0	N
MSH2	QKLLLVVFV	CENTRAL_NERVOUS_SYSTEM	429	p.A434V	c.1301C>T	Missense_Mutation	1	0.11	SW1783	N	6	0	0	N
MSH2	QLDAVASFA	LARGE_INTESTINE	601	p.V606A	c.1817T>C	Missense_Mutation	1	0.11	SNU175	N	2	0	0	N
MSH2	QLKGVFTFM	SKIN	718	p.S723F	c.2168C>T	Missense_Mutation	1	0.11	SKMEL2	N	6	0	0	N
MSH2	QPLMHKNRI	LUNG	348	p.D352H	c.1054G>C	Missense_Mutation	1	0.11	NCIH522	N	14	0	0	N
MSH2	QQKETLQLE	STOMACH	4	p.P5Q	c.14C>A	Missense_Mutation	1	0.11	SNU601	N	0	0	0	N
MSH2	QRKLGPCEF	LARGE_INTESTINE	170	p.L175P	c.524T>C	Missense_Mutation	1	0.11	CCK81	Y	2	9	0	N
MSH2	QRQTANLQD	ENDOMETRIUM	395	p.A398T	c.1192G>A	Missense_Mutation	1	0.11	HEC108	N	1	0	0	N
MSH2	QTANLQDCY	ENDOMETRIUM	397	p.A398T	c.1192G>A	Missense_Mutation	1	0.11	HEC108	N	6	0	0	N
MSH2	QTLNDVLVQ	LARGE_INTESTINE	593	p.A600V	c.1799C>T	Missense_Mutation	1	0.11	HRT18	N	0	0	0	N
MSH2	QVENHKFLV	BREAST	462	p.E467K	c.1399G>A	Missense_Mutation	1	0.11	HCC2218	N	2	0	0	N
MSH2	QVSVEDTTG	LIVER	314	p.G315V	c.944G>T	Missense_Mutation	1	0.11	SKHEP1	N	0	0	0	N
MSH2	QWIKQPLMH	LUNG	344	p.D352H	c.1054G>C	Missense_Mutation	1	0.11	NCIH522	N	0	0	0	N
MSH2	QYIGELQGY	LIVER	855	p.S860L	c.2579C>T	Missense_Mutation	1	0.11	ALEXANDERCELLS	N	5	0	0	N
MSH2	RALNLFQVS	LIVER	308	p.G315V	c.944G>T	Missense_Mutation	1	0.11	SKHEP1	N	3	0	0	N
MSH2	RKLGPCEFP	LARGE_INTESTINE	171	p.L175P	c.524T>C	Missense_Mutation	1	0.11	CCK81	N	0	0	0	Y
MSH2	RQTANLQDC	ENDOMETRIUM	396	p.A398T	c.1192G>A	Missense_Mutation	1	0.11	HEC108	N	5	0	0	N
MSH2	SAAEVGLVR	LUNG	13	p.F19L	c.57C>A	Missense_Mutation	1	0.11	NCIH596	N	4	0	0	N
MSH2	SIIRSATKD	PROSTATE	734	p.L736I	c.2206C>A	Missense_Mutation	1	0.11	DU145	N	0	0	0	N
MSH2	SIQRKLGPC	LARGE_INTESTINE	168	p.L175P	c.524T>C	Missense_Mutation	1	0.11	CCK81	N	0	0	0	N
MSH2	SQLKGVFTF	SKIN	717	p.S723F	c.2168C>T	Missense_Mutation	1	0.11	SKMEL2	Y	10	9	0	N
MSH2	SVPCESAEV	PANCREAS	694	p.F694S	c.2081T>C	Missense_Mutation	1	0.11	SNU324	Y	3	11	0	N
MSH2	TANLQDCYR	ENDOMETRIUM	398	p.A398T	c.1192G>A	Missense_Mutation	1	0.11	HEC108	N	3	0	0	N
MSH2	TASIIRSAT	PROSTATE	732	p.L736I	c.2206C>A	Missense_Mutation	1	0.11	DU145	N	3	0	0	N
MSH2	TKHVIECAK	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	837	p.P837T	c.2509C>A	Missense_Mutation	1	0.11	MOLM13	N	1	0	0	N
MSH2	TLNDVLVQL	LARGE_INTESTINE	594	p.A600V	c.1799C>T	Missense_Mutation	1	0.11	HRT18	Y	17	12	0	N
MSH2	TQGVIKCMG	ENDOMETRIUM	60	p.Y66C	c.197A>G	Missense_Mutation	1	0.11	HEC251	N	0	0	0	N
MSH2	VAELANFTK	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	830	p.P837T	c.2509C>A	Missense_Mutation	1	0.11	MOLM13	N	3	0	0	N
MSH2	VASFAHVSN	LARGE_INTESTINE	605	p.V606A	c.1817T>C	Missense_Mutation	1	0.11	SNU175	N	1	0	0	N
MSH2	VENHKFLVK	BREAST	463	p.E467K	c.1399G>A	Missense_Mutation	1	0.11	HCC2218	Y	1	14	0	N
MSH2	VFTFMAEML	SKIN	722	p.S723F	c.2168C>T	Missense_Mutation	1	0.11	SKMEL2	N	9	0	3	N
MSH2	VGLVRFFQG	LUNG	17	p.F19L	c.57C>A	Missense_Mutation	1	0.11	NCIH596	N	0	0	0	N
MSH2	VIKCMGPAG	ENDOMETRIUM	63	p.Y66C	c.197A>G	Missense_Mutation	1	0.11	HEC251	N	0	0	0	N
MSH2	VKALNLFQG	LARGE_INTESTINE	307	p.R308K	c.923G>A	Missense_Mutation	1	0.11	KM12	N	0	0	4	N
MSH2	VLAQLDAVA	LARGE_INTESTINE	598	p.V606A	c.1817T>C	Missense_Mutation	1	0.11	SNU175	N	4	0	0	N
MSH2	VLMAQIGCS	PANCREAS	686	p.F694S	c.2081T>C	Missense_Mutation	1	0.11	SNU324	N	0	0	30	N
MSH2	VLVQLDAVV	LARGE_INTESTINE	598	p.A600V	c.1799C>T	Missense_Mutation	1	0.11	HRT18	Y	8	13	0	N
MSH2	VQLDAVVSF	LARGE_INTESTINE	600	p.A600V	c.1799C>T	Missense_Mutation	1	0.11	HRT18	Y	12	9	14	N
MSH2	VQQKETLQL	STOMACH	3	p.P5Q	c.14C>A	Missense_Mutation	1	0.11	SNU601	N	14	0	21	N
MSH2	VRALNLFQV	LIVER	307	p.G315V	c.944G>T	Missense_Mutation	1	0.11	SKHEP1	Y	7	9	25	N
MSH2	VSVEDTTGS	LIVER	315	p.G315V	c.944G>T	Missense_Mutation	1	0.11	SKHEP1	N	0	0	5	N
MSH2	VVFVTPLTD	CENTRAL_NERVOUS_SYSTEM	434	p.A434V	c.1301C>T	Missense_Mutation	1	0.11	SW1783	N	0	0	25	N
MSH2	WIKQPLMHK	LUNG	345	p.D352H	c.1054G>C	Missense_Mutation	1	0.11	NCIH522	Y	5	11	6	N
MSH2	YIGELQGYD	LIVER	856	p.S860L	c.2579C>T	Missense_Mutation	1	0.11	ALEXANDERCELLS	N	2	0	0	N
MSH2	YMGPAGANN	ENDOMETRIUM	66	p.K73N	c.219G>T	Missense_Mutation	1	0.11	HEC251	N	2	0	0	N
MSH2	AEMLETTSI	LUNG	727	p.A733T	c.2197G>A	Missense_Mutation	1	0.22	RERFLCMS	N	6	0	0	N
MSH2	AEMLETTSI	LIVER	727	p.A733T	c.2197G>A	Missense_Mutation	1	0.22	SNU886	N	6	0	0	N
MSH2	AQFGYYFPV	OVARY	517	p.R524P	c.1571G>C	Missense_Mutation	1	0.22	OC316	Y	13	11	0	Y
MSH2	AQFGYYFPV	ENDOMETRIUM	517	p.R524P	c.1571G>C	Missense_Mutation	1	0.22	RL952	Y	13	11	0	Y
MSH2	EMLETTSIL	LUNG	728	p.A733T	c.2197G>A	Missense_Mutation	1	0.22	RERFLCMS	N	19	0	0	N
MSH2	EMLETTSIL	LIVER	728	p.A733T	c.2197G>A	Missense_Mutation	1	0.22	SNU886	N	19	0	0	N
MSH2	ESFVKYLLL	ENDOMETRIUM	86	p.D91Y	c.271G>T	Missense_Mutation	1	0.22	HEC251	Y	16	10	0	N
MSH2	ESFVKYLLL	ENDOMETRIUM	86	p.D91Y	c.271G>T	Missense_Mutation	1	0.22	JHUEM7	Y	16	10	0	N
MSH2	ETTSILRSA	LUNG	731	p.A733T	c.2197G>A	Missense_Mutation	1	0.22	RERFLCMS	N	1	0	0	N
MSH2	ETTSILRSA	LIVER	731	p.A733T	c.2197G>A	Missense_Mutation	1	0.22	SNU886	N	1	0	0	N
MSH2	FESFVKYLL	ENDOMETRIUM	85	p.D91Y	c.271G>T	Missense_Mutation	1	0.22	HEC251	Y	12	9	5	N
MSH2	FESFVKYLL	ENDOMETRIUM	85	p.D91Y	c.271G>T	Missense_Mutation	1	0.22	JHUEM7	Y	12	9	5	N
MSH2	FGYYFPVTC	OVARY	519	p.R524P	c.1571G>C	Missense_Mutation	1	0.22	OC316	N	7	0	12	N
MSH2	FGYYFPVTC	ENDOMETRIUM	519	p.R524P	c.1571G>C	Missense_Mutation	1	0.22	RL952	N	7	0	12	N
MSH2	FMAEMLETT	LUNG	725	p.A733T	c.2197G>A	Missense_Mutation	1	0.22	RERFLCMS	N	4	0	0	N
MSH2	FMAEMLETT	LIVER	725	p.A733T	c.2197G>A	Missense_Mutation	1	0.22	SNU886	N	4	0	0	N
MSH2	FPVTCKEEK	OVARY	523	p.R524P	c.1571G>C	Missense_Mutation	1	0.22	OC316	N	5	0	0	N
MSH2	FPVTCKEEK	ENDOMETRIUM	523	p.R524P	c.1571G>C	Missense_Mutation	1	0.22	RL952	N	5	0	0	N
MSH2	FVKYLLLVR	ENDOMETRIUM	88	p.D91Y	c.271G>T	Missense_Mutation	1	0.22	HEC251	N	8	0	20	N
MSH2	FVKYLLLVR	ENDOMETRIUM	88	p.D91Y	c.271G>T	Missense_Mutation	1	0.22	JHUEM7	N	8	0	20	N
MSH2	GYYFPVTCK	OVARY	520	p.R524P	c.1571G>C	Missense_Mutation	1	0.22	OC316	Y	3	11	0	N
MSH2	GYYFPVTCK	ENDOMETRIUM	520	p.R524P	c.1571G>C	Missense_Mutation	1	0.22	RL952	Y	3	11	0	N
MSH2	KYLLLVRQY	ENDOMETRIUM	90	p.D91Y	c.271G>T	Missense_Mutation	1	0.22	HEC251	Y	7	10	0	N
MSH2	KYLLLVRQY	ENDOMETRIUM	90	p.D91Y	c.271G>T	Missense_Mutation	1	0.22	JHUEM7	Y	7	10	0	N
MSH2	LETTSILRS	LUNG	730	p.A733T	c.2197G>A	Missense_Mutation	1	0.22	RERFLCMS	N	4	0	4	N
MSH2	LETTSILRS	LIVER	730	p.A733T	c.2197G>A	Missense_Mutation	1	0.22	SNU886	N	4	0	4	N
MSH2	MAEMLETTS	LUNG	726	p.A733T	c.2197G>A	Missense_Mutation	1	0.22	RERFLCMS	N	2	0	0	N
MSH2	MAEMLETTS	LIVER	726	p.A733T	c.2197G>A	Missense_Mutation	1	0.22	SNU886	N	2	0	0	N
MSH2	MLETTSILR	LUNG	729	p.A733T	c.2197G>A	Missense_Mutation	1	0.22	RERFLCMS	N	7	0	2	N
MSH2	MLETTSILR	LIVER	729	p.A733T	c.2197G>A	Missense_Mutation	1	0.22	SNU886	N	7	0	2	N
MSH2	MNFESFVKY	ENDOMETRIUM	83	p.D91Y	c.271G>T	Missense_Mutation	1	0.22	HEC251	N	8	0	0	N
MSH2	MNFESFVKY	ENDOMETRIUM	83	p.D91Y	c.271G>T	Missense_Mutation	1	0.22	JHUEM7	N	8	0	0	N
MSH2	NFESFVKYL	ENDOMETRIUM	84	p.D91Y	c.271G>T	Missense_Mutation	1	0.22	HEC251	N	8	0	0	N
MSH2	NFESFVKYL	ENDOMETRIUM	84	p.D91Y	c.271G>T	Missense_Mutation	1	0.22	JHUEM7	N	8	0	0	N
MSH2	PVTCKEEKV	OVARY	524	p.R524P	c.1571G>C	Missense_Mutation	1	0.22	OC316	N	1	0	0	N
MSH2	PVTCKEEKV	ENDOMETRIUM	524	p.R524P	c.1571G>C	Missense_Mutation	1	0.22	RL952	N	1	0	0	N
MSH2	QFGYYFPVT	OVARY	518	p.R524P	c.1571G>C	Missense_Mutation	1	0.22	OC316	N	1	0	0	N
MSH2	QFGYYFPVT	ENDOMETRIUM	518	p.R524P	c.1571G>C	Missense_Mutation	1	0.22	RL952	N	1	0	0	N
MSH2	SAQFGYYFP	OVARY	516	p.R524P	c.1571G>C	Missense_Mutation	1	0.22	OC316	N	0	0	0	N
MSH2	SAQFGYYFP	ENDOMETRIUM	516	p.R524P	c.1571G>C	Missense_Mutation	1	0.22	RL952	N	0	0	0	N
MSH2	SFVKYLLLV	ENDOMETRIUM	87	p.D91Y	c.271G>T	Missense_Mutation	1	0.22	HEC251	Y	4	10	0	N
MSH2	SFVKYLLLV	ENDOMETRIUM	87	p.D91Y	c.271G>T	Missense_Mutation	1	0.22	JHUEM7	Y	4	10	0	N
MSH2	TSILRSATK	LUNG	733	p.A733T	c.2197G>A	Missense_Mutation	1	0.22	RERFLCMS	N	2	0	0	N
MSH2	TSILRSATK	LIVER	733	p.A733T	c.2197G>A	Missense_Mutation	1	0.22	SNU886	N	2	0	0	N
MSH2	TTSILRSAT	LUNG	732	p.A733T	c.2197G>A	Missense_Mutation	1	0.22	RERFLCMS	N	1	0	0	N
MSH2	TTSILRSAT	LIVER	732	p.A733T	c.2197G>A	Missense_Mutation	1	0.22	SNU886	N	1	0	0	N
MSH2	VKYLLLVRQ	ENDOMETRIUM	89	p.D91Y	c.271G>T	Missense_Mutation	1	0.22	HEC251	N	0	0	28	N
MSH2	VKYLLLVRQ	ENDOMETRIUM	89	p.D91Y	c.271G>T	Missense_Mutation	1	0.22	JHUEM7	N	0	0	28	N
MSH2	YFPVTCKEE	OVARY	522	p.R524P	c.1571G>C	Missense_Mutation	1	0.22	OC316	N	2	0	4	N
MSH2	YFPVTCKEE	ENDOMETRIUM	522	p.R524P	c.1571G>C	Missense_Mutation	1	0.22	RL952	N	2	0	4	N
MSH2	YLLLVRQYR	ENDOMETRIUM	91	p.D91Y	c.271G>T	Missense_Mutation	1	0.22	HEC251	Y	7	9	15	N
MSH2	YLLLVRQYR	ENDOMETRIUM	91	p.D91Y	c.271G>T	Missense_Mutation	1	0.22	JHUEM7	Y	7	9	15	N
MSH2	YYFPVTCKE	OVARY	521	p.R524P	c.1571G>C	Missense_Mutation	1	0.22	OC316	N	2	0	4	N
MSH2	YYFPVTCKE	ENDOMETRIUM	521	p.R524P	c.1571G>C	Missense_Mutation	1	0.22	RL952	N	2	0	4	N
MSH2	IKALEKHEG	LIVER	418	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	JHH7	N	0	0	18	N
MSH2	IKALEKHEG	STOMACH	418	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	NCCSTCK140	N	0	0	18	N
MSH2	IKALEKHEG	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	418	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	SKM1	N	0	0	18	N
MSH2	IKALEKHEG	LARGE_INTESTINE	418	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	SNU283	N	0	0	18	N
MSH2	IKALEKHEG	CENTRAL_NERVOUS_SYSTEM	418	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	SNU738	N	0	0	18	N
MSH2	IKALEKHEG	OVARY	418	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	TYKNU	N	0	0	18	N
MSH2	INQLPNVIK	LIVER	411	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	JHH7	N	0	0	5	Y
MSH2	INQLPNVIK	STOMACH	411	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	NCCSTCK140	N	0	0	5	Y
MSH2	INQLPNVIK	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	411	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	SKM1	N	0	0	5	Y
MSH2	INQLPNVIK	LARGE_INTESTINE	411	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	SNU283	N	0	0	5	Y
MSH2	INQLPNVIK	CENTRAL_NERVOUS_SYSTEM	411	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	SNU738	N	0	0	5	Y
MSH2	INQLPNVIK	OVARY	411	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	TYKNU	N	0	0	5	Y
MSH2	KALEKHEGK	LIVER	419	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	JHH7	N	4	0	0	N
MSH2	KALEKHEGK	STOMACH	419	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	NCCSTCK140	N	4	0	0	N
MSH2	KALEKHEGK	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	419	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	SKM1	N	4	0	0	N
MSH2	KALEKHEGK	LARGE_INTESTINE	419	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	SNU283	N	4	0	0	N
MSH2	KALEKHEGK	CENTRAL_NERVOUS_SYSTEM	419	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	SNU738	N	4	0	0	N
MSH2	KALEKHEGK	OVARY	419	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	TYKNU	N	4	0	0	N
MSH2	LPNVIKALE	LIVER	414	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	JHH7	N	2	0	2	N
MSH2	LPNVIKALE	STOMACH	414	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	NCCSTCK140	N	2	0	2	N
MSH2	LPNVIKALE	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	414	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	SKM1	N	2	0	2	N
MSH2	LPNVIKALE	LARGE_INTESTINE	414	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	SNU283	N	2	0	2	N
MSH2	LPNVIKALE	CENTRAL_NERVOUS_SYSTEM	414	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	SNU738	N	2	0	2	N
MSH2	LPNVIKALE	OVARY	414	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	TYKNU	N	2	0	2	N
MSH2	NQLPNVIKA	LIVER	412	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	JHH7	Y	7	9	0	N
MSH2	NQLPNVIKA	STOMACH	412	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	NCCSTCK140	Y	7	9	0	N
MSH2	NQLPNVIKA	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	412	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	SKM1	Y	7	9	0	N
MSH2	NQLPNVIKA	LARGE_INTESTINE	412	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	SNU283	Y	7	9	0	N
MSH2	NQLPNVIKA	CENTRAL_NERVOUS_SYSTEM	412	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	SNU738	Y	7	9	0	N
MSH2	NQLPNVIKA	OVARY	412	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	TYKNU	Y	7	9	0	N
MSH2	NVIKALEKH	LIVER	416	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	JHH7	N	1	0	0	N
MSH2	NVIKALEKH	STOMACH	416	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	NCCSTCK140	N	1	0	0	N
MSH2	NVIKALEKH	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	416	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	SKM1	N	1	0	0	N
MSH2	NVIKALEKH	LARGE_INTESTINE	416	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	SNU283	N	1	0	0	N
MSH2	NVIKALEKH	CENTRAL_NERVOUS_SYSTEM	416	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	SNU738	N	1	0	0	N
MSH2	NVIKALEKH	OVARY	416	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	TYKNU	N	1	0	0	N
MSH2	PNVIKALEK	LIVER	415	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	JHH7	N	0	0	0	N
MSH2	PNVIKALEK	STOMACH	415	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	NCCSTCK140	N	0	0	0	N
MSH2	PNVIKALEK	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	415	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	SKM1	N	0	0	0	N
MSH2	PNVIKALEK	LARGE_INTESTINE	415	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	SNU283	N	0	0	0	N
MSH2	PNVIKALEK	CENTRAL_NERVOUS_SYSTEM	415	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	SNU738	N	0	0	0	N
MSH2	PNVIKALEK	OVARY	415	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	TYKNU	N	0	0	0	N
MSH2	QLPNVIKAL	LIVER	413	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	JHH7	Y	15	12	0	N
MSH2	QLPNVIKAL	STOMACH	413	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	NCCSTCK140	Y	15	12	0	N
MSH2	QLPNVIKAL	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	413	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	SKM1	Y	15	12	0	N
MSH2	QLPNVIKAL	LARGE_INTESTINE	413	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	SNU283	Y	15	12	0	N
MSH2	QLPNVIKAL	CENTRAL_NERVOUS_SYSTEM	413	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	SNU738	Y	15	12	0	N
MSH2	QLPNVIKAL	OVARY	413	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	TYKNU	Y	15	12	0	N
MSH2	VIKALEKHE	LIVER	417	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	JHH7	N	0	0	0	N
MSH2	VIKALEKHE	STOMACH	417	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	NCCSTCK140	N	0	0	0	N
MSH2	VIKALEKHE	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	417	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	SKM1	N	0	0	0	N
MSH2	VIKALEKHE	LARGE_INTESTINE	417	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	SNU283	N	0	0	0	N
MSH2	VIKALEKHE	CENTRAL_NERVOUS_SYSTEM	417	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	SNU738	N	0	0	0	N
MSH2	VIKALEKHE	OVARY	417	p.Q419K	c.1255C>A	Missense_Mutation	1	0.66	TYKNU	N	0	0	0	N