Cancertope: In silico Platform for designing genome-based Personalized immunotherapy or Vaccine against Cancer

Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Browse Results ...

The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE

Protein	Neoepitopes	Tissue	Position	Prot Mutation	cDNA Mutation	Mutation Type	Num Mismatch	Promiscuity (%)	Cell Line	CTL	MHC I	NHLApred	MHC II	Bcell
Result		Search:
PRKDC	AHKRLQRAP	BONE	2681	p.SER2685del	c.8053_8061delAGTGAAAGG	In_Frame_Del	3	0.11	HS822T	N	0	0	0	N
PRKDC	FAHKRLQRA	BONE	2680	p.SER2685del	c.8053_8061delAGTGAAAGG	In_Frame_Del	3	0.11	HS822T	N	9	0	2	N
PRKDC	HKRLQRAPL	BONE	2682	p.SER2685del	c.8053_8061delAGTGAAAGG	In_Frame_Del	2	0.11	HS822T	N	4	0	0	N
PRKDC	KRLQRAPLK	BONE	2683	p.SER2685del	c.8053_8061delAGTGAAAGG	In_Frame_Del	1	0.11	HS822T	Y	3	11	0	N
PRKDC	LFAHKRLQR	BONE	2679	p.SER2685del	c.8053_8061delAGTGAAAGG	In_Frame_Del	2	0.11	HS822T	N	2	0	15	N
PRKDC	LLFAHKRLQ	BONE	2678	p.SER2685del	c.8053_8061delAGTGAAAGG	In_Frame_Del	2	0.11	HS822T	N	0	0	28	Y
PRKDC	SLLFAHKRL	BONE	2677	p.SER2685del	c.8053_8061delAGTGAAAGG	In_Frame_Del	1	0.11	HS822T	Y	11	10	0	Y
PRKDC	GPPQEEDSV	ENDOMETRIUM	2109	p.G2113del	c.6338_6340delGAG	In_Frame_Del	3	0.66	EN	N	13	0	0	N
PRKDC	GPPQEEDSV	AUTONOMIC_GANGLIA	2109	p.G2113del	c.6338_6340delGAG	In_Frame_Del	3	0.66	KPNSI9S	N	13	0	0	N
PRKDC	GPPQEEDSV	OVARY	2109	p.G2113del	c.6338_6340delGAG	In_Frame_Del	3	0.66	MCAS	N	13	0	0	N
PRKDC	GPPQEEDSV	LUNG	2109	p.G2113del	c.6338_6340delGAG	In_Frame_Del	3	0.66	RERFLCKJ	N	13	0	0	N
PRKDC	GPPQEEDSV	LIVER	2109	p.G2113del	c.6338_6340delGAG	In_Frame_Del	3	0.66	SNU449	N	13	0	0	N
PRKDC	GPPQEEDSV	OESOPHAGUS	2109	p.G2113del	c.6338_6340delGAG	In_Frame_Del	3	0.66	TE6	N	13	0	0	N
PRKDC	HRSLGPPQE	ENDOMETRIUM	2105	p.G2113del	c.6338_6340delGAG	In_Frame_Del	1	0.66	EN	N	1	0	0	N
PRKDC	HRSLGPPQE	AUTONOMIC_GANGLIA	2105	p.G2113del	c.6338_6340delGAG	In_Frame_Del	1	0.66	KPNSI9S	N	1	0	0	N
PRKDC	HRSLGPPQE	OVARY	2105	p.G2113del	c.6338_6340delGAG	In_Frame_Del	1	0.66	MCAS	N	1	0	0	N
PRKDC	HRSLGPPQE	LUNG	2105	p.G2113del	c.6338_6340delGAG	In_Frame_Del	1	0.66	RERFLCKJ	N	1	0	0	N
PRKDC	HRSLGPPQE	LIVER	2105	p.G2113del	c.6338_6340delGAG	In_Frame_Del	1	0.66	SNU449	N	1	0	0	N
PRKDC	HRSLGPPQE	OESOPHAGUS	2105	p.G2113del	c.6338_6340delGAG	In_Frame_Del	1	0.66	TE6	N	1	0	0	N
PRKDC	LGPPQEEDS	ENDOMETRIUM	2108	p.G2113del	c.6338_6340delGAG	In_Frame_Del	3	0.66	EN	N	1	0	0	N
PRKDC	LGPPQEEDS	AUTONOMIC_GANGLIA	2108	p.G2113del	c.6338_6340delGAG	In_Frame_Del	3	0.66	KPNSI9S	N	1	0	0	N
PRKDC	LGPPQEEDS	OVARY	2108	p.G2113del	c.6338_6340delGAG	In_Frame_Del	3	0.66	MCAS	N	1	0	0	N
PRKDC	LGPPQEEDS	LUNG	2108	p.G2113del	c.6338_6340delGAG	In_Frame_Del	3	0.66	RERFLCKJ	N	1	0	0	N
PRKDC	LGPPQEEDS	LIVER	2108	p.G2113del	c.6338_6340delGAG	In_Frame_Del	3	0.66	SNU449	N	1	0	0	N
PRKDC	LGPPQEEDS	OESOPHAGUS	2108	p.G2113del	c.6338_6340delGAG	In_Frame_Del	3	0.66	TE6	N	1	0	0	N
PRKDC	PPQEEDSVP	ENDOMETRIUM	2110	p.G2113del	c.6338_6340delGAG	In_Frame_Del	2	0.66	EN	N	0	0	0	N
PRKDC	PPQEEDSVP	AUTONOMIC_GANGLIA	2110	p.G2113del	c.6338_6340delGAG	In_Frame_Del	2	0.66	KPNSI9S	N	0	0	0	N
PRKDC	PPQEEDSVP	OVARY	2110	p.G2113del	c.6338_6340delGAG	In_Frame_Del	2	0.66	MCAS	N	0	0	0	N
PRKDC	PPQEEDSVP	LUNG	2110	p.G2113del	c.6338_6340delGAG	In_Frame_Del	2	0.66	RERFLCKJ	N	0	0	0	N
PRKDC	PPQEEDSVP	LIVER	2110	p.G2113del	c.6338_6340delGAG	In_Frame_Del	2	0.66	SNU449	N	0	0	0	N
PRKDC	PPQEEDSVP	OESOPHAGUS	2110	p.G2113del	c.6338_6340delGAG	In_Frame_Del	2	0.66	TE6	N	0	0	0	N
PRKDC	PQEEDSVPR	ENDOMETRIUM	2111	p.G2113del	c.6338_6340delGAG	In_Frame_Del	2	0.66	EN	N	0	0	0	N
PRKDC	PQEEDSVPR	AUTONOMIC_GANGLIA	2111	p.G2113del	c.6338_6340delGAG	In_Frame_Del	2	0.66	KPNSI9S	N	0	0	0	N
PRKDC	PQEEDSVPR	OVARY	2111	p.G2113del	c.6338_6340delGAG	In_Frame_Del	2	0.66	MCAS	N	0	0	0	N
PRKDC	PQEEDSVPR	LUNG	2111	p.G2113del	c.6338_6340delGAG	In_Frame_Del	2	0.66	RERFLCKJ	N	0	0	0	N
PRKDC	PQEEDSVPR	LIVER	2111	p.G2113del	c.6338_6340delGAG	In_Frame_Del	2	0.66	SNU449	N	0	0	0	N
PRKDC	PQEEDSVPR	OESOPHAGUS	2111	p.G2113del	c.6338_6340delGAG	In_Frame_Del	2	0.66	TE6	N	0	0	0	N
PRKDC	QEEDSVPRD	ENDOMETRIUM	2112	p.G2113del	c.6338_6340delGAG	In_Frame_Del	1	0.66	EN	N	0	0	0	N
PRKDC	QEEDSVPRD	AUTONOMIC_GANGLIA	2112	p.G2113del	c.6338_6340delGAG	In_Frame_Del	1	0.66	KPNSI9S	N	0	0	0	N
PRKDC	QEEDSVPRD	OVARY	2112	p.G2113del	c.6338_6340delGAG	In_Frame_Del	1	0.66	MCAS	N	0	0	0	N
PRKDC	QEEDSVPRD	LUNG	2112	p.G2113del	c.6338_6340delGAG	In_Frame_Del	1	0.66	RERFLCKJ	N	0	0	0	N
PRKDC	QEEDSVPRD	LIVER	2112	p.G2113del	c.6338_6340delGAG	In_Frame_Del	1	0.66	SNU449	N	0	0	0	N
PRKDC	QEEDSVPRD	OESOPHAGUS	2112	p.G2113del	c.6338_6340delGAG	In_Frame_Del	1	0.66	TE6	N	0	0	0	N
PRKDC	RSLGPPQEE	ENDOMETRIUM	2106	p.G2113del	c.6338_6340delGAG	In_Frame_Del	1	0.66	EN	N	0	0	0	N
PRKDC	RSLGPPQEE	AUTONOMIC_GANGLIA	2106	p.G2113del	c.6338_6340delGAG	In_Frame_Del	1	0.66	KPNSI9S	N	0	0	0	N
PRKDC	RSLGPPQEE	OVARY	2106	p.G2113del	c.6338_6340delGAG	In_Frame_Del	1	0.66	MCAS	N	0	0	0	N
PRKDC	RSLGPPQEE	LUNG	2106	p.G2113del	c.6338_6340delGAG	In_Frame_Del	1	0.66	RERFLCKJ	N	0	0	0	N
PRKDC	RSLGPPQEE	LIVER	2106	p.G2113del	c.6338_6340delGAG	In_Frame_Del	1	0.66	SNU449	N	0	0	0	N
PRKDC	RSLGPPQEE	OESOPHAGUS	2106	p.G2113del	c.6338_6340delGAG	In_Frame_Del	1	0.66	TE6	N	0	0	0	N
PRKDC	SLGPPQEED	ENDOMETRIUM	2107	p.G2113del	c.6338_6340delGAG	In_Frame_Del	2	0.66	EN	N	0	0	0	N
PRKDC	SLGPPQEED	AUTONOMIC_GANGLIA	2107	p.G2113del	c.6338_6340delGAG	In_Frame_Del	2	0.66	KPNSI9S	N	0	0	0	N
PRKDC	SLGPPQEED	OVARY	2107	p.G2113del	c.6338_6340delGAG	In_Frame_Del	2	0.66	MCAS	N	0	0	0	N
PRKDC	SLGPPQEED	LUNG	2107	p.G2113del	c.6338_6340delGAG	In_Frame_Del	2	0.66	RERFLCKJ	N	0	0	0	N
PRKDC	SLGPPQEED	LIVER	2107	p.G2113del	c.6338_6340delGAG	In_Frame_Del	2	0.66	SNU449	N	0	0	0	N
PRKDC	SLGPPQEED	OESOPHAGUS	2107	p.G2113del	c.6338_6340delGAG	In_Frame_Del	2	0.66	TE6	N	0	0	0	N