Cancertope: In silico Platform for designing genome-based Personalized immunotherapy or Vaccine against Cancer

Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Browse Results ...

The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE

Protein	Neoepitopes	Tissue	Position	Prot Mutation	cDNA Mutation	Mutation Type	Num Mismatch	Promiscuity (%)	Cell Line	CTL	MHC I	NHLApred	MHC II	Bcell
Result		Search:
TTBK1	APPRLPHNP	LARGE_INTESTINE	437	p.A437fs	c.1309_1310insC	Frame_Shift_Ins	3	0.11	SNUC4	N	0	0	0	N
TTBK1	FSALPEGEQ	LARGE_INTESTINE	448	p.A437fs	c.1309_1310insC	Frame_Shift_Ins	5	0.11	SNUC4	N	2	0	0	N
TTBK1	HNPSPFSAL	LARGE_INTESTINE	443	p.A437fs	c.1309_1310insC	Frame_Shift_Ins	5	0.11	SNUC4	Y	10	14	0	N
TTBK1	LPHNPSPFS	LARGE_INTESTINE	441	p.A437fs	c.1309_1310insC	Frame_Shift_Ins	4	0.11	SNUC4	N	5	0	0	N
TTBK1	NPSPFSALP	LARGE_INTESTINE	444	p.A437fs	c.1309_1310insC	Frame_Shift_Ins	5	0.11	SNUC4	N	0	0	0	N
TTBK1	PFSALPEGE	LARGE_INTESTINE	447	p.A437fs	c.1309_1310insC	Frame_Shift_Ins	5	0.11	SNUC4	N	0	0	0	N
TTBK1	PHNPSPFSA	LARGE_INTESTINE	442	p.A437fs	c.1309_1310insC	Frame_Shift_Ins	5	0.11	SNUC4	N	0	0	0	N
TTBK1	PPRLPHNPS	LARGE_INTESTINE	438	p.A437fs	c.1309_1310insC	Frame_Shift_Ins	3	0.11	SNUC4	N	1	0	0	N
TTBK1	PRLPHNPSP	LARGE_INTESTINE	439	p.A437fs	c.1309_1310insC	Frame_Shift_Ins	4	0.11	SNUC4	N	0	0	0	N
TTBK1	PSPFSALPE	LARGE_INTESTINE	445	p.A437fs	c.1309_1310insC	Frame_Shift_Ins	5	0.11	SNUC4	N	0	0	0	N
TTBK1	PVRAPPRLP	LARGE_INTESTINE	434	p.A437fs	c.1309_1310insC	Frame_Shift_Ins	2	0.11	SNUC4	N	0	0	0	N
TTBK1	RAPPRLPHN	LARGE_INTESTINE	436	p.A437fs	c.1309_1310insC	Frame_Shift_Ins	4	0.11	SNUC4	N	3	0	0	N
TTBK1	RLPHNPSPF	LARGE_INTESTINE	440	p.A437fs	c.1309_1310insC	Frame_Shift_Ins	4	0.11	SNUC4	N	9	0	0	N
TTBK1	SALPEGEQP	LARGE_INTESTINE	449	p.A437fs	c.1309_1310insC	Frame_Shift_Ins	5	0.11	SNUC4	N	0	0	0	N
TTBK1	SPFSALPEG	LARGE_INTESTINE	446	p.A437fs	c.1309_1310insC	Frame_Shift_Ins	5	0.11	SNUC4	N	1	0	0	N
TTBK1	SPVRAPPRL	LARGE_INTESTINE	433	p.A437fs	c.1309_1310insC	Frame_Shift_Ins	2	0.11	SNUC4	Y	19	9	0	N
TTBK1	SSPVRAPPR	LARGE_INTESTINE	432	p.A437fs	c.1309_1310insC	Frame_Shift_Ins	1	0.11	SNUC4	N	3	0	0	Y
TTBK1	VRAPPRLPH	LARGE_INTESTINE	435	p.A437fs	c.1309_1310insC	Frame_Shift_Ins	3	0.11	SNUC4	N	2	0	20	N
TTBK1	AAMFRVVNV	SKIN	335	p.G339R	c.1015G>A	Missense_Mutation	1	0.11	WM88	Y	9	13	0	N
TTBK1	ADGDLEPQE	BREAST	823	p.E830Q	c.2488G>C	Missense_Mutation	1	0.11	EVSAT	N	0	0	0	N
TTBK1	ADGLVELPE	LUNG	465	p.R468L	c.1403G>T	Missense_Mutation	1	0.11	NCIH1339	N	0	0	0	N
TTBK1	ADTDALLST	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	313	p.G314D	c.941G>A	Missense_Mutation	1	0.11	PF382	N	2	0	0	N
TTBK1	AFDWEKADT	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	307	p.G314D	c.941G>A	Missense_Mutation	1	0.11	PF382	N	1	0	0	N
TTBK1	AFLSTSTST	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	317	p.L318F	c.952C>T	Missense_Mutation	1	0.11	OCIAML5	N	2	0	0	N
TTBK1	AGFRGMVRY	OVARY	197	p.T202M	c.605C>T	Missense_Mutation	1	0.11	OC316	N	6	0	0	N
TTBK1	AGTDAFLST	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	313	p.L318F	c.952C>T	Missense_Mutation	1	0.11	OCIAML5	N	2	0	0	N
TTBK1	ALGEVLGPG	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	777	p.R785G	c.2353C>G	Missense_Mutation	1	0.11	HUT78	N	0	0	0	N
TTBK1	AMFRVVNVT	SKIN	336	p.G339R	c.1015G>A	Missense_Mutation	1	0.11	WM88	Y	6	13	0	N
TTBK1	APQDSPTTP	SKIN	437	p.P439Q	c.1316C>A	Missense_Mutation	1	0.11	MDAMB435S	N	0	0	0	N
TTBK1	APVQLQANG	SKIN	723	p.P727L	c.2180C>T	Missense_Mutation	1	0.11	SKMEL24	N	0	0	0	N
TTBK1	ARLLNRVQR	ENDOMETRIUM	699	p.R706Q	c.2117G>A	Missense_Mutation	1	0.11	HEC1B	Y	3	10	0	N
TTBK1	CGRNKKFNY	SOFT_TISSUE	96	p.E100K	c.298G>A	Missense_Mutation	1	0.11	GCT	N	5	0	0	N
TTBK1	CRFVGCGRN	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	91	p.I94V	c.280A>G	Missense_Mutation	1	0.11	JM1	N	2	0	0	N
TTBK1	DAFLSTSTS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	316	p.L318F	c.952C>T	Missense_Mutation	1	0.11	OCIAML5	N	3	0	0	N
TTBK1	DGDLEPQEG	BREAST	824	p.E830Q	c.2488G>C	Missense_Mutation	1	0.11	EVSAT	N	0	0	0	N
TTBK1	DGLVELPER	LUNG	466	p.R468L	c.1403G>T	Missense_Mutation	1	0.11	NCIH1339	N	1	0	0	N
TTBK1	DHVCRFVGC	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	88	p.I94V	c.280A>G	Missense_Mutation	1	0.11	JM1	N	2	0	0	N
TTBK1	DLEPQEGSK	BREAST	826	p.E830Q	c.2488G>C	Missense_Mutation	1	0.11	EVSAT	N	4	0	0	Y
TTBK1	DLSDYRERV	STOMACH	691	p.A699V	c.2096C>T	Missense_Mutation	1	0.11	SH10TC	Y	3	9	0	N
TTBK1	DMKKSLVTA	SKIN	843	p.P848L	c.2543C>T	Missense_Mutation	1	0.11	WM88	N	1	0	0	N
TTBK1	DMKKSSVTA	PANCREAS	843	p.P848S	c.2542C>T	Missense_Mutation	1	0.11	PANC0203	N	1	0	0	N
TTBK1	DTDALLSTS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	314	p.G314D	c.941G>A	Missense_Mutation	1	0.11	PF382	N	1	0	0	Y
TTBK1	DWEKADTDA	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	309	p.G314D	c.941G>A	Missense_Mutation	1	0.11	PF382	N	0	0	0	N
TTBK1	DYFTKPYYQ	LUNG	279	p.D285Y	c.853G>T	Missense_Mutation	1	0.11	NCIH2110	N	1	0	0	Y
TTBK1	DYRERVRLL	STOMACH	694	p.A699V	c.2096C>T	Missense_Mutation	1	0.11	SH10TC	Y	9	9	0	N
TTBK1	EAFDWEKAD	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	306	p.G314D	c.941G>A	Missense_Mutation	1	0.11	PF382	N	0	0	0	N
TTBK1	EKADTDALL	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	311	p.G314D	c.941G>A	Missense_Mutation	1	0.11	PF382	N	4	0	0	N
TTBK1	EKAGTDAFL	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	311	p.L318F	c.952C>T	Missense_Mutation	1	0.11	OCIAML5	N	4	0	0	N
TTBK1	EPQEGSKTL	BREAST	828	p.E830Q	c.2488G>C	Missense_Mutation	1	0.11	EVSAT	N	18	0	0	N
TTBK1	ERLSTADGL	LUNG	460	p.R468L	c.1403G>T	Missense_Mutation	1	0.11	NCIH1339	Y	6	11	0	N
TTBK1	ERVRLLNRV	STOMACH	697	p.A699V	c.2096C>T	Missense_Mutation	1	0.11	SH10TC	Y	5	11	0	N
TTBK1	ESGRLSTAD	BONE	458	p.E460G	c.1379A>G	Missense_Mutation	1	0.11	HS819T	N	0	0	0	N
TTBK1	EVLGPGSGS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	780	p.R785G	c.2353C>G	Missense_Mutation	1	0.11	HUT78	N	1	0	0	N
TTBK1	FDWEKADTD	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	308	p.G314D	c.941G>A	Missense_Mutation	1	0.11	PF382	N	2	0	0	N
TTBK1	FIGCGRNKK	SOFT_TISSUE	93	p.E100K	c.298G>A	Missense_Mutation	1	0.11	GCT	N	5	0	9	N
TTBK1	FLSTSTSTP	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	318	p.L318F	c.952C>T	Missense_Mutation	1	0.11	OCIAML5	N	3	0	4	N
TTBK1	FRGMVRYAS	OVARY	199	p.T202M	c.605C>T	Missense_Mutation	1	0.11	OC316	N	5	0	38	N
TTBK1	FRVVNVTPV	SKIN	338	p.G339R	c.1015G>A	Missense_Mutation	1	0.11	WM88	Y	9	11	33	N
TTBK1	FSVVPPFEV	LUNG	664	p.A667V	c.2000C>T	Missense_Mutation	1	0.11	LCLC97TM1	N	10	0	5	Y
TTBK1	FTKPYYQLI	LUNG	281	p.D285Y	c.853G>T	Missense_Mutation	1	0.11	NCIH2110	Y	9	15	0	Y
TTBK1	FVGCGRNEK	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	93	p.I94V	c.280A>G	Missense_Mutation	1	0.11	JM1	N	5	0	19	N
TTBK1	GCGRNKKFN	SOFT_TISSUE	95	p.E100K	c.298G>A	Missense_Mutation	1	0.11	GCT	N	0	0	0	N
TTBK1	GDLEPQEGS	BREAST	825	p.E830Q	c.2488G>C	Missense_Mutation	1	0.11	EVSAT	N	2	0	0	N
TTBK1	GDMKKSLVT	SKIN	842	p.P848L	c.2543C>T	Missense_Mutation	1	0.11	WM88	N	4	0	0	N
TTBK1	GDMKKSSVT	PANCREAS	842	p.P848S	c.2542C>T	Missense_Mutation	1	0.11	PANC0203	N	4	0	0	N
TTBK1	GEVLGPGSG	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	779	p.R785G	c.2353C>G	Missense_Mutation	1	0.11	HUT78	N	1	0	0	N
TTBK1	GFRGMVRYA	OVARY	198	p.T202M	c.605C>T	Missense_Mutation	1	0.11	OC316	Y	1	10	0	N
TTBK1	GKDHVCRFV	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	86	p.I94V	c.280A>G	Missense_Mutation	1	0.11	JM1	N	2	0	0	N
TTBK1	GLVELPERR	LUNG	467	p.R468L	c.1403G>T	Missense_Mutation	1	0.11	NCIH1339	N	6	0	0	Y
TTBK1	GMVRYASVN	OVARY	201	p.T202M	c.605C>T	Missense_Mutation	1	0.11	OC316	N	1	0	0	N
TTBK1	GPGSGSSSE	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	783	p.R785G	c.2353C>G	Missense_Mutation	1	0.11	HUT78	N	0	0	0	N
TTBK1	GPRSGSGSE	LARGE_INTESTINE	783	p.S789G	c.2365A>G	Missense_Mutation	1	0.11	RKO	N	0	0	0	Y
TTBK1	GRLSTADGR	BONE	460	p.E460G	c.1379A>G	Missense_Mutation	1	0.11	HS819T	N	3	0	0	N
TTBK1	GRNKKFNYV	SOFT_TISSUE	97	p.E100K	c.298G>A	Missense_Mutation	1	0.11	GCT	Y	3	9	0	N
TTBK1	GSEGSERST	LARGE_INTESTINE	789	p.S789G	c.2365A>G	Missense_Mutation	1	0.11	RKO	N	2	0	0	N
TTBK1	GSGSEGSER	LARGE_INTESTINE	787	p.S789G	c.2365A>G	Missense_Mutation	1	0.11	RKO	N	3	0	0	N
TTBK1	GSGSSSEGS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	785	p.R785G	c.2353C>G	Missense_Mutation	1	0.11	HUT78	N	0	0	0	N
TTBK1	GTDAFLSTS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	314	p.L318F	c.952C>T	Missense_Mutation	1	0.11	OCIAML5	N	2	0	0	N
TTBK1	HVCRFVGCG	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	89	p.I94V	c.280A>G	Missense_Mutation	1	0.11	JM1	Y	0	9	0	N
TTBK1	IGCGRNKKF	SOFT_TISSUE	94	p.E100K	c.298G>A	Missense_Mutation	1	0.11	GCT	N	7	0	0	N
TTBK1	KADTDALLS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	312	p.G314D	c.941G>A	Missense_Mutation	1	0.11	PF382	N	2	0	0	Y
TTBK1	KAGTDAFLS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	312	p.L318F	c.952C>T	Missense_Mutation	1	0.11	OCIAML5	N	1	0	0	Y
TTBK1	KDHVCRFVG	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	87	p.I94V	c.280A>G	Missense_Mutation	1	0.11	JM1	N	1	0	0	N
TTBK1	KKFNYVVMQ	SOFT_TISSUE	100	p.E100K	c.298G>A	Missense_Mutation	1	0.11	GCT	N	1	0	0	N
TTBK1	KKSLVTAEL	SKIN	845	p.P848L	c.2543C>T	Missense_Mutation	1	0.11	WM88	N	5	0	0	N
TTBK1	KKSSVTAEL	PANCREAS	845	p.P848S	c.2542C>T	Missense_Mutation	1	0.11	PANC0203	Y	6	14	0	N
TTBK1	KPYYQLIMS	LUNG	283	p.D285Y	c.853G>T	Missense_Mutation	1	0.11	NCIH2110	N	7	0	0	N
TTBK1	KSLVTAELA	SKIN	846	p.P848L	c.2543C>T	Missense_Mutation	1	0.11	WM88	N	2	0	0	N
TTBK1	KSSVTAELA	PANCREAS	846	p.P848S	c.2542C>T	Missense_Mutation	1	0.11	PANC0203	N	2	0	0	N
TTBK1	LAPVQLQAN	SKIN	722	p.P727L	c.2180C>T	Missense_Mutation	1	0.11	SKMEL24	N	1	0	0	N
TTBK1	LDYFTKPYY	LUNG	278	p.D285Y	c.853G>T	Missense_Mutation	1	0.11	NCIH2110	N	6	0	0	Y
TTBK1	LEPQEGSKT	BREAST	827	p.E830Q	c.2488G>C	Missense_Mutation	1	0.11	EVSAT	N	6	0	0	N
TTBK1	LGEVLGPGS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	778	p.R785G	c.2353C>G	Missense_Mutation	1	0.11	HUT78	N	0	0	0	N
TTBK1	LGPGSGSSS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	782	p.R785G	c.2353C>G	Missense_Mutation	1	0.11	HUT78	N	1	0	0	N
TTBK1	LGPRSGSGS	LARGE_INTESTINE	782	p.S789G	c.2365A>G	Missense_Mutation	1	0.11	RKO	N	1	0	2	Y
TTBK1	LLNRVQRVG	ENDOMETRIUM	701	p.R706Q	c.2117G>A	Missense_Mutation	1	0.11	HEC1B	N	0	0	7	N
TTBK1	LNRVQRVGF	ENDOMETRIUM	702	p.R706Q	c.2117G>A	Missense_Mutation	1	0.11	HEC1B	N	4	0	5	N
TTBK1	LQANGKEEE	SKIN	727	p.P727L	c.2180C>T	Missense_Mutation	1	0.11	SKMEL24	N	0	0	1	N
TTBK1	LSDYRERVR	STOMACH	692	p.A699V	c.2096C>T	Missense_Mutation	1	0.11	SH10TC	N	4	0	0	N
TTBK1	LSTADGLVE	LUNG	462	p.R468L	c.1403G>T	Missense_Mutation	1	0.11	NCIH1339	N	0	0	0	N
TTBK1	LVELPERRS	LUNG	468	p.R468L	c.1403G>T	Missense_Mutation	1	0.11	NCIH1339	N	1	0	3	N
TTBK1	LVTAELAPD	SKIN	848	p.P848L	c.2543C>T	Missense_Mutation	1	0.11	WM88	N	0	0	4	N
TTBK1	MADGDLEPQ	BREAST	822	p.E830Q	c.2488G>C	Missense_Mutation	1	0.11	EVSAT	N	0	0	0	N
TTBK1	MFRVVNVTP	SKIN	337	p.G339R	c.1015G>A	Missense_Mutation	1	0.11	WM88	N	0	0	2	N
TTBK1	MKKSLVTAE	SKIN	844	p.P848L	c.2543C>T	Missense_Mutation	1	0.11	WM88	N	0	0	2	N
TTBK1	MKKSSVTAE	PANCREAS	844	p.P848S	c.2542C>T	Missense_Mutation	1	0.11	PANC0203	N	0	0	2	N
TTBK1	MVRYASVNA	OVARY	202	p.T202M	c.605C>T	Missense_Mutation	1	0.11	OC316	N	2	0	26	N
TTBK1	NKKFNYVVM	SOFT_TISSUE	99	p.E100K	c.298G>A	Missense_Mutation	1	0.11	GCT	N	4	0	0	N
TTBK1	NRVQRVGFS	ENDOMETRIUM	703	p.R706Q	c.2117G>A	Missense_Mutation	1	0.11	HEC1B	N	3	0	0	N
TTBK1	NSPESGRLS	BONE	455	p.E460G	c.1379A>G	Missense_Mutation	1	0.11	HS819T	N	1	0	0	N
TTBK1	NVAGFRGMV	OVARY	195	p.T202M	c.605C>T	Missense_Mutation	1	0.11	OC316	Y	2	11	0	N
TTBK1	PESGRLSTA	BONE	457	p.E460G	c.1379A>G	Missense_Mutation	1	0.11	HS819T	Y	2	9	0	N
TTBK1	PGDMKKSLV	SKIN	841	p.P848L	c.2543C>T	Missense_Mutation	1	0.11	WM88	N	1	0	0	N
TTBK1	PGDMKKSSV	PANCREAS	841	p.P848S	c.2542C>T	Missense_Mutation	1	0.11	PANC0203	N	1	0	0	N
TTBK1	PGSGSSSEG	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	784	p.R785G	c.2353C>G	Missense_Mutation	1	0.11	HUT78	N	0	0	0	N
TTBK1	PLAPVQLQA	SKIN	721	p.P727L	c.2180C>T	Missense_Mutation	1	0.11	SKMEL24	N	1	0	0	N
TTBK1	PQDSPTTPV	SKIN	438	p.P439Q	c.1316C>A	Missense_Mutation	1	0.11	MDAMB435S	N	1	0	0	N
TTBK1	PQEGSKTLV	BREAST	829	p.E830Q	c.2488G>C	Missense_Mutation	1	0.11	EVSAT	N	0	0	0	N
TTBK1	PQRQVFSVV	LUNG	659	p.A667V	c.2000C>T	Missense_Mutation	1	0.11	LCLC97TM1	N	1	0	0	N
TTBK1	PRSGSGSEG	LARGE_INTESTINE	784	p.S789G	c.2365A>G	Missense_Mutation	1	0.11	RKO	N	0	0	0	N
TTBK1	PSSPVRAPQ	SKIN	431	p.P439Q	c.1316C>A	Missense_Mutation	1	0.11	MDAMB435S	N	0	0	0	N
TTBK1	PVQLQANGK	SKIN	724	p.P727L	c.2180C>T	Missense_Mutation	1	0.11	SKMEL24	N	2	0	0	N
TTBK1	PVRAPQDSP	SKIN	434	p.P439Q	c.1316C>A	Missense_Mutation	1	0.11	MDAMB435S	N	0	0	0	N
TTBK1	PYYQLIMSV	LUNG	284	p.D285Y	c.853G>T	Missense_Mutation	1	0.11	NCIH2110	N	3	0	0	N
TTBK1	QDSPTTPVR	SKIN	439	p.P439Q	c.1316C>A	Missense_Mutation	1	0.11	MDAMB435S	N	0	0	0	N
TTBK1	QEGSKTLVL	BREAST	830	p.E830Q	c.2488G>C	Missense_Mutation	1	0.11	EVSAT	N	9	0	0	N
TTBK1	QLQANGKEE	SKIN	726	p.P727L	c.2180C>T	Missense_Mutation	1	0.11	SKMEL24	N	0	0	0	N
TTBK1	QRQVFSVVP	LUNG	660	p.A667V	c.2000C>T	Missense_Mutation	1	0.11	LCLC97TM1	N	1	0	0	N
TTBK1	QRVGFSHML	ENDOMETRIUM	706	p.R706Q	c.2117G>A	Missense_Mutation	1	0.11	HEC1B	Y	9	9	0	N
TTBK1	QTAAMFRVV	SKIN	333	p.G339R	c.1015G>A	Missense_Mutation	1	0.11	WM88	Y	3	14	0	N
TTBK1	QVFSVVPPF	LUNG	662	p.A667V	c.2000C>T	Missense_Mutation	1	0.11	LCLC97TM1	Y	7	9	0	Y
TTBK1	QVPLAPVQL	SKIN	719	p.P727L	c.2180C>T	Missense_Mutation	1	0.11	SKMEL24	Y	7	9	0	N
TTBK1	RAPQDSPTT	SKIN	436	p.P439Q	c.1316C>A	Missense_Mutation	1	0.11	MDAMB435S	N	3	0	0	N
TTBK1	RARLLNRVQ	ENDOMETRIUM	698	p.R706Q	c.2117G>A	Missense_Mutation	1	0.11	HEC1B	N	1	0	0	N
TTBK1	RERVRLLNR	STOMACH	696	p.A699V	c.2096C>T	Missense_Mutation	1	0.11	SH10TC	Y	3	10	0	N
TTBK1	RFIGCGRNK	SOFT_TISSUE	92	p.E100K	c.298G>A	Missense_Mutation	1	0.11	GCT	N	0	0	0	N
TTBK1	RFVGCGRNE	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	92	p.I94V	c.280A>G	Missense_Mutation	1	0.11	JM1	N	0	0	0	N
TTBK1	RGMVRYASV	OVARY	200	p.T202M	c.605C>T	Missense_Mutation	1	0.11	OC316	Y	8	10	0	N
TTBK1	RLLNRVQRV	ENDOMETRIUM	700	p.R706Q	c.2117G>A	Missense_Mutation	1	0.11	HEC1B	Y	13	11	0	N
TTBK1	RLSTADGLV	LUNG	461	p.R468L	c.1403G>T	Missense_Mutation	1	0.11	NCIH1339	Y	6	11	0	N
TTBK1	RNKKFNYVV	SOFT_TISSUE	98	p.E100K	c.298G>A	Missense_Mutation	1	0.11	GCT	N	4	0	0	N
TTBK1	RNVAGFRGM	OVARY	194	p.T202M	c.605C>T	Missense_Mutation	1	0.11	OC316	Y	6	15	0	N
TTBK1	RQTAAMFRV	SKIN	332	p.G339R	c.1015G>A	Missense_Mutation	1	0.11	WM88	Y	10	11	0	N
TTBK1	RQVFSVVPP	LUNG	661	p.A667V	c.2000C>T	Missense_Mutation	1	0.11	LCLC97TM1	N	1	0	0	Y
TTBK1	RRVNSPESG	BONE	452	p.E460G	c.1379A>G	Missense_Mutation	1	0.11	HS819T	N	2	0	0	Y
TTBK1	RSGSGSEGS	LARGE_INTESTINE	785	p.S789G	c.2365A>G	Missense_Mutation	1	0.11	RKO	N	1	0	0	N
TTBK1	RVNSPESGR	BONE	453	p.E460G	c.1379A>G	Missense_Mutation	1	0.11	HS819T	Y	6	9	0	N
TTBK1	RVQRVGFSH	ENDOMETRIUM	704	p.R706Q	c.2117G>A	Missense_Mutation	1	0.11	HEC1B	N	1	0	0	N
TTBK1	RVRLLNRVR	STOMACH	698	p.A699V	c.2096C>T	Missense_Mutation	1	0.11	SH10TC	Y	5	9	0	N
TTBK1	RVVNVTPVP	SKIN	339	p.G339R	c.1015G>A	Missense_Mutation	1	0.11	WM88	N	0	0	0	N
TTBK1	SDYRERVRL	STOMACH	693	p.A699V	c.2096C>T	Missense_Mutation	1	0.11	SH10TC	Y	6	10	0	N
TTBK1	SGRLSTADG	BONE	459	p.E460G	c.1379A>G	Missense_Mutation	1	0.11	HS819T	N	0	0	0	N
TTBK1	SGSEGSERS	LARGE_INTESTINE	788	p.S789G	c.2365A>G	Missense_Mutation	1	0.11	RKO	N	1	0	0	N
TTBK1	SGSGSEGSE	LARGE_INTESTINE	786	p.S789G	c.2365A>G	Missense_Mutation	1	0.11	RKO	N	0	0	0	N
TTBK1	SLDYFTKPY	LUNG	277	p.D285Y	c.853G>T	Missense_Mutation	1	0.11	NCIH2110	N	5	0	0	N
TTBK1	SLVTAELAP	SKIN	847	p.P848L	c.2543C>T	Missense_Mutation	1	0.11	WM88	N	0	0	0	N
TTBK1	SPESGRLST	BONE	456	p.E460G	c.1379A>G	Missense_Mutation	1	0.11	HS819T	N	3	0	0	N
TTBK1	SPGDMKKSL	SKIN	840	p.P848L	c.2543C>T	Missense_Mutation	1	0.11	WM88	N	17	0	0	N
TTBK1	SPGDMKKSS	PANCREAS	840	p.P848S	c.2542C>T	Missense_Mutation	1	0.11	PANC0203	N	3	0	0	Y
TTBK1	SPVRAPQDS	SKIN	433	p.P439Q	c.1316C>A	Missense_Mutation	1	0.11	MDAMB435S	N	4	0	0	N
TTBK1	SSPVRAPQD	SKIN	432	p.P439Q	c.1316C>A	Missense_Mutation	1	0.11	MDAMB435S	N	0	0	0	N
TTBK1	SSVTAELAP	PANCREAS	847	p.P848S	c.2542C>T	Missense_Mutation	1	0.11	PANC0203	N	0	0	0	N
TTBK1	STADGLVEL	LUNG	463	p.R468L	c.1403G>T	Missense_Mutation	1	0.11	NCIH1339	Y	10	14	0	N
TTBK1	SVTAELAPD	PANCREAS	848	p.P848S	c.2542C>T	Missense_Mutation	1	0.11	PANC0203	N	0	0	0	N
TTBK1	SVVPPFEVN	LUNG	665	p.A667V	c.2000C>T	Missense_Mutation	1	0.11	LCLC97TM1	N	0	0	0	Y
TTBK1	TAAMFRVVN	SKIN	334	p.G339R	c.1015G>A	Missense_Mutation	1	0.11	WM88	N	1	0	0	N
TTBK1	TADGLVELP	LUNG	464	p.R468L	c.1403G>T	Missense_Mutation	1	0.11	NCIH1339	N	0	0	0	N
TTBK1	TDAFLSTST	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	315	p.L318F	c.952C>T	Missense_Mutation	1	0.11	OCIAML5	N	2	0	0	N
TTBK1	TKPYYQLIM	LUNG	282	p.D285Y	c.853G>T	Missense_Mutation	1	0.11	NCIH2110	N	4	0	0	N
TTBK1	TRQTAAMFR	SKIN	331	p.G339R	c.1015G>A	Missense_Mutation	1	0.11	WM88	N	3	0	0	N
TTBK1	VAGFRGMVR	OVARY	196	p.T202M	c.605C>T	Missense_Mutation	1	0.11	OC316	N	4	0	2	N
TTBK1	VCRFVGCGR	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	90	p.I94V	c.280A>G	Missense_Mutation	1	0.11	JM1	N	3	0	0	N
TTBK1	VFSVVPPFE	LUNG	663	p.A667V	c.2000C>T	Missense_Mutation	1	0.11	LCLC97TM1	N	0	0	0	Y
TTBK1	VGCGRNEKF	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	94	p.I94V	c.280A>G	Missense_Mutation	1	0.11	JM1	N	7	0	0	N
TTBK1	VLGPGSGSS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	781	p.R785G	c.2353C>G	Missense_Mutation	1	0.11	HUT78	N	0	0	0	N
TTBK1	VLGPRSGSG	LARGE_INTESTINE	781	p.S789G	c.2365A>G	Missense_Mutation	1	0.11	RKO	N	0	0	0	Y
TTBK1	VNSPESGRL	BONE	454	p.E460G	c.1379A>G	Missense_Mutation	1	0.11	HS819T	N	5	0	0	Y
TTBK1	VPLAPVQLQ	SKIN	720	p.P727L	c.2180C>T	Missense_Mutation	1	0.11	SKMEL24	N	2	0	11	N
TTBK1	VPPFEVNGL	LUNG	667	p.A667V	c.2000C>T	Missense_Mutation	1	0.11	LCLC97TM1	N	18	0	1	N
TTBK1	VQLQANGKE	SKIN	725	p.P727L	c.2180C>T	Missense_Mutation	1	0.11	SKMEL24	N	0	0	2	N
TTBK1	VQRVGFSHM	ENDOMETRIUM	705	p.R706Q	c.2117G>A	Missense_Mutation	1	0.11	HEC1B	N	8	0	0	N
TTBK1	VRAPQDSPT	SKIN	435	p.P439Q	c.1316C>A	Missense_Mutation	1	0.11	MDAMB435S	N	2	0	0	N
TTBK1	VRLLNRVRR	STOMACH	699	p.A699V	c.2096C>T	Missense_Mutation	1	0.11	SH10TC	Y	3	9	38	N
TTBK1	VVPPFEVNG	LUNG	666	p.A667V	c.2000C>T	Missense_Mutation	1	0.11	LCLC97TM1	Y	0	11	0	Y
TTBK1	WEKADTDAL	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	310	p.G314D	c.941G>A	Missense_Mutation	1	0.11	PF382	Y	11	10	0	N
TTBK1	WEKAGTDAF	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	310	p.L318F	c.952C>T	Missense_Mutation	1	0.11	OCIAML5	Y	9	9	1	N
TTBK1	YFTKPYYQL	LUNG	280	p.D285Y	c.853G>T	Missense_Mutation	1	0.11	NCIH2110	Y	11	11	0	Y
TTBK1	YRERVRLLN	STOMACH	695	p.A699V	c.2096C>T	Missense_Mutation	1	0.11	SH10TC	N	4	0	10	N
TTBK1	YYQLIMSVF	LUNG	285	p.D285Y	c.853G>T	Missense_Mutation	1	0.11	NCIH2110	Y	9	9	0	N