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Page - 1 of 1 HIVsir ID HIV Strain NCBI Accession Target Gene Position of siRNA target Sense Sequence of siRNA Efficacy (%) GC Content (%) Cell line PubMed 1625 Hiv-1 Ptar-gl2(vctr) K02013 LTR N/A UGGCUAACUAGGGAACCCACU 51.00 42 Hela S3 14762201 1186 HIV-1 (LAI) K02013 Tat/Rev 5547 UCCUAUGGCAGGAAGAAGC 51.00 42 293 T 16959541 1404 HIV-1 (LAI) K02013 Gag 331 GAGAGAUGGGUGCGAGAGC 51.00 50 293 T 19384894 1405 HIV-1 (LAI) K02013 Gag 332 AGAGAUGGGUGCGAGAGCG 51.00 50 293 T 19384894 1018 HIV-1 (NL4-3) AF324493 Tat 5979 GAAGCGGAGACAGCGACGA 51.00 50 jurkat 12438622 1423 HIV-1 (NL4-3) AF324493 LTR 63 CAAGGCUACUUCCCUGAUUG 51.20 40 HEK 293a 19497094 1118 HIV-1 (LAI) K02013 Gag 326 AAGGAGAGAGAUGGGUGCG 52.00 46 293 T 16959541 1539 HIV-1 (NL4-3) AF324493 Env 951 AAAUAUCUGUGGAACCUGCUA 52.00 31 U87.CD4.CXCR4 18199654 1518 HIV-1 (NL4-3) AF324493 Nef 351 ACAAGGCUACUUCCCUGAUU 52.20 36 HEK 293a 19497094 1072 HIV-1 (NL4-3) AF324493 LTR 553 AAGUAGUGUGUGCCCGUCUGU 52.20 42 293 T 15750613 1429 HIV-1 (NL4-3) AF324493 LTR 522 GCCUCAAUAAAGCUUGCCUU 52.60 36 HEK 293a 19497094 1419 HIV-1 (LAI) K02013 Tat/Rev 5550 UAUGGCAGGAAGAAGCGGA 53.00 42 293 T 19384894 1138 HIV-1 (LAI) K02013 Pol 1958 UGGAAACCAAAAAUGAUAG 54.00 25 293 T 16959541 1229 HIV-1 HXB2 K03455 LTR 247 AAGUGUUAGAGUGGAGGUUUGAC 54.00 36 HEK 293 17959645 1141 HIV-1 (LAI) K02013 Pol 3756 UUGGAGGAAAUGAACAAGU 54.00 29 293 T 16959541 1195 HIV-1 (LAI) K02013 Nef 8656 CUUUUUAAAAGAAAAGGGG 54.00 25 293 T 16959541 1412 HIV-1 (LAI) K02013 Pol 3755 AUUGGAGGAAAUGAACAAG 54.00 29 19384894 1432 HIV-1 (NL4-3) AF324493 Gag 532 GGAGCCACCCCACAAGAUU U 54.10 42 HEK 293a 19497094 1463 HIV-1 (NL4-3) AF324493 pol 2873 GGAAAGGUGAAGGGGCAGUAG 54.20 46 HEK 293a 19497094 1021 HIV-1 (NL4-3) AF324493 P65 N/A GCCCUAUCCCUUUACGUCA 55.00 42 jurkat 12438622

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