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Page - 1 of 1 HIVsir ID HIV Strain NCBI Accession Target Gene Position of siRNA target Sense Sequence of siRNA Efficacy (%) GC Content (%) Cell line PubMed 1413 HIV-1 (LAI) K02013 Pol 4122 UAGCAGGAAGAUGGCCAGU 57.00 42 293 T 19384894 1073 N/A N/A LTR 553 AAGUAGUGUGUGCCCGUCUGU 57.00 42 293 T 15750613 1536 HIV-1 (LAI) K02013 Tat/Rev 5551 AUGGCAGGAAGAAGCGGAG 57.00 46 vero cells 20188764 1055 HIV-1 (NL4-3) AF324493 Env 7914 AACUCACAGUCUGGGGCAUCA 58.00 42 293 T 15564478 1142 HIV-1 (LAI) K02013 Pol 4121 UUAGCAGGAAGAUGGCCAG 58.00 42 293 T 16959541 1069 HIV-1 (IIIB) EU541617 Nef N/A GCGUCGACGGUAGAAGAGGCCAAUGAA 58.00 47 MT-4 T/Jurkat T 15601474 1507 HIV-1 (NL4-3) AF324493 Env 1432 AGAAGUGAAUUAUAUAAA A 59.50 12 HEK 293a 19497094 1075 N/A N/A Gag 1607 AAUAGUAAGAAUGUAUAGCCC 60.00 27 293 T 15750613 1208 HIV-1 HXB2 K03455 Gag 2930 GUAUAAACAAUGAGACACCAG 60.00 31 Hela 17132935

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