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Page - 1 of 1 HIVsir ID HIV Strain NCBI Accession Target Gene Position of siRNA target Sense Sequence of siRNA Efficacy (%) Target Conservation * Cell line PubMed 1051 HIV-1 (NL4-3) AF324493 Rev N/A GCCTGTGCCTCTTCAGCTACC 38.00 675(45.12%) 293 T 15336659 1100 HIV-1 (NL4-3) AF324493 Rev 8499 GCCUGUGCCUCUUCAGCUACC 100.00 675(45.12%) CEM 16439542 1389 HIV-1 (NL4-3) AF324493 Rev N/A GCACUUAUCUGGGACGAU 78.00 58(3.88%) Hela 18510865 1390 HIV-1 (NL4-3) AF324493 Rev N/A GGUAGCUGAAGAGGCACAGGC 61.00 0(0.00%) Hela 18510865 1391 HIV-1 (NL4-3) AF324493 Rev N/A GAGGGGACCAGGGAGAGCA 63.00 0(0.00%) Hela 18510865 1392 HIV-1 (NL4-3) AF324493 Rev N/A ACUUACUCUUGAUUGUAAC 38.00 117(7.82%) Hela 18510865 1397 HIV-1 (NL4-3) AF324493 Rev 5982 GCGGAGACAGCGACGAAGAGC 82.00 148(9.89%) 293 T 19110017 1515 HIV-1 (NL4-3) AF324493 Rev 158 UGAGAGACUUACUCUUGAUU 97.50 346(23.13%) HEK 293a 19497094 1516 HIV-1 (NL4-3) AF324493 Rev 159 GAGAGACUUACUCUUGAUUG 89.90 336(22.46%) HEK 293a 19497094 1565 HIV-1 (NL4-3) AF324493 rev 8469 GGGCCUGUGCCUCUUCAGCUACCA 90.00 0(0.00%) 293 T 20144240 1579 HIV-1(P89) K02013 rev K*8485 GGCACUUAUCUGGGACGAU 23.00 2(0.13%) Hela 15831707 1576 HIV-1(BAL) K02013 rev K*8485 GGCACUUAUCUGGGACGAU 75.00 2(0.13%) Hela 15831707 1573 HIV-1 (IIIB) EU541617 rev K*8485 GGCACUUAUCUGGGACGAU 96.00 2(0.13%) Hela 15831707 1608 HIV-1 (NL4-3) AF324493 rev K*8509 GCCUGUGCCUCUUCAGCUACC 95.00 675(45.12%) 293 T 18596982 1656 HIV-1 (NL4-3) AF324493 Rev 5545 GAGCUCAUCAGAACAGUCAG 87.00 1(0.07%) 293 FT cells 20949027 1659 HIV-1NL4-3 AF324493 REV 8499 GCCUGUGCCUCUUCAGCUAC 95.00 675(45.12%) Hek 293 17726454

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