Browse Epitopes

This module is created to browse the epitopes predicted from vaccine candidates of all mycobacterial strains. This epitopes were predicted by creating 9mer overlapping peptides from the vaccine candidates from each mycobacterial species. We used a prediction pipeline for predicting the epitopes. Currently, you are browsing B cell epitopes from our compiled results. Here, the first column represent the unique Mtbeveb ID for each peptide sequences. The ID and peptide sequence is hyperlinked to epitope card. The next column contains Gene ID, which is hyperlinked to antigen card. The next column displays the detail of protien from NCBI notation. The fourth column presents the position of the peptide in that protein. This pipeline have the package for predicting linear B cell epitopes using LBtope, promiscous binder of MHC class I (Propred1) and MHC class II (Propred), CTL epitope (CTLpred), interferon-gamma inducing peptides (IFNepitope) and Interleukine 4 inducing peptides (IL4pred). The peptides can sorted at any header. The last five columns present the fields related to MHC class II prediction using Propred followed by prediction of interferon-gamma inducing peptides. The sixth column tells us the MHC class II alleles to which peptide is binding. The seventh column counts the number of MHC class II alleles for that peptide. The eighth column depicts the prediction result of IFNepitope server with ninth column present the alogirithm of IFNepitope program. The last column display the score of peptides from IFNepitope server.


Total number of predicted 9mer peptides are 108182 (corresponding to browse type th1)



ID gene IDProtein DetailPositionSequence (9mer)MHC class II Alleles MHC class II alleles (count) IFN-gamma inducing algorithmIFN-gamma inducing Score
VIR08186031794309 NP 856802.1 twocomponenttranscriptionalregulatoryproteinDevR[MycobacteriumbovisAF2122/97]103VKDIKGMEL DRB1_0701, DRB1_0703, DRB1_1506 3 SVM 0.17
VIR08191431794309 NP 856802.1 twocomponenttranscriptionalregulatoryproteinDevR[MycobacteriumbovisAF2122/97]157LLGLLSEGL DRB1_0101, DRB1_0102, DRB1_0701, DRB1_0703 4 SVM 0.77
VIR08193131794309 NP 856802.1 twocomponenttranscriptionalregulatoryproteinDevR[MycobacteriumbovisAF2122/97]174MFLAEKTVK DRB1_0305, DRB1_0306, DRB1_0307, DRB1_0308, DRB1_0311, DRB1_0813, DRB1_1102, DRB1_1107, DRB1_1121, DRB1_1322, DRB5_0101, DRB5_0105 12 MERCI 0.99
VIR08196431794309 NP 856802.1 twocomponenttranscriptionalregulatoryproteinDevR[MycobacteriumbovisAF2122/97]207LKRSRPPGD DRB1_0301 1 SVM 0.03
VIR08197531794327 NP 856820.1 NADHdehydrogenasesubunitG[MycobacteriumbovisAF2122/97]9IRVGQPEMV DRB1_0101, DRB1_0102, DRB1_0301, DRB1_0305, DRB1_0306, DRB1_0307, DRB1_0308, DRB1_0309, DRB1_0311, DRB1_1107 10 SVM 0.22
VIR08200131794327 NP 856820.1 NADHdehydrogenasesubunitG[MycobacteriumbovisAF2122/97]35IRAAELMGI DRB1_0102, DRB1_0301, DRB1_0305, DRB1_0306, DRB1_0307, DRB1_0308, DRB1_0309, DRB1_0311, DRB1_0701, DRB1_0703, DRB1_0804, DRB1_1101, DRB1_1102, DRB1_1104, DRB1_1106, DRB1_1107, DRB1_1121, DRB1_1128, DRB1_1301, DRB1_1305, DRB1_1307, DRB1_1311, DRB1_1321, DRB1_1322, DRB1_1327, DRB1_1328, DRB1_1501, DRB1_1502, DRB1_1506 29 SVM 0.26
VIR08201131794327 NP 856820.1 NADHdehydrogenasesubunitG[MycobacteriumbovisAF2122/97]45IPRFCDHPL DRB1_1501, DRB1_1506 2 SVM 0.13
VIR08203031794327 NP 856820.1 NADHdehydrogenasesubunitG[MycobacteriumbovisAF2122/97]64LVEVEGQRK DRB5_0101, DRB5_0105 2 SVM 0.52
VIR08203331794327 NP 856820.1 NADHdehydrogenasesubunitG[MycobacteriumbovisAF2122/97]67VEGQRKPLA DRB1_1107 1 SVM 0.41
VIR08205331794327 NP 856820.1 NADHdehydrogenasesubunitG[MycobacteriumbovisAF2122/97]87VRTQLTSEI DRB1_0101, DRB1_0102, DRB1_0301, DRB1_0305, DRB1_0306, DRB1_0307, DRB1_0308, DRB1_0309, DRB1_0311, DRB1_0401, DRB1_0402, DRB1_0404, DRB1_0405, DRB1_0408, DRB1_0410, DRB1_0421, DRB1_0423, DRB1_0426, DRB1_1102, DRB1_1107, DRB1_1114, DRB1_1120, DRB1_1121, DRB1_1301, DRB1_1302, DRB1_1304, DRB1_1322, DRB1_1323, DRB1_1327, DRB1_1328 30 MERCI 0.99
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