Total number of Results for Transgenic mouse model are 15
ASPsiDb_ID Mutant allele/ASP-siRNA Mutant
efficacy (%)
Wild
efficacy (%)
Percentage
discrimination (%)
Gene Disease Analysis Pubmed ID
ASPsiDb_ID Mutant allele/ASP-siRNA Mutant
efficacy (%)
Wild
efficacy (%)
Percentage
discrimination (%)
Gene Disease Analysis Pubmed ID
aspsirna1001 GGAGACUUGCGCAAUGUGA
CCUCUGAACGCGUUACACU
80 20 60 Cu,Zn superoxide dismutase (SOD1) Amyotrophic Lateral Sclerosis (ALS)
12934714
aspsirna0170 UGAAGUGAAUCUGGAUGCAG
ACUUCACUUAGACCUACGUC
60 10 50 Amyloid beta (A4) precursor protein(APP) Alzheimers disease
19532137
aspsirna0342 GACAAAGAUGCUGUGGCCGAU
CUGUUUCUACGACACCGGCUA
74 10 64 Cu,Zn superoxide dismutase (SOD1) Amyotrophic Lateral Sclerosis (ALS)
16857362
aspsirna0804 CGAUUCCAUGUUCAUGAGU
GCUAAGGUACAAGUACUCA
80 74 6 Cu,Zn superoxide dismutase (SOD1) Amyotrophic Lateral Sclerosis (ALS)
15768029
aspsirna0805 UCGAUUCCAUGUUCAUGAG
AGCUAAGGUACAAGUACUC
50 42 8 Cu,Zn superoxide dismutase (SOD1) Amyotrophic Lateral Sclerosis (ALS)
15768029
aspsirna1000 UGGAGACUUGCGCAAUGUG
ACCUCUGAACGCGUUACAC
95 10 85 Cu,Zn superoxide dismutase (SOD1) Amyotrophic Lateral Sclerosis (ALS)
12934714
aspsirna1002 GAGACUUGCGCAAUGUGAC
CUCUGAACGCGUUACACUG
96 23 73 Cu,Zn superoxide dismutase (SOD1) Amyotrophic Lateral Sclerosis (ALS)
12934714
aspsirna1003 UGGAGACUUGGGCAAUGUG
ACCUCUGAACCCGUUACAC
82 5 77 Cu,Zn superoxide dismutase (SOD1) Amyotrophic Lateral Sclerosis (ALS)
12934714
aspsirna1004 GGAGACUUGGGCAAUGUGA
CCUCUGAACCCGUUACACU
20 46 -26 Cu,Zn superoxide dismutase (SOD1) Amyotrophic Lateral Sclerosis (ALS)
12934714
aspsirna1005 GAGACUUGGGCAAUGUGAC
CUCUGAACCCGUUACACUG
NA NA NA Cu,Zn superoxide dismutase (SOD1) Amyotrophic Lateral Sclerosis (ALS)
12934714
aspsirna3121 GAUCAAGACCCUCAAAAAC
CUAGUUCUGGGAGUUUUUG
56 42 14 Keratin 6a (KRT6a) Pachyonychia congenita (PC)
19935778
aspsirna3122 CCCUCAAAAACAAGUUUGC
GGGAGUUUUUGUUCAAACG
35 0 35 Keratin 6a (KRT6a) Pachyonychia congenita (PC)
19935778
aspsirna3178 UUGCCAGGUUGCAGCUGCUCUU
AACGGUCCAACGUCGACGAGAA
90 26 64 Hungtintin (HTT) Huntington disease (HD)
25849618
aspsirna3258 GGCCUCUUGGCUCUUGGAU
CCGGAGAACCGAGAACCUA
80 2 78 keratin 9 (KRT9) Epidermolytic palmoplantar keratoderma (EPPK)
27003758
aspsirna3259 GGCCUCUUGGCUCUUGGAU
CCGGAGAACCGAGAACCUA
73 10 63 keratin 9 (KRT9) Epidermolytic palmoplantar keratoderma (EPPK)
27003758