ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna0705 | AGGCAUGUUGGAGACUUGC UCCGUACAACCUCUGAACG |
88 | 78 | 10 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0706 | GGCAUGUUGGAGACUUGCG CCGUACAACCUCUGAACGC |
88 | 55 | 33 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0707 | GCAUGUUGGAGACUUGCGC CGUACAACCUCUGAACGCG |
92 | 25 | 67 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0708 | CAUGUUGGAGACUUGCGCA GUACAACCUCUGAACGCGU |
94 | 40 | 54 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0709 | AUGUUGGAGACUUGCGCAA UACAACCUCUGAACGCGUU |
95 | 40 | 55 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0710 | UGUUGGAGACUUGCGCAAU ACAACCUCUGAACGCGUUA |
90 | 35 | 55 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0711 | GUUGGAGACUUGCGCAAUG CAACCUCUGAACGCGUUAC |
94 | 60 | 34 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0712 | UUGGAGACUUGCGCAAUGU AACCUCUGAACGCGUUACA |
81 | 32 | 49 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0713 | UGGAGACUUGCGCAAUGUG ACCUCUGAACGCGUUACAC |
84 | 46 | 38 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0714 | GGAGACUUGCGCAAUGUGA CCUCUGAACGCGUUACACU |
90 | 32 | 58 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0715 | GAGACUUGCGCAAUGUGAC CUCUGAACGCGUUACACUG |
76 | 25 | 51 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0716 | AGACUUGCGCAAUGUGACU UCUGAACGCGUUACACUGA |
85 | 32 | 53 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0717 | GACUUGCGCAAUGUGACUG CUGAACGCGUUACACUGAC |
62 | 28 | 34 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0718 | ACUUGCGCAAUGUGACUGC UGAACGCGUUACACUGACG |
72 | 55 | 17 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0719 | CUUGCGCAAUGUGACUGCU GAACGCGUUACACUGACGA |
80 | 75 | 5 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0720 | UUGCGCAAUGUGACUGCUG AACGCGUUACACUGACGAC |
77 | 32 | 45 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0721 | UGCGCAAUGUGACUGCUGA ACGCGUUACACUGACGACU |
84 | 80 | 4 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0722 | GCGCAAUGUGACUGCUGAC CGCGUUACACUGACGACUG |
70 | 68 | 2 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0723 | CGCAAUGUGACUGCUGACA GCGUUACACUGACGACUGU |
83 | 82 | 1 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0724 | GAGACUUGCGCAAUGUGAC CUCUGAACGCGUUACACUG |
88 | 85 | 3 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna2248 | AGGCAUGUUGGAGACUUGC UCCGUACAACCUCUGAACG |
90 | 85 | 5 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ||
aspsirna2249 | GGCAUGUUGGAGACUUGCG CCGUACAACCUCUGAACGC |
90 | 70 | 20 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ||
aspsirna2250 | GCAUGUUGGAGACUUGCGC CGUACAACCUCUGAACGCG |
90 | 45 | 45 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ||
aspsirna2251 | CAUGUUGGAGACUUGCGCA GUACAACCUCUGAACGCGU |
90 | 50 | 40 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ||
aspsirna2252 | AUGUUGGAGACUUGCGCAA UACAACCUCUGAACGCGUU |
90 | 15 | 75 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ||
aspsirna2253 | UGUUGGAGACUUGCGCAAU ACAACCUCUGAACGCGUUA |
90 | 70 | 20 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ||
aspsirna2254 | GUUGGAGACUUGCGCAAUG CAACCUCUGAACGCGUUAC |
90 | 50 | 40 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ||
aspsirna2255 | UUGGAGACUUGCGCAAUGU AACCUCUGAACGCGUUACA |
95 | 75 | 20 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ||
aspsirna2256 | UGGAGACUUGCGCAAUGUG ACCUCUGAACGCGUUACAC |
90 | 10 | 80 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ||
aspsirna2257 | GGAGACUUGCGCAAUGUGA CCUCUGAACGCGUUACACU |
88 | 10 | 78 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ||
aspsirna2258 | GAGACUUGCGCAAUGUGAC CUCUGAACGCGUUACACUG |
85 | 35 | 50 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ||
aspsirna2259 | AGACUUGCGCAAUGUGACU UCUGAACGCGUUACACUGA |
40 | 10 | 30 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ||
aspsirna2260 | GACUUGCGCAAUGUGACUG CUGAACGCGUUACACUGAC |
90 | 15 | 75 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ||
aspsirna2261 | ACUUGCGCAAUGUGACUGC UGAACGCGUUACACUGACG |
88 | 10 | 78 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ||
aspsirna2262 | CUUGCGCAAUGUGACUGCU GAACGCGUUACACUGACGA |
70 | 30 | 40 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ||
aspsirna2263 | UUGCGCAAUGUGACUGCUG AACGCGUUACACUGACGAC |
80 | 20 | 60 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ||
aspsirna2264 | UGCGCAAUGUGACUGCUGA ACGCGUUACACUGACGACU |
90 | 30 | 60 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ||
aspsirna2265 | GCGCAAUGUGACUGCUGAC CGCGUUACACUGACGACUG |
85 | 40 | 45 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ||
aspsirna2266 | CGCAAUGUGACUGCUGACA GCGUUACACUGACGACUGU |
40 | 10 | 30 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ||
aspsirna2267 | GAGACUUGCGCAAUGUGAC CUCUGAACGCGUUACACUG |
50 | 5 | 45 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ||
aspsirna2268 | AUGUUGGAGACUUGCGCAA UACAACCUCUGAACGCGUU |
90 | 30 | 60 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ||
aspsirna2269 | UGGAGACUUGCGCAAUGUG ACCUCUGAACGCGUUACAC |
85 | 40 | 45 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ||
aspsirna2270 | GGAGACUUGCGCAAUGUGA CCUCUGAACGCGUUACACU |
80 | 20 | 60 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ||
aspsirna2271 | AGACUUGCGCAAUGUGACU UCUGAACGCGUUACACUGA |
50 | 5 | 45 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ||
aspsirna2272 | GACUUGCGCAAUGUGACUG CUGAACGCGUUACACUGAC |
90 | 25 | 65 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ||
aspsirna2273 | ACUUGCGCAAUGUGACUGC UGAACGCGUUACACUGACG |
88 | 18 | 70 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ||
aspsirna2274 | CUUGCGCAAUGUGACUGCU GAACGCGUUACACUGACGA |
70 | 40 | 30 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ||
aspsirna2275 | UUGCGCAAUGUGACUGCUG AACGCGUUACACUGACGAC |
80 | 8 | 72 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ||
aspsirna2276 | CGCAAUGUGACUGCUGACA GCGUUACACUGACGACUGU |
55 | 50 | 5 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |