ASPsiRNA | Allele specific siRNA Resource

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ASPsiRNA ID	Pairing of target region (top) and ASP-siRNA (bottom)	Efficacy (mut)(%)	Efficacy (wt) (%)	Diff	Gene	Disease	Mutation	RefSNP	Pubmed ID

aspsirna0089	GUGCACAACUGCGUCAAUA CACGUGUUGACGCAGUUAU	82	95	-13	PRNP	Prion disease/Creutzfeldt-Jakob disease	c.532G>A,p.Asp178Asn	rs74315403	18493311
aspsirna0090	UGUGCACAACUGCGUCAAU ACACGUGUUGACGCAGUUA	88	70	18	PRNP	Prion disease/Creutzfeldt-Jakob disease	c.532G>A,p.Asp178Asn	rs74315403	18493311
aspsirna0091	UUUGUGCACAACUGCGUCA AAACACGUGUUGACGCAGU	65	90	-25	PRNP	Prion disease/Creutzfeldt-Jakob disease	c.532G>A,p.Asp178Asn	rs74315403	18493311
aspsirna0092	CUUUGUGCACAACUGCGUC GAAACACGUGUUGACGCAG	75	92	-17	PRNP	Prion disease/Creutzfeldt-Jakob disease	c.532G>A,p.Asp178Asn	rs74315403	18493311
aspsirna0093	ACUUUGUGCACAACUGCGU UGAAACACGUGUUGACGCA	82	93	-11	PRNP	Prion disease/Creutzfeldt-Jakob disease	c.532G>A,p.Asp178Asn	rs74315403	18493311
aspsirna0124	UUGUGCACAACUGCGUCAA AACACGUGUUGACGCAGUU	70	89	-19	PRNP	Prion disease/Creutzfeldt-Jakob disease	c.532G>A,p.Asp178Asn	rs74315403	18493311
aspsirna0125	UUGUCCACAACUGCGUCAA AACAGGUGUUGACGCAGUU	90	88	2	PRNP	Prion disease/Creutzfeldt-Jakob disease	c.532G>A,p.Asp178Asn	rs74315403	18493311
aspsirna0126	UUGUGGACAACUGCGUCAA AACACCUGUUGACGCAGUU	52	88	-36	PRNP	Prion disease/Creutzfeldt-Jakob disease	c.532G>A,p.Asp178Asn	rs74315403	18493311
aspsirna0127	UUGUGCACAACAGCGUCAA AACACGUGUUGUCGCAGUU	70	88	-18	PRNP	Prion disease/Creutzfeldt-Jakob disease	c.532G>A,p.Asp178Asn	rs74315403	18493311
aspsirna0128	UUGUGCACAACUCCGUCAA AACACGUGUUGAGGCAGUU	22	88	-66	PRNP	Prion disease/Creutzfeldt-Jakob disease	c.532G>A,p.Asp178Asn	rs74315403	18493311
aspsirna0129	UUGUGCACAACUGGGUCAA AACACGUGUUGACCCAGUU	78	88	-10	PRNP	Prion disease/Creutzfeldt-Jakob disease	c.532G>A,p.Asp178Asn	rs74315403	18493311
aspsirna0130	UUGUGCACAACUGCCUCAA AACACGUGUUGACGGAGUU	60	88	-28	PRNP	Prion disease/Creutzfeldt-Jakob disease	c.532G>A,p.Asp178Asn	rs74315403	18493311
aspsirna0131	UUGUGCACAACUGCGACAA AACACGUGUUGACGCUGUU	90	88	2	PRNP	Prion disease/Creutzfeldt-Jakob disease	c.532G>A,p.Asp178Asn	rs74315403	18493311
aspsirna0132	UUGUGCACAACUGCGUGAA AACACGUGUUGACGCACUU	12	88	-76	PRNP	Prion disease/Creutzfeldt-Jakob disease	c.532G>A,p.Asp178Asn	rs74315403	18493311
aspsirna0160	UUGUGCACAACUGCGUCAA AACACGUGUUGACGCAGUU	70	89	-19	PRNP	Prion disease/Creutzfeldt-Jakob disease	c.532G>A,p.Asp178Asn	rs74315403	18493311
aspsirna0161	UUGUCCACAACUGCGUCAA AACAGGUGUUGACGCAGUU	90	88	2	PRNP	Prion disease/Creutzfeldt-Jakob disease	c.532G>A,p.Asp178Asn	rs74315403	18493311
aspsirna0162	UUGUGGACAACUGCGUCAA AACACCUGUUGACGCAGUU	52	88	-36	PRNP	Prion disease/Creutzfeldt-Jakob disease	c.532G>A,p.Asp178Asn	rs74315403	18493311
aspsirna0163	UUGUGCACAACAGCGUCAA AACACGUGUUGUCGCAGUU	70	88	-18	PRNP	Prion disease/Creutzfeldt-Jakob disease	c.532G>A,p.Asp178Asn	rs74315403	18493311
aspsirna0164	UUGUGCACAACUCCGUCAA AACACGUGUUGAGGCAGUU	22	88	-66	PRNP	Prion disease/Creutzfeldt-Jakob disease	c.532G>A,p.Asp178Asn	rs74315403	18493311
aspsirna0165	UUGUGCACAACUGGGUCAA AACACGUGUUGACCCAGUU	78	88	-10	PRNP	Prion disease/Creutzfeldt-Jakob disease	c.532G>A,p.Asp178Asn	rs74315403	18493311
aspsirna0166	UUGUGCACAACUGCCUCAA AACACGUGUUGACGGAGUU	60	88	-28	PRNP	Prion disease/Creutzfeldt-Jakob disease	c.532G>A,p.Asp178Asn	rs74315403	18493311
aspsirna0167	UUGUGCACAACUGCGACAA AACACGUGUUGACGCUGUU	90	88	2	PRNP	Prion disease/Creutzfeldt-Jakob disease	c.532G>A,p.Asp178Asn	rs74315403	18493311
aspsirna0168	UUGUGCACAACUGCGUGAA AACACGUGUUGACGCACUU	12	88	-76	PRNP	Prion disease/Creutzfeldt-Jakob disease	c.532G>A,p.Asp178Asn	rs74315403	18493311
aspsirna3504	GUGCACAACUGCGUCAAUA CACGUGUUGACGCAGUUAU	82	95	-13	PRNP	Prion disease/Creutzfeldt-Jakob disease	c.532G>A,p.Asp178Asn	rs74315403	18493311
aspsirna3505	UGUGCACAACUGCGUCAAU ACACGUGUUGACGCAGUUA	88	70	18	PRNP	Prion disease/Creutzfeldt-Jakob disease	c.532G>A,p.Asp178Asn	rs74315403	18493311
aspsirna3506	UUUGUGCACAACUGCGUCA AAACACGUGUUGACGCAGU	65	90	-25	PRNP	Prion disease/Creutzfeldt-Jakob disease	c.532G>A,p.Asp178Asn	rs74315403	18493311
aspsirna3507	CUUUGUGCACAACUGCGUC GAAACACGUGUUGACGCAG	75	92	-17	PRNP	Prion disease/Creutzfeldt-Jakob disease	c.532G>A,p.Asp178Asn	rs74315403	18493311
aspsirna3508	ACUUUGUGCACAACUGCGU UGAAACACGUGUUGACGCA	82	93	-11	PRNP	Prion disease/Creutzfeldt-Jakob disease	c.532G>A,p.Asp178Asn	rs74315403	18493311

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