ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna0089 | GUGCACAACUGCGUCAAUA CACGUGUUGACGCAGUUAU |
82 | 95 | -13 | PRNP | Prion disease/Creutzfeldt-Jakob disease | c.532G>A,p.Asp178Asn | rs74315403 | ||
aspsirna0090 | UGUGCACAACUGCGUCAAU ACACGUGUUGACGCAGUUA |
88 | 70 | 18 | PRNP | Prion disease/Creutzfeldt-Jakob disease | c.532G>A,p.Asp178Asn | rs74315403 | ||
aspsirna0091 | UUUGUGCACAACUGCGUCA AAACACGUGUUGACGCAGU |
65 | 90 | -25 | PRNP | Prion disease/Creutzfeldt-Jakob disease | c.532G>A,p.Asp178Asn | rs74315403 | ||
aspsirna0092 | CUUUGUGCACAACUGCGUC GAAACACGUGUUGACGCAG |
75 | 92 | -17 | PRNP | Prion disease/Creutzfeldt-Jakob disease | c.532G>A,p.Asp178Asn | rs74315403 | ||
aspsirna0093 | ACUUUGUGCACAACUGCGU UGAAACACGUGUUGACGCA |
82 | 93 | -11 | PRNP | Prion disease/Creutzfeldt-Jakob disease | c.532G>A,p.Asp178Asn | rs74315403 | ||
aspsirna0124 | UUGUGCACAACUGCGUCAA AACACGUGUUGACGCAGUU |
70 | 89 | -19 | PRNP | Prion disease/Creutzfeldt-Jakob disease | c.532G>A,p.Asp178Asn | rs74315403 | ||
aspsirna0125 | UUGUCCACAACUGCGUCAA AACAGGUGUUGACGCAGUU |
90 | 88 | 2 | PRNP | Prion disease/Creutzfeldt-Jakob disease | c.532G>A,p.Asp178Asn | rs74315403 | ||
aspsirna0126 | UUGUGGACAACUGCGUCAA AACACCUGUUGACGCAGUU |
52 | 88 | -36 | PRNP | Prion disease/Creutzfeldt-Jakob disease | c.532G>A,p.Asp178Asn | rs74315403 | ||
aspsirna0127 | UUGUGCACAACAGCGUCAA AACACGUGUUGUCGCAGUU |
70 | 88 | -18 | PRNP | Prion disease/Creutzfeldt-Jakob disease | c.532G>A,p.Asp178Asn | rs74315403 | ||
aspsirna0128 | UUGUGCACAACUCCGUCAA AACACGUGUUGAGGCAGUU |
22 | 88 | -66 | PRNP | Prion disease/Creutzfeldt-Jakob disease | c.532G>A,p.Asp178Asn | rs74315403 | ||
aspsirna0129 | UUGUGCACAACUGGGUCAA AACACGUGUUGACCCAGUU |
78 | 88 | -10 | PRNP | Prion disease/Creutzfeldt-Jakob disease | c.532G>A,p.Asp178Asn | rs74315403 | ||
aspsirna0130 | UUGUGCACAACUGCCUCAA AACACGUGUUGACGGAGUU |
60 | 88 | -28 | PRNP | Prion disease/Creutzfeldt-Jakob disease | c.532G>A,p.Asp178Asn | rs74315403 | ||
aspsirna0131 | UUGUGCACAACUGCGACAA AACACGUGUUGACGCUGUU |
90 | 88 | 2 | PRNP | Prion disease/Creutzfeldt-Jakob disease | c.532G>A,p.Asp178Asn | rs74315403 | ||
aspsirna0132 | UUGUGCACAACUGCGUGAA AACACGUGUUGACGCACUU |
12 | 88 | -76 | PRNP | Prion disease/Creutzfeldt-Jakob disease | c.532G>A,p.Asp178Asn | rs74315403 | ||
aspsirna0160 | UUGUGCACAACUGCGUCAA AACACGUGUUGACGCAGUU |
70 | 89 | -19 | PRNP | Prion disease/Creutzfeldt-Jakob disease | c.532G>A,p.Asp178Asn | rs74315403 | ||
aspsirna0161 | UUGUCCACAACUGCGUCAA AACAGGUGUUGACGCAGUU |
90 | 88 | 2 | PRNP | Prion disease/Creutzfeldt-Jakob disease | c.532G>A,p.Asp178Asn | rs74315403 | ||
aspsirna0162 | UUGUGGACAACUGCGUCAA AACACCUGUUGACGCAGUU |
52 | 88 | -36 | PRNP | Prion disease/Creutzfeldt-Jakob disease | c.532G>A,p.Asp178Asn | rs74315403 | ||
aspsirna0163 | UUGUGCACAACAGCGUCAA AACACGUGUUGUCGCAGUU |
70 | 88 | -18 | PRNP | Prion disease/Creutzfeldt-Jakob disease | c.532G>A,p.Asp178Asn | rs74315403 | ||
aspsirna0164 | UUGUGCACAACUCCGUCAA AACACGUGUUGAGGCAGUU |
22 | 88 | -66 | PRNP | Prion disease/Creutzfeldt-Jakob disease | c.532G>A,p.Asp178Asn | rs74315403 | ||
aspsirna0165 | UUGUGCACAACUGGGUCAA AACACGUGUUGACCCAGUU |
78 | 88 | -10 | PRNP | Prion disease/Creutzfeldt-Jakob disease | c.532G>A,p.Asp178Asn | rs74315403 | ||
aspsirna0166 | UUGUGCACAACUGCCUCAA AACACGUGUUGACGGAGUU |
60 | 88 | -28 | PRNP | Prion disease/Creutzfeldt-Jakob disease | c.532G>A,p.Asp178Asn | rs74315403 | ||
aspsirna0167 | UUGUGCACAACUGCGACAA AACACGUGUUGACGCUGUU |
90 | 88 | 2 | PRNP | Prion disease/Creutzfeldt-Jakob disease | c.532G>A,p.Asp178Asn | rs74315403 | ||
aspsirna0168 | UUGUGCACAACUGCGUGAA AACACGUGUUGACGCACUU |
12 | 88 | -76 | PRNP | Prion disease/Creutzfeldt-Jakob disease | c.532G>A,p.Asp178Asn | rs74315403 | ||
aspsirna3504 | GUGCACAACUGCGUCAAUA CACGUGUUGACGCAGUUAU |
82 | 95 | -13 | PRNP | Prion disease/Creutzfeldt-Jakob disease | c.532G>A,p.Asp178Asn | rs74315403 | ||
aspsirna3505 | UGUGCACAACUGCGUCAAU ACACGUGUUGACGCAGUUA |
88 | 70 | 18 | PRNP | Prion disease/Creutzfeldt-Jakob disease | c.532G>A,p.Asp178Asn | rs74315403 | ||
aspsirna3506 | UUUGUGCACAACUGCGUCA AAACACGUGUUGACGCAGU |
65 | 90 | -25 | PRNP | Prion disease/Creutzfeldt-Jakob disease | c.532G>A,p.Asp178Asn | rs74315403 | ||
aspsirna3507 | CUUUGUGCACAACUGCGUC GAAACACGUGUUGACGCAG |
75 | 92 | -17 | PRNP | Prion disease/Creutzfeldt-Jakob disease | c.532G>A,p.Asp178Asn | rs74315403 | ||
aspsirna3508 | ACUUUGUGCACAACUGCGU UGAAACACGUGUUGACGCA |
82 | 93 | -11 | PRNP | Prion disease/Creutzfeldt-Jakob disease | c.532G>A,p.Asp178Asn | rs74315403 |