Total number of Results for Prion disease/Gerstmann-Straussler disease are 75
ASPsiRNA ID Pairing of target region (top) and ASP-siRNA (bottom) Efficacy (mut)(%) Efficacy (wt) (%) Diff Gene Disease Mutation RefSNP Analysis Pubmed ID
ASPsiRNA ID Mutant allele/ASP-siRNA Efficacy
for mutant(%)
Efficacy
for wild (%)
Relative Difference (%) Gene Disease Mutation RefSNP Analysis Pubmed ID
aspsirna0080 ACAAGCUGAGUAAGCCAAA
UGUUCGACUCAUUCGGUUU
55 95 -40 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0081 AACAAGCUGAGUAAGCCAA
UUGUUCGACUCAUUCGGUU
38 90 -52 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0082 UGGAACAAGCUGAGUAAGC
ACCUUGUUCGACUCAUUCG
20 -23 43 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0083 GUGGAACAAGCUGAGUAAG
CACCUUGUUCGACUCAUUC
52 82 -30 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0084 GUAAGCUAAAAACCAACAU
CAUUCGAUUUUUGGUUGUA
57 88 -31 PRNP Prion disease/Gerstmann-Straussler disease c.314C>T,p.Pro105Leu rs11538758
18493311
aspsirna0085 AGUAAGCUAAAAACCAACA
UCAUUCGAUUUUUGGUUGU
60 63 -3 PRNP Prion disease/Gerstmann-Straussler disease c.314C>T,p.Pro105Leu rs11538758
18493311
aspsirna0086 GAGUAAGCUAAAAACCAAC
CUCAUUCGAUUUUUGGUUG
27 96 -69 PRNP Prion disease/Gerstmann-Straussler disease c.314C>T,p.Pro105Leu rs11538758
18493311
aspsirna0087 CCGAGUAAGCUAAAAACCA
GGCUCAUUCGAUUUUUGGU
84 92 -8 PRNP Prion disease/Gerstmann-Straussler disease c.314C>T,p.Pro105Leu rs11538758
18493311
aspsirna0088 GCCGAGUAAGCUAAAAACC
CGGCUCAUUCGAUUUUUGG
74 87 -13 PRNP Prion disease/Gerstmann-Straussler disease c.314C>T,p.Pro105Leu rs11538758
18493311
aspsirna0094 GAACAAGCUGAGUAAGCCA
CUUGUUCGACUCAUUCGGU
90 99 -9 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0095 GAACUAGCUGAGUAAGCCA
CUUGAUCGACUCAUUCGGU
98 90 8 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0096 GAACAUGCUGAGUAAGCCA
CUUGUACGACUCAUUCGGU
85 98 -13 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0097 GAACAACCUGAGUAAGCCA
CUUGUUGGACUCAUUCGGU
86 98 -12 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0098 GAACAAGCUGACUAAGCCA
CUUGUUCGACUGAUUCGGU
92 98 -6 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0099 GAACAAGCUGAGAAAGCCA
CUUGUUCGACUCUUUCGGU
99 80 19 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0100 GAACAAGCUGAGUUAGCCA
CUUGUUCGACUCAAUCGGU
96 98 -2 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0101 GAACAAGCUGAGUAUGCCA
CUUGUUCGACUCAUACGGU
97 98 -1 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0102 GAACAAGCUGAGUAACCCA
CUUGUUCGACUCAUUGGGU
87 98 -11 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0103 GAACAAGCUGAGUAAGGCA
CUUGUUCGACUCAUUCCGU
95 98 -3 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0104 CGAGUAAGCUAAAAACCAA
GCUCAUUCGAUUUUUGGUU
86 98 -12 PRNP Prion disease/Gerstmann-Straussler disease c.314C>T,p.Pro105Leu rs11538758
18493311
aspsirna0105 CGAGAAAGCUAAAAACCAA
GCUCUUUCGAUUUUUGGUU
87 99 -12 PRNP Prion disease/Gerstmann-Straussler disease c.314C>T,p.Pro105Leu rs11538758
18493311
aspsirna0106 CGAGUUAGCUAAAAACCAA
GCUCAAUCGAUUUUUGGUU
84 99 -15 PRNP Prion disease/Gerstmann-Straussler disease c.314C>T,p.Pro105Leu rs11538758
18493311
aspsirna0107 CGAGUAACCUAAAAACCAA
GCUCAUUGGAUUUUUGGUU
79 99 -20 PRNP Prion disease/Gerstmann-Straussler disease c.314C>T,p.Pro105Leu rs11538758
18493311
aspsirna0108 CGAGUAAGCUAUAAACCAA
GCUCAUUCGAUAUUUGGUU
67 99 -32 PRNP Prion disease/Gerstmann-Straussler disease c.314C>T,p.Pro105Leu rs11538758
18493311
aspsirna0109 CGAGUAAGCUAAUAACCAA
GCUCAUUCGAUUAUUGGUU
20 99 -79 PRNP Prion disease/Gerstmann-Straussler disease c.314C>T,p.Pro105Leu rs11538758
18493311
aspsirna0110 CGAGUAAGCUAAAUACCAA
GCUCAUUCGAUUUAUGGUU
82 99 -17 PRNP Prion disease/Gerstmann-Straussler disease c.314C>T,p.Pro105Leu rs11538758
18493311
aspsirna0111 CGAGUAAGCUAAAAUCCAA
GCUCAUUCGAUUUUAGGUU
36 99 -63 PRNP Prion disease/Gerstmann-Straussler disease c.314C>T,p.Pro105Leu rs11538758
18493311
aspsirna0112 CGAGUAAGCUAAAAAGCAA
GCUCAUUCGAUUUUUCGUU
39 99 -60 PRNP Prion disease/Gerstmann-Straussler disease c.314C>T,p.Pro105Leu rs11538758
18493311
aspsirna0113 CGAGUAAGCUAAAAACGAA
GCUCAUUCGAUUUUUGCUU
0 99 -99 PRNP Prion disease/Gerstmann-Straussler disease c.314C>T,p.Pro105Leu rs11538758
18493311
aspsirna0114 GGAACAAGCUGAGUAAGCC
CCUUGUUCGACUCAUUCGG
85 90 -5 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0115 GGAAGAAGCUGAGUAAGCC
CCUUCUUCGACUCAUUCGG
38 90 -52 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0116 GGAACUAGCUGAGUAAGCC
CCUUGAUCGACUCAUUCGG
0 90 -90 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0117 GGAACAACCUGAGUAAGCC
CCUUGUUGGACUCAUUCGG
0 90 -90 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0118 GGAACAAGCUGUGUAAGCC
CCUUGUUCGACACAUUCGG
70 90 -20 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0119 GGAACAAGCUGACUAAGCC
CCUUGUUCGACUGAUUCGG
30 90 -60 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0120 GGAACAAGCUGAGAAAGCC
CCUUGUUCGACUCUUUCGG
94 90 4 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0121 GGAACAAGCUGAGUUAGCC
CCUUGUUCGACUCAAUCGG
50 90 -40 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0122 GGAACAAGCUGAGUAUGCC
CCUUGUUCGACUCAUACGG
90 90 0 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0123 GGAACAAGCUGAGUAACCC
CCUUGUUCGACUCAUUGGG
55 90 -35 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0133 GAACAAGCUGAGUAAGCCA
CUUGUUCGACUCAUUCGGU
90 99 -9 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0134 GAACUAGCUGAGUAAGCCA
CUUGAUCGACUCAUUCGGU
98 90 8 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0135 GAACAUGCUGAGUAAGCCA
CUUGUACGACUCAUUCGGU
85 98 -13 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0136 GAACAACCUGAGUAAGCCA
CUUGUUGGACUCAUUCGGU
86 98 -12 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0137 GAACAAGCUGACUAAGCCA
CUUGUUCGACUGAUUCGGU
92 98 -6 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0138 GAACAAGCUGAGAAAGCCA
CUUGUUCGACUCUUUCGGU
99 80 19 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0139 GAACAAGCUGAGUUAGCCA
CUUGUUCGACUCAAUCGGU
96 98 -2 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0140 GAACAAGCUGAGUAUGCCA
CUUGUUCGACUCAUACGGU
97 98 -1 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0141 GAACAAGCUGAGUAACCCA
CUUGUUCGACUCAUUGGGU
87 98 -11 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0142 GAACAAGCUGAGUAAGGCA
CUUGUUCGACUCAUUCCGU
95 98 -3 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0143 CGAGUAAGCUAAAAACCAA
GCUCAUUCGAUUUUUGGUU
86 98 -12 PRNP Prion disease/Gerstmann-Straussler disease c.314C>T,p.Pro105Leu rs11538758
18493311
aspsirna0144 CGAGAAAGCUAAAAACCAA
GCUCUUUCGAUUUUUGGUU
87 99 -12 PRNP Prion disease/Gerstmann-Straussler disease c.314C>T,p.Pro105Leu rs11538758
18493311
aspsirna0145 CGAGUUAGCUAAAAACCAA
GCUCAAUCGAUUUUUGGUU
84 99 -15 PRNP Prion disease/Gerstmann-Straussler disease c.314C>T,p.Pro105Leu rs11538758
18493311
aspsirna0146 CGAGUAACCUAAAAACCAA
GCUCAUUGGAUUUUUGGUU
79 99 -20 PRNP Prion disease/Gerstmann-Straussler disease c.314C>T,p.Pro105Leu rs11538758
18493311
aspsirna0147 CGAGUAAGCUAUAAACCAA
GCUCAUUCGAUAUUUGGUU
67 99 -32 PRNP Prion disease/Gerstmann-Straussler disease c.314C>T,p.Pro105Leu rs11538758
18493311
aspsirna0148 CGAGUAAGCUAAUAACCAA
GCUCAUUCGAUUAUUGGUU
20 99 -79 PRNP Prion disease/Gerstmann-Straussler disease c.314C>T,p.Pro105Leu rs11538758
18493311
aspsirna0149 CGAGUAAGCUAAAUACCAA
GCUCAUUCGAUUUAUGGUU
82 99 -17 PRNP Prion disease/Gerstmann-Straussler disease c.314C>T,p.Pro105Leu rs11538758
18493311
aspsirna0150 CGAGUAAGCUAAAAUCCAA
GCUCAUUCGAUUUUAGGUU
36 99 -63 PRNP Prion disease/Gerstmann-Straussler disease c.314C>T,p.Pro105Leu rs11538758
18493311
aspsirna0151 CGAGUAAGCUAAAAAGCAA
GCUCAUUCGAUUUUUCGUU
39 99 -60 PRNP Prion disease/Gerstmann-Straussler disease c.314C>T,p.Pro105Leu rs11538758
18493311
aspsirna0152 CGAGUAAGCUAAAAACGAA
GCUCAUUCGAUUUUUGCUU
0 99 -99 PRNP Prion disease/Gerstmann-Straussler disease c.314C>T,p.Pro105Leu rs11538758
18493311
aspsirna0153 GGAACAACCUGAGUAAGCC
CCUUGUUGGACUCAUUCGG
0 90 -90 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0154 GGAACAAGCUGUGUAAGCC
CCUUGUUCGACACAUUCGG
70 90 -20 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0155 GGAACAAGCUGACUAAGCC
CCUUGUUCGACUGAUUCGG
30 90 -60 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0156 GGAACAAGCUGAGAAAGCC
CCUUGUUCGACUCUUUCGG
94 90 4 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0157 GGAACAAGCUGAGUUAGCC
CCUUGUUCGACUCAAUCGG
50 90 -40 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0158 GGAACAAGCUGAGUAUGCC
CCUUGUUCGACUCAUACGG
90 90 0 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna0159 GGAACAAGCUGAGUAACCC
CCUUGUUCGACUCAUUGGG
55 90 -35 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna3495 ACAAGCUGAGUAAGCCAAA
UGUUCGACUCAUUCGGUUU
60 100 -40 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna3496 AACAAGCUGAGUAAGCCAA
UUGUUCGACUCAUUCGGUU
40 90 -50 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna3497 UGGAACAAGCUGAGUAAGC
ACCUUGUUCGACUCAUUCG
30 -23 53 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna3498 GUGGAACAAGCUGAGUAAG
CACCUUGUUCGACUCAUUC
60 82 -22 PRNP Prion disease/Gerstmann-Straussler disease c.305C>T,p.Pro102Leu rs74315401
18493311
aspsirna3499 GUAAGCUAAAAACCAACAU
CAUUCGAUUUUUGGUUGUA
60 88 -28 PRNP Prion disease/Gerstmann-Straussler disease c.314C>T,p.Pro105Leu rs11538758
18493311
aspsirna3500 AGUAAGCUAAAAACCAACA
UCAUUCGAUUUUUGGUUGU
60 63 -3 PRNP Prion disease/Gerstmann-Straussler disease c.314C>T,p.Pro105Leu rs11538758
18493311
aspsirna3501 GAGUAAGCUAAAAACCAAC
CUCAUUCGAUUUUUGGUUG
27 96 -69 PRNP Prion disease/Gerstmann-Straussler disease c.314C>T,p.Pro105Leu rs11538758
18493311
aspsirna3502 CCGAGUAAGCUAAAAACCA
GGCUCAUUCGAUUUUUGGU
84 92 -8 PRNP Prion disease/Gerstmann-Straussler disease c.314C>T,p.Pro105Leu rs11538758
18493311
aspsirna3503 GCCGAGUAAGCUAAAAACC
CGGCUCAUUCGAUUUUUGG
74 87 -13 PRNP Prion disease/Gerstmann-Straussler disease c.314C>T,p.Pro105Leu rs11538758
18493311