Total number of Results for MAPT are 25
ASPsiRNA ID Pairing of target region (top) and ASP-siRNA (bottom) Efficacy (mut)(%) Efficacy (wt) (%) Diff Gene Disease Mutation RefSNP Analysis Pubmed ID
ASPsiRNA ID Mutant allele/ASP-siRNA Efficacy
for mutant(%)		 Efficacy
for wild (%)		 Relative Difference (%) Gene Disease Mutation RefSNP Analysis Pubmed ID
aspsirna0197 GUGGCCAGAUGGAAGUAAAAUC
CACCGGUCUACCUUCAUUUUAG		 65 60 5 MAPT Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) c.1960G>A,p.Val654Met rs63750570
14754988
aspsirna0198 GUGGCCAGGAGGAAGUAAAAUC
CACCGGUCCUCCUUCAUUUUAG		 77 Poor efficacy High discrimination MAPT Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) c.1960G>A,p.Val654Met rs63750570
14754988
aspsirna0199 GUGGCCAGGUAGAAGUAAAAUC
CACCGGUCCAUCUUCAUUUUAG		 86 Poor efficacy High discrimination MAPT Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) c.1960G>A,p.Val654Met rs63750570
14754988
aspsirna0200 GUGGCCAGGUGAAAGUAAAAUC
CACCGGUCCACUUUCAUUUUAG		 93 80 13 MAPT Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) c.1960G>A,p.Val654Met rs63750570
14754988
aspsirna0207 CAGCCGGGAGUCGGGAAGGUGC
GUCGGCCCUCAGCCCUUCCACG		 43 NA NA MAPT Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) c.1960G>A,p.Val654Met rs63750570
12782788
aspsirna0208 ACGUCCUCGGCGGCGGCAGUGUGC
UGCAGGAGCCGCCGCCGUCACACG		 80 NA NA MAPT Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) c.1960G>A,p.Val654Met rs63750570
12782788
aspsirna0209 ACGUCUCCAUGGCAUCUCAGC
UGCAGAGGUACCGUAGAGUCG		 17 85 -68 MAPT Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) c.1960G>A,p.Val654Met rs63750570
12782788
aspsirna0210 GUGGCCAGAUGGAAGUAAAAUC
CACCGGUCUACCUUCAUUUUAG		 65 60 5 MAPT Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) c.1960G>A,p.Val654Met rs63750570
12782788
aspsirna0211 GUGGCCACAUGGAAGUAAAAUC
CACCGGUGUACCUUCAUUUUAG		 65 0 65 MAPT Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) c.1960G>A,p.Val654Met rs63750570
12782788
aspsirna0212 GUGGCCAGAUGCAAGUAAAAUC
CACCGGUCUACGUUCAUUUUAG		 28 55 -27 MAPT Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) c.1960G>A,p.Val654Met rs63750570
12782788
aspsirna3534 CAGCCGGGAGUCGGGAAGGUGC
GUCGGCCCUCAGCCCUUCCACG		 43 NA NA MAPT Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) c.1960G>A,p.Val654Met rs63750570
US20080176812A1
aspsirna3535 ACGUCCUCGGCGGCGGCAGUGUGC
UGCAGGAGCCGCCGCCGUCACACG		 80 NA NA MAPT Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) c.1960G>A,p.Val654Met rs63750570
US20080176812A1
aspsirna3536 ACGUCUCCAUGGCAUCUCAGC
UGCAGAGGUACCGUAGAGUCG		 17 85 -68 MAPT Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) c.1960G>A,p.Val654Met rs63750570
US20080176812A1
aspsirna3537 GUGGCCAGAUGGAAGUAAAAUC
CACCGGUCUACCUUCAUUUUAG		 65 60 5 MAPT Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) c.1960G>A,p.Val654Met rs63750570
US20080176812A1
aspsirna3538 GUGGCCACAUGGAAGUAAAAUC
CACCGGUGUACCUUCAUUUUAG		 65 0 65 MAPT Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) c.1960G>A,p.Val654Met rs63750570
US20080176812A1
aspsirna3539 GUGGCCAGAUGCAAGUAAAAUC
CACCGGUCUACGUUCAUUUUAG		 28 55 -27 MAPT Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) c.1960G>A,p.Val654Met rs63750570
US20080176812A1
aspsirna3546 CAGCCGGGAGUCGGGAAGGUGC
GUCGGCCCUCAGCCCUUCCACG		 43 NA NA MAPT Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) c.1960G>A,p.Val654Met rs63750570
US20080176812A1
aspsirna3547 ACGUCCUCGGCGGCGGCAGUGUGC
UGCAGGAGCCGCCGCCGUCACACG		 80 NA NA MAPT Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) c.1960G>A,p.Val654Met rs63750570
US20080176812A1
aspsirna3548 ACGUCUCCAUGGCAUCUCAGC
UGCAGAGGUACCGUAGAGUCG		 17 85 -68 MAPT Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) c.1960G>A,p.Val654Met rs63750570
US20080176812A1
aspsirna3549 GUGGCCAGAUGGAAGUAAAAUC
CACCGGUCUACCUUCAUUUUAG		 65 60 5 MAPT Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) c.1960G>A,p.Val654Met rs63750570
US20080176812A1
aspsirna3550 GUGGCCACAUGGAAGUAAAAUC
CACCGGUGUACCUUCAUUUUAG		 65 0 65 MAPT Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) c.1960G>A,p.Val654Met rs63750570
US20080176812A1
aspsirna3551 GUGGCCAGAUGCAAGUAAAAUC
CACCGGUCUACGUUCAUUUUAG		 28 55 -27 MAPT Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) c.1960G>A,p.Val654Met rs63750570
US20080176812A1
aspsirna3552 GUGGCCAGAUGGAAGUAAAAUC
CACCGGUCUACCUUCAUUUUAG		 70 68 2 MAPT Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) c.1960G>A,p.Val654Met rs63750570
US20080176812A1
aspsirna3553 GUGGCCACAUGGAAGUAAAAUC
CACCGGUGUACCUUCAUUUUAG		 55 0 55 MAPT Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) c.1960G>A,p.Val654Met rs63750570
US20080176812A1
aspsirna3554 GUGGCCAGAUGCAAGUAAAAUC
CACCGGUCUACGUUCAUUUUAG		 59 10 49 MAPT Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) c.1960G>A,p.Val654Met rs63750570
US20080176812A1