| ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|---|
| aspsirna2251 | CAUGUUGGAGACUUGCGCA GUACAACCUCUGAACGCGU |
90 | 50 | 40 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | 
|
|
| aspsirna2280 | CAUGUUGGAGACUUGCGCA GUACAACCUCUGAACGCGU |
90 | 30 | 60 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |
|
|
| aspsirna2318 | CAUGUUGGAGACUUGCGCA GUACAACCUCUGAACGCGU |
NA | NA | 15 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |
|
|
| aspsirna2048 | CUCUCCUGUAGCUAACGCC GAGAGGACAUCGAUUGCGG |
30 | 45 | -15 | PPIB/Cyclophilin B | NA | NA | NA |
|
|
| aspsirna0951 | AAAAUCUUAAUGAUACAUU UUUUAGAAUUACUAUGUAA |
10 | 20 | -10 | KRT12 | Meesmann epithelial corneal dystrophy (MECD) | c.404G>C,p.Arg135Thr | rs57218384 |
|
|
| aspsirna3512 | AAAAUCUUAAUGAUACAUU UUUUAGAAUUACUAUGUAA |
10 | 20 | -10 | KRT12 | Meesmann epithelial corneal dystrophy (MECD) | c.404G>C,p.Arg135Thr | rs57218384 |
|
|
| aspsirna0450 | AACAAUAAGUUUGCCCCCU UUGUUAUUCAAACGGGGGA |
0 | 30 | -30 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 |
|
|
| aspsirna0488 | AACAAUAAGUUUGCCCCCU UUGUUAUUCAAACGGGGGA |
0 | 0 | 0 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 |
|
|
| aspsirna0708 | CAUGUUGGAGACUUGCGCA GUACAACCUCUGAACGCGU |
94 | 40 | 54 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 |
|
|
| aspsirna0728 | CAUGUUGGAGACUUGCGCA GUACAACCUCUGAACGCGU |
94 | 40 | 54 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 |
|
|
| aspsirna0904 | AAAGUGGAGCAUUCACACU UUUCACCUCGUAAGUGUGA |
90 | NA | NA | B2M | HLA incompatibility | c.31G>C,p.Ala11Pro | rs10489448 |
|
|
| aspsirna0907 | UUCGAAGCUUGAAGCUAA AAGCUUCGAACUUCGAUU |
89 | NA | NA | B2M | HLA incompatibility | c.31G>C,p.Ala11Pro | rs10489448 |
|
|
| aspsirna0909 | GUGGGAUCGAGACAUCUAA CACCCUAGCUCUGUAGAUU |
82 | NA | NA | B2M | HLA incompatibility | c.31G>C,p.Ala11Pro | rs10489448 |
|
|
| aspsirna0916 | AAAGUGGAGCAUUCACACU UUUCACCUCGUAAGUGUGA |
89 | NA | NA | B2M | HLA incompatibility | c.31G>C,p.Ala11Pro | rs10489448 |
|
|
| aspsirna0919 | UUCGAAGCUUGAAGCUAA AAGCUUCGAACUUCGAUU |
88 | NA | NA | B2M | HLA incompatibility | c.31G>C,p.Ala11Pro | rs10489448 |
|
|
| aspsirna0921 | GUGGGAUCGAGACAUCUAA CACCCUAGCUCUGUAGAUU |
80 | NA | NA | B2M | HLA incompatibility | c.31G>C,p.Ala11Pro | rs10489448 |
|
|
| aspsirna3667 | GGUUGGAGGAGAGAUGAUA CCAACCUCCUCUCUAGUAU |
90 | 61 | 29 | PPIB/Cyclophilin B | PPIB-Related Osteogenesis Imperfecta (Type IX) | NA | NA |
|
|
| aspsirna0932 | CUGCUGACAAAGAUGCUGU GACGACUGUUUCUACGACA |
85 | 90 | -5 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.281G>C (p.Gly94Ala) | rs12191243 |
|
