Total number of Results for G6C are 11
ASPsiRNA ID Pairing of target region (top) and ASP-siRNA (bottom) Efficacy (mut)(%) Efficacy (wt) (%) Diff Gene Disease Mutation RefSNP Analysis Pubmed ID
ASPsiRNA ID Mutant allele/ASP-siRNA Efficacy
for mutant(%)		 Efficacy
for wild (%)		 Relative Difference (%) Gene Disease Mutation RefSNP Analysis Pubmed ID
aspsirna0710 UGUUGGAGACUUGCGCAAU
ACAACCUCUGAACGCGUUA		 90 35 55 SOD1 Amyotrophic Lateral Sclerosis (ALS) c.256G>C, p.Gly86Arg rs12191243
16965178
aspsirna0730 UGUUGGAGACUUGCGCAAU
ACAACCUCUGAACGCGUUA		 90 35 55 SOD1 Amyotrophic Lateral Sclerosis (ALS) c.256G>C, p.Gly86Arg rs12191243
16965178
aspsirna0931 GCAGCAGCAGCAGCGGGAC
CGUCGUCGUCGUCGCCCUG		 80 80 0 ATXN3 Machado-Joseph Disease (MJD)/Spinocerebellar ataxia type 3 (SCA3) c.209_211CAG(8_36),(p.Gln298_Gln305=) rs19392292
15236410
aspsirna0953 AAUCUUAAUGAUACAUUAG
UUAGAAUUACUAUGUAAUC		 79 50 29 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna2253 UGUUGGAGACUUGCGCAAU
ACAACCUCUGAACGCGUUA		 90 70 20 SOD1 Amyotrophic Lateral Sclerosis (ALS) c.256G>C,p.Gly86Arg rs12191243
US2007/0259827A1
aspsirna2282 UGUUGGAGACUUGCGCAAU
ACAACCUCUGAACGCGUUA		 98 30 68 SOD1 Amyotrophic Lateral Sclerosis (ALS) c.256G>C,p.Gly86Arg rs12191243
US2007/0259827A1
aspsirna2320 UGUUGGAGACUUGCGCAAU
ACAACCUCUGAACGCGUUA		 NA NA 9 SOD1 Amyotrophic Lateral Sclerosis (ALS) c.256G>C,p.Gly86Arg rs12191243
US2007/0259827A1
aspsirna3166 UCCCUCCUGCAGGCUGCGUGUU
AGGGAGGACGUCCGACGCACAA 		55 25 30 HTT Huntington disease (HD) rs362268 rs362268
25849618
aspsirna3174 UCCCUCCUGCAGGCUGCGUGUU
AGGGAGGACGUCCGACGCACAA 		60 25 35 HTT Huntington disease (HD) rs362268 rs362268
25849618
aspsirna3514 AAUCUUAAUGAUACAUUAG
UUAGAAUUACUAUGUAAUC		 79 50 29 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3752 AAAGUUGCGCGGAGGAGUU
UUUCAACGCGCCUGCUCAA		 90 35 55 PPIB/Cyclophilin B PPIB-Related Osteogenesis Imperfecta (Type IX) NA NA
16489337