| aspsirna3537 |
GUGGCCAGAUGGAAGUAAAAUC
CACCGGUCUACCUUCAUUUUAG |
65 |
60 |
5 |
MAPT |
Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) |
c.1960G>A,p.Val654Met |
rs63750570 |
|
US20080176812A1 |
| aspsirna3549 |
GUGGCCAGAUGGAAGUAAAAUC
CACCGGUCUACCUUCAUUUUAG |
65 |
60 |
5 |
MAPT |
Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) |
c.1960G>A,p.Val654Met |
rs63750570 |
|
US20080176812A1 |
| aspsirna3552 |
GUGGCCAGAUGGAAGUAAAAUC
CACCGGUCUACCUUCAUUUUAG |
70 |
68 |
2 |
MAPT |
Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) |
c.1960G>A,p.Val654Met |
rs63750570 |
|
US20080176812A1 |
| aspsirna3555 |
GUGGCCAGAUGGAAGUAAAAUC
CACCGGUCUACCUUCAUUUUAG |
70 |
68 |
2 |
TOR1A |
Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) |
NA |
NA |
|
US20080176812A1 |
| aspsirna2022 |
UUUAUAAGGAUCUCUCUGA
AAAUAUUCCUAGAGAGACU |
82 |
30 |
52 |
P. luciferase |
NA |
NA |
NA |
|
US2005/0176045A1 |
| aspsirna3194 |
UCGACAUGUCCUUCCAGCA
AGCUGUACAGGAAGGUCGU |
90 |
10 |
80 |
TP63 |
Ectrodactyly-Ectodermal Dysplasia-Clefting syndrome 3 (EEC3) |
p.Arg132His,c.394G>A |
rs19392114 |
|
26891374 |
| aspsirna3079 |
AGGUGCAUGUUUGUGCCUGU
UCCACGUACAAACACGGACA |
30 |
20 |
10 |
TP53 |
Cancer |
NC_000005.10:g.144594367C>A |
rs57315468 |
|
26700961 |
| aspsirna3085 |
AGGUGCAUGUUUGUGCCUGU
UCCACGUACAAACACGGACA |
35 |
20 |
15 |
TP53 |
Cancer |
NC_000005.10:g.144594367C>A |
rs57315468 |
|
26700961 |
| aspsirna3091 |
AGGUGCAUGUUUGUGCCUGU
UCCACGUACAAACACGGACA |
34 |
20 |
14 |
TP53 |
Cancer |
NC_000005.10:g.144594367C>A |
rs57315468 |
|
26700961 |
| aspsirna1907 |
CACCCUCAGGUGAGGGUGGGG
GUGGGAGUCCACUCCCACCCC |
Moderate efficacy |
Moderate efficacy |
Poor discrimination |
Myh6 |
Human hypertrophic cardiomyopathy (HCM) |
c.2384G>A,p.Arg795Gln |
rs26760690 |
|
24092743 |
| aspsirna0670 |
CAGCAGCAACAGCAGCAGCAGC
GUCGUCGUUGUCGUCGUCGUCG |
40 |
20 |
20 |
HTT |
Huntington disease (HD) |
c.52CAG(36_39) |
rs19392295 |
|
22939619 |
| aspsirna0608 |
UUCUCAGCUGGCCUCUUAC
AAGAGUCGACCGGAGAAUG |
35 |
0 |
35 |
KRT9 |
Epidermolytic palmoplantar keratoderma (EPPK) |
c.488G>A,p.Arg163Gln |
rs57758262 |
|
22402445 |
| aspsirna0321 |
GCCUGGUAUUCCCAGGCUC
CGGACCAUAAGGGUCCGAG |
50 |
11 |
39 |
COL7A1 |
Dominant dystrophic epidermolysis bullosa(DDEB) |
c.6127G>A,p.Gly2043Arg |
rs12191283 |
|
22336946 |
| aspsirna0254 |
ACUACAGCAUUGCUCAGUA
UGAUGUCGUAACGAGUCAU |
77 |
65 |
12 |
LRRK2 |
Parkinsons disease (PD) |
c.6055G>A,p.Gly2019Ser |
rs34637584 |
|
22031823 |
| aspsirna0860 |
CAGCCAUGAACAAUGUCCA
GUCGGUACUUGUUACAGGU |
NA |
10 |
NA |
ATXN7 |
Spino Cerebellar Ataxia type-7 (SCA-7) |
c.88_90CAG(7_17) |
rs193922929 |
|
19789634 |
| aspsirna0889 |
CUCAAAAACAAGUUUGCCU
GAGUUUUUGUUCAAACGGA |
56 |
25 |
31 |
KRT6a |
Pachyonychia congenita (PC) |
c.513C>A,p.Asn171Lys |
rs59685571 |
|
17914454 |
| aspsirna3632 |
UCAGAGAGAUCCUCAUAAA
AGUCUUUCUAGGAGUAUUU |
90 |
92 |
-2 |
PPIB/Cyclophilin B |
PPIB-Related Osteogenesis Imperfecta (Type IX) |
NA |
NA |
|
16489337 |
| aspsirna3708 |
GGUUGGAGGAGAGAUGAUA
CCAACUUCCUCUCUACUAU |
90 |
92 |
-2 |
PPIB/Cyclophilin B |
PPIB-Related Osteogenesis Imperfecta (Type IX) |
NA |
NA |
|
16489337 |
| aspsirna0197 |
GUGGCCAGAUGGAAGUAAAAUC
CACCGGUCUACCUUCAUUUUAG |
65 |
60 |
5 |
MAPT |
Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) |
c.1960G>A,p.Val654Met |
rs63750570 |
|
14754988 |
| aspsirna0210 |
GUGGCCAGAUGGAAGUAAAAUC
CACCGGUCUACCUUCAUUUUAG |
65 |
60 |
5 |
MAPT |
Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) |
c.1960G>A,p.Val654Met |
rs63750570 |
|
12782788 |
