ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna0937 | AUGACGACGCUGGUAUAGG UACUGCUGCGACCAUAUCC |
73 | 33 | 40 | AR | Spinal and Bulbar Muscular Atrophy, X-linked 1; SMAX1/Kennedy’s disease | c.172_174CAG(10_36) (p.Gln69_Gln80del)] | rs19392293 | ||
aspsirna0938 | AUGACGACGCUGGUAUAGG UACUGCUGCGACCAUAUCC |
73 | 35 | 38 | AR | Spinal and Bulbar Muscular Atrophy, X-linked 1; SMAX1/Kennedy’s disease | c.172_174CAG(10_36) (p.Gln69_Gln80del)] | rs19392293 | ||
aspsirna0939 | AUGUCCUUCCGGCAGCAGC UACAGGAAGGCCGUCGUCG |
70 | 45 | 25 | AR | Spinal and Bulbar Muscular Atrophy, X-linked 1; SMAX1/Kennedy’s disease | c.172_174CAG(10_36) (p.Gln69_Gln80del)] | rs19392293 | ||
aspsirna0940 | AUGUCCUGCCAGCAGCUGC UACAGGACGGUCGUCGACG |
82 | 23 | 59 | AR | Spinal and Bulbar Muscular Atrophy, X-linked 1; SMAX1/Kennedy’s disease | c.172_174CAG(10_36) (p.Gln69_Gln80del)] | rs19392293 | ||
aspsirna0941 | AUGUCCGUCCAGCUGCAGC UACAGGCAGGUCGACGUCG |
40 | 20 | 20 | AR | Spinal and Bulbar Muscular Atrophy, X-linked 1; SMAX1/Kennedy’s disease | c.172_174CAG(10_36) (p.Gln69_Gln80del)] | rs19392293 | ||
aspsirna0942 | AUGGCCUUCCUGCAGCAGC UACCGGAAGGACGUCGUCG |
77 | 12 | 65 | AR | Spinal and Bulbar Muscular Atrophy, X-linked 1; SMAX1/Kennedy’s disease | c.172_174CAG(10_36) (p.Gln69_Gln80del)] | rs19392293 | ||
aspsirna0943 | AUGUCCUUCAAGGAGCAGC UACAGGAAGUUCCUCGUCG |
42 | 50 | -8 | AR | Spinal and Bulbar Muscular Atrophy, X-linked 1; SMAX1/Kennedy’s disease | c.172_174CAG(10_36) (p.Gln69_Gln80del)] | rs19392293 | ||
aspsirna0944 | AUGUCCAUCCACCAGCAGC UACAGGUAGGUGGUCGUCG |
86 | 32 | 54 | AR | Spinal and Bulbar Muscular Atrophy, X-linked 1; SMAX1/Kennedy’s disease | c.172_174CAG(10_36) (p.Gln69_Gln80del)] | rs19392293 | ||
aspsirna0945 | AUGACCUUCUAGCAGCAGC UACUGGAAGAUCGUCGUCG |
70 | 12 | 58 | AR | Spinal and Bulbar Muscular Atrophy, X-linked 1; SMAX1/Kennedy’s disease | c.172_174CAG(10_36) (p.Gln69_Gln80del)] | rs19392293 | ||
aspsirna0946 | GGAUGAGGAACAGCAACGU CCUACUCCUUGUCGUUGCA |
9 | 7 | 2 | AR | Spinal and Bulbar Muscular Atrophy, X-linked 1; SMAX1/Kennedy’s disease | c.172_174CAG(10_36) (p.Gln69_Gln80del)] | rs19392293 | ||
aspsirna0947 | GAGCAGCAGCAGCAGCAGA CUCGUCGUCGUCGUCGUCU |
50 | 43 | 7 | AR | Spinal and Bulbar Muscular Atrophy, X-linked 1; SMAX1/Kennedy’s disease | c.172_174CAG(10_36) (p.Gln69_Gln80del)] | rs19392293 |