ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna0872 | GUCCCGGCAGGUGGUGGAGC CAGGGCCGUCCACCACCUCG |
60 | 15 | 45 | PSEN1 | Alzheimers disease | c.458C>G, p.Leu153Val | 63751441 | ||
aspsirna0873 | GACCCGGCAGGUGGUGGAGCA CUGGGCCGUCCACCACCUCGU |
70 | 20 | 50 | PSEN1 | Alzheimers disease | c.458C>G, p.Leu153Val | 63751441 | ||
aspsirna0874 | GUCCCGGCAGGUGGUGGAGC CAGGGCCGUCCACCACCUCG |
70 | 10 | 60 | PSEN1 | Alzheimers disease | c.458C>G, p.Leu153Val | 63751441 | ||
aspsirna0875 | GACCCGGCAGGUGGUGGAGCA CUGGGCCGUCCACCACCUCGU |
80 | 20 | 60 | PSEN1 | Alzheimers disease | c.458C>G, p.Leu153Val | 63751441 |