ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna0540 | UUCAAUAUAAAGGCUGGCG AAGUUAUAUUUCCGACCGC |
37 | 8 | 29 | LRRK2 | Parkinsons disease (PD) | c.4321C>G,p.Arg1441Gly | rs33939927 | ![]() |
|
aspsirna0541 | GCUGGCGCUUCUUCUUCCC CGACCGCGAAGAAGAAGGG |
71 | 10 | 61 | LRRK2 | Parkinsons disease (PD) | c.4321C>G,p.Arg1441Gly | rs33939927 | ![]() |
|
aspsirna0542 | UAAAGGCUGGCGCUUCUUC AUUUCCGACCGCGAAGAAG |
20 | 6 | 14 | LRRK2 | Parkinsons disease (PD) | c.4321C>G,p.Arg1441Gly | rs33939927 | ![]() |
|
aspsirna0543 | UAAAGGCUUGCGCUUCUUC AUUUCCGAACGCGAAGAAG |
63 | 75 | -12 | LRRK2 | Parkinsons disease (PD) | c.4321C>T,p.Arg1441Cys | rs33939927 | ![]() |
|
aspsirna0544 | GCUGACUACAGCAUUGCUC CGACUGAUGUCGUAACGAG |
40 | 86 | -46 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 | ![]() |
|
aspsirna0545 | CUACAGCAUUGCUCAGUAC GAUGUCGUAACGAGUCAUG |
29 | 4 | 25 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 | ![]() |
|
aspsirna0546 | UACAGCAUUGCUCAGUACU AUGUCGUAACGAGUCAUGA |
46 | 14 | 32 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 | ![]() |
|
aspsirna0547 | AGAUUGCUGACUACAGCAU UCUAACGACUGAUGUCGUA |
40 | 7 | 33 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 | ![]() |
|
aspsirna0548 | AAGAUUGCUGACUACAGCA UUCUAACGACUGAUGUCGU |
40 | 0 | 40 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 | ![]() |