ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna0657 | CAGCAGCAGCUGCAGCAGC GUCGUCGUCGACGUCGUCG |
30 | 20 | 10 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0658 | GUCUGUUACUAAGUGUGCC CAGACAAUGAUUCACACGG |
50 | 10 | 40 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0659 | AACAGUAGCAACAGCUGC UUGUCAUCGUUGUCGACG |
20 | 15 | 5 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0660 | CAGCAGCAGCAGCAGUAGC GUCGUCGUCGUCGUCAUCG |
20 | 13 | 7 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0661 | CAGUAGCAGCAGCAGCAGC GUCAUCGUCGUCGUCGUCG |
34 | 20 | 14 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0662 | CAGCAGCAGUUGCAGCAGC GUCGUCGUCAACGUCGUCG |
58 | 22 | 36 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0663 | AAGUCCUUCCAGCAGCUGC UUCAGGAAGGUCGUCGACG |
43 | 10 | 33 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0664 | AAGUCCUUCCAGCUGCAGC UUCAGGAAGGUCGACGUCG |
5 | 11 | -6 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0665 | AAGUCCUUCCUGCAGCAGC UUCAGGAAGGACGUCGUCG |
25 | 13 | 12 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0666 | AAGUCCUUCUAGCAGCAGC UUCAGGAAGAUCGUCGUCG |
82 | 18 | 64 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0667 | AAGUCCAUCCAGCAGCAGC UUCAGGUAGGUCGUCGUCG |
82 | 5 | 77 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0668 | AAGACCUUCCAGCAGCAGC UUCUGGAAGGUCGUCGUCG |
52 | 48 | 4 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0669 | AAGUCCUUCCAGCAGCAGC UUCAGGAAGGUCGUCGUCG |
40 | 25 | 15 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 |