ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna2170 | GGGACAGUAAUUCAACGCUU CCCUGUCAUUAAGUUGCGAA |
85 | 5 | 80 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2171 | GUAAUUCAACGCUAGAA CAUUAAGUUGCGAUCUU |
90 | 10 | 80 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2172 | GUACUUCAACGCUAGAAGAU CAUGAAGUUGCGAUCUUCUA |
88 | 15 | 73 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2173 | GGGACAGUACUUCAACGCUU CCCUGUCAUGAAGUUGCGAA |
80 | 5 | 75 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2174 | CCCUCAUCCACUGUGUGCA GGGAGUAGGUGACACACGU |
90 | 10 | 80 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2175 | CCCUCAUCUACUGUGUGCAU GGGAGUAGAUGACACACGUA |
75 | 40 | 35 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2176 | GUUUGAGCUAAUGUAUGUG CAAACUCGAUUACAUACAC |
60 | 8 | 52 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2177 | GUUUGAGCUGAUGUAUGUGU CAAACUCGACUACAUACACA |
70 | 20 | 50 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2178 | GGAAGUCUGCGCCCUUGUG CCUUCAGACGCGGGAACAC |
85 | 55 | 30 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna2179 | GGAAGUCUGUGCCCUUGUGU CCUUCAGACACGGGAACACA |
76 | 45 | 31 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna3435 | GGGACAGUAAUUCAACGCUU CCCUGUCAUUAAGUUGCGAA |
85 | 10 | 75 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3436 | GUAAUUCAACGCUAGAA CAUUAAGUUGCGAUCUU |
90 | 10 | 80 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3437 | GUACUUCAACGCUAGAAGAU CAUGAAGUUGCGAUCUUCUA |
88 | 15 | 73 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3438 | GGGACAGUACUUCAACGCUU CCCUGUCAUGAAGUUGCGAA |
80 | 5 | 75 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3439 | CCCUCAUCCACUGUGUGCA GGGAGUAGGUGACACACGU |
90 | 10 | 80 | HTT | Huntington disease (HD) | NM_002111.7:c.6931T>C | rs362331 | ||
aspsirna3440 | CCCUCAUCUACUGUGUGCAU GGGAGUAGAUGACACACGUA |
75 | 40 | 35 | HTT | Huntington disease (HD) | NM_002111.7:c.6931T>C | rs362331 | ||
aspsirna3441 | GUUUGAGCUAAUGUAUGUG CAAACUCGAUUACAUACAC |
60 | 8 | 52 | HTT | Huntington disease (HD) | NM_002111.7:c.8163G>A | rs2276881 | ||
aspsirna3442 | GUUUGAGCUGAUGUAUGUGU CAAACUCGACUACAUACACA |
70 | 20 | 50 | HTT | Huntington disease (HD) | NM_002111.7:c.8163G>A | rs2276881 | ||
aspsirna3443 | GGAAGUCUGCGCCCUUGUG CCUUCAGACGCGGGAACAC |
85 | 55 | 30 | HTT | Huntington disease (HD) | NM_002111.6:c.9810C>T | rs362307 | ||
aspsirna3444 | GGAAGUCUGUGCCCUUGUGU CCUUCAGACACGGGAACACA |
76 | 45 | 31 | HTT | Huntington disease (HD) | NM_002111.6:c.9810C>T | rs362307 | ||
aspsirna3445 | GGGACAGUAAUUCAACGCUU CCCUGUCAUUAAGUUGCGAA |
80 | 20 | 60 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3446 | GUAAUUCAACGCUAGAA CAUUAAGUUGCGAUCUU |
100 | 40 | 60 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3447 | GUACUUCAACGCUAGAAGAU CAUGAAGUUGCGAUCUUCUA |
78 | 20 | 58 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3448 | GGGACAGUACUUCAACGCUU CCCUGUCAUGAAGUUGCGAA |
80 | 5 | 75 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3449 | CCCUCAUCCACUGUGUGCA GGGAGUAGGUGACACACGU |
90 | 10 | 80 | HTT | Huntington disease (HD) | NM_002111.7:c.6931T>C | rs362331 | ||
aspsirna3450 | CCCUCAUCUACUGUGUGCAU GGGAGUAGAUGACACACGUA |
75 | 40 | 35 | HTT | Huntington disease (HD) | NM_002111.7:c.6931T>C | rs362331 | ||
aspsirna3451 | GUUUGAGCUAAUGUAUGUG CAAACUCGAUUACAUACAC |
60 | 8 | 52 | HTT | Huntington disease (HD) | NM_002111.7:c.8163G>A | rs2276881 | ||
aspsirna3452 | GUUUGAGCUGAUGUAUGUGU CAAACUCGACUACAUACACA |
70 | 20 | 50 | HTT | Huntington disease (HD) | NM_002111.7:c.8163G>A | rs2276881 | ||
aspsirna3453 | GGAAGUCUGCGCCCUUGUG CCUUCAGACGCGGGAACAC |
85 | 55 | 30 | HTT | Huntington disease (HD) | NM_002111.6:c.9810C>T | rs362307 | ||
aspsirna3454 | GGAAGUCUGUGCCCUUGUGU CCUUCAGACACGGGAACACA |
76 | 45 | 31 | HTT | Huntington disease (HD) | NM_002111.6:c.9810C>T | rs362307 | ||
aspsirna3455 | GGGACAGUAAUUCAACGCUU CCCUGUCAUUAAGUUGCGAA |
98 | 60 | 38 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3456 | GUAAUUCAACGCUAGAA CAUUAAGUUGCGAUCUU |
100 | 40 | 60 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3457 | GUACUUCAACGCUAGAAGAU CAUGAAGUUGCGAUCUUCUA |
78 | 20 | 58 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3458 | GGGACAGUACUUCAACGCUU CCCUGUCAUGAAGUUGCGAA |
97 | 67 | 30 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3459 | CCCUCAUCCACUGUGUGCA GGGAGUAGGUGACACACGU |
100 | 10 | 90 | HTT | Huntington disease (HD) | NM_002111.7:c.6931T>C | rs362331 | ||
aspsirna3460 | CCCUCAUCUACUGUGUGCAU GGGAGUAGAUGACACACGUA |
75 | 40 | 35 | HTT | Huntington disease (HD) | NM_002111.7:c.6931T>C | rs362331 | ||
aspsirna3461 | GUUUGAGCUAAUGUAUGUG CAAACUCGAUUACAUACAC |
60 | 8 | 52 | HTT | Huntington disease (HD) | NM_002111.7:c.8163G>A | rs2276881 | ||
aspsirna3462 | GUUUGAGCUGAUGUAUGUGU CAAACUCGACUACAUACACA |
70 | 20 | 50 | HTT | Huntington disease (HD) | NM_002111.7:c.8163G>A | rs2276881 | ||
aspsirna3463 | GGAAGUCUGCGCCCUUGUG CCUUCAGACGCGGGAACAC |
85 | 55 | 30 | HTT | Huntington disease (HD) | NM_002111.6:c.9810C>T | rs362307 | ||
aspsirna3464 | GGAAGUCUGUGCCCUUGUGU CCUUCAGACACGGGAACACA |
76 | 45 | 31 | HTT | Huntington disease (HD) | NM_002111.6:c.9810C>T | rs362307 | ||
aspsirna3465 | GGGACAGUAAUUCAACGCUU CCCUGUCAUUAAGUUGCGAA |
98 | 60 | 38 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3466 | GUAAUUCAACGCUAGAA CAUUAAGUUGCGAUCUU |
100 | 40 | 60 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3467 | GUACUUCAACGCUAGAAGAU CAUGAAGUUGCGAUCUUCUA |
78 | 20 | 58 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3468 | GGGACAGUACUUCAACGCUU CCCUGUCAUGAAGUUGCGAA |
97 | 67 | 30 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3469 | CCCUCAUCCACUGUGUGCA GGGAGUAGGUGACACACGU |
100 | 10 | 90 | HTT | Huntington disease (HD) | NM_002111.7:c.6931T>C | rs362331 | ||
aspsirna3470 | CCCUCAUCUACUGUGUGCAU GGGAGUAGAUGACACACGUA |
75 | 40 | 35 | HTT | Huntington disease (HD) | NM_002111.7:c.6931T>C | rs362331 | ||
aspsirna3471 | GUUUGAGCUAAUGUAUGUG CAAACUCGAUUACAUACAC |
60 | 8 | 52 | HTT | Huntington disease (HD) | NM_002111.7:c.8163G>A | rs2276881 | ||
aspsirna3472 | GUUUGAGCUGAUGUAUGUGU CAAACUCGACUACAUACACA |
70 | 20 | 50 | HTT | Huntington disease (HD) | NM_002111.7:c.8163G>A | rs2276881 | ||
aspsirna3473 | GGAAGUCUGCGCCCUUGUG CCUUCAGACGCGGGAACAC |
85 | 55 | 30 | HTT | Huntington disease (HD) | NM_002111.6:c.9810C>T | rs362307 | ||
aspsirna3474 | GGAAGUCUGUGCCCUUGUGU CCUUCAGACACGGGAACACA |
76 | 45 | 31 | HTT | Huntington disease (HD) | NM_002111.6:c.9810C>T | rs362307 | ||
aspsirna3475 | GGGACAGUAAUUCAACGCUU CCCUGUCAUUAAGUUGCGAA |
98 | 28 | 70 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3476 | GUAAUUCAACGCUAGAA CAUUAAGUUGCGAUCUU |
100 | 40 | 60 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3477 | GUACUUCAACGCUAGAAGAU CAUGAAGUUGCGAUCUUCUA |
78 | 20 | 58 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3478 | GGGACAGUACUUCAACGCUU CCCUGUCAUGAAGUUGCGAA |
97 | 30 | 67 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3479 | CCCUCAUCCACUGUGUGCA GGGAGUAGGUGACACACGU |
100 | 10 | 90 | HTT | Huntington disease (HD) | NM_002111.7:c.6931T>C | rs362331 | ||
aspsirna3480 | CCCUCAUCUACUGUGUGCAU GGGAGUAGAUGACACACGUA |
75 | 40 | 35 | HTT | Huntington disease (HD) | NM_002111.7:c.6931T>C | rs362331 | ||
aspsirna3481 | GUUUGAGCUAAUGUAUGUG CAAACUCGAUUACAUACAC |
60 | 8 | 52 | HTT | Huntington disease (HD) | NM_002111.7:c.8163G>A | rs2276881 | ||
aspsirna3482 | GUUUGAGCUGAUGUAUGUGU CAAACUCGACUACAUACACA |
70 | 20 | 50 | HTT | Huntington disease (HD) | NM_002111.7:c.8163G>A | rs2276881 | ||
aspsirna3483 | GGAAGUCUGCGCCCUUGUG CCUUCAGACGCGGGAACAC |
85 | 55 | 30 | HTT | Huntington disease (HD) | NM_002111.6:c.9810C>T | rs362307 | ||
aspsirna3484 | GGAAGUCUGUGCCCUUGUGU CCUUCAGACACGGGAACACA |
76 | 45 | 31 | HTT | Huntington disease (HD) | NM_002111.6:c.9810C>T | rs362307 | ||
aspsirna3485 | GGGACAGUAAUUCAACGCUU CCCUGUCAUUAAGUUGCGAA |
70 | 30 | 40 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3486 | GUAAUUCAACGCUAGAA CAUUAAGUUGCGAUCUU |
98 | 40 | 58 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3487 | GUACUUCAACGCUAGAAGAU CAUGAAGUUGCGAUCUUCUA |
88 | 20 | 68 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3488 | GGGACAGUACUUCAACGCUU CCCUGUCAUGAAGUUGCGAA |
97 | 67 | 30 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ||
aspsirna3489 | CCCUCAUCCACUGUGUGCA GGGAGUAGGUGACACACGU |
100 | 10 | 90 | HTT | Huntington disease (HD) | NM_002111.7:c.6931T>C | rs362331 | ||
aspsirna3490 | CCCUCAUCUACUGUGUGCAU GGGAGUAGAUGACACACGUA |
75 | 40 | 35 | HTT | Huntington disease (HD) | NM_002111.7:c.6931T>C | rs362331 | ||
aspsirna3491 | GUUUGAGCUAAUGUAUGUG CAAACUCGAUUACAUACAC |
60 | 0 | 60 | HTT | Huntington disease (HD) | NM_002111.7:c.8163G>A | rs2276881 | ||
aspsirna3492 | GUUUGAGCUGAUGUAUGUGU CAAACUCGACUACAUACACA |
70 | 30 | 40 | HTT | Huntington disease (HD) | NM_002111.7:c.8163G>A | rs2276881 | ||
aspsirna3493 | GGAAGUCUGCGCCCUUGUG CCUUCAGACGCGGGAACAC |
85 | 55 | 30 | HTT | Huntington disease (HD) | NM_002111.6:c.9810C>T | rs362307 | ||
aspsirna3494 | GGAAGUCUGUGCCCUUGUGU CCUUCAGACACGGGAACACA |
82 | 60 | 22 | HTT | Huntington disease (HD) | NM_002111.6:c.9810C>T | rs362307 |