Genomics and Informatics Solutions for Integrating Biology
Here we provide links to all the web servers/tools which are developed for peptides with special emphasis on therapeutic peptides. This will help researchers to find a tool which will be relevant to their area of peptide research.
Peptide Prediction Servers
| No. | Name | Description |
| AntiCP | A web server for designing and discovering novel anticancer peptides. | |
| ToxinPred | Insilico approach for predicting toxicity of peptides and proteins. | |
| AntiBP2 | Server for antibacterial peptide prediction. | |
| ClassAMP | A prediction tool for classification of AMPs. | |
| FoldAmyloid | Server for prediction of amyloidogenic regions in the protein chain. | |
| TumorHPD | Server for designing of tumor homing peptides. | |
| HLP | A web server for predicting half-life of peptides in intestine like environment | |
| CellPPD | Server for designing of cell penetrating peptides. | |
| SignalP 4.1 | Server for predicting the presence and location of signal peptide cleavage sites in amino acid sequences from different organisms: Gram-positive prokaryotes, Gram-negative prokaryotes, and eukaryotes. | |
| PrediSi | Software tool for predicting signal peptide sequences and their cleavage positions in bacterial and eukaryotic proteins | |
| HemoPI | A Server for prediction of hemolytic potency of peptides. | |
| AntiAngioPred | A Server for prediction and designing of antiangiogenic peptides. | |
| ChloroP 1.1 | The ChloroP server predicts the presence of chloroplast transit peptides (cTP) in protein sequences and the location of potential cTP cleavage sites. | |
| PEPstr | A Server for prediction of tertiary structure prediction of peptides. | |
| PEPstrMOD | Structure prediction of peptides containing natural, non-natural and modified residues. | |
| PEP-FOLD | A de novo approach for predicting peptide structures from amino acid sequences. | |
| Antigenic Peptide Prediction | A de novo This program predicts those segments from within a protein sequence that are likely to be antigenic by eliciting an antibody response.. | |
| PEP2D | A web server for predicting secondary structure of peptides. | |
| ProPred | MHC Class-II binding peptide prediction server. | |
| MHC2Pred | SVM based method for prediction of promiscuous MHC Class II binders | |
| QSPpred | Server for predicting quorum sensing peptides | |
| IL4pred | In silico platform for designing and disovering of interleukin-4 inducing peptides. | |
| dPABBs | A server for predicting and designing biofilm active peptides. | |
| IFNepitope | A server for predicting and designing interferon-gamma inducing peptides. |
Peptide Databases
| S.No. | Database Name | Description |
| BIOPEP | BIOPEP database and other programs for processing bioactive peptide sequences | |
| Brainpeps | blood-brain barrier properties of peptides | |
| CAMP | Collection of sequences and structures of antimicrobial peptides | |
| CPPsite | A curated database of cell penetrating peptides | |
| EROP-Moscow | The EROP-Moscow oligopeptide database | |
| MilkAMP | a comprehensive database of antimicrobial peptides of dairy origin | |
| RAPD | Recombinantly-produced Antimicrobial Peptides Database | |
| TumorHoPe | A Database of Tumor Homing Peptides | |
| Hemolytik | Database of hemolytic peptides | |
| SPdb | a signal peptide resource | |
| Quorumpeps | chemical space, microbial origin and functionality of quorum sensing peptides | |
| YADAMP | Anti-microbial Database | |
| PeptideDB | Bioactive peptide database in Metazoa | |
| IEDB | Immune Epitope Database | |
| SYFPEITHI | database for MHC ligands and peptide motifs | |
| MHCBN 4.0 | MHC binding and non-binding peptides | |
| AntiJen | quantitative binding data for peptides binding to MHC Ligand, TCR-MHC Complexes, T Cell Epitope, TAP, B Cell Epitope molecules and immunological Protein-Protein interactions | |
| Bcipep | Database of B-cell epitopes | |
| ACEpepDB | Food derived antihypertensive peptides | |
| Human Urine Peptide Database | A database of naturally occurring human urinary peptides and proteins for use in clinical applications | |
| PepBank | peptides based on sequence text mining and public peptide data sources. | |
| PhytAMP | database dedicated to antimicrobial plant peptides | |
| EPIMHC | a curated database of MHC-binding peptides for customized computational vaccinology. | |
| Parapep | repository of experimentally validated anti-parasitic peptides | |
| CancerPPD | Database of Anticancer peptides and proteins | |
| PEPlife | A database of half life of peptides | |
| DADP | Database of Anuran Defense Peptides | |
| DAMPD | Dragon Antimicrobial Peptide Database | |
| APD2 | The Antimicrobial Peptide Database | |
| AMPer | A Database and an Automated Discovery Tool for Gene-Coded Antimicrobial Peptides | |
| DEFENSINS Knowledgebase | manually curated database and information source devoted to the defensin family of antimicrobial peptides | |
| NeuroPep | A comprehensive resource of Neuropeptides | |
| NeuroPedia | neuropeptide database and spectral library. | |
| MPID-T2 | MHC-Peptide Interaction Database-TR version 2 | |
| Signal Peptide website | An Information Platform for Signal Sequences and Signal Peptides | |
| SwePep | Database designed for endogenous peptides and mass spectrometry | |
| AVPdb | database of experimentally validated antiviral peptides | |
| Peptaibol | Peptaibols generally exhibit antimicrobial activity and are referred to as antibiotic peptides | |
| PEPTIDOME DB | a comprehensive fact-database for endogenous peptides | |
| NORINE | a database of nonribosomal peptides | |
| ConoServer | a database for conopeptides which are peptides expressed by carnivorous marine cone snails | |
| BaAMPs | Biofilm-active AMPs database: antimicrobial peptides (AMPs) specifically tested against microbial biofilms. | |
| BACTIBASE | data repository of bacteriocin natural antimicrobial peptides | |
| LAMP | A database linking antimicrobial peptide. | |
| DBAASP | Database of Antimicrobial Activity and Structure of Peptides | |
| HIPdb | A Database of Experimentally Validated HIV Inhibiting Peptides | |
| HMRBase | A database of hormones and their receptors | |
| BactPepDB | a database of predicted peptides from a exhaustive survey of complete prokaryote genomes | |
| Transitpep | peptides are responsible for the transport of a protein encoded by a nuclear gene to a particular organell | |
| Arabidopsis Unannotated Secreted Peptide Database | This is a searchable database of bioinformatic predictions of putative intergenic unannotated secreted peptides from Arabidopsis thaliana. | |
| MHCPEP | database of MHC-binding peptides. | |
| JenPep | database of quantitative functional peptide data for immunology | |
| PenBase | the shrimp antimicrobial peptide penaeidin database | |
| database of circulating human peptides | Composition of the peptide fraction in human blood plasma: database of circulating human peptides | |
| Database of biologically active peptide sequences | Database of biologically active peptide sequences | |
| MPID | MHC-Peptide Interaction Database for sequence-structure-function information on peptides binding to MHC molecules | |
| SAPD | Synthetic Antibiotic Peptides Database | |
| CoPS | Comprehensive Peptide Signature Database | |
| XMAn | a Homo sapiens mutated-peptide database for the MS analysis of cancerous cell states. | |
| Mycosec | A database for signal peptide bearing genes of mycobacterium | |
| ANTIMIC | a database of antimicrobial sequences | |
| AMSdb | Antimicrobial sequences database | |
| BIOPD | a web-based information center for bioactive peptides |