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Immuno-informatics

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  • Types of Antibody

  • Antibody Basics
  • Polyclonal Antibody
  • Monoclonal Antibody
  • Recombinant Antibody
  • Chimeric Antibody
  • Antibody Phage Display
  • Humanized Antibody
  • Superantibody
  • Catalytic antibody

  • Antibody : Resources

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  • Antibody: Validation
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  • Antibody: Sequencing
  • Antibody: Literature

  • Techniques and Protocols

  • ELISA Radioimmunoassay
  • Antibody Microarrays

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  • Antibody: Literature


    Articles

  • Development trends for human monoclonal antibody therapeutics (Nature Reviews Drug Discovery 2010)
  • Characterization of a humanized anti-CD20 antibody with potent antitumor activity against B-cell lymphoma (Cancer Letters 2010)
  • Engineered antibodies (Nature Medicine 2003)
  • Generating recombinant antibodies to the complete human proteome (Trends in Biotechnology 2010)
  • Antibodies:The generation game (Nature 2007)
  • HAHA-nothing to laugh about (Journal of Pharmaceuticals and Biomedical Analysis 2010)
  • Human antibodies from transgenic animals (Nature Biotechnology 2005)
  • Monoclonal antibody successes in the clinic (Nature Biotechnology 2005)
  • High throughput production of mouse monoclonal antibodies using antigen microarrays (Proteomics 2005)
  • An antigen microarray immunoassay for multiplex screening of mouse monoclonal antibodies (Nature Protocols 2010)
  • Man made antibodies (Nature 1991)
  • A plastic antibody (JACS 2010)
  • Humanized antibody and their application (Methods 2005)
  • Chimeric antibodies: Production and applicaation (Methods 1995)
  • Antibody validation (BioTechniques 2010)
  • Genration and production of engineered antibodies (Molecular Biotechnology 2004)
  • Automated de novo protein sequencing of monoclonal antibodies (Nature Biotechnology 2008)
  • Therapeutic applications of superantibodies (Drug Discovery Today 2005)
  • Superantibodies: Synergy of innate and acquired immunity (Applied Biochemistry & Biotechnology 2000)
  • Superantibody activity: new players in innate and adaptive responses (Immunology Today 1998)

    Patents

  • Recent patent application in antibody fragments by Nature Publications
  • Super Humanized Antibodies (2010)
  • Books

    Antibodies: A Laboratory Manual
    Ed Harlow and David Lane
    (Cold Spring Harbor Laboratory Press, 1988)
    This well known book contains chapters on the immune response, structure of the antibody molecule, the activities of antibodies and the mechanism of antibody response. It also contains protocols for raising, purifiying, and labeling monoclonal and polyclonal antibodies as well as chapters describing ways of using antibodies to study antigens.

    Journals

  • Nature
  • Cell
  • Science
  • Protein Science
  • Journal of Biological Chemistry
  • Human Antibodies
  • Immunity
  • Annual Review of Immunology